• Title/Summary/Keyword: Analogs

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Synthetic $\beta$-Lactam Antibiotics V. Antibacterial Activity of Some 7$\beta$[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-(quinolinium)thiomethylcephalosporins

  • Lim, Dong-Yeol;Park, Sang-Woo;Kim, You-Seung
    • Archives of Pharmacal Research
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    • v.14 no.3
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    • pp.279-281
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    • 1991
  • In the field of cephalosporins, introduction of quaternary heterocyclic methyl goups at the C-3 position has led to a new class of cephalosporins such as cefepime and cefpirome, the so-called 4th generation cephalosporins which are characterized by their potent activity. Since than many efforts were attempted to synthesize more effective analogs.

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Reactivity and Suitability of t-Boc-protected Thiophosphotyrosine Intermediate Analogs for the Solid or Solution Phase Peptide Synthesis

  • Kim, Eun-Kyung;Choi, Hee-Sung;Lee, Eung-Seok
    • Archives of Pharmacal Research
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    • v.21 no.3
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    • pp.330-337
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    • 1998
  • N-(tert-Butoxycarbonyl)-O-(dimethythiophosphono)-L-tyrosine (6) and N-(tert-butoxycarbonyl)-O-(dicyanoethylthiophosphono)-L-tyrosine (15) were prepared as intermediates for the synthesis of thiophosphotyrosine-containing peptides. The reactivity and suitability of two compounds for the solid phase or solution phase peptide synthesis utilizing t-Boc chemistry were examined.

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SECOND CHERN NUMBERS OF VECTOR BUNDLES AND HIGHER ADELES

  • Osipov, Denis V.
    • Bulletin of the Korean Mathematical Society
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    • v.54 no.5
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    • pp.1699-1718
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    • 2017
  • We give a construction of the second Chern number of a vector bundle over a smooth projective surface by means of adelic transition matrices for the vector bundle. The construction does not use an algebraic K-theory and depends on the canonical ${\mathbb{Z}}-torsor$ of a locally linearly compact k-vector space. Analogs of certain auxiliary results for the case of an arithmetic surface are also discussed.

Benzastatin J, a New Demethylated Derivative of Benzastatin B Produced by Controlled Fermentation of Streptomyces nitrosporeus

  • Kim, Won-Gon;Yoo, Ick-Dong
    • Journal of Microbiology and Biotechnology
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    • v.12 no.5
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    • pp.838-840
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    • 2002
  • Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Strepromyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.

Effects of slow release gonadotropin releasing hormone analog on milt characteristics and plasma levels of gonadal steroids in greenback flounder, Rhombosolea tapirina

  • Lim, Han-Kyu
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2003.05a
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    • pp.187-188
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    • 2003
  • Conadotropin releasing hormono analogs (GnRHa) have now been tested successfully a range of marine and freshwater species and been shown to be an effective strategy for improving milt quantity and quality (Mylonas and Zohar, 2001; Zohar and Mylonas, 2001; Lim et at, , 2002). Greenback flounder (Rhombosolea tapirina) is currently under consideration as a potential culture species in south-eastern Australia. (omitted)

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Aziridine analogs of HIV NNRTI trovidine

  • Jung, Sang-Hun;Kim, Il-Whan;Kim, Jin-Myoung;Han, Sang-Sub;Joe, Soo-Hyun;Lee, Jee-Hyun;Lee, Chong-Kyo;Park, Kyung-Lae
    • Proceedings of the PSK Conference
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    • 2001.10a
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    • pp.240.3-241
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    • 2001
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