• Title/Summary/Keyword: Application of Safety Knowledge

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The Effectiveness of 448-kHz Capacitive Resistive Monopolar Radiofrequency for Subcutaneous Fat Reduction in a Porcine Model

  • Kwon, Tae-Rin;Lee, Sung-Eun;Kim, Jong Hwan;Jeon, Yong Jae;Jang, You Na;Yoo, Kwang Ho;Kim, Beom Joon
    • Medical Lasers
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    • v.8 no.2
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    • pp.64-73
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    • 2019
  • Background and Objectives The effectiveness of many physiotherapy modalities in reducing subcutaneous fat has been investigated in numerous previous studies. However, to the best of our knowledge, there have been no attempts to determine the effectiveness of physiotherapy modalities in body contouring. The present report determined the effect of 448-kHz capacitive resistive monopolar radiofrequency (CRMRF) in a porcine model. Materials and Methods This study investigated the effect of selective destruction of the subcutaneous fat layer in abdominal fat tissue using CRMRF. The effects of two types of CRMRF (capacitive electric transfer (CET) and resistive electric transfer (RET)) treatment were evaluated using regular digital photography in addition to thermal imaging evaluation, ultrasound measurement, hematological evaluation, and histologic analyses (H&E (hematoxylin and eosin), Oil red O, and immunohistochemistry staining). Results Preclinical evaluation was performed to obtain the data for comparison of the safety and efficacy of the subcutaneous fat reduction after applying CRMRF using CET and RET. After treatment, the thermal transmission was effective, and a 42-47℃ temperature change was observed in the fat layer while an approximately temperature of 42℃ was confirmed on the skin surface. Moreover, after the application of both types of CRMRF treatment, fibrotic septa were observed in the adipose tissue induced by heat at the treatment sites. TUNEL staining was also performed to confirm the process of apoptosis in the adipocytes. Conclusion These results suggest that both CET and RET for CRMRF treatment are safe and effective for subcutaneous fat reduction in a porcine model.

Traditional Foods: Historical Perspectives and Future Prospects (문화와 과학의 융합적 관점에서 본 전통음식의 역사 및 미래)

  • Kim, Hee Sup
    • Journal of the Korean Society of Food Culture
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    • v.30 no.1
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    • pp.1-7
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    • 2015
  • Traditional cuisine reflects cooking traditions shaped by political, economic, social, cultural, and environmental conditions characterized by authenticity and uniqueness. Traditional food is not only a part of our cultural heritage but also a knowledge resource. Application of food science and technology in Korean traditional foods was reviewed from six points of view, including food preservation, fermentation, changes in food materials, utilization of food functionality, and packaging and development of cooking appliances. Books from disparate times were chosen in order to cover a wide range of materials from the past to the present. Food preservation and fermentation techniques were applied to various food materials. Combination of science and skills contributes to the accessibility of diverse food materials and better quality foods. Koreans use assorted and resilient plants, which have an abundance of functional substances such as food materials. Among cooking appliances, microwave oven and refrigerator are the most innovative products with huge influences on food eating patterns as well as lifestyle. Packaging effectively reduces post-harvest preservation losses, and better packaging has technical improvements for storage and distribution. Kimchi was chosen as an example in order to study technology from the past to the present. Availability of Kimchi cabbage, enrichment of functional ingredients, identification of useful microbial species, standardization of recipe for commercialization, prevention of texture softening, introduction of salted Kimchi cabbage and Kimchi refrigerators, and packaging were reviewed. The future of traditional foods in the market will be competitive. First, traditional foods market should be maintained to protect the diversity of food materials. Secondly, tailored foods for individuals should be considered using foods with functional properties. Information on health benefits would provide insights into health and traditional food products. Third, speedy transfer of new technology to the traditional food industry is needed to ensure food quality production and new opportunities in the market. Fourth, safety of traditional foods should be ensured without sacrificing the essential characteristics of culturally important foods. Improvement of logistics, distribution, and facility should be carried out. As demand for convenience foods increases, traditional foods should be developed into products.

