• Title/Summary/Keyword: Appearance frequency

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STUDY ON EXPRESSION OF GLYCOSAMINOGLYCAN IN ADENOID CYSTIC CARCINOMA (선양낭성암종(Adenoid Cystic Carcinoma)에서의 Glycosaminoglycan의 발현에 관한 연구)

  • Son, Chang-Won;Kim, Kyung-Wook;Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.4
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    • pp.271-281
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    • 2004
  • Adenoid cystic carcinoma is malignant tumor in salivary gland, and its behavior is very invasive. Of all malignant tumor adenoid cystic carcinoma is occured in frequency of 4.4% in major salivary gland, and 1.29% in minor salivary gland. Histopathologically, adenoid cystic carcinoma is characterized by a cribriform appearance, and tubular form and solid nest type tumor can be seen. The tumor cell structure composed of modified myoepithelial cell, and basaloid cell. Extracellular matrix of this tumor cell contains variable ground substance with basement membrane component. Basement membrane matrix composed of collagen fibers, glycoproteins, proteoglycans, and its function is well known that it participate in differentiation, proliferation, and growth of tumor cell. Basement membrane molecule is essential for invasion of peripheral nerve, blood vessel, skeletal muscle in tumor cell of adenoid cystic carcinoma. In many studies, the tumor cell of adenoid cystic carcinoma containing modified myoepithelial cell participate in synthesis of proteoglycan. In this study, tissue sample of adenoid cystic carcinoma of human salivary gland were obtained from 15 surgical specimen, and all specimen were routinely fixed in 10% formalin and embedded. Serial $4-{\mu}m$ thick sections were cut from paraffin blocks. the histopathologic evaluation was done with light microscopy. And, the immunohistochemical staining, characteristics of glycosaminoglycan were observed. For biochemical analysis of glycosaminoglycan, isolation of crude glycosaminoglycan from tumor tissue and Western bolt analysis were carried out. With transmission electomicroscopy, tumor cell were observed. Biologic behavior of adenoid cystic carcinoma was observed with distribution and expression of basement membrane of glycosaminoglycan in tumor cells, The results obtained were as follows: 1. In immunohistochemical study, chondroitin sulfate is postively stained in tumor cell and interstitial space, dermatan sulfate is weakly stained in ductal cell. But keratan sulfate is negatively stained. 2. In immunohistochemical study, heparan sulfate is strong positive stained in tumor cell and basement membrane, especially in invasion area to peripheral nerve tissue. 3. In transmission electromicroscpic view, the tumor cells are composed modifed myoepithelial cells, and contains many microvilli and rough endoplasmic reticulum. 4. In Western blot analysis, the expression of glycosaminoglycan is expressed mostly in heparan sulfate. From the results obtained in this study, tumor cell of adenoid cystic carcinoma is composed modified myoepithelial cell, and glycosaminoglycan of basement membrane molecule of heparan sulfate and chondroitin sulfate mostly participate in the development and invasiveness of adenoid cystic carcinoma by immunohistochemical study and western blot analysis.

Comparative Analysis of Clinical and Histopathological Appearance Between Oral Leukoplakia and Lichen Planus (구강 백반증과 편평태선의 임상·병리조직학적 소견 비교 분석)

