• Journal of Environmental Health Sciences
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• v.28 no.2
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• pp.149-160
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• 2002

Analysis of benthic macroinvertebrate community structure and biological estimation of water quality by the benthic macroinvertebrates from the Mt. Myungji(1267m), Mt. Kalbong(840m), Mt. Daegeum(704m) and Mt. Jubal(489m) region of Gapyung-gun, Kyunggi-do were investigated from April to November, 2001. Total taxa of benthic macroinvertebrates were 105 species, 38 families, 13 orders, 5 classes in 4 phyla. Aquatic insects were 33 species in ephemeroptera, 5 species in odonata, 13 species in plecoptera, 2 species in hemiptera, 1 species in megaloptera, 27 species in trichoptera, 3 species in coleoptera and 13 species in diptera, respectively. Non-insects were 1 species in platyhelminthes, 5 species in gastropoda, 1 species in oligochaeta, 1 species in crustacea, respectively. Ephemeroptera, trichoptera and plecoptera as indicators in clean water were very abundantly. Occurrence species at each survey area was 67 species at Mt. Myungji and 69 species at Mt. Kalbong, 48 species at Mt. Daege.um and 47 species at Mt. Jubal, respectively. Mean species diversity indices at Mt. Myungji, Mt. Kalbong, Mt. Daegeum and Mt. Jubal were 3.30, 3.33, 2.59 and 3.43, respectively. According to the saprobic system based on the species diversity indices of benthic macroinvertebrates, Mt. Myungji, Mt. Kalbong and Mt. Jubal are determined as Limnosaprobic area, respectively, but Mt. Daegeum is determined as $\beta$-mesosaprobic area.

• Journal of environmental and Sanitary engineering
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• v.18 no.2
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• pp.16-26
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• 2003

Analysis of benthic macroinvertebrate community and biological estimation of water quality was conducted at the national park of Mt. Jiri and its nearby area in Gurye, Sancheong and Hadong-gun from June to November, 2002. Total taxa of benthic macroinvertebrates were 124 species, 45 families, 15 orders, 5 classes in 3 phyla. Aquatic insects were 33 species in ephemeroptera, 28 species in Trichoptera, 21 species in plecoptera, 13 species in Diptera, 8 species in odonata, 5 species in hemiptera and 5 species in coleoptera, respectively. Non-insects were 5 species in Mollusca, 2 species in Hirudinea, 1 species in oligochaeta and 1 species in crustacea, respectively. Ephemeroptera, trichoptera and plecoptera as indicators in clean water were very abundant. Occurrence species at each survey area was 68 species at Mt. 1025-goji, 59 species at Mt. Eungseok-bong, 57 species at Mt. Wangdeung-jae, 50 species at Mt. Cheonwang-bong and 39 species at Mt. 645-goji, respectively. Mean species diversity indices at Mt. Cheonwang-bong, Mt. 1025-goji, Mt. Wangdeung-jae, Mt. Eungseok-bong and Mt. 645-goji were 3.33, 3.03, 3.41, 3.02 and 2.91, respectively, According to the saprobic system based on the species diversity indices of benthic macroinvertebrates, most survey areas except some sites are determined as Limnosaprobic area.

• Environmental Analysis Health and Toxicology
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• v.12 no.3_4
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• pp.15-22
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• 1997

This experiment was performed to examine the immuno-reactive characteristics of fish metal-binding protein, metallothionein (MT), and gain the practical understandings for the proposed use of fish MT as a biomarker. Liver MT induced by Cd in the silver carp was seperated and purified by gel filtration chromatography and ion exchange chromatography. The immuno-reactivity of fish MT was examined with 3 rabbit antisera. Fish MT showed little reactivity with rabbit anti-rat MT antiserum and a weak reactivity with anti-MT peptide antiserum while showed a strong reactivity with rabbit anti-fish MT antiserum. The time-course change of liver MT in the silver carp, after waterborne exposure to 1 ppm of Cd, was checked by Cd-hem method and established competitive ELISA. In both cases, the induction of liver MT showed a good increasing relationship with the exposure days. The results indicate that the fish MT can be developed as a useful biomonitoring means in the toxicological study and for the evaluation of water pollution.

• Journal of The Korean Society of Grassland and Forage Science
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• v.23 no.3
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• pp.143-150
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• 2003

This study was conducted to determine the response of main growth characters, yield and chemical composition of Jeju native soybean based on the difference between phosphate rates (0, 50, 100, 150, 200, 250kg/ha) from May 11 to September 10 in 2002 in Jeju island. Days to flowering was delayed from 92 days to 97 days as the increasing of phosphate rate. Also plant height grew longer from 109cm to 124cm. The number of branches and leaves, stem diameter, root length and weight of root grew powerful as phosphate rate increased from 0 to 250kg/ha. Fresh forage yield was 26.5MT/ha in the nonphosphate plot and then was 36.9MT/ha as phosphate rate increased to 250kg/ha. And the difference between 200kg/ha and 250kg/ha in phosphate rate was not significant. Dry matter, crude protein and TDN yield increased 6.0∼7.9MT/ha, 0.9∼1.4MT/ha and 3.4∼4.9MT/ha respectively, as the increasing of phosphate rate. Also crude protein, crude fat, NFE and TDN content increased 15.5∼18.3%, 2.2∼3.3%, 42.5∼43.5%, and 56.7∼61.9% respectively. In contrast with this, crude fiber and crude ash decreased 32.1∼28.1% and 7.7∼6.8% respectively. To reach the climax of forage yield was estimated optimum phosphate rate to be 200kg/ha.

