• 한국동물학회지
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• 제38권2호
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• pp.167-176
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• 1995

Glucose-regulated proteins (grp's), srp94 3nd grp78/BiP, are a group of stress proteins which are highly synthesized in cells exposed to a variety of stressful agents including tunicamycin 3nd Ca2+ ionophore. Grp78/BiP is hon to function as a molecular chaperone which regulates the folding and assembly of secretory or membrane proteins, but the biological function of grp941 remains to be elucidated. In this study, we have examined the intracellular distribution of grV's and the function of srp94. Grp's are resident in the endoplasmic reticulum (ERI 3nd a specific sequence (Lys-Asp-Glu-Leu) at their C-terminus is known to be responsible for their retention within the ER. However, it has been unclear whether upon disturbance of cellular Caa+ homeostasis by the Ca2+ ionophore, grp94 is retained within the ER or secreted into the medium. In this study, we showed that in the presence of C3a+ ionophore, grp94 and gif78/BiP are present in the cells, mainly within the ER. We have also investigated whether grp94 might function as a molecular chaperone. Here we showed that in the immunoglobulin (Ig)-secreting hvbridom3 cells, grp94 transientlY interacts with fully glycosylated Is heavy chain, suggesting that grpg94 may be involved in facilitating the folding and assembly of Ig heavy chains.

• 한국정보통신설비학회:학술대회논문집
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• 한국정보통신설비학회 2008년도 정보통신설비 학술대회
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• pp.355-359
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• 2008

와이브로(WiBro), 3G 무선인터넷(HSDPA), 3G LTE 등과 같은 와이어리스 브로드밴드(Wireless Broand) 기술이 점차 성숙됨에 따라 이들 망을 활용한 다양한 무선인터넷 서비스를 제공하려는 사업자들이 증가하고 있다. 기존의 WLAN, 2G/3G 회선망에서의 제한된 이동성 및 네트워크 전송 속도를 개선한 와이어리스 브로드밴드 서비스 시장은 국내에서도 2006년부터 WiBro 및 HSDPA가 사용됨에 따라 사업자간의 경쟁도 본격화되고 있다. 이러한 환경 속에서 사업자들은 신속하고 편리한 서비스 개통과 스마트폰, USB모뎀, 노트북, UMPC, PMP등 다양한 단말들의 펌웨어 업그레이드, A/S 처리 방안에 대해 고심을 하고 있으며, 이들 문제점은 막대한 비용과 고객 민원을 야기시키는 요인이기도 하다. 따라서 경제적인 관리비용으로 동적인 서비스/펌웨어 업그레이드 및 A/S에 대한 고객 만족도를 높이기 위한 단말 원격 관리 필요성이 절실히 요구된다. WiBro 단말의 안전하고 효율적으로 관리하기 위해서는 단말과 기지국사이의 무선구간에 대한 보안(security)을 강화시켜 줄 수 있으면서 이동성(mobility)을 고려한 OMA DM프로토콜을 이용하는 것이 적합하다. 또한, WiBro에서 가입자 인증을 채택하고 있는 UICC의 관리를 위해서 3GPP에서 정의하는 SMS/MMS기반의 또는 BIP(Bear Independent Protocol)기반의 OTA기술을 병행하여 사용하여야 한다. 본 논문에서는 Wi-MAX단말 관리를 위한 OTA Provisioning 규격으로 OMA DM과 TR069이 WiMAX 단말을 위하여 어떻게 적용하도록 규정하고 있는지를 살펴본다. 특히, WiBro 가입자 인증뿐만 아니라 폰북, DRM, 금융서비스 등 다양한 부가 서비스를 위하여 사용되는 UICC의 원격관리를 위한 관리 요소들을 정의, 설계하고 이를 바탕으로 구현된 KTUICC OTA Provisioning시스템을 소개한다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권5호
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• pp.1708-1734
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• 2022

In the development of logistics system, the breakthrough of important technologies such as technology platform for logistics information management and control is the key content of the study. Based on Javascript and JQuery, the logistics system realizes real-time monitoring, collection of historical status data, statistical analysis and display, intelligent recommendation and other functions. In order to strengthen the cooperation of warehouse storage, enhance the utilization rate of resources, and achieve the purpose of real-time and visual supervision of transportation equipment and cargo tracking, this paper studies the VNF dynamic deployment and SFC routing problem in the network load change scenario based on the logistics system. The BIP model is used to model the VNF dynamic deployment and routing problem. The optimization objective is to minimize the total cost overhead generated by each SFCR. Furthermore, the application of the SFC mapping algorithm in the routing topology solving problem is proposed. Based on the concept of relative cost and the idea of topology transformation, the SFC-map algorithm can efficiently complete the dynamic deployment of VNF and the routing calculation of SFC by using multi-layer graph. In the simulation platform based on the logistics system, the proposed algorithm is compared with VNF-DRA algorithm and Provision Traffic algorithm in the network receiving rate, throughput, path end-to-end delay, deployment number, running time and utilization rate. According to the test results, it is verified that the test results of the optimization algorithm in this paper are obviously improved compared with the comparison method, and it has higher practical application and promotion value.

