• 대한간호학회지
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• 제31권2호
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• pp.340-350
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• 2001

The purpose of this study was to investigate the factors influencing social adaptation of chronic mental illness. The subjects of this study were 190 patients, over the age of 20 with chronic mental illness diagnosed by a physician, and living in Seoul, Korea during May, 2000 to December 2000. The instruments for this study were the social adaptation scale by Wallace (1979), the self-esteem scale by Rogenberg (1965), social support scale by ParkJiWon (1985), coping behavior scale by Shirley Zeitlin (1978), self efficacy scale by Sherer et. al (1982), and Rand mental health inventory(1979). The data were analyzed using descriptive statistics, pearson correlation coefficients, and stepwise multiple regression. The results of this study are as follows: 1. The level of social adaptation showed moderate (M=3.43). 2. The social adaptation showed significant positive correlation with self-esteem (r=0.39, p=0.00), self-efficacy (r=0.31, p=0.00), social support (r=0.47, p=0.00), self-productive coping (r=0.14, p=0.05), self-flexible coping (r=0.22, p=0.00), environment-active coping (r=0.21, p=0.00), and environment-flexible coping (r=0.14, p=0.04). The social adaptation showed significant negative correlation with anxiety (r=-0.16, p=0.02), and emotional problems (r=-0.18, p=-0.00). 3. The stepwise multiple regression analysis revealed that the most powerful predictor of social adaptation was social support (21%). A combination of social support, depression, behavioral controllability, self-efficacy, and environmental coping behavior accounted for 39% of the variance in social adaptation in chronic mental illness. From the results of this study, it is suggested to develop and apply a social adaptation training program for chronic mental illness.

• BMB Reports
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• 제44권12호
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• pp.793-798
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• 2011

Recently, pluripotency induction or cellular reprogramming by introducing critical transcription factors has been extensively studied, but has been demonstrated only in vitro. Based on reports that Oct4 is critically involved in transforming neural stem cells into pluripotent cells, we used the lentiviral vector to introduce the Oct4 gene into the hippocampal dentate gyrus (DG) of adult mice. We examined whether this manipulation led to cellular or behavioral changes, possibly through processes involving the transformation of NS cells into pluripotent cells. The Oct4 lentivirus-infused group and the green fluorescent protein lentivirus-infused group showed a similar thickness of the DG and a comparable level of synaptophysin expression in the DG. Furthermore, our behavioral analyses did not show any differences between the groups concerning exploratory activity, anxiety, or memory abilities. This first trial for pluripotency induction in vivo, despite negative results, provides implications and information for future studies on in vivo cellular reprogramming.

• 한국재난정보학회 논문집
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• 제2권1호
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• pp.139-155
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• 2006

Over the past two decades suicide terrorism has become an ever-widening phenomenon. When suicide terrorism was first introduced in the Middle East it seemed that this new phenomenon was invincible and that it might change the innate imbalance between terror groups and their rivalry governments. This did not in fact occur. Looking at history of terrorism, it can be seen that suicide attacks are in actuality a very old modus operandi. However, contemporary suicide terrorism differs from such historical tactics, just as the whole phenomenon of terrorism differs from ancient modes of warfare. Modern suicide terrorism is aimed at causing devastating physical damage. through which it inflicts profound fear and anxiety. Its goal is to produce a negative psychological effect on an entire population rather than just the victims of the actual attack. The relatively high number of casualties guaranteed in such attacks, which are usually carried out in crowded areas, ensures full media coverage. Thus, suicide terrorism, ranks with other spectacular modus operandi such as blowing up airplanes in mid air or the use of Weapons of Mass Destruction as a sure means to win maximum effect. For the purposes of this paper a suicide terror attack is defined as a politically motivated violent attack perpetrated by a self-aware individual (or individuals) who actively and purposely causes his own death through blowing himself up along with his chosen target. The perpetrator's ensured death is a precondition for the success of his mission. The greatest potential risk suicide terrorism may pose in future is if terrorists carry out operations combined with other spectacular tactics such as blowing up airplanes or the use of Weapons of Mass Destruction. Such a combination will increase immensely the death toll of a single terror attack and will have a shocking psychological effect on public moral. At this level suicide terrorism would constitute a genuine strategic threat and would probably be confronted as such. This study portrays a general overview of the modern history of suicide terror activity worldwide, focusing on its main characteristics and the various aims and motivations of the terror groups involved. In addition, This study provides an overview what is to be done to prevent such terrorist attacks.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2008년도 Proceedings of the Convention
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• pp.119-142
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• 2008