Potential Roles of Essential Oils on Controlling Plant Pathogenic Bacteria Xanthomonas Species: A Review

  • Bajpai, Vivek K.;Kang, So-Ra;Xu, Houjuan;Lee, Soon-Gu;Baek, Kwang-Hyun;Kang, Sun-Chul
    • The Plant Pathology Journal
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    • v.27 no.3
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    • pp.207-224
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    • 2011
  • Diseases caused by plant pathogenic bacteria constitute an emerging threat to global food security. Xanthomonas is a large genus of Gram-negative bacteria that cause disease in several host plants leading to considerable losses in productivity and quality of harvests. Despite the ranges of controlling techniques available, the microbiological safety of economically important crops and crop plants including fruits and vegetables continues to be a major concern to the agriculture industry. On the other hand, many of the currently available antimicrobial agents for agriculture are highly toxic, non-biodegradable and cause extended environmental pollution. Besides, the use of antibiotics has provoked an increased resistance among the bacterial pathogens and their pathovars. Thus, novel efficient and safe remedies for controlling plant bacterial diseases are necessary. There has been an increasing interest worldwide on therapeutic values of natural products such as essential oils, hence the purpose of this review is to provide an overview of the published data on the antibacterial efficacy of essential oils that could be considered suitable for application in agriculture as biocontrol measures against plant pathogenic bacteria of Xanthomonas species. The current knowledge on the use of essential oils to control Xanthomonas bacteria in vitro and in vivo models has been discussed. A brief description on the legal aspects on the use of essential oils against bacterial pathogens has also been presented. Through this review, a mode of antibacterial action of essential oils along with their chemical nature and the area for future research have been thoroughly discussed.

Introduction of Korea Oil Identification System(KOIS) (우리나라의 해상유출물질 감식.분석기법 연구)

  • Lee, Y.S.;Lee, S.J.;Kim, C.S.;Oh, H.J.;Kim, H.G.
    • Proceedings of KOSOMES biannual meeting
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    • 2006.05a
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    • pp.85-92
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    • 2006
  • Crude oil is complex mixture if thousands of different organic compound formed from a variety of organic materials that are chemically converted under differing geological conditions over long periods of time. Also oil composition varies according to crude source, refining, processing, handling and storage. The oil fingerprint method is application if specific knowledge of petrochemicals and use if sophisticated analytical equipment and techniques to identify the source(s) if oil pollution. KCG currently utilizes four primary analytical techniques: Gas Chromatography (GC), Fluorescence Spectroscopy(FL), Infrared Spectroscopy(IR) and Gas Chromatography mass spectrometer(GC/MS). Of all these techniques, GC technique are most widely used Gas Chromatography is used as a primary analytical method because high reliableness, high separating efficiency and repeatability.

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CHAINED COMPUTATIONS USING AN UNSTEADY 3D APPROACH FOR THE DETERMINATION OF THERMAL FATIGUE IN A T-JUNCTION OF A PWR NUCLEAR PLANT

  • Pasutto, Thomas;PENiguel, Christophe;Sakiz, Marc
    • Nuclear Engineering and Technology
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    • v.38 no.2
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    • pp.147-154
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    • 2006
  • Thermal fatigue of the coolant circuits of PWR plants is a major issue for nuclear safety. The problem is especially accute in mixing zones, like T-junctions, where large differences in water temperature between the two inlets and high levels of turbulence can lead to large temperature fluctuations at the wall. Until recently, studies on the matter had been tackled at EDF using steady methods: the fluid flow was solved with a CFD code using an averaged turbulence model, which led to the knowledge of the mean temperature and temperature variance at each point of the wall. But, being based on averaged quantities, this method could not reproduce the unsteady and 3D effects of the problem, like phase lag in temperature oscillations between two points, which can generate important stresses. Benefiting from advances in computer power and turbulence modelling, a new methodology is now applied, that allows to take these effects into account. The CFD tool Code_Saturne, developped at EDF, is used to solve the fluid flow using an unsteady L.E.S. approach. It is coupled with the thermal code Syrthes, which propagates the temperature fluctuations into the wall thickness. The instantaneous temperature field inside the wall can then be extracted and used for structure mechanics computations (mainly with EDF thermomechanics tool Code_Aster). The purpose of this paper is to present the application of this methodology to the simulation of a straight T-junction mock-up, similar to the Residual Heat Remover (RHR) junction found in N4 type PWR nuclear plants, and designed to study thermal striping and cracks propagation. The results are generally in good agreement with the measurements; yet, in certain areas of the flow, progress is still needed in L.E.S. modelling and in the treatment of instantaneous heat transfer at the wall.

