• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6977-6984
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• 2015

It is faced with the necessity of multi roll forming process of the ball slide rail which is made by adding the separate manufacturing processes, piercing, bending, trimming, to the roll forming process of a continuous plastic deformation, to improve the quality. However, the vibration and noise of the press machine in this process leads to the quality degradation of slide rail manufactured in this process. In this study, the roll was designed considering the optimal strain rates by the roll forming program with finite element method. And to estimate the static stability of the multi process the Von-Mises stress and deformation on the press was calculated with a structural analysis program. Also, to avoid driving systems in the resonance region their natural frequencies in the 1st and 2nd mode were calculated through the modal analysis. To verify its dynamic stability improvement the magnitudes of noise and vibration in the existing and studied system were compared using a microphone and accelerometers. And the widths and surface roughnesses of the rails which had been produced in the existing and studied process were measured. Therefore, it is known that multi roll forming process is stable in the analytical and experimental study.

• Analytical Science and Technology
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• v.25 no.1
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• pp.19-24
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• 2012

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the quantitative determination of ertapenem in human plasma and urine. After addition of internal standard (ceftazidime), plasma and urine was diluted with methanol and analyzed by LC-MS/MS. Using MS/MS with multiple reaction monitoring (MRM) mode, ertapenem were selectively detected without severeinterference from human plasma and urine. The standard calibration curve for ertapenem was linear ($r^2$= 0.9996)over the concentration range 1~100 ${\mu}g/mL$ in human plasma. The intra- and inter-day precision over the concentration range of ertapenem was lower than 8.9% (correlation of variance, CV), and accuracy was between 97.2~106.2%. On the other hand, it was showed good relationship ($r^2$= 0.9992) and the precision (intra- and inter-day) over the concentration range of ertapenem was lower than CV 7.2%, and accuracy was between 97.9~111.6% for urine. This method has been successfully applied to the pharmacokinetic study of ertapenem in human plasma and urine.

• Journal of Korean Society of Transportation
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• v.26 no.6
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• pp.113-122
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• 2008

This study extended Park et al.(2007c), which analyzed the efficiency of a hierarchical transit network, showed the result of a real data, and analyzed its applicability. Operating cost was estimated using a model which was established in this study, and minimum transit demand was derived from the operating cost. The minimum transit demand value is just a sample calculation, thus it varies by many inside and outside factors of the model. Looking at the inside of the model, operating cost and travel speed are major factors, and the possibility of introducing urban subway becomes high when the operating cost of the transit system is low and its travel speed is high. As far as the outside factors are concerned, according to the analysis on the network structure, transit demand, and transit mode share, the minimum transit demand value which was derived in this study will be the maximum value among the possible values. In the feasibility study, the benefit is likely to be overestimated and the cost is likely to be underestimated than those of this study. It could be concluded that the methodology of a feasibility study is appropriate in the field standard. This study analyzed the efficiency of introduction of urban subway using analytical approach, thus has many shortcomings and limitations. However the practical approach, like feasibility study, has some limitations as well. This study could be a basis on establishing an analysis framework that is more accurate and reasonable by comparing analytical approach and practical approach.

• Analytical Science and Technology
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• v.26 no.5
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• pp.315-325
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• 2013

The possibility of acute hepatotoxicity caused by dimethylformamide (DMF) requires regular monitoring of the workers who are using DMF to prevent the occupational disease. The authors performed ambient and biological monitoring of workers involved in synthetic leather manufacturing processes using DMF to assess the correlation between the markers of ambient and biological monitoring of DMF. The authors monitored 142 workers occupationally exposed to DMF from 19 workshops in the synthetic leather and ink manufacturing industries located in northern region of Gyeonggi-do. The subjects answered questionnaire on work procedure and use of personal protective equipment to be classified by exposure type. DMF in air samples collected using personal air samplers, diffusive and active sampler, was analysed using gas chromatograph-flame ionization detector (GC-FID) with DB-FFAP column (length 30 m, i.d. 0.25 mm, film thickness 0.25 ${\mu}m$). Urinary N-methylformamide (NMF) was analysed using gas chromatograph-mass selective detector (GC-MSD) at selected ion monitoring (SIM) mode with DB-624 column (length 60 m, i.d. 0.25 mm, film thickness 1.40 ${\mu}m$). Geometric mean (GM) and geometric standard deviation (GSD) of the ambient DMF was $6.85{\pm}3.43$ ppm, and GM and GSD of urinary NMF was $42.3{\pm}2.7$ mg/L. The ratio of subjects with DMF level over 10 ppm was 44%, and those with urinary NMF over 15 mg/L was 87%. NMF in urine adjusted by DMF in air was $4.61{\pm}2.57$ mg/L/ppm and $9.50{\pm}2.41$ mg/L/ppm, respectively, with or without respirator. There was seasonal differences of NMF in urine adjusted by DMF in air, $7.63{\pm}2.74$ mg/L/ppm in summer and $4.53{\pm}2.29$ mg/L/ppm in winter. The urinary NMF concentration which corresponds to 10 ppm of ambient DMF was 52.7 mg/L (r=0.650, n=128). Considering the difference of the route of exposure which resulted from the compliance of wearing personal protective equipment, the estimated contribution of respiratory and dermal exposure route for DMF was 48.5% vs. 51.5%.

