• Investigative Magnetic Resonance Imaging
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• 제15권2호
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• pp.110-122
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• 2011

목적 : 본 연구의 목적은 확산텐서영상에 기반하여 한국 아동 집단의 해부학적 뇌연결성 지도를 확립하고 뇌신경망의 효율성을 평가하는 기법을 개발하는 것이다. 대상 및 방법 : 건강한 아동 12명에서 얻은 확산텐서영상과 뇌구획영상을 바탕으로 구조 연결 행렬을 구하여 집단의 구조 연결성을 평가하였다. 일표본 t-검정을 시행하여 평균적인 구조 연결성을 파악하였고 이 때 얻은 각 피험자의 백질 다발을 표준공간으로 정규화하여 집단의 해부학적 뇌연결망 지도를 확립했다. 뇌신경망의 군집정도(clustering coefficient), 평균이동거리(characteristic path length), 전체/부분 연결망 효율성(global/local efficiency) 등 연결망 속성을 계산한 후 시각화 하였다. 결과 : 연결망 측면에서 한국 아동 집단의 뇌연결성이 작은세상속성을 가짐을 밝혔다. 또한 해부학적 뇌연결망 지도를 얻었는데 대뇌 반구 내의 연결성이 높게 나타남과 뇌간과 운동/감각 영역간에 많은 신경 연결이 집중되어 있음을 확인하였다. 결론 : 한국 아동 집단의 해부학적 뇌연결망 지도를 작성하는 방법론을 제시하여 뇌를 연결성 측면에서 이해하고 발달 장애와 성인 뇌신경망의 효율성을 평가할 수 있는 기본 도구를 확립하게되었다.

• 대한세포병리학회지
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• 제3권2호
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• pp.82-89
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• 1992

Electron microscopy (EM) can provide a valuable contribution to light microscopy (LM) In the Interpretation of fine needle aspiration cytology (FNAC) specimen, especially in the diagnosis of the tumor. However, considerable care in processing the specimen is mandatory to recover the cells and avoid altering the fine structures. We experienced a case of malignant melanoma in 33-yrs-old female, diagnosed by EM study of FNAC specimen from the axillary mass, who was initially thought as disseminated carcinomatosis on LM study. The technique of EM study on FNAC specimen consisted of washing the needle and syringe in 2.5% glutaraldehyde after a rapid stain (Diff-Quik), which was used to obtain a preliminary diagnostic impression and to assure the adequacy of the EM specimen. After centrifugation in the steps of fixation and dehydration, the sediment was made into an epon block and examined. The whole processing time of EM study can be shortened within 7 or 8 hours, and results can be available within 48 to 72 hours. Our experience suggests the EM study on FNAC can be a useful diagnostic method in the diagnosis of difficult FNAC cases.

• 대한핵의학회지
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• 제37권3호
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• pp.162-170
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• 2003

이 논문에서는 한국인의 뇌 기능 영상 연구에서의 정확한 분석을 위한 한국인 뇌 확률 지도를 제작하였고 이를 실제 기능 영상 연구에 적용할 수 있도록 하는 뇌 위치 정보 추출 프로그램에 대하여 소개하였다. 한국인의 표준 뇌 확률 지도를 작성하기 위하여 정신과적 병력이 없는 정상인 76개의 뇌 영상을 서울대학교 신경정신과와 핵의학과로부터 수집하였으며, 이를 바탕으로 표준 뇌 영상을 결정하였다. 결정된 표준 뇌 영상은 숙련된 전문의로부터 89개의 해부학적 영역으로 분할하는 작업이 이루어졌다. 표준 뇌 영상에서 분할된 정보들은 자동 분할 알고리즘에서의 기준으로 사용되어 나머지 75개의 뇌 영상들에 대해서도 해부학적 정보들을 가지도록 하였다. 76개의 뇌 영상들에 생성된 각각의 89개의 해부학적 정보들은 동일 위치에서의 확률정보로서 변환되어 뇌 확률 지도를 생성하였다. 제작된 한국인의 뇌 확률지도는 한국인의 뇌에 대한 편차 정보와 해부학적인 정보를 가지며 이는 한국인의 기능 영상 연구에 있어서 보다 정확한 결과를 제시할 수 있다.

