• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2005년도 총회 및 춘계학술발표회
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• pp.308-311
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• 2005

[ $^{222}Rn\;and\;^{226}Ra$ ] in groundwater were determined simultaneously using a gamma-spectroscopy. A nitrogen flushing equipment has been used for elimination and stabilization of high and unstable background activity due to the radon and its progenies in counting shield and room. The aim of present work was to control the background activity for simultaneous measurement of radium$(^{226}Ra)$ and radon$(^{222}Rn)$ in groundwater using a gamma-spectrometry. Background activity was about 1.0dps and the standard deviation was about 50%, The background activity could be minimized using nitrogen flushing equipment in the range of 0.1 to 0.5 and the RSD was about 5% at the experimental condition. The detection limit of $^{222}Rn\;and\;^{226}Ra$ in groundwater was 0.5dps/L in the background control method. In most groundwater used in the work, radon activity was more than the detection limit. However, radium activity in some groundwater was less than the detection limit. If the low level radium in groundwater must be measured, preconcentration process such as concentration should be performed before measuring the groundwater.

• Nuclear Engineering and Technology
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• 제51권8호
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• pp.2013-2017
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• 2019

The radon concentrations in soil air were measured before and after a rainfall. ²²⁶Ra concentration, porosity, moisture content and temperature in soil were measured at Kyungpook National University in Daegu. As the results of measurement and analysis, the arithmetic mean of measured ²²²Rn concentration increased from 12100 ± 500 Bq/㎥ to 16200 ± 600 Bq/㎥ after the rainfall. And the measured ²²⁶Ra concentration was 61.4 ± 5.7 Bq/kg and the measured porosity was 0.5 in soil. The estimated values of ²²⁶Ra concentration and porosity using diffusion model of ²²²Rn in soil were 60.3 Bq/kg and 0.509, respectively. The estimated values were similar to the measured values. ²²²Rn concentration in soil increased with depth and moisture content. The estimations were obtained through fitting based on the diffusion model of ²²²Rn using the measurement values. The measured depth profiles of ²²²Rn were similar to the calculated depth profiles of ²²²Rn in soil. We hope that the results of this study will be useful for environmental radiation analysis.

• ETRI Journal
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• 제38권6호
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• pp.1153-1162
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• 2016

This paper addresses the resource allocation (RA) problem in multi-cell cognitive radio networks. Besides the interference power threshold to limit the interference on primary users PUs caused by cognitive users CUs, a proportional fairness constraint is used to guarantee fairness among multiple cognitive cells and the impact of imperfect spectrum sensing is taken into account. Additional constraints in typical real communication scenarios are also considered-such as a transmission power constraint of the cognitive base stations, unique subcarrier allocation to at most one CU, and others. The resulting RA problem belongs to the class of NP-hard problems. A computationally efficient optimal algorithm cannot therefore be found. Consequently, we propose a suboptimal RA algorithm composed of two modules: a subcarrier allocation module implemented by the immune algorithm, and a power control module using an improved sub-gradient method. To further enhance algorithm performance, these two modules are executed successively, and the sequence is repeated twice. We conduct extensive simulation experiments, which demonstrate that our proposed algorithm outperforms existing algorithms.

• IMMUNE NETWORK
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• 제13권6호
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• pp.257-263
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• 2013

Although pathogenesis of human rheumatoid arthritis (RA) remains unclear, arthritogenic T cells and downstream signaling mediators have been shown to play critical roles. An increasing numbers of therapeutic options have been added for the effective control of RA. Nevertheless, there is still a category of patients that fails treatment and suffers from progressive disease. The recently developed immunosuppressant CP-690550, a small molecule JAK kinase inhibitor, has been implicated as an important candidate treatment modality for autoimmune arthritis. In this study, we evaluated the therapeutic effect of CP-690550 on established arthritis using an SKG arthritis model, a pathophysiologically relevant animal model for human RA. CP-690550 treatment revealed remarkable long-term suppressive effects on SKG arthritis when administered to the well-advanced disease (clinical score 3.5~4.0). The treatment effect lasted at least 3 more weeks after cessation of drug infusion, and suppression of disease was correlated with the reduced pro-inflammatory cytokines, including IL-17, IFN-${\gamma}$, and IL-6 and increased level of immunoregulatory IL-10.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 추계학술대회
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• pp.310-313
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• 2016

