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One-Touch Type Immunosenging Lab-on-a-chip for Portable Point-of-care System (휴대용 POC 시스템을 위한 원터치형 면역 센싱 랩온어칩)

  • Park, Sin-Wook;Kang, Tae-Ho;Lee, Jun-Hwang;Yoon, Hyun-C.;Yang, Sang-Sik
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.8
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    • pp.1424-1429
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    • 2007
  • This paper presents a simple and reliable one-touch type multi-immunosensing lab-on-a-chip (LOC) detecting antibodies as multi-disease markers using electrochemical method suitable for a portable point-of-care system (POCS). The multi-stacked LOC consists of a PDMS space layer for liquids loading, a PDMS valve layer with 50 im in height for the membrane, a PDMS channel layer for the fluid paths, and a glass layer for multi electrodes. For the disposable immunoassay which needs sequential flow control of sample and buffer liquids according to the designed strategies, reliable and easy-controlled on-chip operation mechanisms without any electric power are necessary. The driving forces of sequential liquids transfer are the capillary attraction force and the pneumatic pressure generated by air bladder push. These passive fluid transport mechanisms are suitable for single-use LOC module. Prior to the application of detection of the antibody as a disease marker, the model experiments were performed with anti-DNP antibody and anti-biotin antibody as target analytes. The flow test results demonstrate that we can control the fluid flow easily by using the capillary stop valve and the PDMS check valves. By the model tests, we confirmed that the proposed LOC is easily applicable to the bioanalytic immunosensors using bioelectrocatalysis.

IoT-based low-cost prototype for online monitoring of maximum output power of domestic photovoltaic systems

  • Rouibah, Nassir;Barazane, Linda;Benghanem, Mohamed;Mellit, Adel
    • ETRI Journal
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    • v.43 no.3
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    • pp.459-470
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    • 2021
  • This paper presents a low-cost prototype for monitoring online the maximum power produced by a domestic photovoltaic (PV) system using Internet of Things (IoT) technology. The most common tracking algorithms (P&O, InCond, HC, VSS InCond, and FL) were first simulated using MATLAB/Simulink and then implemented in a low-cost microcontroller (Arduino). The current, voltage, load current, load voltage, power at the maximum power point, duty cycle, module temperature, and in-plane solar irradiance are monitored. Using IoT technology, users can check in real time the change in power produced by their installation anywhere and anytime without additional effort or cost. The designed prototype is suitable for domestic PV applications, particularly at remote sites. It can also help users check online whether any abnormality has happened in their system based simply on the variation in the produced maximum power. Experimental results show that the system performs well. Moreover, the prototype is easy to implement, low in cost, saves time, and minimizes human effort. The developed monitoring system could be extended by integrating fault detection and diagnosis algorithms.

A Comparison of Patient-specific Delivery Quality Assurance (DQA) Devices in Radiation Therapy (방사선치료에서 환자맞춤형 선량품질보증 장치의 비교)

  • Kyung Hwan Chang
    • Journal of radiological science and technology
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    • v.46 no.3
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    • pp.231-238
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    • 2023
  • This study aimed to compare the results of delivery quality assurance (DQA) using MapCHECK and OCTAVIUS for radiation therapy. Thirty patients who passed the DQA results were retrospectively included in this study. The point dose difference (DD) and gamma passing rate (GPR) were analyzed to evaluate the agreement between the measured and planned data for all cases, Plan complexity was evaluated to analyze dosimetric accuracy by quantifying the degree of modulation according to each plan. We analyzed the monitor units (MUs) and total MUs for each plan to evaluate the correlation between the MUs and plan complexity. We used a paired t-test to compare the DD and GPRs that were obtained using the two devices. The DDs and GPRs were within the tolerance range for all cases. The average GPRs difference between the two devices was statistically significant for the brain, and head and neck for gamma criteria of 3%/3 mm and 2%/2 mm. There was no significant correlation between the modulation index and total MUs for any of the cases. These DQA devices can be used interchangeably for routine patient-specific QA in radiation therapy.

A Composition Check of Composite Refactorings Not Having a Specification of Precondition (선행조건이 명세되어 있지 않은 복합 리팩토링에 대한 조립성 검사)

  • Kim, Kyung-Min;Jang, Pil-Jae;Kim, Tae-Gong
    • The KIPS Transactions:PartD
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    • v.18D no.1
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    • pp.23-34
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    • 2011
  • Refactoring has been actively used in recent software developments. Many studies on the processing of more large scaled composite refactorings have been conducted through the composition of elementary refactorings. It is important to verify the possibility of composition before the refactoring is performed, because the composite refactorings are processed to the sequence of composed elementary refactorings. In conventional studies, they verify the possibility of composition using the precondition of composite refactorings which are computed from the precondition and postcondition of elementary refactorings. They can not verify the possibility of composition in case which composite refactorings do not have a specification of precondition. Thus, we plan to verify the possibility of composition by using the elementary refactorings only without any additional definitions of the preconditions of composite refactorings. To achieve this goal, we proposes a specification method of elementary refactorings and a method for the composition check of refactorings. Then, we develop a prototype tool based on these methods. In addition, we verify the efficiency of our methods through case studies.

