• Title/Summary/Keyword: Antibacterial rate

Search Result 252, Processing Time 0.023 seconds

Development of Resources for Functional Food and Biological Activity of Lentinus edoes mycelium (표고버섯 균사체의 생리활성과 기능성식품 소재 개발)

  • Kim, Soo-Min;Kim, Eun-Ju
    • The Korea Journal of Herbology
    • /
    • v.26 no.2
    • /
    • pp.25-30
    • /
    • 2011
  • Objectives : This study was carried out to investigate an antioxidant ability, the change of antioxidant ability, antimicrobial activity and anticancer in functional meat ball and sausage prepared from Lentinus edoes mycelium and texturized soy protein. Methods : This experiments was carried out to investigate antioxidant ability(TBARS, DPPH, SOD-like ability), antibacterial activity and anticancer ability using sarcoma 180 extracts from Lentinus edoes mycelium. Result : Anticancer ability of Lentinus edoes mycelium showed a 28% survival rate and 63% of inhibition rate of tumor, which showed $1.30{\pm}0.4g$ of tumor weight. These results revealed an effective Lentinus edoes mycelium resources as anticancer sources. After heating peoducts prepared from Lentinus edoes mycelium, these products doesn't showed difference between after heating and before heating in measuring of SOD-like activity and DPPH. In DPPH experiment, ethanol extracts showed a high DPPH value as 90.85%, but hot water extracts showed 82.14% in DPPH value. Conclusion : In conclusion, it is very useful resources for preparing functional food on the basis of results from antioxidant(TBARS, DPPH, SOD-like ability), antibacterial activity and anticancer ability using sarcoma 180.

Studies on theEfficacy of Machili Cortex in the Digestive System (한국후박(韓國厚朴)(Machili Cortex)의 소화기계(消化器系)에 대한 약효연구(藥效硏究))

  • Lee, Byoung-Joo;Chung, Myung-Hyun
    • Korean Journal of Pharmacognosy
    • /
    • v.25 no.3
    • /
    • pp.278-292
    • /
    • 1994
  • This study was attempted to investigate the effect of Machili Cortex extract(Machilus thunbergii Sieb. et Zucc. ) on digestive system in experimental animals. EtOH and MeOH extracts(E.E. and M.E.) were found to inhibit the charcoal transport rate in the small intestine of mice. E.E. exhibited the inhibition of spontaneous movement(motility) and tension in the ileum and colon strips of rabbit, and these actions were inhibited by action of acetylcholine. E.E. and M.E. given intraduodenaly(i.d.) exhibitied the significant decrease of gastric acid secretion in pylorus-ligated rats. E.E. and M.E. inhibited the formation of some experimental gastric ulcers(pylorus ligation-ulcer i.d., indomethacin-induced ulcer p.o. and aspirin-induced ulcer p.o. ) in rats, which are considered to relate to a protective action. E.E. and M.E. caused remarkable increase of bile excretion, compared with normal-control group, when adminstered through i.d., i.v. and p.o. The antibacterial activity against several intestinal microorganisms and other bacteria in vitro test was observed in the administration of E.E. and M.E.

  • PDF

The Dyeing Properties and Antibacterial Activity of Fabrics Dyed with Camomile Extract (캐모마일 추출액 염색직물의 염색성 및 항균성)

  • Park Young-Hee
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.29 no.8 s.145
    • /
    • pp.1188-1195
    • /
    • 2005
  • The effects on the dyeing properties and antibacterial activity of fabrics dyed with camomile extract were analyzed. As the results obtained, the surface color of all the dyed fabric was tinged with the yellow of the bright color tone. In the test results of durability, the durability to sunlight of the dyed fabric of both cotton and silk showed from 2nd grade to 3rd grade. The durability to laundry of the dyed fabric of both cotton and silk showed relatively higher grade of 4th-5th. The durability to synthetic sweat of all the fabrics except fer the dyed fabric mordanted with $CuSO_4{\cdot}5H_2O$ showed the relatively good result of 3rd- 5th grade. The durability to friction and dry cleaning of all the dyed fabrics showed the excellent result of 4th-5th grade. In the test results of antibiosis, the dyed fabric of cotton showed the decrease rate of $50\%$ to Staphylococcus aureus and the decrease rate of $70\%$ to Klebsiella pneumoniae. The dyed fabric of silk showed the significant effect with Microscopic growth to the mold bacillus Aspergillus niger.