최근 우리는 다양한 환경 하에서 수많은 안전사고를 마주하고 있다. 현재 연안 해상에서 활동 중 위험에 마주쳤을 경우에는 인간의 시야와 경험에만 의지한 구조 활동만 이루어지고 있다. 이에 따라 연안 해상 사고로 인한 사망 및 실종 사고가 많이 발생하고 있다. 이러한 사고는 주로 구조의 지연 때문에 발생한다고 볼 수 있다. 이러한 구조 지연에 따른 사고를 줄이기 위해서, 본 연구에서는 신속한 구조를 하기 위해 GPS, RF, LoRa 무선통신 기술 등 최신 IoT 기술을 이용해 누구나 손쉽게 사용할 수 있는 무선 송수신 단말기 제작에 대한 연구를 수행했다.

• IMMUNE NETWORK
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• 제22권4호
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• pp.36.1-36.12
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• 2022

Dexamethasone (DEX) was the first drug shown to save lives of critically ill coronavirus disease 2019 (COVID-19) patients suffering from respiratory distress. A hyperactivated state of neutrophils was found in COVID-19 patients compared to non-COVID pneumonia cases. Given the beneficial effects of DEX in COVID-19 patients, we investigated the effects of DEX and of other immunomodulatory drugs vitamin D3 (VD3) and retinoic acid (RA) on neutrophil function. DEX, but not VD3 or RA, significantly inhibited all tested aspects of neutrophil function, e.g., degranulation, intracellular ROS production, CXCL8 release and NETosis. Interestingly, RA displayed the opposite effect by significantly increasing both CXCL8 and NET release by neutrophils. Taken together, these data suggest that the lower COVID-19 mortality in DEX-treated patients may in part be due to the dampening effect of DEX on the inflammatory neutrophil response, which could prevent neutrophil plugs with NETS in the lungs and other inflamed organs of patients.

• The Korean Journal of Ecology
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• 제26권6호
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• pp.297-305
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• 2003

Fish fauna of mountain streams in the Jirisan National Park area of S. Korea (total area: 440.45 $\textrm{km}^2$, height: 1,915 m) was investigated at 33 sites from May 1997 to September 1999. A total of 4,670 individuals of fishes were collected and classified into 30 species and 12 families. Zacco temmincki (relative abundance (RA), 63.9%) was found to be the most abundant inhabitant. Subdominant species were Pungtungia hem (RA 6.2%), Zacco platypus (RA 6.1 %) and Coreoleusiscus splendidus (RA 4.8%). Among the total species, 13 species were identified as the Korean endemic species (7 families, 17.2% of 802 individuals). Dominant Korean endemic species was C. splendidus (relative abundance endemics (RAE), 27.8%). Superiors were Coreoperca heizi (RAE 21.8%) and Liobagrus mediadiposalis (RAE 19.8%). One exotic species (Oncorhynchus mykiss, a site and 5 ind.) and translated species (Hypmesus niponensis, two sites and 174 ind.) were collected in this survey. The proportion of Korean endemic species in the park (43.3%) was higher than the average of Korean Peninsular (25.9%). From this study, we conclude that the Jirisan National Park area in Korea would be very important for fish diversity and conservation, especially for the Korean endemic and endangered species.

• 한국임상약학회지
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• 제26권1호
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• pp.46-52
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• 2016