Measurement of S/W Development Processes and Maturity using Agile Methodologies (Agile 방법론을 이용한 S/W개발 프로세스 및 성숙도 측정)

  • Kim, Tai-Dal
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.6
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    • pp.147-154
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    • 2015
  • Recently agile development process became increasing effectiveness, quality, attention to experts in customer satisfaction, as evidenced in this methodology when selecting projects promoting productive efficiency. With regard to contemporary needs and user requirements on the methodology selected to meet this paper is the product based Cross functional team suggested methodology Feature Team model to solve problems of this model, and organizing the Cross functional team, this team but this outcome (product) basis, were examined for the model that points to progress the development across multiple product as a functional unit, value-driven agile project through the Skills-based model and proposed a difference. And it examined the Agile Maturity metrics. PRINCE2 Agile Health-check entries future development direction of Agile techniques is a requirement of the project outset has studied the subject objective evaluation by the assumption that they can be changed at any time, not fixed this way and for the project team through research The proposed.

Study on Measuring Geometrical Modification of Document Image in Scanning Process (스캐닝 과정에서 발생하는 전자문서의 기하학적 변형감지에 관한 연구)

  • Oh, Dong-Yeol;Oh, Hae-Seok;Rhew, Sung-Yul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.8
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    • pp.1869-1876
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    • 2009
  • Scanner which is a kind of optical devices is used to convert paper documents into document image files. The assessment of scanned document image is performed to check if there are any modification on document image files in scanning process. In assessment of scanned documents, user checks the degree of skew, noise, folded state and etc This paper proposed to how to measure geometrical modifications of document image in scanning process. In this study, we check the degree of modification in document image file by image processing and we compare the evaluation value which means the degree of modification in each items with OCR success ratio in a document image file. To analyse the correlation between OCR success ratio and the evaluation value which means the degree of modification in each items, we apply Pearson Correlation Coefficient and calculate weight value for each items to score total evaluation value of image modification degrees on a image file. The document image which has high rating score by proposed method also has high OCR success ratio.

Vacuum Drying Characteristics Using Different Heating Methods for Douglas-fir Timber (미송 대단면재의 가열법에 따른 진공건조 특성)

  • Jung, Hee-Suk;Eom, Chang-Deuk;So, Bum-Joon
    • Journal of the Korean Wood Science and Technology
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    • v.32 no.4
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    • pp.18-26
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    • 2004
  • Timbers of 14 by 14 cm, 2.4 m long, were dried in a vacuum kiln to investigate vacuum drying characteristics using three types of heating methods, conduction heating with hot plate, the radio frequency (RF) heating and the combination of both (hybrid heating). Average drying rate is the highest for the hybrid heating and the lowest for the RF heating. Average specific energy is the highest for the RF heating and the lowest for conduction heating. Transverse moisture content distribution of dried timber revealed the convex profile for both conduction and the hybrid heating and moisture content increased from one face to the opposite face for the RF heating. Moisture content distribution along the length of timber increased from the end to the middle of timber length for conduction and the hybrid heating and decreased from the end to the middle of timber length for the RF heating. End- and surface checks for conduction heating were severer than the other heating methods. No internal check occurred in any heating methods. Drying characteristics of conduction heating showed in-between trend of the RF and the hybrid heating.

Subjective Health, Subjective Oral Health, and EQ-5D Level of Adults According to Health Management and Oral Health Management Behavior (성인들의 건강관리와 구강건강관리행태에 따른 주관적 건강과 구강건강, EQ-5D수준)

  • Chung-Mu Park;Hyun-Seo Yoon
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.1
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    • pp.1-12
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    • 2023
  • Purpose : This study examined the relationship between oral health management behavior and subjective health perception by using a tool that measures health-related quality of life named EQ-5D. The findings are expected to provide fundamental data for developing diverse programs, including health- and oral-health-related educational media, to ultimately enhance people's health-related quality of life. Methods : Adults over the age of 20 were extracted from the raw materials of the 8th national health and nutrition examination survey conducted in 2019. Among them, 4034 were finally chosen as the study subjects after checking the response distribution of relevant questions and excluding inadequate samples. Variables included general characteristics, health management behavior, oral health management behavior, subjective health perception, and EQ-5D level. Cross-tabulation test, independent t-test, one-way analysis of variance, and linear regression analysis were conducted using SPSS 25.0. Results : EQ-5D, which measures the level of health-related quality of life, was high when the subjects had a medical check-up experience, no experience of unsatisfactory medical service, and did not get an influenza vaccination (p<.001). The quality of life was higher when the subjects received dental inspections, did not require treatment, and used oral care goods (p<.005). Health-related quality of life was also higher when the subjective health level and subjective oral health level were high. Conclusion : Results indicate that subjective health, oral health perception level, and quality of life together were high when people had a regular check-up, did not neglect treatment, and used oral care goods. Considering the findings of this study, check-up programs that are customized for each age group are necessary. Health-related quality of life could be enhanced through the provision of diverse medical services and active efforts to prevent any medical blind spot.