Zizyphi Spinosi Semen (ZSS) has been widely used for the treatment of anxiety and insomnia in Korea and China. This experiment was performed to know whether sanjoinine A, one of major alkaloid compounds of ZSS has anxiolytic and hypnotic effects through the GABAergic systems. Our results showed that administration of sanjoinine A increased open arm entries and spent time in open arm in the elevated plus-maze and increased head dips in hole board test. Different from traditional anxiolytic, diazepam, sanjoinine A itself did not decrease locomotor activity and strength level in mice. Furthermore, Sanjoinine A (0.5-2.0 mg/kg) prolonged sleeping time and reduced sleeping latency induced by pentobarbital in a dose-dependent manner similar to muscimol, a $GABA_A$ receptor agonist. Sanjoinine A (0.25-1.0 mg/kg) also increased sleeping rate and sleeping time in the combined administration at the sub-hypnotic dose of pentobarbital and showed synergic effects with muscimol in potentiating sleeping onset and enhancing sleeping time induced by pentobarbital. However, sanjoinine A itself did not induce sleeping at the higher dose. In addition, both of sanjoinine A and pentobarbital increased chloride influx in primary cultured cerebellar granule cells. Sanjoinine A decreased the $GABA_A$ receptor ${\alpha}$-subunit expression and increased ${\gamma}$-subunit expression, and had no effects on abundance of ${\beta}$-subunit in primary cultured cerebellar granule cells, showing different expression of subunits from pentobarbital. In conclusion, sanjoinine A shows anxiolytic-like effects and augments pentabarbital-induced sleeping behaviors through the modification of GABAergic systems. [This work was supported by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (The Regional Research Universities Program/Center for Healthcare Technology Development)].

• 재활간호학회지
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• 제3권2호
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• pp.181-195
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• 2000

The purpose of this study is to find out the effects of personal characteristics, social support, depression, and metamemory on the older adults' memory performances. The subjects of the study consisted of 95 older adults over the age of 60 who are living in Busan. Some data were collected by means of the interview method, using questionnaires for metamemory (MIA questionnaire by Dixon, et al., 1988), and depression(GDS by Yesavage and Sheikl, 1986), social resoueces(Duke university, 1978), family support(Hyun-Sook Kang, 1985). The other data were collected by the testing method on the memory performance such as the immeadiate word recall task, the delayed word recall task, the word recognition task(Elderly Verbal Learning Test by Kyung Mi Choi, 1998), and the face recognition task(Face Recognition Task tool developed by Hye-Sook Min). The results of this study were as follows; 1. The level of metamemory is 3.4 points in the 5 point scale, the grades of the task and the achievement are relatively high and the grades of the change, the control, and the anxiety are relatively low in the sub-concepts. 2. Metamemory have significant relation with age(r=-.44), educational attainment(r=.46), depression(r=-.58), family support(r=.20), social resources(r=.20). 3. The significant variables to predict older adults' metamemory are educational attainment(22%), sex(11%), age (8.3%), depression(4.7%), and illness state(3%). 4. The strong variables to predict memory performances are metamemory, age, depression, social resources, educational attainment, illness state, and limitation of daily living activity related to illness. In conclusion, the enhancement strategies of metamemory and the social support and the prevention or reduction of depression are necessary to increase older adults' memory performances. Ultimately in this respect nurses' roles are very important in developing and performing some intervention programs for old adults' memory improvement, which have significant meanings in the field of nursing science.