  • Ryu, Mi-Heon
    • Journal of dental hygiene science
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    • v.5 no.4
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    • pp.199-204
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    • 2005
  • Background : Oral leukoplakia(OL) and lichen planus(LP) are common soft tissue lesions characterized by white plaque or striae with erosion. The clinical characteristics of these diseases are similar but the cause and clinical course of them are very different. I compared OL with LP by analysizing clinical and histopathological characteristics and follow up study. Patients and methods : The clinical analysis of 200 patients with OL and LP was performed by review of dental and medical charts. And H/E slides were examined under the light microscope. we examined H/E slides by the light microscope. The follow up study of patients was performed. Statistical analysis was done using the SPSS/PC WINDOWS (version 13.0). Results : The age distribution of OL was in the range of 13-75 years old being most prevalent in the 5th decade and there was a tendency of male prevalent. The age distribution of LP was in the range of 20-79 years old being most prevalent in the 4th decade and there was a tendency of female prevalent. The most common site of involvement was the buccal mucosa in both diseases. The most common clinical features of OL and LP were white plaque type and white lesion with striae, respectively. In case of LP, the most common clinical sign was tenderness to palpation. Fifteen cases of OL and eight cases of LP showed epithelial dysplasia. Twelve cases of OL recurred after surgery of oral squamous cell carcinoma and 2 cases of LP were transformed into oral squamous carcinoma. Conclusion : There was statistically significant difference in age, sex, clinical signs of patients, frequency of epithelial dysplasia between OL and LP. The Pearson coefficient correlation efficient was 0.51(p < 0.05). The knowledge of the difference between OL and LP can help understand these diseases.

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Histopathological studies on melano - macrophage centers (MMCs) in spleen and head kidney of immuno - modified tilapia, Oreochromis niloticus (틸라피아(Oreochromis niloticus)의 면역활성변화와 Melano - Macrophage Centers (MMCs)의 행동특성에 관한 병리조직학적 연구)

  • Park, Jeong-Hee;Huh, Min-Do
    • Journal of fish pathology
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    • v.7 no.2
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    • pp.127-149
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    • 1994
  • Histopathological studies on the two lymphomyeloid organs of spleen and head kidney in tilapia, Oreochromis niloticus, were carried out to clarify the significance on the morphological characteristics of melano - macrophage centers (MMCs) which are varied in different physiological and pathological conditions of teleosts. To examine the histological changes by the artificial modification of the immunological states, tilapia were treated intraperitoneally with FKC and LPS of Edwardsiella tarda, and orally with dexamethasone, and then followed by the intraperitoneal injection of colloidal carbon for chasing the macrophages. There were marked differences in phagocytic avidity of macrophages, and accumulating patterns of carbon - ladening macrophages into the MMCs among the test groups. In the non - pretreated control group, carbon - ladening macrophages were densely accumulated at 12th and 20th day within the MMCs of head kidney and spleen, respectively. And, in the groups treated with bacterial antigens (FKC & LPS), the macrophages were more rapidly and densely aggregated within MMCs. But in the group with dexamethasone, only a few carbon particles were detected in both organs. Any compactly isolated form of particles was not found in this group. From the present results, it was strongly suggested that certain changes in immunological states of tilapia influence on the morphology of MMCs including the frequency of appearance, sizes, aggregating patterns or outlines. Therefore, morphology of MMCs would be very important in the interpretation for histopathological findings seen in the teleost's lymphomyeloid organs.

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CLASS II COMPOSITE RESIN RESTORATION USING ORTHODONTIC BANDS (교정용 밴드를 이용한 구치부 2급 와동의 복합레진 수복)

  • Park, Sung-Dong;Park, Ki-Tae
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.1
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    • pp.13-17
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    • 2005
  • Children and teenagers have a higher frequency of proximal surface caries in the posterior teeth than adults. For proximal restoration, class II amalgam or stainless steel crown has been widely used in the past, however composite resin restoration is getting ore popular due to it's superior cosmetic appearance. When applying composite resin on proximal area, various types of matrix bands can be utilized according to the operator's reference or skill. Such bands have several clinical effects including suitability for proximal margin, reduction of micro-leakage, moisture-control against saliva and ease finishing and polishing. In this case report, orthodontic bands were utilized instead of matrix bands as a remedy for proximal restorations in both primary and permanent teeth and their clinical advantages are as follows. 1. Orthodontic bands showed superior marginal adaptation compared to conventional matrix bands and moisture-control against saliva was excellent. 2. While applying composite resin, deformation of restoration material was estimated to be insignificant due to he rigidity of the orthodontic bands. 3. Natural tooth contour of the orthodontic bands facilitates to reproduce proximal tooth contour of the restoration. 4. In general, pediatric dentists are accustomed to applying orthodontic bands and this may allow pediatric dentists to make proximal composite restorations more efficiently than other dental specialists.

