• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2004.09a
• /
• pp.186-190
• /
• 2004

The electrokinetic bioremediation employing electrolyte circulation method was carried out for the cleanup of phenanthrene-contaminated kaolinite, and microorganism used in the biodegradation of phenanthrene was Sphingomonas sp. 3Y. The electrolyte circulation method supplied ionic nutrientsand the microorganism into soil, and inhibited the significant pH change of soil by increasing the soil buffering capacity by providing phosphate buffer compounds. When the remediation process was conducted without surfactant, the removal efficiency of phenanthrene, at the initial concentration of 200 ppm, was 69% for only 7 days. Higher microbial population and lower phenanthrene concentration were observed in the anode and middle regions of soil specimen than in the cathode region. The higher density of microorganism was because the microbial movement was in the direction of the anode part due to the negative surface charge. When Triton X-100 and APG of 20 g/1 were used to improve the bioavailability of phenanthrene strongly adsorbed onto soil surface, about 90 and 39% of phenanthrene removal were obtained. Consequently, it was confirmed that the microorganism preferred APC to phenanthrene as carbon source and so the removal efficiency with APG decreased less than that without APG.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.10
• /
• pp.5003-5006
• /
• 2012

Objective: Yanting County is a high risk area for esophageal cancer (EC) in China. The purpose of this study was to describe the mortality and mortality change of EC from 2004 to 2009 in Yanting County. Methods: EC mortality data from 2004 to 2009 obtained from the Cancer Registry in Yanting were analyzed. Annual percentage changes (APC) were calculated to assess the trends in EC mortality. Age-standardized mortality was calculated based on world standard population of 2000. Results: The average EC mortality was 54.7/$10^5$ in males and 31.6/$10^5$ in females over the 6 years. A decline in EC mortality with time was observed in both genders, with a rate of -8.70% per year (95% CI: -13.23%~-3.93%) in females and -4.11% per year (95%CI: -11.16%~3.50%) in males. Conclusion: EC mortality decreased over the six years in both genders, although it remained high in the Yanting area. There is still a need to carry out studies of risk factors for improved cancer prevention and further reduction in the disease burden.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.14
• /
• pp.5909-5916
• /
• 2014

Human papillomavirus infection (HPV) and HPV related immune perturbation play important roles in the development of cervical cancer. Since mature dendritic cells (DCs) are potent antigen-presenting cells (APC), they could be primed by HPV antigens against cervical cancers. In this study we were able to generate, maintain and characterize, both phenotypically and functionally, patient specific dendritic cells in vitro. A randomized Phase I trial with three arms - saline control (arm I), unprimed mature DC (arm II) and autologous tumor lysate primed mature DC (arm III) and fourteen patients was conducted. According to WHO criteria, grade 0 or grade one toxicity was observed in three patients. One patient who received tumor lysate primed dendritic cells and later cis-platin chemotherapy showed a complete clinical response of her large metastatic disease and remained disease free for more than 72 months. Our findings indicate that DC vaccines hold promise as adjuvant sfor cervical cancer treatment and further studies to improve their efficacy need to be conducted.

• BMB Reports
• /
• v.48 no.7
• /
• pp.369-370
• /
• 2015

Actin dynamics is critical for the formation and sustainment of the immunological synapse (IS) during T cell interaction with antigen-presenting cells (APC). Thus, many actin regulating proteins are involved in spatial and temporal actin remodeling at the IS. However, little is known whether or how actin stabilizing protein controls IS and the consequent T cell functions. TAGLN2 − an actin-binding protein predominantly expressed in T cells − displays a novel function to stabilize cortical F-actin, thereby augmenting F-actin contents at the IS, and acquiring leukocyte function-associated antigen-1 activation following T cell activation. TAGLN2 also competes with cofilin to protect F-actin in vitro and in vivo. During cytotoxic T cell interaction with cancer cells, the expression level of TAGLN2 at the IS correlates with the T cell adhesion to target cancer cells and production of lytic granules such as granzyme B and perforin, thus expressing cytotoxic T cell function. These findings identify a novel function for TAGLN2 as an actin stabilizing protein that is essential for stable immunological synapse formation, thereby regulating T cell immunity. [BMB Reports 2015; 48(7): 369-370]