Design of Fuzzy Model-based Multi-objective Controller and Its Application to MAGLEV ATO system (퍼지 모델 기반 다목적 제어기의 설계와 자기부상열차 자동운전시스템에의 적용)

  • 강동오;양세현;변증남
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.10a
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    • pp.211-217
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    • 1998
  • Many practical control problems for the complex, uncertain or large-scale plants, need to simultaneously achieve a number of objectives, which may conflict or compete with each other. If the conventional optimization methods are applied to solve these control problems, the solution process may be time-consuming and the resulting solution would ofter lose its original meaning of optimality. Nevertheless, the human operators usually performs satisfactory results based on their qualitative and heuristic knowledge. In this paper, we investigate the control strategies of the human operators, and propose a fuzzy model-based multi-objective satisfactory controller. We also apply it to the automatic train operation(ATO) system for the magnetically levitated vehicles(MAGLEV). One of the human operator's strategies is to predict the control result in order to find the meaningful solution. In this paper, Takagi-Sugeno fuzzy model is used to simulated the prediction procedure. Another str tegy is to evaluate the multiple objectives with respect to their own standards. To realize this strategy, we propose the concept of a satisfactory solution and a satisfactory control scheme. The MAGLEV train is a typical example of the uncertain, complex and large-scale plants. Moreover, the ATO system has to satisfy multiple objectives, such as seed pattern tracking, stop gap accuracy, safety and riding comfort. In this paper, the speed pattern tracking controller and the automatic stop controller of the ATO system is designed based on the proposed control scheme. The effectiveness of the ATO system based on the proposed scheme is shown by the experiments with a rotary test bed and a real MAGLEV train.

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Clinical Use of Mesenchymal Stem Cells in Bone Regeneration (중간엽 줄기세포를 이용한 골재생의 임상적 활용)

  • Park, Chan-Woo;Lim, Seung-Jae;Park, Youn-Soo
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.6
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    • pp.490-497
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    • 2019
  • Owing to the recent advances in biological knowledge on stem cells, many efforts are being made to apply them to clinical practice. Although mesenchymal stem cells were first found in bone marrow aspirates, they are understood to be multipotent stromal cells that can be extracted from a variety of tissues, such as adipose, dermal, skeletal muscle, and umbilical-cord tissues. The osteogenicity of mesenchymal stem cells has been verified through various experiments and animal studies. Some successful bone regenerations have also been reported in difficult clinical situations, such as large bone defects, osteonecrosis, and nonunion. On the other hand, there are no standardized indications or application methods for each clinical situation, and convincing evidence of its efficacy and safety is still lacking. Bone regeneration therapies using mesenchymal stem cells are likely to expand further in the future, but there are some issues that need to be addressed in order for them be recognized as standard treatments.

Development of CANDU Pressure Tube Integrity Evaluation System;Its Application to Sharp Flaw and Blunt Notch (CANDU 압력관에 대한 건전성 평가시스템 개발;예리한 결함 및 둔한 노치에의 적용)

  • Gwak, Sang-Rok;Lee, Jun-Seong;Kim, Yeong-Jin;Park, Yun-Won
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.1 s.173
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    • pp.206-214
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    • 2000
  • The pressure tube is a major component of the CANDU reactor, which supports nuclear fuel bundle and it's containment vessel. If a flaw is found during the periodic inspection from the pressure tube s. the integrity evaluation must be carried out. and the safety requirements must be satisfied for continued service. In order to complete the integrity evaluation, complicated and iterative calculation procedures are required. Besides, a lot of data and knowledge for the evaluation are required for the entire: integrity evaluation process. For this reason. an integrity evaluation system, which provides efficient of evaluation with the help of attached databases, was developed. The developed system was built on the basis of ASME Sec. XI and FFSG(Fitness For Service Guidelines for zirconium alloy pressure tubes in operating CANDU reactors) issued by the AECL, and covers the delayed hydride cracking(DHC). This system does not only provide various databases including the 3-D finite element analysis results on pressure tubes, inspection data and design specifications but also is compatible with other commercial database software. In order to verify the developed system, several case studies have been performed and the results were compared with those from AECL. A good agreement was observed between those two results.