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A Study on 17th and 18th Century Common People's Costumes in France (17~18세기 프랑스 서민복식 연구)

  • Kim, Yang-Hee;Kim, Hyun-Joo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.9
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    • pp.901-915
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    • 2012
  • This study comparatively analyzes the characteristics, changes, and differences in class-based costume typology according to a concept of $17^{th}$ and $18^{th}$ century common people in France. The methods and contents are as follow. First, the scope of common people is grasped according to the historical background and a concept of $17^{th}$ and $18^{th}$ century common people in France. Second, through considering a prior research on analyzing the data of ancient documents on the economy of clothing, it classifies common people into bourgeoisie, urban common people, rural common people, and the destitute. It then examines diachronic evolution, and class-based synchronic difference in the consumption of $17^{th}$ and $18^{th}$ century common people's costumes in France. Third, it analyzes the appearance frequency by period according to type of common people's costumes, which were shown in pictorial materials with 283 sheets of engravings and 54 pieces of paintings; in addition, it reconstructs the succession and expansion in typology. It grasps differences and changes in morphology by class, space, and period of typology for common people's costumes. Common people's consumption of costumes was understood to have grown in qualitative aspects as well as a rise in the whole clothing demand. A class-based structure formed and indicated that a fashion cycle existed. As a result of analyzing common people's clothes (shown in pictorial materials of the $17^{th}$ and $18^{th}$ century) 41 items were grasped by gender and according to costume kind. Typology in common people's costumes (classified into bourgeoisie, urban common people, rural common people, and the destitute) showed a change by period. A change in typical costume typology was accepted more by the bourgeoisie than by urban and rural common people, and was accepted more by rural communities than by urban populations. Thus, a difference was formed through an expansion with a temporal difference that depended on class and space.

Research Trends of the Jellyfish Blooms (해파리 대량발생의 연구동향)

  • Chung, Mi-Hee;Youn, Seok-Hyun;Yoon, Won-Duk
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.17 no.1
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    • pp.25-31
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    • 2012
  • The frequency and abundance of jellyfish, presumably related with climate change, fisheries overexploitation, marine pollution including land reclamation and dyke construction, are increasing worldwide. This feature has attracted interest and concerns from general public and public officials, and government is seeking how the damages could be prevented or reduced down. Korean government, having recent huge blooms of jellyfish, engaged in reducing and/or countermeasuring jellyfish damages. Korean research themes include ecology and physiology of blooming jellyfish species, understanding of the blooming mechanism, and focus on the eradication of blooming jellyfish, without governmental integrative management plan. EU is undertaking scientific projects focused on understanding of the mechanism and control of jellyfish blooms, and establishment of an integrative management. In USA, government has established the code on jellyfish management for conserving and protecting the fish and shellfish resources and one of its department is specially assigned to monitor jellyfish appearance, undertake research, and prepare management plan. Japan also assigned a department and research institute for jellyfish research. Their main interest is to predict jellyfish drifting and mass bloom. Compared to Korea, USA, EU and Japan emphasize integrative management that includes ecological understanding, public education and outreaches, communication and control, if possible, of jellyfish blooms, based on scientific data. We suggest then, 1) establishment of an integrative scientific system consisting of policy and scientific experts to prepare inter-ministrial integrative management plan to effectively combat jellyfish blooms and to maximize the scientific result; 2) concept change from harmful to exploitable marine animal in policy making and research; and 3) active education and information service for people. We expect that these suggestions can be useful for jellyfish management and policy making on another harmful marine organisms.