• 한국전문물리치료학회지
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• 제27권3호
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• pp.212-219
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• 2020

Background: Although the original version of the health-related quality of life (HRQOL) questionnaires are found to be acceptable, the cross-culturally adapted versions may not be comparable to their original version. Objects: To examine dimensionality and construct validity of two Korean versions of the brief version of the World Health Organization Quality of Life (WHOQOL-BREF) and EuroQOL-5 dimension (EQ-5D) questionnaires. Methods: A total of 77 cancer survivors undergoing palliative rehabilitation programs from two rehabilitation institutes was recruited from April 16, 2018 to June 26, 2019. The WHOQOL-BREF and the EQ-5D were filled out by the various cancer survivors following a particular session of rehabilitation programs. The scores were analyzed with Winsteps Rasch analysis computer program using the rating scale model. Rasch fit statistics were used to determine the dimensionality and the item difficulty calibrations of WHOQOL-BREF and EQ-5D. Results: All items except two, negative feeling, need treatment function and pain prevent activity (mean square [MnSq] = 2.42, 1.82 and 2.51, respectively), were found to be acceptable, while two items of the EQ-5D, anxiety/depression and self-care, were misfit (infit MnSq = 1.65 and 0.38, respectively). Item difficulty calibrations of WHOQOL-BREF match person ability measures (i.e., HRQOL) fairly well. However, the person ability distribution showed obvious ceiling effects for EQ-5D. All items of EQ-5D were appeared to be less challenged in comparison with those of WHOQOL-BREF. Conclusion: Item-level analysis using the Rasch model supports the quality of culturally adapted items used to measure the HRQOL one exception; that is, whether or not to include misfit items as part of the HRQOL measurements. Additionally, cancer survivors undergoing palliative rehabilitation programs appear to have more of a tendency to view the EQ-5D items as being more challenging than the WHOQOL-BREF.

• 동아시아식생활학회지
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• 제25권4호
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• pp.631-642
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• 2015

The purpose of the study was to examine health status and mini nutritional assessment (MNA) according to self-esteem status of elderly in care hospital. The survey was carried out from $13^{th}$ to $31^{st}$ of September, 2014 in five care hospitals. Analysis was performed for 226 subjects. Evaluation criteria included demographics, clinical status, MNA, health-related quality of life (EQ-5D) and self-esteem. The SE I, SE II and SE III groups were divided by self-esteem scores. Data were analyzed one-way ANOVA, Duncan' multiple range test and Pearson's correlation using SPSS 15.0. Education level, religion, dental condition and medical endurance type were significantly different in all groups. Many elderly people were normal BMI ($20.94{\sim}21.67kg/m^2$). Self-esteem significantly increased in order of SE I, SE II and SE III. Mobility, usual activity and anxiety or depression were significantly different in all groups, and EQ-5D of SE II and SE III groups were significantly higher than that of SE I group. Comparison of MNA screening score in elderly patients was as follows : Score for food intake, psychological stress or acute disease, neuropsychological problems, pressure scores or skin ulcer, protein intake, mode of feeding, nutritional status and health status in SE I group were significantly lower than those of SE II and SE III groups. Mobility and drug intake of SE I group were significantly lower than those of SE III groups. Fruit and vegetable intake SE I group were significantly higher than those of SE II and SE III groups. MIS (Malnutrition Indicator Score) was significantly different among the SE I, SE II and SE III groups. We conclude that self-esteem score is positively correlated with protein intake, nutrition status, health status and MIS in elderly care hospital. To improve nutritional status of elderly in care hospitals, systematic nutrition management and self-esteem education program should be implemented.

• 한국보건간호학회지
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• 제19권1호
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• pp.18-29
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• 2005

The purpose of this study was to analyze the smoking behavior and to provide the basic data required to develop a smoking cessation program. The study subjects were 407 industrial workers in Jecheon. The data were collected using a structured questionnaire. The data were analyzed by the SPSS 10.0 system using descriptive statistics, t-test, and Chi-square test. The study results were as follows 1. Current smokers were $64.0\%$, ex-smokers were $19.1\%$. and non-smokers were $16.9\%$. 2. The most common motives of smoking were anger. anxiety, depression. and stress in the workplace. 3. In smoking habits, about $65.1\%$ of the current smokers smoked 11-20 cigarettes/day, and $91.0\%$ had smoked for more than 5 years. The smoking areas of the workplace were outdoor $37.9\%,\;rest\;room\;34.2\%,\; lobby\;23.0\%,\;corridor\;21.4\%,\;and\;office\;8.6\%$. 4. Regarding smoking cessation, $78.2\%$ of current smokers had attempted. The frequency of smoking cessation attempts was 1-3 or less in $67.2\%$ of smokers. The duration of smoking cessation was 1-3 month or less in $61.6\%$ of the smokers. 5. The mean score for smoking knowledge was 17.62, smoking attitude 75.74. and perceived health state 12.27. 6. There were significant differences between smokers and non-smokers 10 smoking attitude (t=5.29, p=0.00), and perceived health state(t=6.47, p=0.00). 7. As a result of the homogeneity test, both types of smoking and perceived health state proved to have significant differences in the change of health state compared with 4 weeks ago'$(x^2=20.26,\;p=0.00)$ and the level of satisfaction of health state in activities of daily living'$(x^2=15.47,\; p=0.05)$. The important findings of this study showed that a smoking cessation program needs to be developed to enhance the negative smoking attitude. to promote the perceived health state through smoking cessation, to encourage the intention of smoking cessation, and to develop strategies of stress management.

