• Journal of the Korea Concrete Institute
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• v.21 no.2
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• pp.179-186
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• 2009

The peculiarity pointed out for high strength concrete is the occurrence of spalling during a fire. Recently, there are many efforts such as development of all types of spalling reducing materials and other innovative materials in various fields. Need is now to examine the adequate mixing proportions of these materials. This study intended to derive experimentally and statistically mix proportions that can represent the basic quality requirements as well as the optimal effects on the fire-resistance for 4 types of functional materials that are metakaolin, waste tire chip, polypropylene fiber and steel fiber. Here, the tests were planned through an optimal test method using an orthogonal array table with 4 parameters and 3 levels. The statistical analysis adopted the response surface analysis method. Results verified mutual complementary contribution between the materials when using a combination of the functional materials selected as parameters for the strengthening of the fire-resistance of 80 MPa-class high strength concrete. Besides, the optimal conditions of the fire-resistance strengthening materials derived through response surface analysis were a volumetric replacement of silica fume by 80% of metakaolin, a volumetric replacement of fine aggregates by 3% of tire waste chip, and an addition of 0.2% of the whole volume by polypropylene fiber without mixing of steel fiber. In such cases, the basic characteristics as well as the fire-resistant characteristics of high strength concrete were also satisfied.

• Journal of the Microelectronics and Packaging Society
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• v.12 no.3 s.36
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• pp.243-251
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• 2005

The distribution of temperature of flip chipped device with peripheral solder bump array was measured with variables, such as the locations and geometries of heater, the size of device, the size of passivation opening. The highest temperature was measured with the larger device, $3.0(mm)\times3.0(mm)$, which has the smallest heater at the center of device and the circular passivation opening. For 2 (watts) power input, the device shows the highest temperature of about $110(^{\circ}C)$. In contrast, the smaller device, $1.5(mm)\times1.8(mm)$, shows that of $90(^{\circ}C)$. In addition to the size effect, the increase of passivation opening size decreased the maximum temperature by about $10(^{\circ}C)$. From the measurement, the temperature of device could be controlled with the size and geometry of heater, the size of device and the size and geometry of passivation opening.

• Journal of the Microelectronics and Packaging Society
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• v.22 no.3
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• pp.9-17
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• 2015

After its inception in 1994, the Journal of the Microelectronics and Packaging Society has continued to make significant strides in the number and quality of publications within its field. The interest in the microelectronics and packaging research has become more critical as consumer electronic products continue its increasing trend towards thinner and lighter devices that tests the boundaries of electronic devices. This study utilizes social network analysis of all published literature in the Journal for the past 22 years. Using the keywords and abstracts available within each individual article, the publications within the Journal has focused on major topics covering (1) flip chip, (2) reliability, (3) Cu, (4) IMC (intermetallic compounds), and (5) thin film. Using the social network relationship between keywords within articles, flip chip was closely associated with reliability, BGA (ball grid array), contact resistance, electromigration in many of the published research works within the Journal. From the centrality analysis, it was found that flip chip, reliability, Cu, thin film, IMC, and RF (radio frequency) to have a high degree of centrality suggesting these key areas of research have relatively high connectivity with other research topics within the Journal and is central to many of the research fields within the micro-electronics and packaging area. The cohesiveness analysis showed research clustering of five major cohesive sub-groups and was mapped to better understand the major area of research within this field. Research within the field of micro-electronics and packaging converges many disciplines of science and engineering. The continued evolution within this field requires an understanding of the rapidly changing industry environment and the consumer needs.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2519-2525
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• 2016

There are several existing reports of microarray chip use for assessment of altered gene expression in different diseases. In fact, there have been over 1.5 million assays of this kind performed over the last twenty years, which have influenced clinical and translational research studies. The most commonly used DNA microarray platforms are Affymetrix GeneChip and Quality Control Software along with their GeneChip Probe Arrays. These chips are created using several quality controls to confirm the success of each assay, but their actual impact on gene expression profiles had not been previously analyzed until the appearance of several bioinformatics tools for this purpose. We here performed a data mining analysis, in this case specifically focused on ovarian cancer, as well as healthy ovarian tissue and ovarian cell lines, in order to confirm quality control results and associated variation in gene expression profiles. The microarray data used in our research were downloaded from ArrayExpress and Gene Expression Omnibus (GEO) and analyzed with Expression Console Software using RMA, MAS5 and Plier algorithms. The gene expression profiles were obtained using Partek Genomics Suite v6.6 and data were visualized using principal component analysis, heat map, and Venn diagrams. Microarray quality control analysis showed that roughly 40% of the microarray files were false negative, demonstrating over- and under-estimation of expressed genes. Additionally, we confirmed the results performing second analysis using independent samples. About 70% of the significant expressed genes were correlated in both analyses. These results demonstrate the importance of appropriate microarray processing to obtain a reliable gene expression profile.

• Journal of Animal Reproduction and Biotechnology
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• v.39 no.2
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• pp.138-144
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• 2024

Background: As the number of households raising companion dogs increases, the pet genetic analysis market also continues to grow. However, most studies have focused on specific purposes or native breeds. This study aimed to collect genomic data through single nucleotide polymorphism (SNP) chip analysis of companion dogs in South Korea and perform genetic diversity analysis and SNP annotation. Methods: We collected samples from 95 dogs belonging to 26 breeds, including mixed breeds, in South Korea. The SNP genotypes were obtained for each sample using an Axiom^TM Canine HD Array. Quality control (QC) was performed to enhance the accuracy of the analysis. A genetic diversity analysis was performed for each SNP. Results: QC initially selected SNPs, and after excluding non-diverse ones, 621,672 SNPs were identified. Genetic diversity analysis revealed minor allele frequencies, polymorphism information content, expected heterozygosity, and observed heterozygosity values of 0.220, 0.244, 0.301, and 0.261, respectively. The SNP annotation indicated that most variations had an uncertain or minimal impact on gene function. However, approximately 16,000 non-synonymous SNPs (nsSNPs) have been found to significantly alter gene function or affect exons by changing translated amino acids. Conclusions: This study obtained data on SNP genetic diversity and functional SNPs in companion dogs raised in South Korea. The results suggest that establishing an SNP set for individual identification could enable a gene-based registration system. Furthermore, identifying and researching nsSNPs related to behavior and diseases could improve dog care and prevent abandonment.