Analysis of influential factors on respiratory symptoms of nail shop workers

  • Kim, Jung-ae;Kim, Su-min
    • International Journal of Advanced Culture Technology
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    • v.5 no.3
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    • pp.24-34
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    • 2017
  • Nail art is a kind of nail painting or decoration that adds to the beauty. Throughout making nail art, the worker was on a dusty operation with the smoothing of chemicals and nails. People working at nail shops not only use a variety of chemicals, but also experience a lot of fine powder during the process of nail trimmings. While drying the chemical adhesive, the workers often complain of eye, nose and throat discomfort. In addition, the acrylic brush is characterized by a lot of smell when washed with washing solution. Also nail art workers directly influence the worker's breathing through the work done by placing the guest's hands in a work space called a nail table. Chemical ingredients used in nail art procedures include acetone, ethyl acetic acid, toluene, butyl acetic acid, glue, and top coating of nail varnishes. Prolonged inhalation of these substances may cause dizziness, vomiting, as well as impaired respiratory system. The purpose of this study is to investigate the respiratory symptoms of nail shop workers who are likely to be affected by work in nail shop and to find out which factors have the greatest influence if they have respiratory symptoms. Therefore this study is to provide basic data on the health management system of people engaged in nail shop and to develop health education program. For this study, the data collection was collected on July 7, 2017 for the nail shop workers attending the nail art trend seminar held in Gwangju, in Korea. The data were all 236. However, except for the poor data, 208 data were used for the final analysis. The questionnaire consisted of 30 in general questions, questions about self-efficacy in 24 questions. elf-efficacy measuring tool developed by A.Y, Kim, I. Y, Park(2001). The self-efficacy questionnaire consists of 24 items and is self-reported 7-point Likert scale. The reliability of this tool was cronbach alpha = .934.The collected data were analyzed using spss 18.0. Information of Research participant performed frequency analysis. To examine the effects of personal characteristics on self-efficacy, $X^2$ analysis was conducted. And also $X^2$ analysis was conducted to analyze the coughing symptom appearance according to individual and environmental factors. A hierarchical regression analysis was used to determine which of the personal and environmental factors influenced cough symptoms.

A Study On Malocclusion Patients From Department Of Orthodontics, Chong-A Dental Hospital (청아치과병원 교정과에 내원한 환자의 분포와 부정교합의 유형)

  • Kim, Nam-Joong;Lee, Chung-Jae
    • Journal of Technologic Dentistry
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    • v.29 no.2
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    • pp.197-211
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    • 2007
  • With the development of orthodontics and increasing concerns on physical appearance, the number of patients has been steadily increasing. It is quite important not only to make effective cure plans and accurate diagnoses but also to have a thorough grasp of patients' malocclusion types and their occurrence frequency, in addition to patients' personality in order to cure the patients appropriately. This study is based on 946 malocclusion patients who had visited Chong-A Dental Hospital from 1999 to 2004 and investigated their aspects of malocclusion and characteristics of their gender, age and residence. The results are as follows. 1. The number of patients per year had been decreased until 2001, after which year the number had fluctuated. The number was the largest in 1999, 169 and the smallest in 2001, 140. Female occupied 68.0% of the total, twice as many as male, 32.0%) 2. Based on the Angle's classification, 19 or over year - old group was the largest of the total, 59.3% and 6 or younger year - old group, the smallest, 0.5%. The 19 or over year old group was less than a half of the total (47.4%) in 2003 and there were no patients who belonged to the 6 or younger year - old group in 2003 and 2004. 3. Distributions on the types of malocclusion have shown that 39.9 % of the total are in the Class I, the largest, 31.0% in the Class I and 29.2 in the Class II, the smallest. 1) The number of the ClassI was 73, the largest, that of the Class III being 35, the smallest in 1999. On the whole, the number of the Class I accounted for the largest part of the total. 2) The number of male patients in the Class II was the smallest, generally being the largest in the Class I. In case of female, that of the Class III was the smallest. 3) Based on the age, the Class I was the highest in between 7 and 13 age group, the Class III the lowest. The Class I occupied the largest around 40%. 4) In the shape of physiognomy, the meso occupied the largest part among all the Class, of which the Class II was the highest, 64.2%. The bracy was the largest in the Class I, and the dolicho in the Class III. 5) In the profile, the convex shape was the largest in the Class I and II, and especially in the Class II, over 3/4 of the total, 75.4%. In contrast, the direct shape was the largest in the Class III and the sunken shape occupied 33.3%, which was nearly ten times more than the case of the Class I and III. 6) In the asymmetry of physiognomy, the number of patients of the Class IIIwas the largest, 34.1% and that of the Class II, the smallest, 19.5%. It was found that about one fourth of the malocclusion patients were under the asymmetry of physiognomy. 4. In the distribution of patients' residence, 81.4% were from the Seoul Metropolis and 48.2% from Gangnam-Gu where Chong-A Dental Hospital is located and Seocho-Gu and Songpa-Gu which are adjacent to Gangnam-Gu.

