• Korean Journal of Radiology
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• v.24 no.11
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• pp.1151-1163
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• 2023

Objective: To develop a deep-learning-based bone age prediction model optimized for Korean children and adolescents and evaluate its feasibility by comparing it with a Greulich-Pyle-based deep-learning model. Materials and Methods: A convolutional neural network was trained to predict age according to the bone development shown on a hand radiograph (bone age) using 21036 hand radiographs of Korean children and adolescents without known bone development-affecting diseases/conditions obtained between 1998 and 2019 (median age [interquartile range {IQR}], 9 [7-12] years; male:female, 11794:9242) and their chronological ages as labels (Korean model). We constructed 2 separate external datasets consisting of Korean children and adolescents with healthy bone development (Institution 1: n = 343; median age [IQR], 10 [4-15] years; male: female, 183:160; Institution 2: n = 321; median age [IQR], 9 [5-14] years; male: female, 164:157) to test the model performance. The mean absolute error (MAE), root mean square error (RMSE), and proportions of bone age predictions within 6, 12, 18, and 24 months of the reference age (chronological age) were compared between the Korean model and a commercial model (VUNO Med-BoneAge version 1.1; VUNO) trained with Greulich-Pyle-based age as the label (GP-based model). Results: Compared with the GP-based model, the Korean model showed a lower RMSE (11.2 vs. 13.8 months; P = 0.004) and MAE (8.2 vs. 10.5 months; P = 0.002), a higher proportion of bone age predictions within 18 months of chronological age (88.3% vs. 82.2%; P = 0.031) for Institution 1, and a lower MAE (9.5 vs. 11.0 months; P = 0.022) and higher proportion of bone age predictions within 6 months (44.5% vs. 36.4%; P = 0.044) for Institution 2. Conclusion: The Korean model trained using the chronological ages of Korean children and adolescents without known bone development-affecting diseases/conditions as labels performed better in bone age assessment than the GP-based model in the Korean pediatric population. Further validation is required to confirm its accuracy.

• Korean Journal of Cognitive Science
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• v.34 no.4
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• pp.259-275
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• 2023

The aim of this study was to investigate font change blindness based on text difficulty in the "Moving Window Task", as originally introduced by McConkie and Rayner(1975). During the reading process where the moving window was applied, different target words in terms of font style compared to the text were presented. As participants' gaze reached the position of the target word, the font of the target word was changed to match the text font. The font of the target word before the change was either sans-serif when the text font was serif, or serif when the text font was sans-serif. After completing the reading task, more than half of the participants(62.5%) reported not detecting the font change. Observation of eye movements at the target word positions revealed that when understanding the content within the text was difficult, there was an increase in the number of regressions, an extended gaze duration, and a reduction in saccade length. Specifically, the increase in the number of regressions was evident only when the text font was serif, in other words, when the font of the target word shifted from sans-serif to serif. These results suggest that sensory interference unrelated to content understanding is not easily detected during reading. However, the possibility of detection increases when comprehension of the content becomes challenging. Furthermore, this exceptional detection possibility implies that it may be higher when the text font is serif compared to when it is sans-serif.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1464-1474
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• 2023

The purpose of this study is a descriptive study to identify the five factors of personality and grit on academic burnout of nursing students. The subjects of the study were 285 nursing college students attending the department of nursing located in S city. Data were collected through a self-report questionnaire from April 11 to June 13. Data were analyzed using SPSS/WIN 29.0 program with descriptive statistics, the independent t-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression analysis. In the result of this study, academic burnout had a negative correlation with grit(r=-.425, p<.001), agreeableness(r=-.330, p<.001). On the other hand, it showed a positive correlation with neuroticism (r=.384, p<.001). Two personality factors(neuroticism, agreeableness), major satisfaction, and grit were found to have a significant impact on academic burnout in nursing students. Therefore, It is necessary to develop counseling methods that can prevent academic burnout by utilizing the five personality factors of nursing students and to develop programs that can increase major satisfaction and grit and reduce academic burnout.

