The GMT-Consortium Large Earth Finder(G-CLEF) is one of the first light instruments at the Giant Magellan Telescope. The international consortium consists of five astronomical institutes including the Center for Astrophysics, the Observatories of Carnegie Institute, the University of Catolica in Chile, the University of Chicago, and Korea Astronomy and Space Science Institute, led by CfA. The extremely precise radial velocity capability is one of the principal instrumental feature of G-CLEF. The RV goal is 10 cm/s capable of detecting an Earth-like planet around a Sun-like host star. This high precision wavelength calibration stability requires a set of significantly tight optomechanical tolerances in the mechanical design of the Flexure Control Camera system. KASI is in charge of the Flexure Control Camera and the Calibration Light System for the G-CLEF spectrograph. In this presentation, we introduce the preliminary design and analysis results of the G-CLEF Flexure Control Camera.
Wesolowsky, Michael J.;Irwin, Peter A.;Galsworthy, Jon K.;Bell, Andrew K.
International Journal of High-Rise Buildings
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v.1
no.1
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pp.15-19
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2012
Occupant footfalls are often the most critical source of floor vibration on upper floors of buildings. Floor motions can degrade the performance of imaging equipment, disrupt sensitive research equipment, and cause discomfort for the occupants. It is essential that low-vibration environments be provided for functionality of sensitive spaces on floors above grade. This requires a sufficiently stiff and massive floor structure that effectively resists the forces exerted from user traffic. Over the past 25 years, generic vibration limits have been developed, which provide frequency dependent sensitivities for wide classes of equipment, and are used extensively in lab design for healthcare and research facilities. The same basis for these curves can be used to quantify acceptable limits of vibration for human comfort, depending on the intended occupancy of the space. When available, manufacturer's vibration criteria for sensitive equipment are expressed in units of acceleration, velocity or displacement and can be specified as zero-to-peak, peak-to-peak, or root-mean-square (rms) with varying frequency ranges and resolutions. Several approaches to prediction of floor vibrations are currently applied in practice. Each method is traceable to fundamental structural dynamics, differing only in the level of complexity assumed for the system response, and the required information for use as model inputs. Three commonly used models are described, as well as key features they possess that make them attractive to use for various applications. A case study is presented of a tall building which has fitness areas on two of the upper floors. The analysis predicted that the motions experienced would be within the given criteria, but showed that if the floor had been more flexible, the potential exists for a locked-in resonance response which could have been felt over large portions of the building.
Kim, Daehyun;Millington, Andrew C.;Lafon, Charles W.
Journal of Ecology and Environment
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v.43
no.4
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pp.364-375
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2019
Background: Ecologists continue to investigate the factors that potentially affect the pattern and magnitude of tree damage during catastrophic windstorms in forests. However, there still is a paucity of research on which trees are more vulnerable to direct damage by winds rather than being knocked down by the fall of another tree. We evaluated this question in a mixed hardwood-softwood forest within the Big Thicket National Preserve (BTNP) of southeast Texas, USA, which was substantially impacted by Hurricane Rita in September 2005. Results: We showed that multiple factors, including tree height, shade-tolerance, height-to-diameter ratio, and neighborhood density (i.e., pre-Rita stem distribution) significantly explained the susceptibility of trees to direct storm damage. We also found that no single factor had pervasive importance over the others and, instead, that all factors were tightly intertwined in a complex way, such that they often complemented each other, and that they contributed simultaneously to the overall susceptibility to and patterns of windstorm damage in the BTNP. Conclusions: Directly damaged trees greatly influence the forest by causing secondary damage to other trees. We propose that directly and indirectly damaged (or susceptible) trees should be considered separately when assessing or predicting the impact of windstorms on a forest ecosystem; to better predict the pathways of community structure reorganization and guide forest management and conservation practices. Forest managers are recommended to adopt a holistic view that considers and combines various components of the forest ecosystem when establishing strategies for mitigating the impact of catastrophic winds.
Wheat gluten is an increasingly common ingredient in poultry diets but its impact on the small intestine in chicken is not fully understood. This study aimed to identify effects of high-gluten diets on chicken small intestines and the variation of their associated transcriptional responses by age. A total of 120 broilers (Ross Strain) were used to perform two animal experiments consisting of two gluten inclusion levels (0% or 25%) by bird's age (1 week or 4 weeks). Transcriptomics and histochemical techniques were employed to study the effect of gluten on their duodenal mucosa using randomly selected 12 broilers (3 chicks per group). A reduction in feed intake and body weight gain was found in the broilers fed a high-gluten containing diet at both ages. Histochemical photomicrographs showed a reduced villus height to crypt depth ratio in the duodenum of gluten-fed broilers at 1 week. We found mainly a significant effect on the gene expression of duodenal mucosa in gluten-fed broilers at 1 week (289 differentially expressed genes [DEGs]). Pathway analyses revealed that the significant DEGs were mainly involved in ribosome, oxidative phosphorylation, and peroxisome proliferator-activated receptor (PPAR) signaling pathways. These pathways are involved in ribosome protein biogenesis, oxidative phosphorylation and fatty acid metabolism, respectively. Our results suggest a pattern of differential gene expression in these pathways that can be linked to chronic inflammation, suppression of cell proliferation, cell cycle arrest and apoptosis. And via such a mode of action, high-gluten inclusion levels in poultry diets could lead to the observed retardation of villi development in the duodenal mucosa of young broiler chicken.
