• Journal of the Korean Society for Precision Engineering
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• v.28 no.7
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• pp.789-795
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• 2011

In elliptical vibration cutting (EVC), cutting performance is largely affected by the shape of an elliptical path of the cutting tool. In this study, two parallel piezoelectric actuators were used to make an elliptical vibration cutting device. When harmonic voltages of $90^{\circ}$ out-of-phase are supplied to the EVC device, creation of an ideal elliptical trajectory whose major and minor axes are parallel to the cutting and thrust directions is anticipated from a kinematic analysis of the EVC device, however, the paths we experimentally observed showed significant distortions in its shape ranging from skew to excessive elongation of the major axis of the ellipse. To compensate distortions, an analytical model describing the elliptical path of the cutting tool was developed and verified with experimental results, and based on the analytical model, the distorted elliptical paths created at 100 Hz, 1 kHz, and 16 kHz were corrected for skew and elongation.

• Journal of Environmental Health Sciences
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• v.37 no.1
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• pp.57-63
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• 2011

Crocidolite quality control (QC) sampling created by the wet generation method has been validated by validation tests such as the accuracy, precision, and storage tests. For this study we designed and developed a manufacturing apparatus and standard operating procedure for making these QC samples. The most important step in the procedure of making QC samples was the stage eliminating static electricity in asbestos fibers. This static electricity hampers the fibers clog functioning. In accuracy and precision tests by phase contrast microscopy analysis, the difference between the reference values and the studied values was at maximum 17.8%. This satisfies the AIHA proficiency analytical test criteria for asbestos. We could confirm the nearly even distribution of crocidolite fibers on the membrane filter. Also, there was no loss of fibers in the storage test after the one month.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.4 no.1
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• pp.103-116
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• 1994

This study was conducted to evaluate accuracy and precision of reference values used for quality control of the Korean industrial hygiene laboratory for three rounds. Factors affecting on accuracy and precision, including analytical procedures, were investigated. The results are summarized as follows. 1. Pooled relative standard deviation of reference values analyzed by reference laboratories was 2.01-5.91%, and that by both reference laboratories and participated laboratories was 3.18-6.63%. Better results were obtained when results of reference laboratories were employed. 2. Significant relationship was indicated between analytical precision and concentration of materials in samples. Variation increased by decreasing sample concentration. 3. Recoveries of lead and cadmium were about 98.6% and 99.8% respectively. There was a significant difference between lead values with and without recovery correction. 4. Organic solvent results corrected by desorption efficiency only and those corrected by Both internal standards and desorption efficiency were more accurate than those uncorrected. But, the latter was the best.

• Analytical Science and Technology
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• v.30 no.5
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• pp.221-225
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• 2017

Thioctic acid is a vitamin-like antioxidant which is prepared as tablets and injection. The Korean Pharmacopoeia (KP XI) contains monograph for the quality control of raw thioctic acid using ultra-violet visible spectrophotometry and its formulations using high performance liquid chromatography (HPLC). In British Pharmacopoeia 2013 (BP2013), another HPLC method is used for the assay test of thioctic acid material. For the international harmonization, we present an HPLC method for quantitation of thioctic acid in both raw material and tablets. Method validation was performed to determine linearity, precision, accuracy, system suitability, and robustness. The linearity of calibration curves in the desired concentration range was high ($r^2=0.9995$), while the RSDs for intra- and inter-day precision were 0.93 ~ 1.26 % and 1.40 ~ 1.76 %, respectively. Accuracies ranged from 98.13-100.00 %. Since the system suitability, intermediate-precision and robustness of the assay were satisfactory, this method will be a valuable addition to the Korean Pharmacopoeia (KP XI).