• Journal of the Earthquake Engineering Society of Korea
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• v.13 no.1
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• pp.35-43
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• 2009

Two types of piloti-type high-rise RC building structures having irregularity in the lower two stories were selected as prototypes, and nonlinear time history analysis was performed using OpenSees to verify the analysis technique and to investigate the seismic capacity of those buildings. One of the buildings studied had a symmetrical moment-resisting frame (BF), while the other had an infilled shear wall in only one of the exterior frames (ESW). A fiber model, consisting of concrete and reinforcing bar represented from the stress-strain relationship, was adapted and used to simulate the nonlinearity of members, and MVLEM (Multi Vertical Linear Element Model) was used to simulate the behavior of the wall. The analytical results simulate the behavior of piloti-type high-rise RC building structures well, including the stiffness and yield force of piloti stories, the rocking behavior of the upper structure and the variation of the axial stiffness of the column due to variation in loading condition. However, MVLEM has a limitation in simulating the abrupt increasing lateral stiffness of a wall, due to the torsional mode behavior of the building. The design force obtained from a nonlinear time history analysis was shown to be about $20{\sim}30%$ smaller than that obtained in the experiment. For this reason, further research is required to match the analytical results with real structures, in order to use nonlinear time history analysis in designing a piloti-type high-rise RC building.

• Structural Engineering and Mechanics
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• v.31 no.2
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• pp.181-210
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• 2009

This paper presents the theoretical developments of an exact finite strip for the buckling and initial post-buckling analyses of isotropic flat plates. The so-called exact finite strip is assumed to be simply supported out-of-plane at the loaded ends. The strip is developed based on the concept that it is effectively a plate. The present method, which is designated by the name Full-analytical Finite Strip Method in this paper, provides an efficient and extremely accurate buckling solution. In the development process, the Von-Karman's equilibrium equation is solved exactly to obtain the buckling loads and the corresponding form of out-of-plane buckling deflection modes. The investigation of thin flat plate buckling behavior is then extended to an initial post-buckling study with the assumption that the deflected form immediately after the buckling is the same as that obtained for the buckling. It is noted that in the present method, only one of the calculated out-of-plane buckling deflection modes, corresponding to the lowest buckling load, i.e., the first mode is used for the initial post-buckling study. Thus, the postbuckling study is effectively a single-term analysis, which is attempted by utilizing the so-called semi-energy method. In this method, the Von-Karman's compatibility equation governing the behavior of isotropic flat plates is used together with a consideration of the total strain energy of the plate. Through the solution of the compatibility equation, the in-plane displacement functions which are themselves related to the Airy stress function are developed in terms of the unknown coefficient in the assumed out-of-plane deflection function. These in-plane and out-of-plane deflected functions are then substituted in the total strain energy expressions and the theorem of minimum total potential energy is applied to solve for the unknown coefficient. The developed method is subsequently applied to analyze the initial postbuckling behavior of some representative thin flat plates for which the results are also obtained through the application of a semi-analytical finite strip method. Through the comparison of the results and the appropriate discussion, the knowledge of the level of capability of the developed method is significantly promoted.

• YAKHAK HOEJI
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• v.52 no.6
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• pp.419-425
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• 2008

