• 한국응용과학기술학회지
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• 제17권4호
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• pp.267-272
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• 2000

Dual-actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against gram(+) and gram(-) of 4 strains and a long durability supposing that the stomach and blood.

• 대한수의학회지
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• 제49권2호
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• pp.135-139
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• 2009

Streptomyces (S.) fradiae is a microbe with broad-spectrum antimicrobial activity, isolated from soil. In the present study, antibacterial effects of S. fradiaea against Salmonella (S.) gallinarum was determined. S. fradiae inhibited growing of S. gallinarum in Luria-Bertani media agar. Moreover, ingestion of S. fradiae markedly inhibited mortality of chickens experimentally infected with S. gallinarum. There is no side effect by S. fradiaeon, in safety of chickens and antibiotic material residues in chicken meat. Taken together, S. fradiae have the antibacterial effects against S. gallinarum. Therefore, we concluded that S. fradiae might be a good microbial candidate for treatment or control of fowl typhoid in chickens.

• 한국염색가공학회지
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• 제23권2호
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• pp.146-153
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• 2011

Silver nano-particles have been synthesized by liquid phase reduction method and alcohol reduction process. Silver nano-particles of the size 30 ~ 40 nm were formed successfully by alcohol reduction process. The formation, structure, morphology and size of silver nano-particles have been studied using FE-SEM, TEM, XRD, UV-visible spectroscopy. In particular high dispersion stability of the synthesized silver nano-particles could be obtained by PVP binding. Antibacterial activity of Ag/PET master batch sample made from its nano-silver particles showed excellent antibacterial activity against S. aureus and E. coli.

• 한국축산식품학회지
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• 제18권4호
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• pp.316-321
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• 1998

In this study, we carried out to isolate lactoferrin from Korean native cattle and Holstein cow by batch extraction, ion exchange chromatography, gel filtration, and affinity chromatography. The purity of the isolated lactoferrin was higher than that of lactoferrin purchased from Sigma, when determined by SDS-PAGE and HPLC analysis. Antibacterial activity of E. coli O111 by Korean native cattle lactoferrin was lower than that of Holstein lactoferrin. A minimal inhibitory concentration(MIC) of Korean native cattle lactoferrin and Holstein lactoferrin was 2.75 mg/ ml and 1.5 mg/ml respectively. The lactoferrin hydrolyzate of Korean native cattle exhibited antimicrobial activity at 0.25 mg/ml, whereas that of Holstein cow exhibited antimicrobial activity at 0.12 mg/ml. The antibacterial potency of the hydrolyzate was at least tenfold greater than that of undigeated lactoferrin with strains tested. The effect of hydrolyzate was bactericidal as indicated by rapid loss of viability of E. coli O111.

• 한국섬유공학회:학술대회논문집
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• 한국섬유공학회 2003년도 가을 학술발표회 논문집
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• pp.241-242
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• 2003

Silver has antibacterial property on bacteria of about 650 kinds and has been well known as non-toxic and non-tolerance in natural state. Recently, silver has been applied disinfection and antibacterial property to everyday life as health foods, filter, and exclusion of pollution. Nano-sized silver particle have very small size (〈10nm) and wide surface area per unit volume. PE/PP nonwovens used as back sheet or coverstock of baby diaper, adult diaper, sanitary napkin, and wiper. (omitted)

• Journal of Industrial and Engineering Chemistry
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• 제67권
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• pp.437-447
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• 2018

Visible-light-driven wide bandgap semiconductor photocatalysts were commonly developed via doping or coupling with another narrow bandgap metal oxide. However, these approaches required extra processing. The aim of study was to evaluate the photocatalytic performance of narrow bandgap $WO_x$ nanoparticles. A mixture of $WO_2$ and $WO_3$ nanoparticles were synthesized using solution precipitation technique. The photodegradation of RhB by these nanoparticles more effective in UV light than in visible light. In antibacterial susceptibility assay, $WO_x$ nanoparticles demonstrated good antibacterial against Gram-positive bacteria. The cell wall of bacterial was the main determinant in antibacterial effect other than $W^{4+}/W^{6+}$ ions and ROS.

• 대한약침학회지
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• 제25권2호
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• pp.101-105
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• 2022

Objectives: This study aims to determine the Fractional Inhibitory Concentration Index (FICI) of combinations of Melastoma malabathricum leaf fraction with ciprofloxacin or gentamicin against pathogenic bacteria, Escherichia coli, Staphylococcus aureus, and Bacillus cereus, isolated from Diabetic Foot Ulcer (DFU) patients. Methods: We tested concentrations of 45%, 55%, 65%, and 75% of gentamicin and ciprofloxacin using dilution and agar diffusion methods. The combination of M. malabathricum leaf extract with these antibiotics was tested in vitro against all three bacteria. Results: The combination of M. malabathricum leaf extract and ciprofloxacin gave a FICI value of 0.5, indicating synergistic antibacterial activity against the test bacteria. Conclusion: The results show that the antibacterial effect of a combination of high doses of the leaf extract with either antibiotic is greater than that of the leaf extract and the antibiotics in single use.

