• Bulletin of the Korean Chemical Society
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• 제28권12호
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• pp.2235-2240
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• 2007

3-Aryloxy methyl-4-(N-pyrazin-2'yl carboxamido)-5-mercapto-1,2,4-triazoles (3a1-a14) were prepared starting from potassium dithio carbazinates (2a1-a14). These triazoles were then employed in the synthesis of 3-aryloxy methyl-4-(N-pyrazin-2'yl carboxamido)-5-hydrazino-1,2,4-triazoles (4a1-a14). All the newly synthesized compounds were characterized by analytical, IR, NMR spectral studies. The compounds were screened for their antibacterial, antifungal, anti-inflammatory and analgesic properties. Most of the compounds have shown significant antifungal activity while few have shown excellent anti-inflammatory and analgesic activity. An attempt is made to study the structure activity relationship (SAR).

• Biomolecules & Therapeutics
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• 제25권4호
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• pp.345-353
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• 2017

Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used to produce recombinant proteins at low production cost. However, several technical issues hinder large-scale production of anti-cancer vaccines in plants. The present review covers design strategies to enhance the immunogenicity and therapeutic potency of anti-cancer vaccines, methods to increase vaccine-expressing plant biomass, and challenges facing the production of anti-cancer vaccines in plants. Specifically, the issues such as low expression levels and plant-specific glycosylation are described, along with their potential solutions.

• 한국소음진동공학회논문집
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• 제12권9호
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• pp.661-667
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• 2002

With the increase of storage density, high rotational speed and high access technologies in optical disk drive, mechanical issues, mainly noise and vibration, become critical. Up to now the researches of rubber mount for anti-vibration focused on how to calculate the static and the dynamic stiffness of rubber mount and loaned out consideration of the dimensional tolerance of rubber mount for anti-vibration. This paper presents the effects of dimensional tolerance of rubber mount for anti-nitration on the dynamic characteristics of optical disk drive by finite element analysis and dynamic test. The relation between dimensional tolerance and dynamic characteristics of optical disk drive is observed and discussed.

• 제어로봇시스템학회논문지
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• 제19권10호
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• pp.867-872
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• 2013

Many practical processes in industry have nonlinearities of some forms. One commonly encountered form is actuator saturation which can cause a detrimental effect known as integrator windup. Therefore, a strategy of attenuating the effects of integrator windup is required to guarantee the stability and performance of the overall control system. In this paper, optimal tuning of a PID (Proportional-Integral-Derivative) controller with an anti-windup scheme is presented to enhance the tracking performance of the PID control system in the presence of the actuator saturation. First, we investigate effective anti-windup schemes. Then, the parameters of both the PID controller and the anti-windup scheme are optimally tuned by an EA (Evolutionary Algorithm) such as the IAE (Integral of Absolute Error) is minimized. A set of simulation works on two high-order processes demonstrates the benefit of the proposed method.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 Asia Navigation Conference
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• pp.176-183
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• 2006

A novel intelligent anti-collision decision-making supporting system is addressed in this paper. To obtain precise anti-collision information capability, an innovative neurofuzzy network is proposed and applied. A fuzzy set interpretation is incorporated into the network design to handle imprecise information. A neural network architecture is used to train the parameters of the Fuzzy Inference System (FIS). The learning process is based on a hybrid learning algorithm and off-line training data. The training data are obtained by trial manoeuvre. This neurofuzzy network can be considered to be a self-learning system with the ability to learn new information adaptively without forgetting old knowledge. This supporting system can decrease ship operators' burden to deal with bridge data and help them to make a precise anti-collision decision.

• 대한조선학회 특별논문집
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• 대한조선학회 2011년도 특별논문집
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• pp.63-69
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• 2011

Exhaust gases of a vessel from a main engine, a diesel generator and an incinerator contain very harmful substances like soot, $SO_2$ and NOx. Careful design of funnel shape is required to prevent those harmful exhaust gases from influencing on accommodation and a fan room. Meanwhile, the exhaust gases are also hot enough to damage electronic devices like radar. Therefore the funnel design should be considered so that electronic devices are not directly exposed to the exhaust gas in the strong stern wind. This study may propose guidelines of optimum design criterion for the anti-thermal damage design of the electronic devices and anti-recirculating design of harmful exhaust gas near the accommodation. From CFD analyses, we can understand that the major factors affecting the exhaust gas dispersion are the large scale mixing by separation vortices and the sluggish flow in the recirculation region. We hope that the funnel flow analysis around ship's funnel is used for practical optimum funnel design to minimize the exhaust gas dispersion by adjusting the funnel shape, the position of the exhaust pipe, the shape of bulwark, the exhaust direction of air ventilated an engine room and the angle of the exhaust pipe.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1404-1409
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• 2003