• Herbal Formula Science
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• v.32 no.1
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• pp.51-61
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• 2024

Objectives : This study induced oxidative stress in HepG2 cells by treating them with AA+iron and investigated the effects of forsythia suspensa extract on this stress, as well as elucidated the molecular mechanisms underlying its hepatoprotective effects. Methods : To confirm the antioxidative effects of FSE, HepG2 cells were induced with AA+iron to induce oxidative stress, followed by MTT assay. Additionally, the effect of FSE in reducing the increased ROS levels and mitochondrial damage induced by AA+iron in HepG2 cells was confirmed using FACS. Furthermore, western blot analysis were conducted to investigate the molecular mechanisms underlying the hepatoprotective effects of FSE. Results : FSE increased the decreased cell viability induced by AA+iron. Additionally, FSE normalized the expression of apoptosis-related proteins induced by AA+iron. The elevated ROS levels in HepG2 cells induced by AA+iron were reduced by FSE, and the increase in Rh123-negative cells induced by AA+iron was attenuated by FSE. Moreover, FSE activated the protein expression of AMPK and its related phosphorylating enzymes, LKB1 and ACC. Furthermore, FSE activated YAP and its upstream phosphorylating enzyme, LATS1. Conclusions : These results demonstrate that FSE has an inhibitory effect on oxidative stress induced by AA+iron and may have potential hepatoprotective effects.

• Tunnel and Underground Space
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• v.34 no.1
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• pp.1-14
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• 2024

An image-reconstruction technology, involving the deployment of an unmanned mobility equipped with high-speed LiDAR (Light Detection And Ranging) has been proposed to reconstruct the shape of abandoned mine. Unmanned mobility operation is remarkably useful in abandoned mines fraught with operational difficulties including, but not limited to, obstacles, sludge, underwater and narrow tunnel with the diameter of 1.5 m or more. For cases of real abandoned mines, quadruped robots, quadcopter drones and underwater drones are respectively deployed on land, air, and water-filled sites. In addition to the advantage of scanning the abandoned mines with 2D solid-state lidar sensors, rotation of radiation at an inclination angle offers an increased efficiency for simultaneous reconstruction of mineshaft shapes and detecting obstacles. Sensor and robot posture were used for computing rotation matrices that helped compute geographical coordinates of the solid-state lidar data. Next, the quadruped robot scanned the actual site to reconstruct tunnel shape. Lastly, the optimal elements necessary to increase utility in actual fields were found and proposed.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.137-144
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• 2024

This study shows the effectiveness of mental health by applying the Light of the Mind program to 45 nursing students who applied for the Human Relations class at JS University and showed 90% attendance once a week for a total of 10 sessions and 60 minutes per session. The 'Light of the Heart' program was carried out in the Simsang-Poetry therapy stage and technique, an integrated art and cultural therapy that recognizes the 'light' representing 'inner positivity'. As a result of phenomenological and qualitative analysis of the participants' descriptions, the categories of source, healing power, positive perception, self-realization, positive emotion, potential, and self-awareness were shown, and there was a statistically significant difference in the experimental group compared to the control group when analyzing before and after the resilience scale. This study is significant in that it improved the mental health of nursing students through human relations classes. It is necessary to develop and carry out various programs for the promotion of human relations and mental health of college students, and it will be helpful to the mental health of modern people by expanding this program to the general public.

• Journal of the Korean Society of Radiology
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• v.85 no.2
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• pp.394-408
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• 2024

Purpose To develop models to predict programmed death ligand 1 (PD-L1) expression in pulmonary squamous cell carcinoma (SCC) using CT. Materials and Methods A total of 97 patients diagnosed with SCC who underwent PD-L1 expression assay were included in this study. We performed a CT analysis of the tumors using pretreatment CT images. Multiple logistic regression models were constructed to predict PD-L1 positivity in the total patient group and in the 40 advanced-stage (≥ stage IIIB) patients. The area under the receiver operating characteristic curve (AUC) was calculated for each model. Results For the total patient group, the AUC of the 'total significant features model' (tumor stage, tumor size, pleural nodularity, and lung metastasis) was 0.652, and that of the 'selected feature model' (pleural nodularity) was 0.556. For advanced-stage patients, the AUC of the 'selected feature model' (tumor size, pleural nodularity, pulmonary oligometastases, and absence of interstitial lung disease) was 0.897. Among these factors, pleural nodularity and pulmonary oligometastases had the highest odds ratios (8.78 and 16.35, respectively). Conclusion Our model could predict PD-L1 expression in patients with lung SCC, and pleural nodularity and pulmonary oligometastases were notable predictive CT features of PD-L1.

• The Korean Journal of Quaternary Research
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• v.32 no.1_2
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• pp.1-29
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• 2018

We investigated the seasonal variation of diatoms from the modern bottom floor sediments of the reservoirs distributed in the southern part of the Korean Peninsula. The studied reservoirs include each three reservoirs from Southeastern part, Central Southern part and Southwestern part, respectively, to compare the dominant diatom assemblages that are ecologically controlled by local environments. In the Southeastern region, Aulacoseira spp., Fragilaria crotonensis, Fragilaria tenera, Gomphonema gracile, G. parvulum and Gyrosigma attenuatum were dominant species. Aulacoseira spp., Cymbella tumida, Cymbella turgidula, Diploneis finnica and Fragilaria crotonensis were dominant taxa in the Central Southern regions. In the southwestern region, Aulacoseira spp., Fragilaria crotonensis, Gomphonema parvulum and Stenopterobia curvular were predominated. Of which Aulacoseira spp. were predominant species at all reservoirs. In addition most of dominants are saproxenous taxa living in the clean water area, and the water quality of these reservoirs is considered to be less polluted water. As a result of seasonal comparison of diatom productivity, the first productivity is higher in summer than in winter. However, diatom valve abundance in the southeastern reservoirs was fewer from the samples collected at May than February.