• 한국식품영양학회지
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• 제24권4호
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• pp.708-712
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• 2011

This study was focused on the determination of antibacterial activity of $Scutellaria$ $baicalensis$ extract against antibiotic resistant bacteria($Salmonella$ Enteritidis, $Staphylococcus$ $aureus$ and enteroaggregative $E.$ $coli$). Extract of $Scutellaria$ $baicalensis$ were tested for antibacterial activity by paper disc methods. The $Scutellaria$ $baicalensis$ extract in 0.1 g/$m{\ell}$ and 0.2 g/$m{\ell}$ showed a significant antibacterial activity against antibiotic resistant bacteria. Minimum inhibitory concentration (MIC) of $Scutellaria$ $baicalensis$ extract were appeared to 2,048 ${\mu}g/m{\ell}$ at $S.$ Enteritidis, $S.$ $aureus$ and enteroaggregative $E.$ $coli$. Finally, the growth incubation curve was determined using $Scutellaria$ $baicalensis$ extract against $S.$ Enteritidis, $S.$ $aureus$ and enteroaggregative $E.$ $coli$. The growth of $S.$ Enteritidis was significantly inhibited within 10 hours by the addition of at least 10,000 ppm of $Scutellaria$ $baicalensis$ extract. The 10,000 ppm of $Scutellaria$ $baicalensis$ extract retarded the growth of $S.$ $aureus$ and enteroaggregative $E.$ $coli$ more than 10 hours. In conclusion, $Scutellaria$ $baicalensis$ extract might be useful to control antibiotic resistant bacteria $in$ $vitro$.

• Restorative Dentistry and Endodontics
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• 제38권1호
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• pp.36-42
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• 2013

Objectives: This study evaluated the antibacterial effect and mechanical properties of composite resins ($L_{CR}$, $M_{CR}$, $H_{CR}$) incorporating chitosan with three different molecular weights (L, Low; M, Medium; H, High). Materials and Methods: Streptococcus (S). mutans 100 mL and each chitosan powder were inoculated in sterilized 10 mL Brain-Heart Infusion (BHI) solution, and was centrifuged for 12 hr. Absorbance of the supernatent was measured at $OD_{660}$ to estimate the antibacterial activities of chitosan. After S. mutans was inoculated in the disc shaped chitosan-containing composite resins, the disc was cleansed with BHI and diluted with serial dilution method. S. mutans was spread on Mitis-salivarius bacitracin agar. After then, colony forming unit (CFU) was measured to verify the inhibitory effect on S. mutans biofilm. To ascertain the effect on the mechanical properties of composite resin, 3-point bending and Vickers hardness tests were done after 1 and 3 wk water storage, respectively. Using 2-way analysis of variance (ANOVA) and Scheffe test, statistical analysis was done with 95% significance level. Results: All chitosan powder showed inhibition effect against S. mutans. CFU number in chitosan-containing composite resins was smaller than that of control resin without chitosan. The chitosan containing composite resins did not show any significant difference in flexural strength and Vickers hardness in comparison with the control resin. However, the composite resin, $M_{CR}$ showed a slightly decreased flexural strength and the maximum load than those of control and the other composite resins $H_{CR}$ and $L_{CR}$. Conclusions: $L_{CR}$ and $H_{CR}$ would be recommended as a feasible antibacterial restorative due to its antibacterial nature and mechanical properties.

• 펄프종이기술
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• 제45권3호
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• pp.45-51
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• 2013

We developed a new antibacterial material, a non-woven fabric, a sulfur solution, and a new adhesive system to manufacture a new type of functional hybrid corrugated board in previous studies. Based on experimental data, the prototypes of functional hybrid corrugated boards were manufactured and their physical properties and functionalities, including antibacterial property and the freshness maintenance of sweet persimmon, were measured in this study. The functional hybrid corrugated board could be manufactured in the actual process with linerboards, non-woven fabrics, and other materials without any troubles, and was strong enough to be used as a packaging box for agricultural products. The antibacterial property of the hybrid corrugated board showed a value high enough to eliminate bacteria, which could deteriorate the sweet persimmons. Based on appearance observations, weight loss and firmness measurements, the freshness of sweet persimmons in the functional hybrid corrugated board was maintained better than it was in the conventional corrugated board.