The Use Possibility as a Dyestuff of Scutellaria Baicalensis Extract (황금(黃芩)의 천연염재로의 이용가능성에 관한 연구)

  • Bai, Sang-Kyoung
    • Fashion & Textile Research Journal
    • /
    • v.11 no.4
    • /
    • pp.667-671
    • /
    • 2009
  • The use possibility as a dyestuff of Scutellaria baicalensis was investigated. The optimum conditions were evaluated when silk fabrics were dyed by Scutellaria baicalensis extract. The colorants of Scutellaria baicalensis were extracted better in water than methanol. The optical dyeing concentration was 80%(v/v), dyeing temperature was $80^{\circ}C$, dyeing time was 60minites, dyeing repetition was 2 turns. A Post-mordant method showed higher K/S value than premordant one, especially post-Fe appeared the highest value and post-Cr was second. Surface color was all Y. The color fastness was very good at the second repetition of no mordanted silk fabrics, all mordant fabrics were not improved the colorfastness. The antibacterial activity showed at Staphylococcus aureus tested specimen that bacterial reduction rate was 99.7%.

The Anti-Bacterial Properties of LTP Crystallized Glass by Ag Ion Exchange (LTP계 결정화유리의 Ag이온교환에 따른 항균특성)

  • 권면주;윤영진;강원호
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.3 no.3
    • /
    • pp.183-188
    • /
    • 2002
  • Antibacterial glass ceramics composed of $5Li_2O{\cdot}36CaO{\cdot}20TiO_2{\cdot}27P_2O_5$ were Prepared. After ion exchange in the $AgNO_3$solution, crystallization phases were $AgTi_2(PO_4)_3$, $LiTi_2(PO_4)_3$ and $Ca_3(PO_4)_2$. In case of ion exchange, the crystallization phases started to be transformed from $LiTi_2(PO_4)_3$ to $AgTi_2(PO_4)_3$in 0.5 mole $AgNO_3$ solution and the transformation was almost completed in 1.0 mole. ion exchange rate of glass-ceramics powder, considering ion exchange time, was more fast than that of bulk. The bacteriostatic effect of the glass-ceramics on Staphyloroccus aureus and Salmonella typhi bacteria was more excellent than that of glass when the crystallization phase was transformed from LTP to AgTP.

  • PDF

판상형 산화아연의 합성 및 응용에 관한 연구 동향

  • Jang, Ui-Sun
    • Ceramist
    • /
    • v.20 no.4
    • /
    • pp.55-73
    • /
    • 2017
  • As one of the most versatile semiconductors, zinc oxide (ZnO) with one-dimensional (1-D) nanostructures has been significantly developed for the application of ultraviolet (UV) lasers, photochemical sensors, photocatalysts, and so on. Such 1-D nanowires could be easily achieved due to the anisotropic growth rate along the [0001] direction. However, such typical growth habit leads to decrease the surface area of the (0001) plane, which plays a central role in not only UV lasing action but also photocatalytic reaction. This fact lead us to develop ZnO crystal with enhanced polar surface area through crystal growth control. The purpose of this review is to provide readers a simple route to plate-type ZnO crystal with highly enhanced polar surfaces and their applications for UV-laser, photocatalyst, and antibacterial agents. In addition, we will highlight the recent study on pilot-scale synthesis of plate-type ZnO crystal for industrial applications.

Synthesis and Antibiotic Activities of CRAMP, a Cathelin-related Antimicrobial Peptide and Its Fragments

  • 하종명;신송엽;강신원
    • Bulletin of the Korean Chemical Society
    • /
    • v.20 no.9
    • /
    • pp.1073-1077
    • /
    • 1999
  • CRAMP, a 37-amino acid cationic antimicrobial peptide was recently deduced from the cDNA cloned from mouse femoral marrow RNA. In order to investigate the structure-activity relationship and functional region of CRAMP, CRAMP and its 18-mer overlapping peptides were synthesized by the solid phase method. CRAMP showed broad spectrum antibacterial activity against both Gram-positive and Gram-negative bacterial strains (MIC: 3.125-6.25 μM) but had no hemolytic activity until 50 μM. CRAMP was found to have a potent anticancer activity (IC50: 12-23 μM) against two human small cell lung cancer cell lines. Furthermore, CRAMP was found to display faster bactericidal rate in B. subtilis rather than E. coli in the kinetics of bacterial killing. Among 18-meric overlapping fragment peptides, only CRAMP (16-33) displayed potent antibacterial activity (MIC: 12.5-50 μM) against several bacteria with no hemolytic activity. Circular dichroism (CD) spectra anal-ysis indicated that CRAMP and its analogues will form the amphipathic α-helical conformation in the cell membranes similar to other antimicrobial peptides, such as cecropins and magainins.

