• Archives of Plastic Surgery
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• v.48 no.4
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• pp.353-360
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• 2021

Background Despite evidence supporting the safety of breast implants, some women associate their implants with adverse health effects and have called this syndrome "breast implant illness." We sought to characterize breast implant illness symptoms and to report how implant removal affects their symptoms. Methods An anonymous 20 question survey was administered to the Facebook group: "UTAH Breast Implant Illness" to characterize the symptoms these women attributed to their breast implants. Several questions allowed us to evaluate how implant removal affected women's symptoms. Results Of the 182 respondents, 97% report that implants negatively affect their health and 95% identify these symptoms with breast implant illness. Ninety-six percent of respondents had implants placed for cosmetic reasons and 51% had silicone implants. The most common symptoms associated with breast implant illness are brain fog (95%), fatigue (92%), joint pain (80%), and hair loss (74%). Sixty percent of respondents learned about breast implant illness from family/friends and/or social media platforms (56%), 40% of respondents had their implants removed, and 97% report relief of their symptoms post-removal (23% complete, 74% partial). Following explantation, there was a significant improvement in all but one reported symptom. An association was found between the number of symptoms reported prior to explantation and the number of symptoms resolving following explantation. Conclusions Breast implant illness is a syndrome characterized by fatigue, decreased focus, hair loss, and joint pain after the placement of breast implants. Nearly all patients report improvement of symptoms after implant removal. Significant efforts should be made to better understand breast implant illness and its etiology.

• Journal of Veterinary Science
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• v.21 no.1
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• pp.5.1-5.12
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• 2020

The major glycoproteins of bovine gammaherpesvirus 4 (BoHV-4) are gB, gH, gM, gL, and gp180 with gB, gH, and gp180 being the most glycosylated. These glycoproteins participate in cell binding while some act as neutralization targets. Glycosylation of these envelope proteins may be involved in virion protection against neutralization by antibodies. In infected cattle, BoHV-4 induces an immune response characterized by low neutralizing antibody levels or an absence of such antibodies. Therefore, virus seroneutralization in vitro cannot always be easily demonstrated. The aim of this study was to evaluate the neutralizing capacity of 2 Argentine BoHV-4 strains and to associate those findings with the gene expression profiles of the major envelope glycoproteins. Expression of genes coding for the envelope glycoproteins occurred earlier in cells infected with isolate 10/154 than in cells infected with strain 07/435, demonstrating a distinct difference between the strains. Differences in serological response can be attributed to differences in the expression of antigenic proteins or to post-translational modifications that mask neutralizing epitopes. Strain 07/435 induced significantly high titers of neutralizing antibodies in several animal species in addition to bovines. The most relevant serological differences were observed in adult animals. This is the first comprehensive analysis of the expression kinetics of genes coding for BoHV-4 glycoproteins in 2 Argentine strains (genotypes 1 and 2). The results further elucidate the BoHV-4 life cycle and may also help determine the genetic variability of the strains circulating in Argentina.

• Clinical and Experimental Pediatrics
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• v.65 no.1
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• pp.35-46
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• 2022

Background: The growing prevalence of overweight and/or obese children is an important public health problem in both developed and developing countries. Although the association of obesity between parents and their children is well known, its underlying mechanisms are not well established. Purpose: This meta-analysis examined parent-child (PC) relationships in obesity and identified factors such as world region and country income level that may influence this relationship. Methods: We identified all related studies published between January 1, 2015 and May 31, 2020 by conducting a literature search using the MeSH terms "obesity," "overweight," "body mass index," "parent," "child," "associate," and "relate" in the PubMed database in English. Results: The meta-analysis of 23 studies that reported an odds ratio (OR) for parent and child obesity associations found a significant association between parents and children who were overweight or obese (pooled OR, 1.97; 95% confidence interval, 1.85-2.10). A meta-regression analysis was used to examine the sources of interstudy heterogeneity. The association between parent and child obesity was higher in Asia than in Europe and the Middle East and higher in high-income countries than in middle-or low-income countries. In addition, a higher association between parent and child obesity was found when both parents were obese than when only the father or mother was obese. This study from multiple countries indicates a significant PC relationship in weight status that varies according to PC pair type, parent and child weight statuses, world region, and country income level. Conclusion: These results demonstrate that the risk of childhood obesity is greatly influenced by parental weight status and indicate that parents could play an important role in preventing child obesity.

