• 제목/요약/키워드: Antimicrobial material

검색결과 263건 처리시간 0.031초

구리 기반 표면코팅 및 산화수에 따른 항균·항바이러스 특성 (Copper-based Surface Coatings and Antimicrobial Properties Dependent on Oxidation States)

  • 고상원
    • 공업화학
    • /
    • 제34권5호
    • /
    • pp.479-487
    • /
    • 2023
  • 구리(Cu)는 저렴한 비용으로 용이하게 도입이 가능하여 다양한 소재 표면에 살균 코팅제로 쓰이고 있다. 자연적 산화 반응이 구리의 효능을 손상시키지 않아 장기간 노출 조건에서도 항균 성능을 유지할 수 있다. 더 나아가 구리 화합물은 그람 음성균 및 그람 양성균 뿐만 아니라, 병원성 효모, 외피 보유 및 외피 미보유 타입의 바이러스에 대해 모두 폭넓은 살균 효과를 보인다. 구리 코팅 표면의 접촉 살균은 구리의 침투로 단백질 변성을 일으키고 세포막 손상으로 뉴클레오티드 및 세포질 등의 내용물이 용출되게 한다. 또한 구리 산화환원 활성에 의한 활성 산소종 생성으로 효소작용을 억제하고 DNA를 파괴하여 세포를 영구적으로 손상시킨다. 구리는 안정한 금속 성질 때문에 나노입자, 이온, 복합물, 합금 등의 여러 형태로 쓰이고 있으며 코팅 방법이 다양하다. 본 총설에서는 구리 이온과 구리 산화물의 대표적인 표면 도입 방법을 살펴보고 구리 산화수에 따른 항균·항바이러스 특성을 다루고자 한다.

Engineering and Economic Evaluation of Production of MgO Nanoparticles using a Physicochemical Method

  • Priatna, Deri;Nandiyanto, Asep Bayu Dani
    • International journal of advanced smart convergence
    • /
    • 제8권4호
    • /
    • pp.26-33
    • /
    • 2019
  • We conducted research to evaluate economically and engineering about the synthesis of Magnesium Oxide, MgO, nanoparticles using physicochemical methods. The method used was economic evaluation by calculating GPM, BEP, PBP, and CNPV. The other method used was engineering perspective. MgO nanoparticles were synthesized by reacting Mg(NO3)2 and NaOH with a mole ratio 1: 2. Mg(OH)2 formed was heated and calcined to remove water content and to oxidation to form MgO. An economic evaluation by calculating GPM and CNPV for the production of MgO nanoparticles on an industrial scale shows that the payback period (PBP) occur in the third year and profits increase each year. Tax variations show that the higher of tax, the lower profits received. When there was an increase of selling prices, the profit was greater. The variable cost used is the price of raw material. When there was an increased in the variable cost price, the payback period was longer and the profits was reduced. The benefit of this research is knowing the industrial production of MgO nanoparticles is beneficial. The function of MgO nanoparticles is a material for the manufacture of ceramics and can be used as an antimicrobial in the water filtration process.

레이온계 여름용 직물에서 매염제 종류에 따른 오배자 염색의 색채발현 및 기능성에 관한 연구 (Coloring Effect and Functionality of Rayon Based Cool Fabrics Treated by Various Mordant and Gallnut Extract)

  • 홍경화
    • 한국의류학회지
    • /
    • 제41권2호
    • /
    • pp.296-305
    • /
    • 2017
  • Gallnuts are known to exert various pharmaceutical properties that include anti-inflammatory, antimicrobial, antioxidant, and detoxifying effects. Gallnut extract is thought to be a particularly safe antimicrobial agent for textile application due to its natural origins. Hence, textiles were dyed with gallnut to develop multi-functional clothing material with no harmful effects. In this study, three kinds of cool touch woven fabrics, each comprised of 100% viscose rayon filament, viscose rayon filament/high absorption & quick dry (polyester) filament, and viscose rayon $filament/tencel^{(R)}$ spun yarn, were prepared and used as substrates for gallnut dyeing to especially develop functional cool touch textiles for summer clothing material. On the other hand, gallnut dyeing was conducted with mordanting with iron, lime or alum, which induced different colors on the dyed textiles. Dyed textiles were then investigated by SEM, FTIR, antibacterial test, and antioxidant test. Subsequently, gallnut dyed textiles indicated excellent antibacterial ability and deodorization activity regardless of mordant species. However, only gallnut dyed textiles mordanted with iron and alum showed significant antioxidant ability. In addition, the dyeing processes impair the cool touch feeling of the textiles by changing the micro structure of the textile surface.