Antibacterial and Antibiofilm Activities of Alnus japonica Stem Extract against Porphyromonas gingivalis (Porphyromonas gingivalis에 대한 오리나무 줄기 추출물의 항균활성 및 생물막 형성 억제 효과)

  • Kim, Hye Soo;Cho, Soo Jeong
    • Journal of Life Science
    • /
    • v.29 no.12
    • /
    • pp.1386-1392
    • /
    • 2019
  • This study investigated the potential of dye plants as natural oral health products. The antibacterial activity of ethanol stem extracts of A. japonica, R. verniciflua Stokes, G. jasminoides, D. morbifera, P. amurense Rupr., and S. japonica against P. gingivalis KCTC 5352, S. mutans KCTC3065, S. downei KCTC3634, S. sanguinis KCTC3284, and S. gordonii KCTC 3286 was confirmed. Among the stem extracts from 6 dye plants grown in Korea, ethanol extract from A. japonica stem (1 mg/disc) showed the highest antibacterial activity against P. gingivalis KCTC5352. The A. japonica stem extracts showed antibacterial activity similar to chlorhexidine, which was used as a positive control. The MIC and MBC of P. gingivalis KCTC5352 were 0.4 mg/ml and 0.6 mg/ml, respectively. The biofilm production rate and cell growth of P. gingivalis KCTC5352 in the cultures treated with 0.2-2.0 mg/ml of A. japonica extract were significantly decreased in a concentration-dependent manner. In addition, the mRNA expression of the superoxide dismutase and fimA associated with fimbriae formation in these cultures was suppressed, also in a concentration-dependent manner. Based on these results, it is concluded that A. japonica stem extracts can be used as an oral health product derived from natural materials, as demonstrated by its antibacterial action against and inhibition of biofilm formation of P. gingivalis KCTC5352.

Development of Antibacterial Hood and Filter for Medical Powered Air Purifying Respirators (PAPR) (의료용 전동공기청정호흡기(PAPR)용 항균성 후드 및 필터 개발)

  • Eunjoo Koh;Nahyun Cho;Yong Taek Lee
    • Membrane Journal
    • /
    • v.33 no.6
    • /
    • pp.398-408
    • /
    • 2023
  • This work developed a hood and filter for antibacterial protective clothing for medical powered air purifying respirators (PAPR) that can be used in medical settings and quarantine against infectious diseases such as Zika virus, Middle East respiratory syndrome (MERS), and coronavirus disease-19 (COVID-19). The hood material of the protective clothing was made of polypropylene spunlace nonwoven fabric (SFS) was used for withstand wind pressure and external physcial pressure. Forthermore, in order to reduce the user's risk of infection, phytoncide-based materials were used on the outer-surface of the hood to achieve a 99.9% antibacterial effect, and the inner-surface were treated with hydro-philic materials to improve absorbency by 25%. In addition to evaluating the artificial blood penetration resistance, dry mi-croorganism penetration resistance, wet bacteria penetration resistance, and bacteriophage penetration resistance required for medical protective clothing hoods, it received a passing evaluation of levels 2-6. Meanwhile, as a result of evaluating the performance of the antibacterial treated spunlace high efficiency particulate air (HEPA) filter, excellent antibacterial properties, dust removal rate, and differential pressure effect were confirmed. All performance evaluations were conducted by an accredited certification body in accordance with the medical PAPR certification standards.

Antibacterial and anti-inflammatory effects of Platycodon grandiflorum extracts (도라지 추출물의 항균작용 및 항염작용)

  • Kim, Jung
    • Journal of Digital Convergence
    • /
    • v.12 no.3
    • /
    • pp.359-366
    • /
    • 2014
  • This study investigated the impact on S. mutans와 C. albicans in order to reveal the antimicrobial activity of Platycodon grandiflorum extracts. In addition, it examined NO generation inhibition rate in accordance with the extract concentration from Raw 264.7 cell in order to find out anti-inflammatory activation. As for the study materials, domestically made 100% Platycodon grandiflorum powder was utilized. As for the experimental strain, S. mutans KCTC 3065 and C. albicalns KCTC 7965 were utilized. Consequently, this study obtained the following results. Growth inhibition rate of S. mutans became significantly higher with higher concentration of Platycodon grandiflorum extracts. Growth inhibition rate of C. albicans became significantly higher with higher concentration of Platycodon grandiflorum extracts. NO generation inhibition rate was found to be 29.2% and 26.1% respectively when adding Platycodon grandiflorum extract with the concentration of 10 and $20{\mu}g/ml$ in Raw 264.7 cells. These results mean that Platycodon grandiflorum could be leveraged as antimicrobial and anti-inflammatory substance.