Consideration on the Perception Change for Radiation of High School Students through an Experiencing Program (체험학습을 통한 고등학생의 방사선 인식 변화에 대한 고찰)

  • Nam, Jong Soo;Kim, Yong Woo;Lee, Ji Sook;Seo, Kyung Won
    • Journal of Radiation Protection and Research
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    • v.39 no.1
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    • pp.65-69
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    • 2014
  • The Korean nuclear industry has been influenced by Fukushima nuclear accident of Japan which occurred two years ago. With information about the accident mainly through mass media such as television or internet, most people are inclined to have a negative perception about nuclear and radiation. They have lack of proper understanding of the fact. Especially, Korean students being future generation have a very limited chance to learn about nuclear and radiation from their regular school curricula. To meet this need, the effectiveness of an extra curricula program is studied using a set of survey on the change of knowledge and perception on radiation, which has been conducted by providing a radiation experiencing program, developed for this study, to high school students in Daejeon area. As a result, a large number of students are found to have enhanced their knowledge on radiation, while some students have shown their positive change of perception on radiation. Based on this, further study may need to improve the survey method and to promote its application for the development of more diverse and systematic radiation experiencing programs. Moreover, better ways for synergy between education and public relations activities on radiation safety may need to be sought.

A Study on Major Safety Problems and Improvement Measures of Personal Mobility (개인형 이동장치의 안전 주요 문제점 및 개선방안 연구)

  • Kang, Seung Shik;Kang, Seong Kyung
    • Journal of the Society of Disaster Information
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    • v.18 no.1
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    • pp.202-217
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    • 2022
  • Purpose: The recent increased use of Personal Mobility (PM) has been accompanied by a rise in the annual number of accidents. Accordingly, the safety requirements for PM use are being strengthened, but the laws/systems, infrastructure, and management systems remain insufficient for fostering a safe environment. Therefore, this study comprehensively searches the main problems and improvement methods through a review of previous studies that are related to PM. Then the priorities according to the importance of the improvement methods are presented through the Delphi survey. Method: The research method is mainly composed of a literature study and an expert survey (Delphi survey). Prior research and improvement cases (local governments, government departments, companies, etc.) are reviewed to derive problems and improvements, and a problem/improvement classification table is created based on keywords. Based on the classification contents, an expert survey is conducted to derive a priority improvement plan. Result: The PM-related problems were in 'non-compliance with traffic laws, lack of knowledge, inexperienced operation, and lack of safety awareness' in relation to human factors, and 'device characteristics, road-drivable space, road facilities, parking facilities' in relation to physical factors. 'Management/supervision, product management, user management, education/training' as administrative factors and legal factors are divided into 'absence/sufficiency of law, confusion/duplication, reduced effectiveness'. Improvement tasks related to this include 'PM education/public relations, parking/return, road improvement, PM registration/management, insurance, safety standards, traffic standards, PM device safety, PM supplementary facilities, enforcement/management, dedicated organization, service providers, management system, and related laws/institutional improvement', and 42 detailed tasks are derived for these 14 core tasks. The results for the importance evaluation of detailed tasks show that the tasks with a high overall average for the evaluation items of cost, time, effect, urgency, and feasibility were 'strengthening crackdown/instruction activities, education publicity/campaign, truancy PM management, and clarification of traffic rules'. Conclusion: The PM market is experiencing gradual growth based on shared services and a safe environment for PM use must be ensured along with industrial revitalization. In this respect, this study seeks out the major problems and improvement plans related to PM from a comprehensive point of view and prioritizes the necessary improvement measures. Therefore, it can serve as a basis of data for future policy establishment. In the future, in-depth data supplementation will be required for each key improvement area for practical policy application.