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Reproductive Cycle in Female Fusilier, Caesio diagramma (농어목 어류, Caesio diagramma 암컷의 생식주기)

  • Choi Cheol Young;Chang Young Jin;Takemura Akihiro;Takano Kazunori
    • Journal of Aquaculture
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    • v.9 no.1
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    • pp.73-81
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    • 1996
  • This study was conducted to study the reproductive cycle in female fusilier, Caesio diagramma by using the histological methods. Histological changes of the ovary were well correlated with the patterns of gonadosomatic index (GSI) and hepatosomatic index (HSI). GSI was increased in April as the value of HSI increase and reached to its maximum in May and June. Oocytes at the chromatin-nucleolus and peri-nucleolus stages were observed in the ovary throughout the year. In April, oocytes containing yolk appeared in ovaries of a few fishes. Most oocytes appearing in May and June belonged to the tertiary yolk stage. Frequency of oocytes appearance at the tertiary yolk stage in May and June was higher than that of the other months. Moreover, the empty follicles and atretic oocytes were observed in the ovaries with many vitellogenic oocytes during these two months. Thereafter, oocytes of the yolk stage disappeared in September. The spawning period of C. diagramma is from the month of April to June, and this species belongs to an asynchronous and multiple spawner.

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Upper Garment Sizing System for Obese School Boys Based on Somatotype Analysis (학령후기 비만 남아의 체형 분석에 따른 plus-size 남자 아동복 상의 치수 규격 제안)

  • Park, Soon-Jee
    • Journal of the Korean Home Economics Association
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    • v.46 no.9
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    • pp.99-112
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    • 2008
  • The increasing rate of obesity in school aged children has become a conspicuous social phenomenon in Korea. This has been linked to greater economic growth, increasingly westernized dietary habits, and a consumer driven society. Given that obesity can lead to social exclusion or unfavorable attention by other students in a school setting, the design of plus-size garments have become important for effective appearance management skills. This research aimed to establish a somatotype database for obese school boys, aged 10 to 12, in order to develop a sizing system for plus-size upper garments. In order to measure somatotype of average and obese school boys, five categories were recorded; height, obesity, length of trunk, thickness of neck and chest. For obese boys, subcutaneous fat thickness and position of B.P/shoulder point factors were recorded. Obesity factor was subdivided into overall and specific ones, and while the deviation of obese body types was severe compared to the average type. Obese body type showed significantly higher measurements in width, girth, thickness. This is linked to the fact that the frequency ratio of obesity increases with age. Stature and chest were chosen as control dimensions for boys' wear. As crosstabulation of stature(5cm interval) and chest girth(2, 3 and 4cm), and stature(5cm interval)/chest girth(3cm interval) sizing system showed, the most effective cover ratio and adaptability to the data distribution $25{\sim}75$ quartile. Based on the findings, 10 sizes were formulated for average body type, while 18 sizes were formulated for obese type, whose size cover ratios were 48% and 62.9%, respectively. The primary ranges of stature were $145cm{\sim}150cm$, while those of chest girth were $79{\sim}82cm$. Each size was declared as "chest-somatotype{A(average)/O(obesity)-stature". This study proposed a plus-size upper garment sizing systems for obese boys, accompanied with reference measurements for suit, casual wear and underwear. The finding showed that the two systems were totally separate and not overlapping, meaning that plus-size sizing system is essential for obese school boys. The obesity type system had more size and wider range specs.