• Journal of the Korean Institute of Telematics and Electronics
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• v.4 no.2
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• pp.3-15
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• 1967

In the design of a portable Gamma-ray transistorized steel pipe thickness gauge, a pulse height discriminator and an anti-coincidence circuit could be eliminated by using a thin, less than 1/2inch, NaI(Tl) scintillation crystal in the detecting probe. This method could provide an economic design and fabrication of a gamma-ray back-scattering gauge allowing allmost the same accuracy and stability compared with the exsisting method. A gauge had been designed and fabricated with the above method and its accuracy was experimentall tested for the 200$^{\circ}C$ high temperature steel pipes. The result showed that the thermal drift was less than y percent which was acceptabel in the practical applications.

• Journal of the Optical Society of Korea
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• v.14 no.4
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• pp.431-437
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• 2010

A stack of gradient-index (GRIN) rod lenses cannot be used for coherent anti-Stokes Raman scattering (CARS) microendoscopy for insertion to internal organs through a surgical keyhole with minimal invasiveness. That's because GRIN lens has large amount of inherent chromatic aberrations in spite of absolutely requiring a common focus for pump and Stokes beam with each frequency of ${\omega}_p$ and ${\omega}_S$. For this endoscopic purpose, we need to develop a long slender probe-type objective, namely probe-type microscope objective (PMO). In this paper, we introduce the structure, the working principle, and the design techniques of PMO which is composed of a probe-type lens module (PLM) and an adaptor lens module (ALM). PLM is first designed for a long slender type and ALM is successively designed by using several design parameters from PLM for eliminating optical discords between scanning unit and PLM. A combined module is optimized again to eliminate some coupling disparities between PLM and ALM for the best PMO. As a result, we can obtain a long slender PMO with perfectly diffraction-limited performance for pump beam of 817 nm and Stokes beam of 1064 nm.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.3
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• pp.195-203
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• 2002

In the engine room and the aft part areas of the ship, there exist so many tank structures contacting with fresh water or sea water or oil. If these structures exhibit excessive vibrations during the sea trials, it takes a lot of cost, time and effort to improve vibration situation because the reinforcement work requires emptying the fluid out of the tanks, additional welding and special painting. It is therefore very important to predict a precise vibration characteristics of the tank structures at the design stage, however it is not easy to estimate vibration characteristics of the structures because of difficulties for accurate evaluation of the added (or virtual) mass effect due to the fluid inside the tank. In this paper, numerical and experimental approaches have been performed to present same fundamental data necessary for anti-vibration design of tank structures contacting with fluid, by investigating vibration behaviors of rectangular tank structure for various water depths.

• Journal of IKEEE
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• v.3 no.1 s.4
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• pp.69-78
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• 1999

In this paper, direct conversion receiver was designed to even harmonic anti-paralled diode pair ring mixer. Using a second harmonic component of LO instead of LO signal and RF signal are mixed by SHP(Sub Harmonic Pumped) mixer with anti-parallel diode pair. Canceling the harmonics of LO signal in ring mixer, SHP mixer using anti-parallel diode pair could mostly reduce the radiation of LO signal through a input port the most, good isolation characteristic, and low spurious characteristic by LO signal was shown over broad band. The produced SHP mixer showed LO/IF, RF/IF and LO/RF isolation was 24.6dB,36.2dB and 22.5dB respectively. And conversion loss was measured 15.6dB, IF output -35.6dBm with -20dBm RF input and 5.5dBm LO signal. 1dB compression point of If signal, in respect to RF signal, was found at the 0dbm RF signal.

• Biomolecules & Therapeutics
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• v.19 no.3
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• pp.331-335
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• 2011

In this study, we determined the anti-inflammatory activity and mechanism of action of a hexane fraction (hWRF) obtained from white Rosa hybrida flowers by employing various assays such as quantitative real-time PCR, Western blotting, and Electrophoretic-Mobility Shift Assay (EMSA). The results revealed that the hWRF had excellent anti-inflammatory potency by reducing inflammatory repertoires, such as inducible nitric oxide synthase (iNOS), interleukin-$1{\beta}$, and cyclooxygenase-2 (COX-2) in RAW264.7 cells when stimulated with lipopolysaccharide (LPS), a pro-inflammatory mediator. The reduction of nitric oxide (NO) release from RAW 264.7 cells supported the anti-inflammatory effect of hWRF. Interestingly, hWRF effectively inhibited LPS-mediated nuclear factor-${\kappa}B$ (NF-${\kappa}B$) p65 subunit translocation into the nucleus and extracellular signal-regulated kinase (ERK)1/2 phosphorylation, suggesting that hWRF anti-inflammatory activity may be based on inhibition of the NF-${\kappa}B$ and MAPK pathways. Based on the findings described in this study, hWRF holds promise for use as a potential anti-inflammatory agent for either therapeutic or functional adjuvant purposes.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.42 no.1
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• pp.76-81
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• 2014

Military helicopter is exposed to the enemy gun firing due to the low altitude flight of contour flight, hovering & nap of the Earth flight, therefore it has the high possibility to be exploded by the gun firing. Recently the Anti-ballistic requirement is required to get the high level of safety from gun firing in required operational capability. The first military utility helicopter of SURION has the Anti-ballistic requirement and explosion proof. In order to meet the requirement, OBIGGS is adopted for the first time in KUH. It is proven that Anti-Explosion capability is satisfied to requirement for improving vent system which was insufficiently designed in development period and related to Anti-explosion.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.436-436
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• 2011