• Journal of environmental and Sanitary engineering
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• v.16 no.3
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• pp.62-71
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• 2001

The present study was performed to examine the community structure of benthic macroinvertebrates in the provincial park of Mt. Daedun and its nearby region. Sampling was conducted two times in May.June and October.November, 2000. Main two areas are Mt. Anpyong (470.0m) and Mt. Daedun (877.0m) area. Total taxa of benthic macroinvertebrates were 111 species, 47 families, 15 orders, 6 classes in 4 phyla. Aquatic insects were composed of 29 species in ephemeroptera, 10 species in odonata, 7 species in plecoptera, 2 species in hemiptera, 2 species in megaloptera, 23 species trichuptera, 6 species in coleoptera and 17 species in diptera. Other non-insects were composed of 1 species in platyhelminthes, 8 species in gastropoda, 2 species in oligochaeta, 3 species in hirudinea and 1 species in crustacea. Ephemeroptera, trichoptera and plecoptera as indicators in clean water were very abundantly. Occurrence species at each surrey area was 77 species at Mt. Anpyong area and 89 species at Mt. Daedun area, respectively. Mean values of species diversity indices were 3.04 and 2.69, respectively. According to the saprobic system based on the species diversity indices of benthic macroinvertebrates, Mt. Anpyong region are determined as polysaprobic area or ${\beta}-mesosaprobic$ area and Mt. Daedun region are determined as polysaprobic area, $\beta-mesosaprobic$ area or ${\alpha}-mesosaprobic$ area.

• Journal of Ginseng Research
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• v.44 no.2
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• pp.300-307
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• 2020

Background: Emerging evidence suggests that endothelial-to-mesenchymal transition (EndMT) in endothelial dysfunction due to persistent inflammation is a key component and emerging concept in the pathogenesis of vascular diseases. Ginsenoside Rg3 (Rg3), an active compound from red ginseng, has been known to be important for vascular homeostasis. However, the effect of Rg3 on inflammation-induced EndMT has never been reported. Here, we hypothesize that Rg3 might reverse the inflammation-induced EndMT and serve as a novel therapeutic strategy for vascular diseases. Methods: EndMT was examined under an inflammatory condition mediated by the NOD1 agonist, γ-d-glutamyl-meso-diaminopimelic acid (iE-DAP), treatment in human umbilical vein endothelial cells. The expression of EndMT markers was determined by Western blot analysis, real-time polymerase chain reaction, and immunocytochemistry. The underlying mechanisms of Rg3-mediated EndMT regulation were investigated by modulating the microRNA expression. Results: The NOD1 agonist, iE-DAP, led to a fibroblast-like morphology change with a decrease in the expression of endothelial markers and an increase in the expression of the mesenchymal marker, namely EndMT. On the other hand, Rg3 markedly attenuated the iE-DAP-induced EndMT and preserved the endothelial phenotype. Mechanically, miR-139 was downregulated in cells with iE-DAP-induced EndMT and partly reversed in response to Rg3 via the regulation of NF-κB signaling, suggesting that the Rg3-miR-139-5p-NF-κB axis is a key mediator in iE-DAP-induced EndMT. Conclusion: These results suggest, for the first time, that Rg3 can be used to inhibit inflammation-induced EndMT and may be a novel therapeutic option against EndMT-associated vascular diseases.

• Korean Journal of Remote Sensing
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• v.30 no.3
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• pp.341-350
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• 2014

Landsat images can monitor the snow-covered Earth surface variations with the ground resolution of 30m and the multi-spectral bands in the visible, NIR, SWIR and TIR spectral regions for the last 30 years. The Southern Volcanic Zone (SVZ) of Chile consists of many volcanoes, and all of the volcanoes are covered with snow at the top of mountain. Snow cover area in southern province of the SVZ of Chile (37 to $46^{\circ}S$) have been influenced by significant frontal retreats as well as eruptive activities. In this study, we have investigated the changes of the snow-cover area and snow-line elevation at Mt. Villarrica and Mt. Llaima, Chile from three Landsat images acquired on Feb. 1990, 2005 and 2011. The snow-cover areas are 13.42, 26.75 and $21.60km^2$ at Mt. Villarrica in 1990, 2005 and 2011, respectively, and 3.82, 25.12 and $8.89km^2$ at Mt. Llaima in 1990, 2005 and 2011, respectively. The snow-line elevations are 1871, 1738 and 1826m at Mt. Villarrica in 1990, 2005 and 2011, respectively, and 2007, 1822 and 1818m at Mt. Llaima in 1990, 2005 and 2011, respectively. The results indicate that both of the snow-cover and snow-line changes are strongly related with the volcanic activity change. The results demonstrate that the snow-cover area and snow-line elevation changes can be used as an indicator of the volcanic activity at Mt. Villarrica and Mt. Llaima, Chile.