The sway control problem of the pendulum motion of the container crane hanging on the trolley, which transports containers from the container ship to the truck, is considered in this paper. In the container crane control problem, the main issue is to suppress the residual swing motion of the container at the end of the acceleration, deceleration or the case of that the unexpected disturbance input exists. For this problem, in general, the trolley motion control strategy is introduced and applied to real plants. In this paper, we suggest a new type of swing motion control system for a crane system in which a small auxiliary mass is installed on the spreader. The actuator reacting against the auxiliary mass applies inertial control forces to the spreader of the container crane to reduce the swing motion in the desired manner. In this paper, we consider that the length of the rope varies is we design the anti-sway control system based on LMI(linear matrix inequality) approach. And, it will be shown that the proposed control strategy is useful and it can be easily applicable to the real world. So, in this study, we investigate usefulness of the proposed anti-sway system and evaluate system performance from simulation and experimental studies.

• Nuclear Engineering and Technology
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• 제52권9호
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• pp.2130-2137
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• 2020

The standard method for calculating anti-neutrino emissions from a reactor involves knowing the fractional fission rates for the most important fissioning nuclides in the reactor. To calculate these rates requires detailed reactor physics calculations based upon the reactor design, fuel design, burnup dependent fuel composition, location of specific fuel assemblies in the core and detailed operational data from the reactor. This has only been published for a few reactors during specific time periods, whereas to be of practical use for anti-neutrino reactor monitoring it is necessary to be able to predict these on the publicly available information from any reactor, especially if using these data to subtract the anti-neutrino signal from other reactors to identify an undeclared reactor and monitor its operation. This paper proposes a method to estimate the fission fractions for a specific reactor based upon publicly available information and provides a database based upon a series of spent fuel inventory calculations using the FISPIN10 code and its associated data libraries.

• 한국군사과학기술학회지
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• 제20권4호
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• pp.579-586
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• 2017

The defense industry has become a global industry, and military technology is actively being traded between countries to increase their military capabilities. The Republic of Korea has been ranked one of the top 10 countries for exports of military technology. To maintain competitive advantages in the global defense industry, it is essential to protect key technologies employed by exported weapon systems. Various techniques have been developed for protection of confidential technologies in weapon systems, and the U.S. DoD has been leading the development of the protection techniques. This paper reviews current anti-tampering techniques that prevent leakage of key technology from weapon exportation or pillage. Based on the protection techniques employed by the U.S. DoD Anti-Tamper Executive Agent, this paper suggests novel design methods for protection of confidential technologies. The proposed design methods were tested on an actual weapon system.

• Asian-Australasian Journal of Animal Sciences
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• 제26권3호
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• pp.386-393
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• 2013

This experiment was conducted to evaluate anti-Salmonella enteritidis (anti-SE) bacteriophage as feed additives to prevent Salmonella enteritidis in broilers. The experimental diets were formulated for 2 phases feeding trial, and 3 different levels (0.05, 0.1 and 0.2%) of anti-SE bacteriophage were supplemented in basal diet. The basal diet was regarded as the control treatment. A total of 320 1-d-old male broilers (Ross 308) were allotted by randomized complete block (RCB) design in 8 replicates with 10 chicks per pen. All birds were raised on rice hull bedding in ambient controlled environment and free access to feed and water. There were no significant differences in body weight gain, feed intake and feed conversion ratio (FCR) at terminal period among treatments (p>0.05). Relative weights of liver, spleen, abdominal fat and tissue muscle of breast obtained from each anti-SE bacteriophage treatment were similar to control, with a slightly higher value in anti-SE bacteriophage 0.2%. In addition, a numerical difference of glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT) and LDL cholesterol level was observed in the 0.2% anti-SE bacteriophage application even though blood profiles were not significantly affected by supplemented levels of anti-SE bacteriophage (p>0.05). In the result of a 14 d record after Salmonella enteritidis challenge of 160 birds from 4 previous treatments, mortality was linearly decreased with increasing anti-SE bacteriophage level (p<0.05), and Salmonella enteritidis concentration in the cecum was decreased with increasing levels of anti-SE bacteriophage (p<0.05). Based on the results of this study, it is considered that supplementation of 0.2% anti-SE bacteriophage may not cause any negative effect on growth, meat production, and it reduces mortality after Salmonella enteritidis challenge. These results imply to a possible use of anti-SE bacteriophage as an alternative feed additive instead of antibiotics in broilers diet.