• Proceedings of the Korea Environmental Mutagen Society Conference
• /
• 2002.11a
• /
• pp.158-158
• /
• 2002

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2002.11b
• /
• pp.158-158
• /
• 2002

The potential toxicological effects of aristolochic acid (AA), a natural component in Aristolochiaceae family, were investigated. The 13-week toxicity study consisted of groups of 10 SD rat/sex administrated water containing 0, 0.05, 0.5, or 5 mg/kg per day AA (Study 1). The tested groups were terminated on Test Day 90 due to mortality and overt clinical signs of toxicity.(omitted)