• 생물정신의학
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• 제2권1호
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• pp.107-114
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• 1995

This study was to investigate the anatomical evidence of anxiety. MRI was used to study 11 patients with panic disorder and 15 patients with complex partial seizure, and 21 controls. The regions of interest in the MRI were measured with computer-assisted planimetry using the AutoCad and digitizer. The following results were obtained ; 1) The mean age was 49.7(12.4) years in patients with panic disorder and 30.1(7.5) years in patients with complex partial seizure. 2) There were na signi ficant differences between 3 groups in the values of cerebral area, temporal lobe, caudate nucleus, hippocampus, parahippocampus, amygdala, third ventricle and VBR. The right parahippocampal region which attracted most attention in neurobiological studies regarding anxiety, tended to be larger in both study groups compared to the control group, but with no statistical significance. 3) There was lett-right reversal of temporal lobes in both study groups. And these are mainly due to asymmetrical increase in area of the temporal lobe on right side. These results suggest that temporal lobe, especially right temporal, is the anatomical correspondence of anxiety and functional activation of temporo-limbic system may be accompanied by the structural change of temporal lobe.

• 대한한의학회지
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• 제35권3호
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• pp.70-92
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• 2014

Objectives: Due to advance of science and IT technology, high tech imaging equipment like ultrasonography, CT, MRI and PET scan is constantly being developed and progressed; use of these techniques is needed for Korean medicine. Methods: Historical study was undertaken on the evidence of using ultrasonography. Normal organs and various sorts of diseases were also observed by ultrasonography. Results: Korean medicine judges disease of internal organs and condition of health by symptoms of functional disease and organic disease based on anatomical theory. Ultrasonography based on anatomical theory is non-invasive and free from radiation exposure and can be performed directly from clinical practice in real-time. Ultrasonography can be a big help for securing the stability of the internal organs in inserting needles in the thorax and abdomen as well as diagnosing functional and organic diseases based on anatomical theory. Conclusion: We look forward to a great development of scientification and objectification of Korean medicine by using and researching imaging equipment based on anatomical theory as well as ultrasonography.

• Anatomy and Cell Biology
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• 제56권4호
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• pp.409-414
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• 2023

Botulinum neurotoxin (BoNT) injection for the treating plunged nose, post-rhinopasty and hyaluronic filler migration is common procedures in clinical settings. However, the lack of thorough anatomical understanding makes it difficult to locate the nose region muscles. The anatomical considerations concerned with BoNT injection into the nasalis, levator labii superioris alaeque, and depressor septi nasi muscles were reviewed in this study. The injection spots have been presented for the nasalis, levator labii superioris alaeque, and depressor septi nasi muscles, with the recommended injection technique for each muscle. We have suggested the ideal injection sites in association with outer anatomical landmarks of the nose region. Moreover, these proposals would support a more accurate procedure of BoNT injection in relieving plunged nose, preventing post-rhinoplasty deviation, and migration of the hyaluronic acid filler.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.279-282
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• 2012

Background: Although more than two third of colorectal cancers are localized on the left side, recent studies suggest a right ward shift in anatomical distribution with increase in proximal colon cancers. The aim of the present study was to determine the anatomical distribution of colorectal cancer in a referral center over a 15 year period. Method: Records of patients who underwent colectomy in the Cancer Institute of Iran from 1994 to 2009 were retrieved. Data including anatomical localization, year of diagnosis, patient age and gender, tumor histology and differentiation, and disease stage were extracted. Tumors located from the cecum to the distal transverse colon were classified as right side and those occurring from the splenic flexure to the descending colon as left-sided. Cancer of rectum and recto-sigmoid junction were considered as rectal cancers. Results: A total of 442 patients including 220 (49/8%) men and 222 (50/2%) women with mean age 53 were included. Most patients were in stage II &III (47.1% and 33% respectively). There were 157 (35.5 %) colon cancers and 285 (64.5%) rectal cancers. 43.3% of the colon cancers were right sided and 56.7% were left sided. There was no statistically significant increase in right sided cancer during the period of the study. There were no significant differences in age at diagnosis, gender, grade and stage of tumor between the right and the left sided cancers. Conclusion: No proximal shift over time was identified in our study.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.951-955
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• 2014

