• Title/Summary/Keyword: An Aging Society

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Chestnut Extracts as new Anti-aging agent

  • 김범준;김정하
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.1
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    • pp.113-126
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    • 1998
  • Inner nutshell of Castanea crenata has been used as an anti-aging and anti-wrinkle agent from the ancient time in east Asia. In order to develop new anti-aging and anti-wrinkle, ethanolic extract of inner nutshell of Castanea crenata was prepared and various biological activities were evaluated. Cor-285 possessed potent tree radical scavenging activity in vitro compared to gallic acid. Cor-285 showed the preventive effect against UV-induced cytotoxicity of fibroblast at concentration of 25-250mg/ml. When Cor-285 was evaluated for its anti-allergic activity, it effectively inhibited histamine release from mast cells induced by compound 48/80. The inhibitory activity was stronger than that of glycyrrhizinate. Cor-285 also showed on vivo inhibition against delayed hypersensitivity as well as croton-oil induced ear edema in mice when topically applied. These results strongly suggest that Cor-285 may reduce immunoregulatory/inflammatory skin trouble. From the attempts to isolate the scavenger, were isolated. In a clinical trial of twenty healthy volunteers with aged skin, 6 weeks application of Cor-285 decreased wrinkle about 26% and increased moisturizing 20% on the skin. All of these results indicate that Cor-285 may be an effective anti-aging and anti-wrinkle agent.

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Target Proteins Involved in Aging Mechanism as an Aging Molecular Marker (노화 분자마커로서 노화기전에 관여하는 타켓 단백질)

  • Kim, Moon-Moo
    • Journal of Life Science
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    • v.26 no.8
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    • pp.983-989
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    • 2016
  • All cells composing of our body undergo their destiny such as proliferation, differentiation, necrosis, apoptosis and senescence depending on their circumstance with time. The errors occurring in these processes develop several aberrations in phenotypes including cancer, inflammation, aging and diseases. New strategy and approach are required to screen anti-aging compounds derived from natural products. Therefore, here we explain the target proteins to play a key role in aging mechanism. In the first place, matrix metalloproteinases (MMPs) are involved in metastasis, chronic inflammation and skin aging as an aging marker. In particular, histone deacetylases (HDACs) give a great attention to aging researchers who try to extend the life span of animal model. In addition, we describe the signaling pathway related to senescence which p53, IGF-1 and SIRT1 play an important role in. Furthermore, autophagy is involved in the signaling pathway associated with aging. Several new compounds modulating the signaling pathway of senescence are introduced in this review. Here, we try to provide a new insight in the molecular basis for the aging mechanism and development of aging marker. In addition, the compounds introduced here could be available for pharmaceutical applications for the prevention and the treatment of diseases related to aging.

THE INFLUENCE OF SOY ISOFLAVON TO THE SKIN AGING IN PRE- MENOPAUSAL WOMEN

  • Subchan, P.;Tranggono, R.I.S.;Djajadisastra, J.
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.73-84
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    • 2003
  • Skin aging process on pre-menopausal women is a problem that needs to be prevented as early as possible. The decrease of oestrogen level which is one of the intrinsic factors of the skin aging process will affect the skin biological process, due to oestrogen receptors on the skin. A number of researches conducted on pre-menopausal women with the allocation of oestrogen hormone resulted in delaying the skin aging process. The administration of soy isoflavon, a phytoestrogen found in daily food, on pre-menopausal women is hoped to be able to prevent skin aging process, even clinically or molecular biologically. This research aims to explain the benefit of administering of soy isoflavon on skin aging process. The design of the research is randomised controlled trial (RCT). As many as 60 pre-menopausal women were collected with simple random sampling method. Soy isoflavon is an independent variable, while skin aging process is a dependent variable assessed from the hydration, sebum level, average roughness, depth of wrinkles, skin clarity, length of the telomere. Analysis was conducted using t and MANDVA tests and.the result showed a significance (F = 10,439; p = 0,001) over the allocation of soy isoflavon to the whole variable dependent, including the telomere length and the skin hydration, meant that allocation of soy isoflavon could delay skin aging process.