• Transactions of the Korean Society of Pressure Vessels and Piping
• /
• v.8 no.2
• /
• pp.26-32
• /
• 2012

The systems of the nuclear power plant are designed based on the User Requirement Document, and Korea Hydro & Nuclear Power Co. (KHNP) implements preventive maintenance activities to keep the specific design function of the system consistently. To monitor the preventive maintenance effectiveness, KHNP has also developed maintenance effectiveness monitoring (MR) program based on NUMARC 93-01 since 2003, and has implemented the program in all operating plants. Recently, KHNP has upgraded MR programs by reflecting implementing experiences ; reestablishing the performance monitoring level, improving analysis for standby function and performance criteria for passive components, reestablishing the availability performance criteria and the performance criteria for the same type of components. These upgraded MR programs will contribute to enhance safety and improve equipment reliability through monitoring maintenance effectiveness.

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 2012.11a
• /
• pp.92-95
• /
• 2012

대한민국에서 3DTV 방송서비스는 더 이상 '미래방송서비스'가 아니다. EBS는 올해 4월 지상파 DTV 주파수에서 세계최초로 2D/3D 혼용방송서비스를 실시하였으며, 오는 10월 15일에는 APC(Automatic Program Controller)와 연동하여 방송스케줄에 따라 자동으로 3D 방송을 송출하는 시스템을 구축하여 2차 시범방송을 진행할 예정이다. 이렇게 3D 방송을 위한 기술적 준비는 차근차근 이루어지고 있음에 반하여, 3D 방송서비스에 대한 시청자의 호응은 그다지 크지 않다. 이것은 방송되는 3D 콘텐츠의 양과 질이 부족하기 때문으로 풀이된다. 이 같은 3D 방송서비스의 장애요소에 착안하여, 본 논문에서는 3D 콘텐츠 제작효율을 높이고, 만들어지는 3D 방송콘텐츠의 품질을 높이기 위한 하나의 방법으로서, 제작현장에서 활용할 수 있는 3D 콘텐츠 제작과 밀접한 관련이 있는 새로운 참조지표인 '입체충실도(Depth Fidelity)'를 정의하여 제안하고자 한다. 입체충실도를 도출하기 위해 우선 양안식(兩眼式) 3D 입체영상의 특징을 분석하였고, 시청자 체감 가상깊이를 계산하여 활용하였다. 또한 연구를 통해 도출한 입체충실도 계산 알고리즘이 적용된 EBS 입체계산기(Stereoscopic Calculator) 애플리케이션을 개발하여 안드로이드 스마트폰에서 이용할 수 있도록 함으로써, 카메라감독과 프로듀서 등 방송제작 현업 스태프들이 연구결과를 활용할 수 있도록 했다.

• The Korean Journal of Ecology
• /
• v.14 no.1
• /
• pp.87-99
• /
• 1991

Changes of phycobiliproteins(PBP) quantity and ferredoxin-NADP reductase(FNR) activity were investigated in various light illuminated cyanobacteria, Anabaena variabilis. PBP components were increased under blue light illumination, whereas decreased under red light illumination. PBP contents were twofolds in blue light than in red light. In view of the PBP composition, allophycocyanin(APC) in red light was higher 5.5% and phycoerythrocyanin(PEC) in blue light was higher 2.2% than in white light-illuminated PBP. It was suggested that PBP changes in bule light be the results of regulation of photosysthetic efficiency and protection of photosystem, whereas PBP changes in red light be effected by adaptation of adequate harvesting of light energy in photosystem. Changes of FNR activity were highest in red light, and sequenced lower to blue light and green light. It means that light-dependent production rate of NADP is the highest in red light. The difference of values was larger than that of values in comparison of red and blue light. It was suggested that increasing of FNR activity be due not to the function of isozyme, but to the synthesis of enzymes. Because of NAD/NADP regulation-effect to metabolism, it was considered that FNR activity might influence the metabolism indirectly and explain the probability of regulation in pathways of key enzyme activation. FNR activity was directly proportional to intensity of light. Optimum temperature and pH were about 25℃ and 7.5, respectively.