Background: Colorectal cancer (CRC) was the fourth most commonly diagnosed cancer in Iran between 2000 and 2009, with adenocarcinoma (AC) as the most common histological type. Demographic, topographic and histological variables are important in the epidemiology and biology of cancer. The aim of this study was to investigate clinicopathological features of colon adenocarcinomas in Qazvin, Iran. Materials and Methods: With a retrospective design, patient records of two pathology wards from March 1997 to March 2013 were studied with regard to anatomical location and histological classification. A broader anatomical grouping was also used including distal vs proximal regions and right sided vs left sided tumors. Data were analyzed using T-test and chi-square test. Results: 118 (50.9%) male and 114 (49.1%) female patients were included in the study. Mean age was $57.3{\pm}14.7$ years, with 29.2% under 50 years. There was no significant gender difference for age at diagnosis. The rectum (56%) and sigmoid colon (25%) were the most frequent anatomical locations. Proximal cases accounted for 18.6% in males and 8.8% in females (p=0.02). AC was more prevalent than other usual types in younger patients. The proportion of proximal cancer was 1.7% in first eight years of the study period vs 12.1% in the second one (p=0.005). A similar trend was also seen in right sided colon cancers (p=0.018). Conclusions: Young people are also at risk for the cancer with poor prognosis. Screening programs and weight loss in obese individuals can reduce incidence and complications of CRC.

• Archives of Plastic Surgery
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• 제47권2호
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• pp.165-170
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• 2020

Background Perforator mapping has been well described in the literature. Once the suprafascial plane is reached, the course of perforators is considered constant. However, the surgeon must be aware of whether an anastomosis exists between perforators superficially to the fascia, in order to choose the best vessel upon which to base the reconstruction. Our retrospective in vivo anatomical study of lower leg perforator flaps presents the first description of variations in the suprafascial path of perforators, which may influence preoperative flap design. Methods An anatomical study of lower limb perforators was performed on 46 nonconsecutive patients who were referred to our department from June 2012 to October 2018. Reconstruction with perforator-based propeller flaps was planned for each of the patients. In total, 72 perforators were preoperatively identified and surgically isolated. The suprafascial course of each perforator was reported. Results During suprafascial surgical exploration, branching patterns were observed in four perforators. These perforators had been classified as single vessels in the preoperative ultrasonographic analysis. However, after surgical dissection, distal converging branches were noted in two of them. Conclusions Our study is the first description in the literature of suprafascial converging perforators, which might constitute an obstacle to planned reconstruction procedures. Despite the accuracy of preoperative evaluations, anatomical variations were present. Knowledge of suprafascial perforator variations may help surgeons to choose the correct perforator upon which to base a planned flap.

• 한국산림과학회지
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• 제2권1호
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• pp.37-40
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• 1962

1) The greater parts of rail road cross tie wood in Korea have been supplied by the imported woods from foreign countries such as Formosa (Taiwan) and Japan. However on account of anatomical properties on these imported woods are not known when newly imported, identification and preservative treatment are apt to fail. Accordingly this expriment was accomplished by the need of application of anatomical properties for the preservative treatment and identification of several imported woods. 2) In this study macroscopical and microscopical properties were inspected and briefly described about four species (Cyclobalanopsis gilva Blume, Castanopsis longicaudata K. et H., Machilus longiflora Hay and Schima superba Gard et Champ) from Formosa and one (Fagus crenata, Blume) from Japan. With several native species these are important as the rail road tie wood in Korea. 3) According to the results measured values of the vessels and fibers of each tested species are as following table.