• Analytical Science and Technology
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• v.35 no.4
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• pp.161-168
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• 2022

Wheat is rich in sources of fiber, oligosaccharides, and resistant starch, simple carbohydrates which may have a protective role against carcinoma. Additionally, Whole wheat/bran as well includes contains phytochemicals such as flavonoids, lignans, folate, phytosterols, phenolic acids, and tocols. The above phytochemicals suitable forms antioxidant and cholesterol-reducing activities. Phytoestrogens are regarded as especially essential in the preventative measures of hormonally dependent malignancies such as breast cancer (BC). In this study lowered BC risk has been associated with whole grain/bran consumption with an odds ratio (OR=0.24 and 95 %CI=0.10-0.56). Wheat/bran appears to have a reliable protective impact against BC. While intake of white bread has been associated with a high risk of BC (OR=2.63 and CI 95 %=1.07-6.48). Also, the E-Selectin (SELE) Single nucleotide polymorphisms (SNPs) rs5353 A/G and rs932307 C/T were investigated using the sanger sequences approach. There was a positive association between genotypes (rs5353 GG+AG) and (rs932307 TT+CT) with rate consumption of wheat-white/bread and these genotypes were more frequent in patients had BC in comparison with a significant difference (P=0.03) (P=0.01), respectively. The genotypes (GG+AG) frequency of the rs5353 polymorphism and (TT+CT) genotypes of the rs932307 polymorphism in the present study had a high risk of cancer with (OR=3.05), (OR=4.17) respectively. While these genotypes showed no significant association with the rate of whole grain consumption in patients and control. Therefore, the type of wheat may associate with increased incidence of disease-related with type of Polymorphism because some present genotypes of SNPs showed high (OR) which may refer to their positive associated with disease, the white wheat consumption may active the risky association between SNPs and BC.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.2
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• pp.312-334
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• 2023

In large-scale computing, cloud computing plays an important role by sharing globally-distributed resources. The evolution of cloud has taken place in the development of data centers and numerous servers across the globe. But the cloud information centers incur huge operational costs, consume high electricity and emit tons of dioxides. It is possible for the cloud suppliers to leverage their resources and decrease the consumption of energy through various methods such as dynamic consolidation of Virtual Machines (VMs), by keeping idle nodes in sleep mode and mistreatment of live migration. But the performance may get affected in case of harsh consolidation of VMs. So, it is a desired trait to have associate degree energy-performance exchange without compromising the quality of service while at the same time reducing the power consumption. This research article details a number of novel algorithms that dynamically consolidate the VMs in cloud information centers. The primary objective of the study is to leverage the computing resources to its best and reduce the energy consumption way behind the Service Level Agreement (SLA)drawbacks relevant to CPU load, RAM capacity and information measure. The proposed VM consolidation Algorithm (PVMCA) is contained of four algorithms: over loaded host detection algorithm, VM selection algorithm, VM placement algorithm, and under loading host detection algorithm. PVMCA is dynamic because it uses dynamic thresholds instead of static thresholds values, which makes it suggestion for real, unpredictable workloads common in cloud data centers. Also, the Algorithms are adaptive because it inevitably adjusts its behavior based on the studies of historical data of host resource utilization for any application with diverse workload patterns. Finally, the proposed algorithm is online because the algorithms are achieved run time and make an action in response to each request. The proposed algorithms' efficiency was validated through different simulations of extensive nature. The output analysis depicts the projected algorithms scaled back the energy consumption up to some considerable level besides ensuring proper SLA. On the basis of the project algorithms, the energy consumption got reduced by 22% while there was an improvement observed in SLA up to 80% compared to other benchmark algorithms.

• Journal of The Korean Association of Information Education
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• v.26 no.5
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• pp.467-480
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• 2022

This paper aimed to explore research trends for the conceptualization of IT humanities. Reflecting domestic and international references which focused on the possibility of the integration of digital technology and humanities, the authors examined the beginning, background, and relevant concepts of IT humanities to figure out the meaning and the research trends. In addition, using the search word "IT humanities," the authors analyzed network topics of the keywords retrieved from 1,566 KCI and 64 SCI journal articles published since 2001. The concept of IT humanities in the previous studies has tended to associate with competencies that allow considering various fields of IT based on the lens of humanities perspectives. The result of the topic modeling revealed four groups as fields to be integrated with IT humanities, methods of implementation, connections of literature or culture, and creations of IT humanities. Instead of instrumentalization or merger by one stance of IT or humanities, it is imperative to collaboratively work for the generation of a new viewpoint through mutual respect of disciplines.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1226-1236
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• 2022

Because students majoring in construction-related fields must develop a broad repository of knowledge and skills, effective transferal of these is the primary focus of most academic programs. While inculcation of this body of knowledge is certainly critical, actual construction projects are complicated ventures that involve levels of risk and uncertainty, such as resistant neighboring communities, unforeseen weather conditions, escalating material costs, labor shortages and strikes, accidents on jobsites, challenges with emerging forms of technology, etc. Learning how to develop a level of discernment about potential ways to handle such uncertainty often takes years of costly trial-and-error in the proverbial "school of hard knocks." There is therefore a need to proactively expedite the development of a sharpened intuition when making decisions. The AGC Education and Research Foundation case study committee was formed to address this need. Since its inception in 2011, 14 freely downloadable case studies have thus far been jointly developed by an academics and industry practitioners to help educators elicit varied responses from students about potential ways to respond when facing an actual project dilemma. AGC case studies are typically designed to focus on a particular concern and topics have thus far included: ethics, site logistics planning, financial management, prefabrication and modularization, safety, lean practices, preconstruction planning, subcontractor management, collaborative teamwork, sustainable construction, mobile technology, and building information modeling (BIM). This session will include an overview of the history and intent of the AGC case study program, as well as lively interactive demonstrations and discussions on how case studies can be used both by educators within a typical academic setting, as well as by industry practitioners seeking a novel tool for their in-house training programs.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.33 no.1
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• pp.345-369
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• 2022