• 대한간호학회지
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• 제22권1호
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• pp.68-80
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• 1992

In order to provide data basic to the training of hospice volunteers, this study was carried out to investigate the personal attributes and the Death Orientation of hospice volunteers. 80 hospice volunteers were sampled from those registered on Seoul Catholic Social Service and Korean Association for Volunteers Effort conveniently. Data were gathered from August 16th to October 3rd, 1991. The instrument used for this study was the Death Orientation Questionnaire developed by Thorson and Powell, subjective age and religiosity questionnaire developed by Bell and Batterson, and subjective health criteria developed by Baumann. Data were analyzed using frequency, mean, standard deviation, Chi-square, and t-test by SPSS - program. Result of this study are summarized as follows ; 1. The majority of hospice volunteers perceived younger in their subjective age than their chronological age (65%), Perceived themselves to be healthy subjectively(88.8%), and revealed to have high religiosity score(96.3%) 2. Level of Death Orientation of hospice volunteers was revealed to be moderate.(Mn＝2.06, SD＝0.40, range, 1.45-3.53) Among 25 Death Orientation items, respondents revealed the highest concern over the afterlife (Mn＝3.53, SD＝0.71), revealed the lowest anxiety about not knowing the next world after his or her death(Mn＝1.45, SD＝0.69), and relatively high concern over leaving careful instructions after death (Mn＝2.97, SD＝0.83) Respondents revealed low Death Orientation score(below 1.99) to 12 negative items(2, 3, 5, 6, 7, 9, 14, 17, 18, 19, 20, 22). Thus hospice volunteers seem to be preparing for their own death and shown positive Death Orientation to some items relatively. 3. According to personal attributes (demographic, socioecnomic, and relevant variables) of hospice volunteers, there were no significant statistic differences of Death Orientation score. Thus pre-existing Death Orientation of hospice volunteers and their motive of participation to the hospice service are to be considered important variables influencing the Death Orientation.

• 대한간호학회지
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• 제46권1호
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• pp.29-38
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• 2016

Purpose: The Perinatal Post-Traumatic Stress Disorder Questionnaire (PPQ) was designed to measure post-traumatic symptoms related to childbirth and symptoms during postnatal period. The purpose of this study was to develop a translated Korean version of the PPQ and to evaluate reliability and validity of the Korean PPQ. Methods: Participants were 196 mothers at one to 18 months after giving childbirth and data were collected through e-mails. The PPQ was translated into Korean using translation guideline from World Health Organization. For this study Cronbach's alpha and split-half reliability were used to evaluate the reliability of the PPQ. Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), and known-group validity were conducted to examine construct validity. Correlations of the PPQ with Impact of Event Scale (IES), Beck Depression Inventory II (BDI-II), and Beck Anxiety Inventory (BAI) were used to test a criterion validity of the PPQ. Results: Cronbach's alpha and Spearman-Brown split-half correlation coefficient were 0.91 and 0.77, respectively. EFA identified a 3-factor solution including arousal, avoidance, and intrusion factors and CFA revealed the strongest support for the 3-factor model. The correlations of the PPQ with IES, BDI-II, and BAI were .99, .60, and .72, respectively, pointing to criterion validity of a high level. Conclusion: The Korean version PPQ is a useful tool for screening and assessing mothers' experiencing emotional distress related to child birth and during the postnatal period. The PPQ also reflects Post Traumatic Stress Disorder's diagnostic standards well.