• Journal of the Korea Convergence Society
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• v.8 no.5
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• pp.161-167
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• 2017

We have fabricated and characterized $32{\times}32$ photonic quantum ring (PQR) laser arrays uniformly operable with $0.98{\mu}A$ per ring at room temperature. The typical threshold current, threshold current density, and threshold voltage are 20 mA, $0.068A/cm^2$, and 1.38 V. The top surface emitting PQR array contains GaAs multiquantum well active regions and exhibits uniform characteristics for a chip of $1.65{\times}1.65mm^2$. The peak power wavelength is $858.8{\pm}0.35nm$, the relative intensity is $0.3{\pm}0.2$, and the linewidth is $0.2{\pm}0.07nm$. We also report the wavelength division multiplexing system experiment using angle-dependent blue shift characteristics of this laser array. This photonic quantum ring laser has angle-dependent multiple-wavelength radial emission characteristics over about 10 nm tuning range generated from array devices. The array exhibits a free space detection as far as 6 m with a function of the distance.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.7
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• pp.678-685
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• 2013

In this paper, we propose a design of dual-band patch antennas for Global Positioning System(GPS) applications, and the designed antenna is used as an individual element of GPS arrays. A low distortion and a high isolation of the array are achieved by adjusting rotating angles of each array element. The antenna consists of two radiating patches that operate in the GPS $L_1$ and $L_2$ bands, and the two ports feeding network with a hybrid chip coupler is adopted to achieve a broad circular polarization(CP) bandwidth. The rotating angles of each antenna element are varied with four directions(${\phi}=0^{\circ}$, ${\phi}=90^{\circ}$, ${\phi}=180^{\circ}$, ${\phi}=270^{\circ}$) in order to minimize the pattern distortion and maximize the isolation among array elements. The measurement shows bore-sight gains of 0.3 dBic($L_1$) and -1.0 dBic($L_2$) for the center element. Bore-sight gains of 1.6 dBic($L_1$) and 1.0 dBic($L_2$) are observed for the edge element. This results demonstrate that the proposed antenna is suitable for GPS array applications.

• Genomics & Informatics
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• v.6 no.4
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• pp.231-234
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• 2008

Precise and reliable identification of CNV is still important to fully understand the effect of CNV on genetic diversity and background of complex diseases. SNP marker has been used frequently to detect CNVs, but the analysis of SNP chip data for identifying CNV has not been well established. We compared various normalization methods for CNV analysis and suggest optimal normalization procedure for reliable CNV call. Four normal Koreans and NA10851 HapMap male samples were genotyped using Affymetrix Genome-Wide Human SNP array 5.0. We evaluated the effect of median and quantile normalization to find the optimal normalization for CNV detection based on SNP array data. We also explored the effect of Robust Multichip Average (RMA) background correction for each normalization process. In total, the following 4 combinations of normalization were tried: 1) Median normalization without RMA background correction, 2) Quantile normalization without RMA background correction, 3) Median normalization with RMA background correction, and 4) Quantile normalization with RMA background correction. CNV was called using SW-ARRAY algorithm. We applied 4 different combinations of normalization and compared the effect using intensity ratio profile, box plot, and MA plot. When we applied median and quantile normalizations without RMA background correction, both methods showed similar normalization effect and the final CNV calls were also similar in terms of number and size. In both median and quantile normalizations, RMA backgroundcorrection resulted in widening the range of intensity ratio distribution, which may suggest that RMA background correction may help to detect more CNVs compared to no correction.

• The Journal of the Acoustical Society of Korea
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• v.30 no.3
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• pp.115-122
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• 2011

In this paper, we present a method to estimate an accurate real-time sound source direction based on time delay of arrival by using generalized cross correlation with four cross-type microphones. In general, existing systems have two disadvantages such as system embedding limitation due to the necessity of data acquisition for signal processing from microphone input, and real-time processing difficulty because of the increased number of channels for sound direction estimation using DSP processors. To cope with these disadvantages, the system considered in this paper proposes hardware design for enhanced real-time processing using microphone array signal processing. An accurate direction estimation and its design time reduction is achieved by means of an efficient hardware design using spatial segmentation methods and verification techniques. Finally we develop a system which can be used for embedded systems using a sound codec and an FPGA chip. According to experimental results, the system gives much faster real-time processing time compared with either PC-based systems or the case with DSP processors.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.5
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• pp.355-365
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• 2017

In this paper, we propose the design of a dual-band GPS antenna using in-direct feeding pads. The antenna consists of an upper patch for the GPS L1 band, a lower patch for the GPS L2 band, and two pads on the middle layer for feeding the two radiating patches. A hybrid chip coupler with a phase difference of $90^{\circ}$ is employed at the two feeding ports for achieving a broad circular polarization (CP) bandwidth. The proposed antenna shows bore-sight gains of 3.0 dBic(L1) and 5.1 dBic(L2), and axial ratios of 3.3 dB(L1) and 0.3 dB(L2) by measurement. The active element patterns of the fabricated array with 7 elements show bore-sight gains of -0.4 dBic (L1) and -2.4 dBic(L2), respectively. It proves that the proposed antenna structure is suitable for use in GPS array applications.