Recently, spintronic devices with submicron structures are widely investigated to take advantage of their unique micromagnetic properties. In this work, we study the temperature dependence of exchange bias in bilayer anti-dot arrays made by depositing Co (40 nm)/Ni (5 nm) ferromagnetic bilayer on Si substrate to form anti-dot arrays with a diameter $1{\mu}m$. The anti-dot patterning was done only for the upper Co layer, while the Ni underlayer was kept unperforated. The temperature dependences of magnetoresistance (MR) and exchange bias were studied along magnetic easy and hard axes. The in-plane MR measurements were performed using a physical-property measurement system (PPMS ; Quantum Design Inc.) at various temperatures. The standard in-line four-point probe configuration was used for the electrical contacts. As temperature was varied, the MR data were obtained in which in-plane field (H=3 kOe) was applied in the directions along the hard and the easy axes with respect to the lattice plane. The temperature dependences of magnetic anisotropy and exchange bias were also studied along the magnetic easy and hard axes. As temperature decreases, the single peak splits into two peaks. While no exchange bias was observed along the magnetic easy axis, the exchange bias field steadily increased with decreasing temperature along the magnetic hard axis. These results were interpreted in connection with the magnetic anisotropy and the effect of the anti-dots in pinning domain wall motion along the respective direction.

• Journal of the Society of Naval Architects of Korea
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• v.56 no.6
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• pp.550-558
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• 2019

The roll motion of a general vessel, which is more influenced by resonance as compared to other motions, adversely affects the passenger and hull. Therefore, reducing the roll motion through an anti-rolling system is critical, and most ships use various devices such as anti-rolling tanks, bilge keels, and fin stabilizers to accomplish this. In this study, a simplified model is developed for the application of an anti-rolling device for unmanned semi-submersible vessels. The applied anti-rolling device is installed on the stern and stem of a ship using a pair of servo motors with added weight, and the motor is controlled through the Arduino. The moment of the motor is designed and implemented based on a mathematical model such that it is calculated through the restoring force according to the heel angle of the ship. The performance of the proposed system was verified by utilizing the roll damping coefficient calculated by the free-roll decay test and logarithmic decrement method and was validated by a towing tank test. The system is expected to be used for unmanned vessels to perform sustainable missions.

• Korean Journal of Oriental Medicine
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• v.17 no.3
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• pp.77-85
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• 2011

Objectives : The purpose of this study was to develop a simulator which can analyze the anti-inflammatory effects of medical herbs based on e-cell concerning p38 MAPK signal pathway. Methods : We collected data concerning medical herbs with anti-inflammatory effects and the active compounds to provide as a fundamental databse and to validate the newly developed algorithm. At this time, we used the target database as pubmed and gathered the data by data mining tool, pathway studio. Also we have developed the web-based search system for confirming database related to anti-inflammation. We researched the mechanism of actions of proteins in p38 MAPK signal pathway when active compound has been inserted into the network. We reduced total network into TAK-MKK3-p38 and made the two types of mathematical model about active compounds' interaction. Results & Conclusion : We constructed the database which have 69 cases of medical herbs, 71 cases of active compounds, about 8,000 cases of URL(Uniform Resource Locator) related to papers and reports. We designed the ordinary differential equations for response of TAK, MKK3, p38 in e-cell's cytosol and nucleus. We used this formular as measure whether an active compound of medicinal plants which is inputted by an user would have an anti-inflammation effects. We developed the visualization program which could show the change of concentration over time.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.1
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• pp.74-86
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• 2017

Objectives : This study aimed to assess the scientific evidence for the use of Hwanglyeonhaedok-tang, a traditional herbal formula, in the treatment of rhinitis, and prepare the basis for the investigational new drug application by analyzing the experimental studies. Methods : Ten electronic databases were searched up to December, 2016 without language limitation. Experimental studies on the anti-inflammatory and anti-allergic effects of Hwanglyeonhaedok-tang against rhinitis were included. We extracted data about study design, characteristics of intervention, outcomes, and pharmacological effects from the included studies and summarized them. Results : Eight hundred and thirty-three potentially relevant studies were identified, of which 18 experimental studies met our inclusion criteria. Of 18 included studies, 5 had conducted cell viability test, and all studies had reported that Hwanglyeonhaedok-tang was non-cytotoxic. Hwanglyeonhaedok-tang exhibits anti-inflammatory effect by regulating the inflammation-related cytokines including nitric oxide(NO), prostaglandin $E_2(PGE_2)$, interleukin-6(IL-6), and tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ in vitro and in vivo. Hwanglyeonhaedok-tang exhibits anti-allergic effect by suppressing eosinophil, and histamine levels. Hwanglyeonhaedok-tang helps in the recovery of nasal mucous membrane by supressing goblet cells, heat shock protein 70, and substance P. Conclusions : This study suggests that Hwanglyeonhaedok-tang has the potential to be developed as therapeutic agent for rhinitis. Further experimental and clinical studies needed to be performed to prove the safety and efficacy.