• Journal of Pharmaceutical Investigation
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• v.23 no.3
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• pp.9-18
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• 1993

Sugar spheres loaded with melatonin (MT) were coated with $Aquacoat^{\circledR}$ to control the release rate of MT over 8 hours. A zero-order release pattern over 8 hours was obtained with 20% coating on 8-10 mesh beads in USP basket dissolution studies. MT in 20% coated beads was quite stable at room temperature with less than 5% MT degraded during 6 months' storage. Dissolution profiles were also unchanged after 6 months. An oral preparation containing MT-loaded uncoated beads for immediate release and 20% coated beads with $Aquacoat^{\circledR}$ for controlled release over 8 hours was evaluated in six human subjects. When total 0.5 mg MT as low dose (immediate release portion of MT, 0.1 mg) was administered to four subjects, average peak plasma MT concentration was reached at about 600 pg/ml and maintained at about 10 pg/ml over 8 hours. Plasma MT concentration-time profiles were similar in shape to computer-simulated profiles. However, maximal plasma MT concentrations were three times greater compared to computer simulated curve. These results suggest that MT dose, ratio of immediate and controlled release MT, and pharmacokinetic parameters selected are adjusted to mimic endogenous MT concentration-time curve. In another study, 0.2 mg MT having 10% of immediate release portion and 80% controlled release portion produced plasma MT concentration-time curve which is more similar to endogenous profiles. A low bioavailability (<20%) may result from extensive first pass metabolism and remaining amounts of MT from controlled beads. A good correlation between plasma MT concentration and urinary excretion rate of 6-sulphatoxymelatonin (6-STMT), a major metabolite of MT was observed. As plasma MT concentration increased, urinary excretion rate of 6-STMT increased concomitantly. The linear relation between plasma MT and urinary excretion rate of 6-STMT was statistically significant. This result suggests that urinary 6-STMT may be used as an index of circadian rhythms of MT in humans.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.46 no.6
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• pp.439-442
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• 2001

This study has been conducted from April 25, 1999 to June 25, 1999 in Jeju Province in order to determine the influence of seeding date on growth, yield and chemical composition of Kenaf (Hibiscus cannabinus L.) Delaying the seeding date from April 25 to June 25 decreased the plant height of Kenaf from 278.5 cm to 205.7 cm. As for the number of leaves, number of withering leaves, number of branches, and stem diameter decreased as the seeding date was delayed. As the seeding date was delayed, fresh forage yield decreased from 98.5MT/㏊ to 45.9MT/㏊, dry matter yield from 20.7MT/㏊ to 8.2MT/㏊, crude protein (CP) yield from 2.9MT/ha to 1.3MT/ha and total digestible nutrients (TDN) yield form 1l.6MT/㏊ to 5MT/㏊. However, both leaf yield and stem yield were nearly the same tendency. Delaying the seeding date from April 25 to June 25 increased crude protein contents of leaves from 21.5％ to 24.4％, crude fat contents from 5.2％ to 6.1％, nitrogen free extract (NFE) contents form 39.9％ to 41.2％ and TDN contents from 64.3％ to 69.7％. However, delaying seeding date decreased crude fiber contents from 20.8％ to 17.5％, and crude ash contents from 7.9％ to 7.0％. Based on the these findings, optimum seeding date for forage production of Kenaf seems to be about 25 April in atmospheric phenomena and volcanic ash soils of Jeju island.

• The Korean Journal of Ecology
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• v.10 no.3
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• pp.109-118
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• 1987

The production and decomposition rates of litters were studied in three mountains, Mt. Halla, Mt. So-back and Mt. Tae-back. The amounts of N, P, K, Ca and Na in the soils were measured and the relationships between the mineral nutrients and decay rates were reserched, The annual litter production was the most as $1, 077.3g/m^2$ and the least as $248.0g/m^2$ in a stand of Quercus acutissima at 820m of the Mt. So-back and at 1, 350m of the Mt. So-back among the study sites, respectively. The decay rates of litter was the highest as k=0.448 and the lowest as k=0.082 in a stand of Q. acutissima at 820m of the Mt. So-back and at 1, 450m of the Mt. Tae-back at 1, 450m of the Mt. Tae-back among the study sites. The higher altitude was, the slower the decay rates were. The annual contents of mineral nutrient and their amounts inputted into the forest soil were proportional to the decay rate of organic metters.