• Journal of Environmental Health Sciences
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• v.23 no.1
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• pp.43-49
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• 1997

This study was aimed to estimate removal efficiency(%) of BER(Biofilm-Electrode Reactor) and A.S(Activated Sludge) treatments. When were analyzed COD$_{Cr}$, NH$_3$-N and T-P by current density and reaction time, the results were as follows : 1) In BER treatment, the removal efficiency of COD$_{Cr}$ in domestic wastewater was 79-86% when current density was 2.39 mA/dm$2$(15mA)-3.98 mA/dm$^2$(25mA) and reaction time was 48 hr. 2) Removal efficiency of NH$_3$-N was 71-73% when current density was 2.39-3.98 mA/dm$^2$ and reaction time 48 hr. 3) When the reaction time was 48 hr removal efficiency(%) of BER treatment for COD$_{Cr}$, NH$_3$-N and T-P were more excellent than A.S. treatment. And then we prospect that was because activated microorganism colonies attached in biofilm on surface of electrode pannel. Therefore, In order to derive BER treatment efficiency(%) should establish optimum conditions of pH, temp., reaction time, current density and biochemical and electrochemical states.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.2
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• pp.79-89
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• 2012

We examine whether Phellodendron amurense (PA) and its major alkaloid compound, berberine (BER), improved memory defects caused by administering scopolamine in rats. Effects of PA and BER on the acetylcholinergic system and pro-inflammatory cytokines in the hippocampus were also investigated. Male rats were administered daily doses for 14 days of PA (100 and 200 mg/kg, i.p.) and BER (20 mg/kg, i.p.) 30 min before scopolamine injection (2 mg/kg, i.p.). Daily administration of PA and BER improved memory impairment as measured by the passive avoidance test and reduced the escape latency for finding the platform in the Morris water maze test. Administration of PA and BER significantly alleviated memory-associated decreases in cholinergic immunoreactivity and restored brain-derived neurotrophic factor and cAMP-response element-binding protein mRNA expression in the hippocampus. PA and BER also decreased significantly the expression of proinflammatory cytokines such as interleukin-$1{\beta}$, tumor necrosis factor-${\alpha}$ and cyclooxygenase-2 mRNA in the hippocampus. These results demonstrated that PA and BER had significant neuroprotective effects against neuronal impairment and memory dysfunction caused by scopolamine in rats. These results suggest that PA and BER may be useful as therapeutic agents for improving cognitive functioning by stimulating cholinergic enzyme activity and alleviating inflammatory responses.

• Journal of Pharmacopuncture
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• v.22 no.2
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• pp.90-94
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• 2019

Objectives: Paclitaxel (PTX) as an anticancer drug used against solid cancers, possesses adverse reactions such as neuropathic pain which has confined its use. PTX-induced neuropathic pain is mediated via activation of oxidative stress. Berberine (BER), an isoquinoline phytochemical found in several plants, exerts strong antioxidant and painkilling properties. In the current study, we aimed to evaluate pain-relieving effect of BER in a mouse model of PTX-induced neuropathic pain. Methods: This study was done using 42 male albino mice that were randomly divided into 6 groups (n = 7) as follow: Sham-operated (not treated with PTX), negative control group (PTX-treated mice receiving normal saline), BER 5, 10, and 20 mg/kg (PTX-treated mice receiving BER) and positive control group (PTX-treated mice receiving imipramine 10 mg/kg). Neuropathic pain was induced by intraperitoneal administration of four doses of PTX (2 mg/kg/day) on days 1, 3, 5 and 7. Then, on day 7, hot plate test was done to assess latency to heat to measure possible anti-neuropathic pain effect of BER. Results: Four doses of PTX 2 mg/kg/day induced neuropathy that was reduced by BER at all time-points (i.e. 0, 30, 60, 90 and 120 min) after injection (P < 0.001 in comparison to control). The statistical analysis of data showed significant differences between groups (P < 0.001 in comparison to negative control), at 30, 60, 90 and 120 min after injection of BER 5, 10 and 20 mg/kg; in other words, 30, 60, 90 and 120 min after BER administration, neuropathic pain was significantly reduced as compared to normal saline-treated mice. Conclusion: Altogether, our results showed that PTX could induce neuropathic pain as reflected by hyperalgesia and BER could alleviate PTX-induced thermal hyperalgesia.