LDPE-나노 ZnO 복합필름의 기능성 및 재질안정성 평가 (A Study on the Functionality and Stability of LDPE-Nano ZnO Composite Film)

  • 이우석;고성혁
    • 한국포장학회지
    • /
    • 제24권1호
    • /
    • pp.27-34
    • /
    • 2018
  • In this work, nano ZnO was introduced into low density poly ethylene (LDPE) composites films with various contents (0, 0.5, 1.0, 3.0 and 5.0 wt%) by melt-extrusion. Their basic properties such as crystallinity, chemical bonds and surface morphology were examined by XRD, FTIR and SEM. XRD patterns and FTIR peaks intensity were increased in proportion to the ZnO contents. SEM images showed well dispersed nano ZnO in LDPE composite films. Antimicrobial functionality of LDPE-nano ZnO composite films was also studied and the presence of nano ZnO resulted in significant improvement of antimicrobial functionality compared to the pure LDPE film. To evaluate influence of nano ZnO on LDPE properties required as packaging material, thermal, mechanical, gas barrier and optical properties of LDPE-nano ZnO composite films were characterized with various analytical techniques including TGA, UTM, OTR, WVTR and UV-Vis spectroscopy. As a result, except optical and mechanical properties of LDPE, no significant effects were found in other properties. Opacity of pure LDPE was greatly increased with increasing concentration of nano ZnO and tensile strength was also improved at 0.5wt% ZnO content.

광화학반응으로 polyallyamine막이 표면에 고정화된 리팜피신-함유 폴리우레탄으로부터 유리되는 리팜피신의 항균 활성에 관한 연구 (Antimicrobial activity of rifampicin released from the rifampicin-containing-polyurethane immobilized on the surface with the polyallyamine membrane using photochemical reaction)

  • 전성민;이규백;김현정;김말남;민병구
    • 대한의용생체공학회:학술대회논문집
    • /
    • 대한의용생체공학회 1997년도 춘계학술대회
    • /
    • pp.31-34
    • /
    • 1997
  • A new method for the prevention of foreign body-associated infections by controlled release of antibiotic was developed. The polyurethane (PU) matrix containing rifampicin was immobilized with hydrophilic photoreactive polyallylamine (PPA) containing azidophenyl groups. The rifampicin release characteristics and the long-lasting antimicrobial activities of the new material was compared with rifampicin-containing PU matrix without PPA membrane. The release rate of antibiotic from rifampicin-containing PU with PPA membrane significantly decreased as the thickness of PPA membrane was increased. The PPA-immobilized rifampicin-containing PU discs immersed in the PBS for 47 days had an efficient antimicrobial activity against both S. aureus and S. epidermidis.

  • PDF

Antimicrobial effect of different brushing frequencies with fluoride toothpaste on Streptococcus mutans and Lactobacillus species in children with fixed orthodontic appliances

  • Peros, Kristina;Mestrovic, Senka;Anic-Milosevic, Sandra;Rosin-Grget, Kata;Slaj, Mladen
    • 대한치과교정학회지
    • /
    • 제42권5호
    • /
    • pp.263-269
    • /
    • 2012
  • Objective: To evaluate the antimicrobial effect of different frequencies of brushing with fluoride toothpaste on the levels of salivary mutans streptococci and lactobacilli in children undergoing fixed orthodontic treatment. Methods: The study included 22 patients scheduled for fixed orthodontic therapy distributed between 2 groups with different hygiene regimes. All the subjects received identical braces, bands, and brackets bonded with the same material. Stimulated saliva samples were obtained before placement of the appliance and at 6, 12, and 18 weeks during the therapy. Saliva samples were cultured on selective microbial agar for the detection of microorganisms. Results: Salivary mutans streptococci were significantly suppressed throughout the experimental period in the group that brushed 4 times a day as compared to the group that brushed twice a day. Salivary lactobacilli were not significantly affected by the frequency of brushing with 0.32% sodium fluoride (NaF) toothpaste. Conclusions: The use of 0.32% NaF-containing toothpaste more than 3 times a day has effective antimicrobial activity on mutans streptococci but not lactobacilli in the saliva of children with fixed orthodontic appliances.