Background: The use of acid suppressive agents became a standard therapy in an intensive care unit (ICU) to prevent stress related gastrointestinal mucosal damage. However, the risk of infectious diseases has been concerned. Objective: The study was to determine the differences between histamine 2 receptor antagonists (H2RA) and proton pump inhibitors (PPI) in incidence of nosocomial pneumonia and pseudomembranous colitis (PMC) by Clostridium difficile with patients in ICU. Methods: This is a retrospective comparative study including patients admitted to the ICU who were at least 18 years of age and stayed for more than 48hrs from August 1, 2014 to January 31, 2015. The propensity score analysis and propensity matched multivariable logistic regression were used in analyzing data to control for confounders. Results: A total of 155 patients were assessed. H2RA were prescribed in 110 (53.9%) and PPI were in 45 (22.1%). Nosocomial pneumonia developed in 37 (23.9%); 25 (22.7%) were on H2RA and 12 (26.7%) were on PPI. The unadjusted incidence of nosocomial pneumonia was slightly higher in the patients with PPI (odds ratio (OR) 1.24; 95% confidence interval (CI): 0.54-2.71) compared to them with H2A. After adjusting with propensity score, the adjusted OR with PPI was 1.35 (95% CI: 0.44-4.11). The propensity score matched analyses showed similar results. Conclusion: The uses of PPI and H2RA as a stress ulcer prophylaxis agent showed similarity in the incidence of nosocomial pneumonia and PMC.

• 대한수의학회지
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• 제39권4호
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• pp.715-723
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• 1999

Bee venom (BV) has been traditionally applied to relieve pain and to cure inflammatory diseases such as rheumatoid arthritis (RA) and neuritis. While several investigators have evaluated the anti-inflammatory effect of BV treatment, the anti-nociceptive effect of BV treatment on inflammatory pain is not reported. Therefore, we decided to evaluate the analgesic effect of BV treatment using Freund's adjuvant induced chronic arthritis model. Freund's adjuvant-induced arthritis has been used as an experimental animal model for RA in humans to assess the efficacy of the anti-inflammatory/analgesic drugs. In this study, subcutaneous BV treatment (1mg/kg/day) produced significantly reductions of symptoms related to arthritic pain (i.e. mechanical hyperalgesia and thermal hyperalgesia). The anti-nociceptive effect of BV was observed from at least 12 days after BV treatment. Furthermore, BV treatment significantly suppressed adjuvant induced Fos expression in lumbar spinal cord. We also found that local injection of BV into near the inflammatory site (especially Zusanli-acupoint) showed more potent analgesic effect on arthritic pain rather than distant injection of BV from inflammatory site (arbitrary side of back). The present study demonstrates that BV treatment has anti-nociceptive effect on arthritis induced inflammatory pain. The analgesic effect of BV on RA is probably mediated by the effect of BV itself or possible other mechanism such as counter-irritation. Furthermore, it is possible that BV acupuncture is one of the promising candidates for long-term therapy of RA.

• Physical Therapy Rehabilitation Science
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• 제9권3호
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• pp.201-208
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• 2020

Objective: This study aimed to identify the effects of performing shoulder and hip abduction during the V-sit exercise on abdominal muscle activity. Design: Cross-sectional study. Methods: Thirty healthy adults volunteered for this experiment. The participants randomly performed 6 types of V-sit exercises, including V-sit alone (hip 0°, shoulder 0°), V-sit with hip abduction 0° and shoulder abduction 15°, V-sit with hip abduction 0° and shoulder abduction 30°, V-sit with hip abduction 15° and shoulder abduction 0°, V-sit with shoulder and hip abduction 15°, and V-sit with shoulder abduction 30° and hip abduction 15°. EMG data were recorded from the rectus abdominis (RA), external oblique (EO), and internal oblique (IO) muscles of both sides. All abdominal EMG data during the six types of V-sit exercises were measured for 5 seconds, three times, and recorded for the middle 3 seconds excluding the 1 second at the start and end. Results: V-sit with shoulder abduction 30° resulted in significantly greater muscle activity of both RA, EO compared to shoulder abduction 0°, shoulder abduction 15° (p<0.05) and V-sit with shoulder abduction 15° showed significantly greater muscle activation of the RA compared with shoulder abduction 0° (p<0.05). The muscle activity of both EO and IO in the V-sit with hip abduction 15° was significantly greater than hip abduction 0° in all shoulder conditions (p<0.05). Conclusions: Greater angles of shoulder and hip abduction produced more abdominal muscle activity increases during the V-sit exercises. Shoulder abduction affected the RA, EO muscle activation and hip abduction affected the EO, IO muscle activation. This study showed that shoulder and hip abduction during V-sit exercises enabled effective activation of the trunk muscles.