The purpose of this study is to build a metadata set based on the semantic structure of the humanities field research articles for research data that can associate research data and research articles. To understand the interest of Humanities researchers, keywords of research articles were categorized. By proceeding the keywords classification and analyzing based on the semantic structure of general research papers, additional elements to be added were identified for reflecting the characteristics of the humanities field. Based on it, 17 metadata elements based on the semantic structure of research papers in the humanities field was determined. In order to evaluate whether the metadata is appropriate as a metadata for research data in the humanities field, a survey was conducted on researchers in the humanities field. As a result of the survey, 7 elements were judged to be suitable for use as metadata for research data in the field of humanities, and 10 other elements were identified as usable elements. Drawing on the survey results, the metadata based on the semantic structure of the humanities field research articles for research data was constructed.

• Animal Bioscience
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• v.36 no.9
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• pp.1357-1366
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• 2023

Objective: This study aimed to identify the single-nucleotide polymorphisms (SNPs) in the dual-specificity phosphatase 8 (DUSP8) and insulin-like growth factor 2 (IGF2) genes and to explore their effects on inosine-5'-monophosphate (IMP), inosine, and hypoxanthine contents in Korean native chicken -red-brown line (KNC-R Line). Methods: A total sample of 284 (males, n = 127; females n = 157) and 230 (males, n = 106; females, n = 124) aged of 10 weeks old KNC-R line was used for genotyping of DUSP8 and IGF2 genes, respectively. One SNP (rs313443014 C>T) in DUSP8 gene and two SNPs (rs315806609A/G and rs313810945T/C) in IGF2 gene were used for genotyping by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and KASP methods, respectively. The Two-way analysis of variance of the R program was used to associate DUSP8 and IGF2 genotypes with nucleotide contents in KNC-R chickens. Results: The DUSP8 (rs313443014 C>T) was polymorphic in KNC-R line and showed three genotypes: CC, CT, and TT. The IGF2 gene (rs315806609A/G and rs313810945T/C) was also polymorphic and had three genotypes per SNP, including GG, AG, and AA for the SNP rs315806609A/G and genotypes: CC, CT, and TT for the SNP rs313810945T/C. Association resulted into a strong significant association (p<0.01) with IMP, inosine, and hypoxanthine. Moreover, the significant effect of sex (p<0.05) on nucleotide content was also observed. Conclusion: The SNPs in the DUSP8 and IGF2 genes might be used as genetic markers in the selection and production of chickens with highly flavored meat.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.336-336
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• 2021

기후변화와 도시화로 인한 집중 호우와 불투수층 증가로 도시 홍수의 발생 빈도와 규모가 증가하고 있다. 인적, 물적 자원이 집중되어 있는 도시유역의 특성상 침수가 발생하면 이로 인한 직접적 피해 뿐만 아니라 사회경제적 2차 피해를 발생한다. 도시 홍수로 인한 피해를 줄이고 도시의 재해에 대한 회복력을 키우기 위해서는 관측과 더불어 정확한 모의 기술이 중요하다. 한편, 격자 기반 도시 홍수 모의는 집중 호우에 따른 침수의 시공간적 발생 양상을 물리적으로 해석하는 방법으로, 지표수-우수관거 이중배제 통합 모의, 수치기법, 병렬컴퓨팅, 수질 연계 모의 등의 측면에서 지금까지 많은 발전이 이루어져 왔다. 최근들어 원격탐사 기술의 발달로 공간해상도 1미터 수준 혹은 그 이상의 초고해상도 지형자료가 많은 지역에서 대해 가용해지고 있으며, 도시 홍수 해석에 이와 같은 초고해상도 자료를 적용하기 위한 연구가 활발히 진행되고 있다. 본 연구에서는 초고해상도 지형 및 토지 피복 자료의 공간해상도가 침수해석에 미치는 영향을 분석한다. 도시침수의 두가지 주요 요인인 내수침수와 외수범람 중에서 극한 강우에 의한 내수침수해석 사례만을 주요 연구 범위로 한다. 초고해상도 입력자료의 격자기반 도수 해석 모형으로는 운동파 기반의 2차원 지표 흐름 해석 모형을 적용하고, 초고해상도 모의의 효율적 계산을 위해 하이브리드 병렬 컴퓨팅 기술을 이용한다. 초고해상도 입력자료 적용 사례 대비, 공간해상도 저하에 따라 침수 면적이나 깊이 등에서 어떤 변화가 있는지 정량적으로 검토한다. 또한, 강우의 강도 및 공간분포가 초고해상도 도시 홍수 해석에 미치는 영향에 대해서 분석한다. 모의 결과로부터 도시 홍수 해석시 거리 단위(street-level) 정확도의 재현을 위해 적정한 공간해상도를 분석하고, 초고해상도 도시 홍수 모의를 이용한 기후변화에 따른 극한 홍수의 도시지역 영향 분석 및 회복력 개선 관련 연구의 가능성에 대해 논의한다.