Kim, Changgon;Ji, Tae-geun;Ahn, Hojae;Yang, Mingyeong;Lee, Sumin;Kim, Taeeun;Pak, Soojong;Konidaris, Nicholas P.;Drory, Niv;Froning, Cynthia S.;Hebert, Anthony;Bilgi, Pavan;Blanc, Guillermo A.;Lanz, Alicia E.;Hull, Charles L;Kollmeier, Juna A.;Ramirez, Solange;Wachter, Stefanie;Kreckel, Kathryn;Pellegrini, Eric;Almeida, Andr'es;Case, Scott;Zhelem, Ross;Feger, Tobias;Lawrence, Jon;Lesser, Michael;Herbst, Tom;Sanchez-Gallego, Jose;Bershady, Matthew A;Chattopadhyay, Sabyasachi;Hauser, Andrew;Smith, Michael;Wolf, Marsha J;Yan, Renbin
The Bulletin of The Korean Astronomical Society
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v.46
no.1
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pp.39.1-39.1
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2021
The Local Volume Mapper(LVM) project in the fifth iteration of the Sloan Digital Sky Survey (SDSS-V) will produce large integral-field spectroscopic survey data to understand the physical conditions of the interstellar medium in the Milky Way, the Magellanic Clouds, and other local-volume galaxies. We are developing the LVM Instrument control software. The architecture design of the software follows a hierarchical structure in which the high-level software packages interact with the low-level and mid-level software and hardware components. We adopt the spiral software development model in which the software evolves by iteration of sequential processes, i.e., software requirement analysis, design, code generation, and testing. This spiral model ensures that even after being commissioned, the software can be revised according to new operational requirements. We designed the software by using the Unified Modeling Language, which can visualize functional interactions in structure diagrams. We plan to use the SDSS software framework CLU for the interaction between components, based on the RabbitMQ that implemented the Advanced Message Queuing Protocol (AMQP).
Shivanand Bomman;Sofya Malashanka;Adil Ghafoor;David J. Sanders;Shayan Irani;Richard A. Kozarek;Andrew Ross;Michal Hubka;Rajesh Krishnamoorthi
Clinical Endoscopy
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v.55
no.5
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pp.630-636
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2022
Background/Aims: Transoral incisionless fundoplication (TIF) is an accepted anatomic treatment for gastroesophageal reflux disease in selected patients. In this report, we analyze our institution's programmatic allocation of resources during the safe implementation of TIF as a new procedure. Methods: A retrospective analysis of all patients who underwent TIF from January 2020 to February 2021 at our institution was performed. The process of initially allocating the operating room (OR) with overnight admission and postoperative esophagram for added safety, and subsequently transitioning TIF to the endoscopy suite (ES) as an outpatient procedure was described. Patient safety and outcomes were evaluated during transition. Results: Thirty patients who underwent TIF were identified. The mean age was 51.2±16.0 years. TIF was performed in an OR in nine patients (30%) and 21 (70%) in the ES. All the OR patients were admitted overnight and had routine esophagogram. In contrast, four (19%) from the ES group required clinically-indicated admission and three (14.2%) required esophagram. The mean procedure duration was significantly lower in the ES group (65.7 min vs. 84 min, p=0.02). Conclusions: A stepwise, resource-efficient process was described that allowed safe initiation of TIF as a new technique and its effective transition to a fully outpatient procedure.
The aim of this study was development of the Straight-Wire Appliance(SWA) suitable lot the treatment or Korean. To accomplish the object of this study, Korean adult with normal occlusion were selected with following criteria : 1) no functional abnormality in the craniofacial area, 2) good dental arch form and posterior occlusal relationship, 3) Angle Class I occlusal relationship, 4) no experience of orthodontic, nor prosthodontic treatment, especially, no dental treatment on labial and buccal surfaces of teeth, 5) good racial profile. Impression were taken for upper and lower dental arches or the selected normal occlusion samples and the orthodontic dental stone models were fabricated. 5 well-trained orthodontists had examined the acquired dental stone models to select study samples which satisfy the Six keys to optimal occlusion of Andrews. 155 pairs of dental stone models (92 pairs of Male, 63 of Female) were finally selected. 3 dimensional digitization were performed with the Coordinate Measuring Machine(CMM, MPC802, WEGU-Messtechnik, Germany) and measuring of Angulation, Inclination, In-and-Out, Molar offset angle and Arch form were accomplished with a measuring software to achieve data for the development of SWA. Before the measurement, error study was performed on the 3 dimensional digitization with CMM, and the analysis of reliability of computerized measuring method adapted in this study and conventional manual method Presented by Andrews was performed. Results of this study were as to)lows : 1. Equi-distance digitization with mesh size 0.25 mm, 0.5 mm and 1.0 mm were acceptable in 3 dimensional digitization of dental stone model with the CMM, and the digitization with 1.0 mm mesh size was recommendable in terms of efficiency. 2. Computerized measuring method with 3 dimensional digitization was more reliable than manual measuring method of Andrews. 3. Data were collected for the development of SWA suitable for the morphological characteristics of Korean with the computerized measuring method with 3 dimensional digitization.