• Journal of Korean Society for Atmospheric Environment
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• v.16 no.3
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• pp.265-275
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• 2000

By using thermal desorption/gas chromatograph/flame ionization detector(TD/GC/FID), this study was carried out to evalute an accuracy and a precision on Benzene(B), Toluene(T), o-Xylene(X) analysis in an industrial hygiene laboratory. Limits of detection of TD/GC/FID on B, T, X were showed 13.75ng/sample or less. For the accuracy of the method by concentration levels, overall bias was showed 7.7% as an absolute value, and the pooled coefficient of variation showed 3.51%. For the precision on repeatability of peak area and retention time between within-run and between-run of analytical system, it is showed the results of within-run gave better than those of between-run. Also the accuracy by sorbents(Tenax TA and Chromosorb 106)was evaluated, and the precision on reproducibility between MDHS72 and this study was compared. It is showed it is possible for TD/GC/FID to evaluate accurately B, T, X concentration levels of less than 1ppm at indoor or outdoor of workplaces in Korea.

• Journal of Korean Society for Atmospheric Environment
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• v.13 no.5
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• pp.355-360
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• 1997

The atmospheric concentration of dimethylsulfide (DMS), known as the predominant volatile organic. sulfur compound, is determined at subnanogram level by a combined application of non-cryogenic preconcentration method and gas chromatography with flame photometric detection (GC/FPD). The volatile DMS in air is preconcentrated using a trapping tube containing adsorbent like Molecular Sieve 5A (or gold-coated sands). The tube is then connected to the GC/FPD system via a six-way rotary valve, thermally desorbed at 40$0^{\circ}C$, separated on OV101 column, and detected by a flame photometric detector. The DMS peak elutes at about 2.5 mins and is integrated electronically. The analytical precision, if expressed in terms of relative standard error, is around 5%. The detection limit of our GC/FPD system is ca 1 ng of DMS. Details of our analytical system are presented.

• Bulletin of the Korean Chemical Society
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• v.14 no.6
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• pp.696-700
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• 1993

Gold bonding wire of 0.076 mm in diameter used in semiconductor industry, is dissoved in aqua regia. The solution is then evaporated to near dryness several times with a few drops of HCl added to prepare the final sample solution in 5% HCl. The gold matrix is separated from trace impurities by controlled potential deposition. The whole electrolysis has been carried out inside a clean bench. An optimum potential is found to be +0.25 V to give more than 99.9% Au matrix removal with better than 90 analytes remaining in the electrolyte solution. Isotope dilution calibration is employed to get the best accuracy and precision. Analytical results are presented with determination limits of the analytical method.

• Analytical Science and Technology
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• v.6 no.3
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• pp.345-348
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• 1993

A monchromator controller has been built to drive directly by a personal computer. This controller gives better conveniency and accuracy on spectroscopic experiment when a monochromator has deficient driver. This controller consists with simple electronic circuit and control program. The original spectroscopic precision is retained by using stepper motor. The rate changing method is adopted for short slew time. And the scanning is synchronized with spectrum recording device. Because the controller includes electronic counting ciruit, other program can be executed on personal computer during monochromator scanning.

• Analytical Science and Technology
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• v.32 no.4
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• pp.147-154
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• 2019

Ampicillin and Sulbactam (2:1, w/w) are combined in formulation to provide broader antibacterial action in treatment of many infections. The development of analytical method for simultaneouly determine these two compounds was difficult because of the differences in their chemical structures and ratio in the formulation. Current published methods still have some limitations. In this study, we developed an alternative high-performance liquid chromatography (HPLC) assay method for simultaneously determination of ampicillin sodium and sulbactam sodium in powder for injection. Method validation of HPLC method was conducted to determine linearity, precision, accuracy, system suitability, robustness. The linearity of the calibration curves in the desired concentration range was good ($r^2$> 0.9994). RSDs of intra-day and inter-day precision obtained were less than 2.00 %. Accuracy was obtained with the recoveries in range of 98.42 % and 101.36 %. As a result of system suitability, RSD of both retention time and the peak area obtained were not more than 1.0 %. The values of plate number were more than 7000 and symmetric factors obtained were 0.8. As intermediate-precision and robustness of the developed assay, it could be expected to become valuable tools for revising the Korean Pharmacopoeia (KP XI).

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.61-62
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• 2013