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Characteristics of Housing Preference for Each Aging Situation before and after Providing Information of Aging Society (고령화사회 관련 정보제공 전·후의 노후상황별 주거선호 특성)

  • Lee, Yeunsook;Shin, Hwa-Kyoung;Lee, Dong-Joo;Yoon, Hae-Kyung;Lee, Joon-Min;Yoo, Hea-Jung
    • KIEAE Journal
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    • v.11 no.5
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    • pp.119-127
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    • 2011
  • The aging population has been increasing in Korea so that it is difficult for people to understand the change of the future society. This study aimed to analyze the characteristics of preliminary retiree's alternative housing preference by providing an accurate information about residential current issues and the seriousness brought by the aging society. It explained the visual information about the aspect of the residential change due to the aging society to 104 preliminary retirees who live in the apartment in Seoul. It surveyed the characteristics of the alternative housing preference following 4 situations of the Old age type(couple/healthy, couple/ill, single/healthy, single/ill). It analyzed the difference of housing preference before and after providing information. The results are as follows: First, a previous apartment is not enough to prepare the aging society and UIBS(unit insertion building system) for the elderly was expected to be a great help to the frail after 2026. Second, the preference of UIBS was increased after providing information of the aging society. Third, in the case of the illness, a big city with medical facilities was preferred not to move in the suburb. Fourth, after providing information, a small size of apartment was preferred but the preferred change of housing ownership was not founded. Last, there was considerable difference before and after providing information under 4 situation of Old age type. These results showed the feasibility of coping with more accurate future society only if a survey should be taken with providing sufficient information about the aging society.

A Comparative study of the funeral culture according to an aging society between Korea and Japan (고령화 사회에 따른 한일 장례문화 비교 연구)

  • Hwang, Kyu-Sung;Bae, Ho-Jung;Choi, Young-Eun;Kim, Jeong-Lae
    • The Journal of the Convergence on Culture Technology
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    • v.1 no.1
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    • pp.69-72
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    • 2015
  • Abstract Social pathologic phenomenon such as low fertility, nuclear family and one person households seems to be on the rise as Korea moves towards being an aging society. We think many trouble is expected to be exit as aging society progresses, but there were few studies about an aging society, especially funeral culture. Appearance of the aging society in Korea similarly follows the course of Japan. So we studied about similar funeral culture of aging society in Japan and prepared for the funeral culture in Korea. This study will suggest a gaze on realistic objective point of view, through the way to illustrate exactly the concept of "funeral for family (家族葬)" among Japanese funeral culture(Syukacheu(終活), Chyokusou(直葬) and funeral for family(家族葬)) and will be expected to be an important guide for leading the funeral culture in Korea occur due to aging in future. And this study will give a chance to ruminate on our's funeral attitude about the deceased's dignity.

Policies and industrial technology trends for senior-friendly foods (고령친화식품의 정책 및 산업기술 동향)

  • Lee, Hyun-Sun;Nam, Young-Joo;Kim, Yang-Eun;Kim, Jong-Chan;Shin, YunJeong;Lee, YoungJin;Heo, Wan
    • Food Science and Industry
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    • v.53 no.4
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    • pp.435-443
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    • 2020
  • Korea has entered into an aged-society in 2018. If this trend continues to increase, it is expected that a super-aging society will take place by 2026. Therefore, Korea is placed in the situation of becoming the world's fastest aging nation as it becomes a super-aging society from an aged-society in twenty-six years. In order to provide an effective supply of nutrition for the socially weak, Japan developed a variety of foods with food texture improvements. Germany improved accessibility for meal service development. Senior-friendly food is a softened food or a highly concentrated drink, which is considered a texture-modified food, for the elderly with eating disorders to digest food more easily by making food particles smaller. Varying food processing techniques such as freeze-thawing enzyme impregnation, high-pressure processing, super-heated steam processing, 3D food print, and others used to produce texture-modified foods.