Transactions of the Korean Society of Mechanical Engineers B
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v.38
no.9
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pp.757-762
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2014
A solar heat and power hybrid system can simultaneously generate electricity and thermal energy. In this study, several experiments were carried out with a solar heat and power hybrid unit. Then, a method to increase the photovoltaic efficiency and amount of thermal energy was suggested based on a comparative analysis. The experiment was conducted using only the photovoltaic system as a reference case, with the photovoltaic-thermal air system as a hybrid case. A numerical increase in the photovoltaic efficiency per $1^{\circ}C$ was suggested based on a comparative data analysis of these two cases. In this experiment, the surface temperature on the air hybrid system was $13.52^{\circ}C$ lower than that in the reference case, and the photovoltaic efficiency was increased by 5.09. The amount of thermal energy produced was 15.69 Wt per $1^{\circ}C$ difference between the ambient and outlet temperatures. In this paper, therefore, a photovoltaic efficiency increase of 0.34 per $1^{\circ}C$ is proposed for the air hybrid system based on the analysis of the experimental data.
Proceedings of the Korean Society of Crop Science Conference
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2017.06a
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pp.135-135
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2017
The Gramene database (http://www.gramene.org) is a powerful online resource for agricultural researchers, plant breeders and educators that provides easy access to reference data, visualizations and analytical tools for conducting cross-species comparisons. Learn the benefits of using Gramene to enrich your lectures, accelerate your research goals, and respond to your organismal community needs. Gramene's genomes portal hosts browsers for 44 complete reference genomes, including crops and model organisms, each displaying functional annotations, gene-trees with orthologous and paralogous gene classification, and whole-genome alignments. SNP and structural diversity data, available for 11 species, are displayed in the context of gene annotation, protein domains and functional consequences on transcript structure (e.g., missense variant). Browsers from multiple species can be viewed simultaneously with links to community-driven organismal databases. Thus, while hosting the underlying data for comparative studies, the portal also provides unified access to diverse plant community resources, and the ability for communities to upload and display private data sets in multiple standard formats. Our BioMart data mining interface enable complex queries and bulk download of sequence, annotation, homology and variation data. Gramene's pathway portal, the Plant Reactome, hosts over 240 pathways curated in rice and inferred in 66 additional plant species by orthology projection. Users may compare pathways across species, query and visualize curated expression data from EMBL-EBI's Expression Atlas in the context of pathways, analyze genome-scale expression data, and conduct pathway enrichment analysis. Our integrated search database and modern user interface leverage these diverse annotations to facilitate finding genes through selecting auto-suggested filters with interactive views of the results.
Lee, Alex;Seyednejad, Nazgol;Lawati, Yaseen Al;Mattice, Amanda;Anstee, Caitlin;Legacy, Mark;Gilbert, Sebastien;Maziak, Donna E.;Sundaresan, Ramanadhan S.;Villeneuve, Patrick J.;Thompson, Calvin;Seely, Andrew J.E.
Journal of Chest Surgery
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v.55
no.2
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pp.118-125
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2022
Background: A time course analysis was undertaken to evaluate how perioperative process-of-care and outcome measures evolved after implementation of an enhanced recovery after thoracic surgery (ERATS) program. Methods: Outcome and process-of-care measures were compared between patients undergoing major elective thoracic surgery during a 9-month pre-ERATS implementation period to those at 1-3, 4-6, and 7-9 months post-ERATS implementation. Outcome measures included length of stay, the 30-day readmission rate, 30-day emergency department visits, and minor and major adverse events. Process measures included first time to activity, out-of-bed, ambulation, fluid diet, diet as tolerated, as well as removal of the first and last chest tube, epidural, patient-controlled analgesia, and Foley and intravenous catheters. Results: In total, 704 patients (352 pre-ERATS, 352 post-ERATS) were included. Mobilization-related process measures, including time to first activity (16.5 vs. 6.8 hours, p<0.001), out-of-bed (17.6 vs. 8.9 hours, p<0.001), and ambulation (32.4 vs. 25.4 hours, p=0.04) saw statistically significant improvements by 1-3 months post-ERATS implementation compared to pre-ERATS. Time to Foley removal improved by 4-6 months post-ERATS (19.5 vs. 18.2 hours, p=0.003). Outcome measures, including the 30-day readmission rate and emergency department visits, steadily decreased post-ERATS. By 7-9 months post-ERATS, both minor (18.2% vs. 7.9%, p=0.009) and major (13.6% vs. 4.4%, p=0.007) adverse events demonstrated statistically significant improvements. Length of stay trended towards improvement from 6.2 days pre-ERATS to 4.8 days by 7-9 months post-ERATS (p=0.06). Conclusion: The adoption of ERATS led to improvements in multiple process-of-care measures, which may collectively and gradually achieve optimization of clinical outcomes.
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