다가알코올로부터 추출된 황금, 아카시아, 한라봉 추출물의 천연 방부시스템 연구 (Study of Natural Preservative System Using the Mixture of Scutellariae radix, Acacia nilotica and Citrus reticulata Extracted from Polyhydric Alcohols)

  • 박성민;이경아;윤미영;김영재;이상화
    • KSBB Journal
    • /
    • 제26권6호
    • /
    • pp.533-537
    • /
    • 2011
  • The aim of this study was to develop a new natural preservative system to improve the weak points of natural polyhydric alcohols together with the efficiency of natural plants as a preservative. Polyhydric alcohols (glyceryl caprylate and ethylhexylglycerin) and antimicrobial plants (S. radix, A. nilotica and C. reticulata) were tested using the disc diffusion method and minimum inhibitory concentration (MIC) method for their antimicrobial activity against the common poultry pathogens, respectively. A study of the preservative efficacy of the cosmetic formulations containing the optimized preservative system demonstrated sufficient preservative efficacy against bacteria and eukaryotic test microbes. These results suggest that the natural preservative system including polyhydric alcohol extracts containing natural plants could be incorporated in cosmetic formulations.

오이풀 뿌리 분획물의 화장품 소재로서의 약리활성 연구 (The research of pharmacological activation for Sanguisorbae Radix Fractions as cosmetic material)

  • 장영아;여신일;이진태
    • 대한본초학회지
    • /
    • 제27권2호
    • /
    • pp.43-46
    • /
    • 2012
  • Objectives : Sanguisorbae Radix(SO) is a plant in the family Rosaceae, which grows widely in open fields Korea. It has been used as traditional medicine for thousands of years, as a treatment for anti-inflammatory and it is widely used for throat infection, tonsilitis, conjuctivitis and lymphadentis. In this study, investigated skin antiaging and anti-bacterial by using SO fractions water, acetone and butanol, chloroform. Methods : The effects of anti-microbial on SO fractions and elastase inhibition activity, collagenase inhibition activity were experimented. Results : 1. The ethyl acetate fraction showed the strongest antimicrobial activity against Staphylococcus epidermidis. 2. The elastase inhibition rate and collagenase inhibition rate of the water fraction of SO was the highest other factions. Conclusions : From the above results, it was confirmed the SO has sufficient potentiality applying itself to industry and also SO can be utilized as antimicrobial natural materials and antiaging cosmetics.

필터와 이온을 이용한 공기살균법 연구동향 (Air sterilization using filter and air ions: A review)

  • 우창규;김학준;김용진;한방우
    • 한국입자에어로졸학회지
    • /
    • 제12권3호
    • /
    • pp.73-80
    • /
    • 2016
  • Bioaerosol inactivation becomes important as people recognize the significance on the health effects of bioaerosols. There are several ways to inactivate such bioaerosols such as antimicrobial filters, UV, etc. For the on-filter-inactivation, proper antimicrobial materials coating should be applied. Recently, air ions are adopted to effectively reduce germ and virus activity. Limitations arise when each method is applied separately. Coating materials can experience chemical instability over time and temperature. Ionizers can generate ozone to prepare high ion concentrations. Combinations of developed techniques to enhance the inactivation efficiency were suggested. Researches on the air sterilization are reviewed and outlook is highlighted. Proper techniques such as combinations of filter material coating and air ion generation can be used to make air quality better for human living.

사상자 추출물의 자돈 병원성 대장균 억제 효과 (The effects of Torilis fructus extracts against enteropathogenic Escherichia coli in Piglets)

  • 홍선화;김옥진
    • 한국동물위생학회지
    • /
    • 제36권4호
    • /
    • pp.283-289
    • /
    • 2013
  • The antibiotic chemotherapy produces sometimes side effects and fails to eliminate bacterial infection. The occurrence of strains resistant to antibiotics would be expected to increase, and it is nowadays important to search for non-antibiotic substances. We are aimed to evaluate the effects of Torilis fructus extracts against enteropathogenic Escherichia coli (E. coli) in Piglets. The piglets were divided with three groups; Negative control group, E. coli-infected positive control group, and the Torilis fructus extracts treated group with E. coli infection. During the study period, we compared clinical signs, weight increase rate, fecal scores, gross findings between the treated group and non treated group. After necropsy, necropsy findings and histopathological findings were conducted with the comparison between the groups. As the results of this study, the Torilis fructus extracts additive showed the effects on the suppression of E. coli-induced lesions. On the basis of this study results, our data suggest that the Torilis fructus extracts additive have the antimicrobial effects. The Torilis fructus extracts additive could be used as the alternative material for antimicrobial feed additives.