• Journal of Information Processing Systems
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• 제20권1호
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• pp.85-92
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• 2024

In recent years, Bitcoin and Ethereum have witnessed a surge in trading activity, driven by venture capital investment and funding through initial coin offerings (ICOs) and initial exchange offerings (IEOs). This heightened interest has led to kickstarting a vibrant ecosystem for blockchain development. The total number of cryptocurrencies listed on CoinMarketCap.com has reached 2,274 highlights how dynamic and wide blockchain development landscape has grown. In blockchain development, new blockchain projects are being created by forking blockchains inspired by major cryptocurrencies such as Bitcoin and Ethereum. These projects aim to address the perceived shortcomings and improve existing technologies. Altcoins, representing these alternative cryptocurrencies, are an ongoing industry effort to improve performance and security with enhancement proposals such as Bitcoin Improvement Proposals (BIP), Ethereum Improvement Proposals (EIP), and EOSIO Enhancement Proposals (EEP). With competitive attempts to improve blockchain performance and security, an ongoing performance race between various blockchains has taken shape, each claiming its own performance advantages. In this paper, we describe the transactions contained in the blocks of each representative blockchain, and find the factors that affect the transactions per second (TPS) through transaction processing and block generation processes, and suggest their relationship with scalability.

• Nuclear Engineering and Technology
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• 제56권6호
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• pp.2079-2091
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• 2024

In this paper, a model is developed for calculating pH in the presence of organic impurities due to dissolution of paint and/or continuous injection of organic impurities in the sump. The model is implemented in the AnCheBi code for the analysis of chemical behaviors of the iodine in the containment when the pH changes during a severe accident. Validation of the model is performed with P10T2 and P11T1 experiments carried out by AECL in Canada under the BIP project. Importance analyses of the pH calculation model in the AnCheBi code are then performed with the aforementioned experimental data via Latin hypercube sampling on the reaction coefficients, sensitivity analyses of AnCheBi, and calculation of the correlation coefficients between the reaction coefficients and figure of merits (the pH and the concentrations of the various iodine species). From the importance analyses, we provide the sensitivity of the pH calculation model to the change of pH and the concentrations of the various iodine species and the reaction coefficients related with the dominant phenomena underlying the change of pH and the concentrations of the species.

• 한국환경복원기술학회지
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• 제16권2호
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• pp.41-52
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• 2013

Anyang Stream Restoration Movement was started from 2001 for the construction of ecological city. The facilities for reuse of treated sewerage have been used since 2003 for improvement of water quality, maintenance of water quantity, river ecological restoration, and hydrophilic space. Thus, the Anyang city has been gradually transformed to eco-friendly city after the construction of Anyang stream and Hakui stream as natural rivers. In this study, biological and chemical methods as well as ecological indicators for Anyang mainstream and major tributaries were monitored for four years in between 2008 and 2012. The water quality and the diversity of species in most of the streams were found to be good except Anyang main stream. It appears that the influence of seasonal drying stream is almost disappeared except Sammak stream. Thus, the values for BOD (Biochemical Oxygen Demand) and BIP (Biological Index of Pollution) for Anyang main stream were found to be 5.27~3.42mg/l and 4.51~5.50, respectively. This is considered to be caused by the reused water quality of treated wastewater being exceeded the design criteria or by the non-point source of contaminants around the stream. However, entire section of tributaries shows I, II grade as a good water quality.

• 대한지리학회지
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• 제32권2호
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• pp.155-174
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• 1997

1994년 1월 1일 이후부터 공식적으로 발효한 NAFTA로 인하여 200l년 1월 1일까지는 멕시코ㆍ미국ㆍ캐나다 사이에 관세가 완전히 철폐될 예정이다. 패시코 북부지역의 변화는 이 지역의 도시성장에서 잘 나타나고 있다. 특히 국경지대에서 쌍둥이 도시화가 매우 급속히 진행되었다. 오늘날 멕시코 도시 순위 10위권 이내에 드는 세 도시(Ciudad Juarez, Tijuana, Mexicali)가 북부 국경지대에 위치한다. 멕시코 북부지역은 동서의 교류보다는 남북의 교류가 많았다. NAFTA로 인하여 멕시코 북부의 여러 하부지역들은 동서로 통합되는 것이 아니라 남북으로 통합되는 경향이 강화될 것으로 예측된다. 멕시코 북부 국경지대의 산업 발달은 멕시코인들에게는 고용기회를 확대시키고 미국인들에게는 저렴한 노동력을 이용할 수 있는 기회를 부여한다. NAFTA는 경제수준의 차가 큰 두 체제 사이의 경제통합이라는 점에서 향후 전세계적으로 전개될 지도 모르는 지역주의적 경제통합에 시사하는 바가 크다고 하겠다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2019년도 추계학술대회
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• pp.25-25
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• 2019