A Study on Smart Aging System for the Elderly based on Metaverse (고령자를 위한 메타버스 기반의 Smart Aging 시스템의 연구)

  • Cho, Myeon-Gyun
    • Journal of Digital Convergence
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    • v.20 no.2
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    • pp.261-268
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    • 2022
  • Recently, the number of elderly living alone suffering from loneliness and depression is also increasing significantly due to the rapid aging of the population and nuclear families. In this paper, we propose a smart aging system that increases life satisfaction by providing the elderly with the optimal service tailored to the elderly with the help of IT according to their residential environment and health status. It is possible to provide an advanced customized support system for the elderly by fully utilizing IoT, AI, and Metaverse techniques not only for the elderly who want to live an active life in society but also for the elderly who need care in a nursing hospital. The proposed system provides human satisfaction by providing social connection in real space and virtual space in accordance with the residential environment and health status to the elderly suffering from loneliness in hospital (hospital care) facilities and at home. This paper proposes a new path for future-oriented welfare policy for the elderly by providing a user-customized smart aging system by combining AI and Metaverse technology with a rapidly changing social environment.

Influence of Strain Rate on Tensile Properties and Dynamic Strain Aging of an Fe-24.5Mn-4Cr-0.45C Alloy (변형률 속도에 따른 Fe-24.5Mn-4Cr-0.45C 합금의 인장 특성과 동적 변형시효)

  • Lee, Seung-Yong;Hwang, Byoungchul
    • Korean Journal of Materials Research
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    • v.26 no.5
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    • pp.281-286
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    • 2016
  • In the present study, the tensile properties and dynamic strain aging of an Fe-24.5Mn-4Cr-0.45C alloy were investigated in terms of strain rate. During tensile testing at room temperature, all the stress-strain curves exhibited serrated plastic flows related to dynamic strain aging, regardless of the strain rate. Serration appeared right after yield stress at lower strain rates, while it was hardly observed at high strain rates. On the other hand, strain-rate sensitivity, indicating a general relationship between flow stress and strain rate at constant strain and temperature, changed from positive to negative as the strain increased. The negative strain-rate sensitivity can be explained by the Portevin Le Chatelier effect, which is associated with dynamic strain aging and is dependent on the strain rate because it is very likely that the dynamic strain aging phenomenon in high-manganese steels is involved in the interaction between moving dislocations and point-defect complexes.

Development of the Auto-Aging Test Controller for a Hydraulic Motor (유압모터 길들이기 자동시험 제어기 개발)

  • Jung, Gyu Hong;Shin, Dae Young;Seo, Dong Jin
    • Journal of Drive and Control
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    • v.12 no.4
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    • pp.28-34
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    • 2015
  • Because heavy-duty construction vehicles such as excavators are required for good engine-room cooling capacity, a hydraulic gear motor is adopted in the cooling fan drive mechanism to actively control the output speed, instead of adopting the conventional ON/OFF type belt drive. While gear motors are normally limited to 140bars of operating pressure, those for the cooling fan are capable of operating at continuous pressures of up to 220bars. After assembly, all gear motors for high pressure must pass an aging test which is a kind of the wearing process between the gear teeth and motor housing. During the aging process with gradual pressure increments, gear sticking sometimes occurs due to abnormal wear, resulting in defects. This paper focuses on a gear-sticking free aging test controller that is designed together with the knowledge of an experienced operator and the analysis results of experimental data of the gear jamming phenomenon. From the aging experiment, it is demonstrated that the developed controller that can alter the setting pressure of the load pump is effective for stabilizing the abrupt increase in the motor input pressure, thus preventing the hydraulic motor from stopping. This is expected to be helpful for the reduction of defects and increase in productivity.

Effect of Aging Treatment on Pitting Corrosion of Super Duplex Stainless Steel Weld Metal (슈퍼듀플렉스강 용접금속의 공식에 미치는 시효처리의 영향)

  • Lee, Jae-Hyoung;Seo, Gi-Jeong;Jung, Byong-Ho;Kang, Chang-Yong
    • Journal of Power System Engineering
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    • v.18 no.2
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    • pp.70-76
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    • 2014
  • A specimen of weld metal was prepared by GTA welding with weld wire of super duplex stainless steel. Aging treatment was conducted for the sample at the temperature range of 700 to $900^{\circ}C$ for 5 to 300 minutes. The effect of aging temperature and time to pitting corrosion of weld metal has been investigated and the results were derived as follows. The volume fraction of ${\sigma}$ phase tends to increase with an increase of aging temperature and time. Pitting potential Ep representing pitting corrosion was found to tend to decrease with an increase of aging time at 700 to $900^{\circ}C$. And most of the pits formed near the ${\sigma}$-phase in the ferrite and seemed to propagated to austenite.