• Journal of Ocean Engineering and Technology
• /
• v.1 no.2
• /
• pp.113-122
• /
• 1987

Ships and offshore strrctures are exposed to the corrosive surroundings, and the extablishment of the design criteria and the elucidation on the influence by this environment are requested to maintain the safety and to demonstrate the function of the structure. In this paper, the fatigue-crack-growth behavior on the compact tension specimens of quenched, tempered HT80 grade steels and RA36 high tensile steels having a single edge fatigue cracked notch respectively, were investigated under the repeated tensile stress with constant stroke in sea water for the welded parts by shielded metal arc welding. Main results obtained are summerized as follows; 1. The fatigue-crack-growth rates da/dN in sea water appeared to be greater behavior than those in air environment at the same stress intensisy factor range $\DeltaK$. 2. The correlation data of da/dN$\DeltaK$ of the two kinds of high tensile steels in sea water showed no great difference, however, the correlation data of da/dN$\DeltaK/\sigma_y$($\sigma_y$ stands for yield strength of the material) showed that the fatigue-crack-growth behavior of RA36 plate is affected by active path corrosion(APC) mechanism, while that of HT80 grade plate is mainly affected by hydrogen embrittlement mechanism.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.35 no.9B
• /
• pp.1322-1329
• /
• 2010

As body sensor network (BSN) research becomes mature, the need for managing power consumption of sensor nodes has become evident since most of the applications are designed for continuous monitoring. Real time Electrocardiograph (ECG) analysis on sensor nodes is proposed as an optimal choice for saving power consumption by reducing data transmission overhead. Smart sensor nodes with the ability to categorize lately detected ECG cycles communicate with base station only when ECG cycles are classified as abnormal. In this paper, ECG classification algorithms are described, which categorize detected ECG cycles as normal or abnormal, or even more specific cardiac diseases. Our Euclidean distance (ED) based classification method is validated to be most power efficient and very accurate in determining normal or abnormal ECG cycles. A close comparison of power efficiency and classification accuracy between our ED classification algorithm and generalized linear model (GLM) based classification algorithm is provided. Through experiments we show that, CPU cycle power consumption of ED based classification algorithm can be reduced by 31.21% and overall power consumption can be reduced by 13.63% at most when compared with GLM based method. The accuracy of detecting NSR, APC, PVC, SVT, VT, and VF using GLM based method range from 55% to 99% meanwhile, we show that the accuracy of detecting normal and abnormal ECG cycles using our ED based method is higher than 86%.

• Journal of the Korea Safety Management & Science
• /
• v.19 no.1
• /
• pp.157-167
• /
• 2017

The two-way quality theory has been widely used as a method for classifying quality attributes for several decades. In particular, the Kano model that classifies attributes into not just conventional one-dimensional but must-be and attractive has gained popularity due to its applicability and ease of use. However, the wordings of the five alternatives in the Kano's questionnaire has been criticised for unclear meanings. This study proposes a new two-way model to classify attributes using 5-point Likert scale alternatives. For this, the current paper investigated a case of TV sets to examine how the proposed model works in comparison with the Kano model. The application results of the proposed model are different from the original one. The two-way model classifies quality attributes in more detail such as the "one-dimensional with an attractive tendency" attribute, which has a greater influence on satisfaction than dissatisfaction, the opposite "one-dimensional with a must-be tendency" attribute, and "highly one-dimensional" and "less one-dimensional" attributes. In this study, a potential satisfaction coefficient (PSC), a potential dissatisfaction coefficient (PDC), and an average potential coefficient (APC) to manage quality attributes are proposed and discussed for their utilization.