• IT SoC Magazine
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• s.19
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• pp.37-42
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• 2007

이 글은 당사에서 개발 진행한 TDMB,ISDB-T등의 Moblie TV Receiver단의 Analog Front-End SIP들의 Test H/W, S/W제작 경험을 바탕으로 보다 효율적이고 성공적인 SIP 개발이 될 수 있도록 도움을 주고자 기술 하였다.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.1
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• pp.83-85
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• 2012

The causes of blossom-end rot (BER) are still not understood clearly, although there was a lot of research on the development of BER over 100 years. This experiment was conducted to investigate the influence of Ca content of fruit on the incidence of BER in red pepper. BER affected fruits and healthy fruits had been harvested and the samples were divided into two parts, the upper and the lower, for chemical analysis to determine the content of mineral nutrients in the tissue. The content of nitrogen (N), phosphorus (P), potassium (K) and magnesium (Mg) was higher in the BER affected fruits and the difference of each nutrient content was revealed much larger in the lower part of the fruit but there were no significant differences in calcium content between the BER and the healthy fruits of red pepper, in this experiment. The results indicate that it is difficult to find a certain relation between the calcium content of the fruit and the occurrence of blossom-end rot.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.3 no.4
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• pp.795-804
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• 1999

The increasing number of users of mobile communication systems and the corresponding need for increased system capacity require the use of a modulation scheme which is both power and spectrally efficient. In this paper, we numerically calculate the BER performance of DS/CDMA-BPSK system in different fading channel (Rayleigh, Rician, Shadow Rician). Also, we calculate BER performance and the channel capacity of DS/CDMA-BPSK system which is constant or nearly constant envelopes in 3-state fading channel model. The Shadow Rician fading model described in this paper apply the parameters of the Canadian Mobile Satellite (MSAT). And we assume that the 3-state fading channel model is consist of Rayleigh fading state, Rician fading state, and shadow Rician fading state. This model can be used as a basis for the simulation of the land mobile satellite channel. The dynamic 3-state fading channel model is considered corresponding to different environments and the transitions between these environments. From the numerically calculate results, the DS/CDMA-BPSK system with MUI-20, PG-511 can not achieve the BER performance ($P_b\leq10^{-5}$). And the channel capacity did not meet the system requirement. Also, we know that the BER performance is depend m the occupancy probability of radio channel and the degree of shadow. From the results, we how that during shadowed time intervals it is necessary to use some form of error control coding and receiver diversity in order to support reliable data communication.

• Journal of Pharmacopuncture
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• v.7 no.1 s.12
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• pp.53-61
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• 2004

Substantial evidence suggests that behavioral and reinforcing effects of cocaine can be mediated by the mesolimbic dopaminergic system. It has been shown that repeated injections of cocaine produce increase in locomotor activity, expression of the immediate-early gene, c-fos in the nucleus accumbens (NAc), which was one of the main dopaminergic terminal areas. Herbal-acupuncture as a therapeutic intervention has been widely used for the treatment of many functional disorders such as drug abuse. Coptidis Rhizoma (CR) and its main component, berberine (BER) were selected as herbal medicine of herbal-acupuncture. Both medicines have been known to have the therapeutic effect on the central nervous system. In order to investigate the effects of CR and BER herbalacupuncture at shenmen (HT7) point (CR/H and BER/H) on the cocaine-induced behavioral sensitization, the influence of CR/H and BER/H on repeated cocaine-induced locomotor activity, the change of c-Fos expression in the brain by immunohistochemistry were examined. Male SD rats were given CR/H (0.4mg/kg) and BER/H (0.1mg/kg) 30 min before daily injections of cocaine hydrochloride (15mg/kg. i.p.) 10 days. After 3 days withdrawal, rats received a challenge injection of cocaine (15mg/kg, i.p.). Systemic challenge with cocaine produced much larger increased locomotor activity, accumbal Fos-like immunoreactivity in the NAc. Pretreatment with CR/H and BER/H significantly inhibited cocaine-induced locomotor activity, the change of c-Fos expression in the rats. Our data demonstrated that the inhibitory effects of cocaine-induced behavioral sensitization by CR/H and BER/H were closely associated with the reduction of presynaptic dopamine release in the NAc. These results suggest that CR/H and BER/H can be effectively applied to cocaine addiction.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.1
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• pp.117-123
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• 2013

By calculating the spectral efficiency of symmetric balance incomplete block design(BIBD) codes satisfying BER=$10^{-9}$, it can be found that ideal BIBD code design with m=2 and various q's is effective when effective power is high($P_{sr}=-10$ dBm). But BIBD code design with q > 2 and various m's can be effective when effective power is low($P_{sr}=-25$ dBm).

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.11
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• pp.2062-2068
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• 2006

In his paper, embedded system implementation for IEEE802.l1p based OFDM-DSRC is presented. After the IEEE802.11p physical layer specification is introduced and BER performance of the modem is evaluated by simulation, implementation aspects of the system such as system architecture, design method and implementation results are addressed. Implemented embedded system for the OFDM-DSRC communication consists of FPGA, flash memory, ARM9 CPU Core, peripherals, etc. from the results, it is shown that the implemented system operates well according to IEEE802.11p specification. It is expected that implemented embedded system shall be used for wireless communication system such as ITS application by enhancing system optimizing.

• Bulletin of the Korean Space Science Society
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• 2007.04a
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• pp.73-73
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• 2007