Palaeomagnetism of Cretaceous Rocks in the Ǔisǒng Area, Kyǒngsang Basin, Korea (의성지역 백악기 암석에 대한 고자기 연구)

  • Kim, In-Soo;Lee, Hyun Koo;Yun, Hyesu;Kang, Hee-Cheol
    • Economic and Environmental Geology
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    • v.26 no.3
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    • pp.403-420
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    • 1993
  • The Cretaceous Kyongsang Basin is known to be composed of several tectonic blocks (or subbasins) with each distinct stratigraphic succession. The study area represents a major part of one of these blocks, i. e. the $\check{U}is\check{o}ng$ block. The area is charaterized by a suite of WNW-trending sinistral strike-slip faults as well as a number of ring faults. A total of 292 independently oriented core samples were drilled from 23 sites, covering virtually all the formations of the Cretaceous $Ky\check{o}ngsang$ Supergroup. Alternating field and thermal demagnetization experiments were conducted to reveal the primary magnetization. Due to the homoclinal nature of the strata in the area, it was not possible to make use of the conventional fold test It is, however, believed that the primary remanent components have been obtained from the majority of the formations, considering the similarity of the palaeomagnetic pole positions with those of contemporary strata of other blocks and the existence of antiparallel reversed remanence. It was found neither any significant difference in magnetic declination on each side of the strike-slip faults nor systematic change of magnetic declination with distance from the fault-line. This does not support such a block rotation hypothesis associated with the strike-slip faulting in the area as alleged by some authors. The samples from the outcrops on or near the fault-lines were severely overprinted by the recent magnetic fields regardless of age and lithology. Epithermal Au-Ag-Cu-Pb-Zn mineralizations are known along some fault lines in the area. It is interpreted that these two facts are closely related with fluid circulations along the fracture zones caused by fault activities. In regard to the age of the strata as deduced from the magnetostratigraphic consideration, the $Ch\check{o}mgok$ formation and the lower strata should be older than Barremian or 124 Ma. The age of volcanics of the $Yuch^{\prime}\check{o}n$ Group sampled in this study should be younger than Campanian or 83 Ma.

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Comparative Performance of Broilers Fed Diets Containing Processed Meals of BT, Parental Non-BT Line or Commercial Cotton Seeds

  • Elangovan, A.V.;Mandal, A.B.;Johri, T.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.1
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    • pp.57-62
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    • 2003
  • An effort was made to assess comparative production performance in broiler chickens fed diets containing solvent extracted cottonseed meal (CSM) processed from BT and Parental Non-BT lines. Processed meal of national check and commercial produce cottonseeds were also used for comparison. The free gossypol contents were 0.02, 0.02, 0.44 and 0.03% in meals of BT, Parental Non-BT, national check and commercial produce cottonseeds, respectively. Day-old broiler chicks (n=243) were divided to 27 groups of 9 each. Nine dietary treatments (iso-nitrogenous, 23% CP and iso-caloric, 2,800 kcal ME/kg) were formulated viz., D1 (control, soybean meal-SBM based), D2 and D3 (BT CSM at 10% of diet with and without additional iron), D4 and D5 (non-BT CSM with and without additional iron), D6 and D7 (national check CSM with or without additional iron), and D8 and D9 (commercial produce CSM with or without additional iron at 2 ppm for every 1 ppm of free gossypol, respectively). Each dietary treatment was offered to three replicated groups up to 6 weeks of age. At the end of 6 weeks of age, 10 birds were taken out randomly from each treatment and were sacrificed to study carcass traits, organs' yield and histo-pathological changes in vital organs. The broiler chickens received CSM processed from BT (D2, 1,753 g and D3, 1,638 g) and Parental Non-BT (D4, 1,653 g and D5, 1,687 g) with or without additional Fe grew at same rate as observed in soybean meal (solvent ext.) based diet (D1, 1,676 g). The feed intake and feed conversion efficiency (feed: gain) in these dietary treatments (BT, non-BT line based diets) also did not differ significantly (p>0.05) from control diet. Similar observation was also observed in dietary treatments (D8 and D9) containing solvent extracted cottonseed meal of commercial produce origin. However, a decrease (p<0.05) in body weight gain and feed intake was observed in D6 containing national check CSM with high gossypol content. Addition of Fe in the diet (D7) improved (p<0.05) feed intake and weight gain but not to the extent as observed in diets containing BT, parental non-BT, and commercial produce CSM or control. However, any type of CSM did not affect feed conversion efficiency when fed with or without additional iron. The carcass characteristics in terms of dressing percentage, liver weight and heart weight was not significantly (p>0.05) different between the treatments. The eviscerated yields emanated from diets containing either BT, non-BT or commercial produce were statistically similar to control. However, eviscerated yield of broilers fed national check CSM with or without iron supplementation was lower (p<0.05) than BT cotton with Fe supplementation and commercial produce CSM. The study envisaged that BT, parental non-BT and commercial produce solvent extracted cottonseed meal can be included at 10% in soybean meal based broiler diet replacing soybean meal and rice bran without additional iron.