A qualitative and quantitative analytical method was developed for detection of methamphetamine (MA) and its main metabolite amphetamine (AM) in oral fluid. Oral fluids of eleven drug abusers were provided by Police, specimens were collected by stimulation with a cotton swab treated with 20 mg of citric acid ($Salivette^{(R)}$; Sarstedt, USA). As the preliminary test, oral fluid samples were screened for amphetamines by Fluorescence Polarization Immunoassay (TDxFLx, Abbott Co.). Extraction for MA was performed using solid-phase extraction (SPE) by $RapidTrace^{TM}$ (Zymark, USA) with mixed mode cation exchange cartridge, CLEAN $SCREEN^{(R)}$ (130 mg/3 ml, UCT) after dilution with phosphate buffer. Samples were evaporated and derivatized by pentafluoropropionic acid anhydride (PFPA). Quantitation of MA and AM was performed by gas chromatography-mass spectrometry (GC-MS) using selective ion monitoring (SIM), the quantitation ions were m/z 204 (MA), 208 (MA-$D_5$), 190 (AM) and 194 (AM-$D_5$). The selectivity, linearity of calibration, limit of detection (LOD) and quantification (LOQ) within- and between day precision, accuracy and recoveries were examined as parts of the method validation. All oral fluid samples gave positive results to immunoassay for MA (cut-off level, 50 ng/ml as d-amphetamine). Concentrations of MA and AM by GC-MS in eleven samples were ranged 104.2${\sim}$4603.3 ng/ml and 32.4${\sim}$268.6 ng/ml, respectively. Extracted calibration curves of MA and AM were linear over the two concentration range of 1${\sim}$100 and 50${\sim}$1000 ng/ml with correlation coefficient of above 0.999. LOQ of MA and AM was 1 and 3 ng/ml, respectively. The intraand inter-day run precisions (CV) for MA and AM were less than 10%, and the accuracies (bias) for MA and AM were also less than 10% at the two different concentrations 5 and 100 ng/ml at low calibration range, 50 and 1000 ng/ml at high calibration range. The absolute recoveries of MA and AM at low and high calibration ranges were more than 82% and 75%, respectively. In this study the qualitative and quantitative analytical method of MA in oral fluid was established. Oral fluid testing may detect drug use in past hours because of its shorter detection window than urine, and be useful in post-accident situations. So oral fluids will be most useful for testing drug abuse in the driving under the influence of drug (DUID) as the alternative specimens of urine.

• Journal of the Earthquake Engineering Society of Korea
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• v.12 no.5
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• pp.47-56
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• 2008

This study was performed to evaluate the effect of Response modification factors (R-factor) in 3-, 9- and 20- story steel Moment Resisting Frame (MRF) buildings. Each structure was designed using a R-factor of 8, as tabulated in the 2000 International Building Code provision (IBC 2000) and Korea Building Code (KBC) 2008. In order to evaluate the maximum and minimum performance expected for such structures, an upper bound and lower bound design were adopted for each model. Next, each analytical model was designed using different R-factors (8, 9, 10, 11, 12) and four different structural periods with the original fundamental period. For a detailed case study, a total of 150 analytical models were subjected to 20 ground motions representing a hazard level with a 2% probability of being exceeded in 50 years. In order to evaluate the performance of the structures, static push-over and non-linear time history analysis (NTHA) were performed, and displacement ductility demand was investigated to consider the ductility capacity of the structures. The results show that the dynamic behaviors for the 3- and 9-story buildings are relatively stable and conservative, while the 20-story buildings show a large displacement ductility demand due to dynamic instability factors. (e.g. P-delta effect and high mode effect)

• Analytical Science and Technology
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• v.13 no.4
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• pp.504-510
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• 2000

The impurity profiles from the raw materials of glycyrrhizin were performed by the high performance liquid chromatography (HPLC)/electrospray ionization (ESI)- mass spectrometry (MS). For the HPLC experiment, a $C_{18}$($3.9{\times}300mm$, $10{\mu}m$) column was used and the mobile phase was acetic acid/$H_2O$ (1:10):acetonitrile=3:2 with a flow rate of 0.8 ml/min. The effluent was splitted into the ratio of 50:1 and went into the ESI-MS. Three to six impurities were found and informed of the identification of the structure of the impurities by ESI-MS. And the structures of impurities were suggested to a hydroxy-glycyrrhizin which is added with hydroxy group (-OH) in the glycyrrhetic acid moiety and a reduced-glycyrrhizin which the position of 12 of the glycyrrhetic acid moiety is reduced. The purities of the standard materials were about 90%.

• 한국해양학회지
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• v.29 no.2
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• pp.119-131
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• 1994

Vertical structures of wind-driven and tidal currents in a rectangular shaped uniform-depth basin of homogeneous water have been investigated using a mode-splitted, multi-level grid-box, hydrodynamic numerical model. The model was verified using analytical solutions for various vertical eddy viscosity profiles such as: a constant eddy viscosity, a linearly decreasing or increasing variation with depth, a quadratic variation with depth and an exponential variation with depth. Particular attention has been paid on the effects of "near-surface wall layer" on vertical shear of velocity. In numerical calculations, the whole water depth was divided into 13 levels with an unequal grid spacing. the model satisfactorily reproduces the velocity profile, but in case the eddy viscosity decreases rapidly with depth as in quadratical or exponential variation with depth, the vertical gradient of velocity near the bottom became very steep, and analytical solutions and numerical results showed some discrepancy. The vertical structures of horizontal velocity vary with both the depth-averaged value of eddy viscosity and its profiles. the velocity near the sea surface and near the bottom responded sensitively to the eddy viscosity of wall layer. For wind-driven current, the strong velocity shear was generated near the sea surface as eddy viscosity near the surface became small. For tidal current, the velocity above the sea bottom layer was almost constant regardless of the profiles of vertical eddy viscosity, but velocity in the sea bottom layer showed strong shear as eddy viscosity became small.