Chromosome numbers and karyotypes in flowering plants have been considered to be prominent features in taxonomic and evolutionary context. Despite the increasing numbers of cytological studies in Asteraceae, karyotype analysis of Cirsium Mill. and Carddus L. in Korean population have not been performed carefully. In this study, the chromosome numbers and karyotype analysis of all eight species of the genus Cirsium Mill. and one species of Carddus L. were analyzed. While the chromosome number in Carduus crispus L. was diploid (2n = 2x = 18 or 18+2Bs) with x = 9 as the base chromosome number, all seven species of Cirsium were diploid with x = 17 except for Cirsium lineare (Thunb.) Sch. Bip. (x = 14). The chromosome number in C. pendulum Fisch. ex DC. presented 2n = 2x = 34 from two populations and C. lineare exhibited 2n = 2x = 28 from one population. Aneuploidy was occasionally found in C. japonicum Fisch. ex DC. var. spinossinum Kitam. (2n = 2x = 34, 35, 36), C. rhinoceros (H. $L{\acute{e}}v.$ & Vaniot) Nakai (2n = 2x = 32, 34), C. setidens (Dunn) Nakai (2n = 2x = 30, 31, 32) and C. vlassovianum Fisch. ex DC. (2n = 2x = 31, 32). While Cirsium japonicum Fisch. ex DC. var. japonicum possessed several B-chromosomes (2n = 2x = 34, 35, 36), polyploidy was only encountered in Cirsium nipponicum (Maxim.) Makino. (2n = 4x = 68) from two populations in Ulleung Island. The present cytological data might be contributed to the taxonomic and evolutionary studies in the genus Cirsium.

• 한국자원식물학회지
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• 제26권2호
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• pp.248-270
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• 2013

본 연구는 경상북도 경주시에 위치한 금곡산의 관속식물상을 조사 및 분석함으로서 식물생태계의 보전을 위한 기초 자료 수집에 목적이 있다. 금곡산의 관속식물은 91과 298속 397종 4아종 46변종 6품종 등 총 453분류군으로 요약되었다. 산림청 지정 희귀식물은 변산바람꽃, 솜양지꽃, 노랑무늬붓꽃 등 3분류군으로 나타났다. 한국특산식물은 서어나무, 변산바람꽃, 고광나무, 해변싸리, 노랑갈퀴, 병꽃나무 등 6분류군으로 확인되었다. 식물구계학적 특정식물은 잣나무, 왕버들, 꿩의바람꽃, 홀아비꽃대, 대극, 대팻집나무, 조개나물, 빗살서덜취, 노랑제비꽃, 물박달나무, 좀목형, 승마 등 36분류군으로 나타났다. 귀화식물은 닭의덩굴, 다닥냉이, 아까시나무, 토끼풀, 애기땅빈대, 둥근잎나팔꽃, 큰개불알풀, 울산도깨비바늘, 지느러미엉겅퀴, 큰도꼬마리, 큰이삭풀, 큰김의털 등 36분류군이 확인되었다. 생태계교란야생동식물은 돼지풀, 미국쑥부쟁이 등 2분류 군이었다. 도시화지수(UI)는 11.2%, 귀화율(NI)은 7.9%, 교란율(DI)은 18.2%로 분석되었다.

• 생명과학회지
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• 제20권12호
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• pp.1820-1828
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• 2010

PC12 세포에서 $CoCl_2$에 의한 hypoxia 유도는 HIF1 alpha의 상승 발현으로 확인하였다. 이때 apoptosis의 유도는 genomic DNA의 fragmentation과 apoptotic body는 Hoechst 염색으로 확인되었고, ER luminal chaperone의 발현 및 ER stress signal에 관여하는 ER membrane kinase인 IRE1, PERK, ATF6의 발현도 확인되었다. 이들이 apoptosis로 연결되는 고리 역할을 하는 IRE1-XBP1 mRNA splicing, PERK-eIF2 alpha, ATF6 protein cleavage도 반응하는 것으로 확인되었다. 위의 결과는 신경세포의 hypoxia상태는 ER stress signal pathway를 거쳐서 apoptosis가 된다는 것을 증명한 것으로 신경세포의 hypoxia치료를 위한 기초 자료가 될 것으로 생각한다.