• Journal of agricultural medicine and community health
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• v.30 no.2
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• pp.137-149
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• 2005

Objectives and Methods: This study was performed to investigate the etiologic bacterial, viral and protozoal organisms for the diarrhea from hospitals in Chungnam area from January to December in 2004. Total of 787 fecal samples were collected and examined. Results and Conclusions: In test for enteropathogenic bacteria, total of 79 cases out of 787 samples from hospitals showed positive isolation. Among 79 positive samples, 27 cases were confirmed as Salmonella spp.. 20 cases as pathogenic E. coli, 18 cases as Clostridium perfringens, 6 cases as Staphylococcus aureus, 4 cases as Shigella spp. and 4 cases as Vibrio parahaemolyticus. In test for enteropathogenic virus, 190 cases out of 787 samples from hospitals showed positive reaction. Among 190 samples, 115 cases were confirmed as rotavirus, 55 cases as norovirus, 5 case as astrovirus, 4 case as rotavirus & norovirus, 3 cases as adenovirus, 2 case as rotavirus & astrovirus. In test for enteropathogenic protozoa, 6 cases out of 787 samples from hospitals showed positive result. Among 6 samples, 5 cases were confirmed as Entamoeba histolytica and 1 cases as Giardia lamblia. When we classified the positive results by the age of the patients, the highest isolation rate was noted in a group of age under 10 and over 60 for bacterial, viral and protozoal pathogens. Especially, patient below age of 5 showed high positive rate. When we classified the positive results by the time, pageathogenic bacteria were isolated throughout the year, and the highest frequency was noted in August. On the other hand, pathogenic viruses were detected more frequently during the colder season from December to April. Antimicrobial susceptibility test for the isolated bacteria resulted as follows; Salmonella strains showed high drug resistance rates against ampicillin, chloramphenicol, tetracycline, nalidixic acid, ticarcillin. Shigella strains showed high drug resistance rates against ampicillin, trimethoprim/sulfamethoxazole, chloramphenicol, tetracycline, ampicillin/sulbactam, ticarcillin. Pathogenic E. coli strains showed high drug resistance rates against ampicillin, cephalothin, gentamicin, tetracycline, nalidixic acid, ampicillin/sulbactam, ticarcillin.

• The Journal of Korean Academy of Prosthodontics
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• v.46 no.4
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• pp.420-430
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• 2008

Statement of problem & Purpose: Articulators are very important for education and overall clinical situation in the field of prosthodontics, however preexisting articulators are designed and built based on maxillofacial structures and mean values of mandibular movement of Western people. Purpose of this research is to find out a adequate basis for applicating these articulators, presently used for clinical education, for Korean. Material and methods: 59 Korean adults (41 males, 18 females), aged between 24 to 41, where selected for this study. Two pairs of both maxillary and mandibular models were made for each examinee. These models where attached to both KaVo PROTARevo 7 and Hanau Modular semiadjustable articulators by using facebow transfer, than sagittal condylar inclination, occlusal plane inclination and position of mandibular on the articulator where measured. Result and conclusion: 1. Mean sagittal condylar inclination for KaVo PROTAR semiadjustable articulator was $33.75^{\circ}$(standard deviation $12.46^{\circ}$) meanwhile Hanau Modular semiadjustable articulator showed $40.72^{\circ}$(standard deviation $12.09^{\circ}$) for mean sagittal condylar inclination. 2. Mean occlusal plane inclination for KaVo PROTAR semiadjustable articulator was $-2.76{\circ}$(standard deviation $3.63^{\circ}$) meanwhile Hanau Modular semiadjustable articulator showed $11.87^{\circ}$ (standard deviation $3.63^{\circ}$) for mean occlusal plane inclination. 3. On the average center of the mandibular dentition were in the range of 5 to 7 mm of the central position of the articulator. Both anterior and posterior dentition were positioned at the center of the articulator vernacularly for KaVo PROTAR semiadjustable articulators, meantime for Hanau Modular semiadjustable articulator, anterior dentition was positioned 5 mm downwards and 3mm upwards for posterior dentition from vertically central position of the articulator.