• 기본간호학회지
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• 제16권2호
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• pp.207-213
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• 2009

Purpose: This study was done to examine how medication contamination in a single-dose glass ampule is affected by minute glass flakes generated in different methods of cutting the ampule. Method: Sixty medication-containing glass ampules were randomly assigned to two groups. The number of glass flakes, resulting from two different cutting methods (with cotton and without cotton), were counted under the microscope. Contamination was evaluated by extracted the medication with a syringe and culturing it in E. coli, coliform, and aerobic bacteria culture media. Result: Fewer glass flakes were found in the ampules when the ampule was cut with cotton. The use of cotton, however, did not significantly change the degree of drug contamination. Conclusion: Although minute glass flakes generated in the ampule cutting operation did not significantly contaminate the medication and the use of cotton decreased the number of glass flakes in the ampules, glass flakes injected into the blood and tissues of the patient remain a risk factor. Therefore, pre-filled syringes or syringes with filters would be alternative methods and safeguards against the possible injection of glass flakes generated while cutting the ampule.

• 한국지하수토양환경학회지:지하수토양환경
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• 제8권2호
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• pp.1-8
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• 2003

Chlorofluorocarbons(CFCs) 조사를 위한 지하수 시료 채취 방법 중 cold-welded copper tube method(구리관법)과 flame-sealed borosilicate glass ampule method(유리앰퓰법)의 두 방법을 비교하고 검토하였다. 구리관법에 의해 채취된 시료의 CFCs 농도는 중복시료간에 재현성이 불량한 반면, 유리앰퓰법은 상대표준오차가 5％ 이내로 좋은 재현성을 보여주었다. 이것은 구리관법을 적용할 때, 관정의 출수구와 구리관의 연결의 밀봉성이 좋지 않았기 때문인 것으로 추정된다. 또한 구리관법에 의한 CFCs 농도는 전체적으로 유리앰퓰에 의한 값보다 높았으며 이러한 특징은 CFC-11이 CFC-12보다 더 두드러졌다. 구리관법의 경우에 플라스틱 관이나 관정에 설치된 출수구에 포함된 고무 패킹 등이 시료를 CFCs로 오염시켰을 것으로 평가된다. 유리앰퓰법을 적용했을 때에는 이러한 가능성을 제거하기 위해 stainless steel과 nylon 재질만을 이용하고, 시료채취장비를 관정의 주배수관에 직접 연결하였다. 인위적인 공급원에 의한 CFCs가 없을 것으로 예상되는 시료에서 유리앰퓰법에 의해 매우 낮은 수준의 CFCs농도가 측정됨으로써 이 시료채취과정의 유효성이 검증되었다.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2002년도 추계학술발표회
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• pp.21-23
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• 2002

Two sampling methods for chlorofluorocarbons(CFCs) in groundwater were compared and assessed with groundwater samples in Jeju Island. CFCs concentrations from copper tube method were widely variable among triplicates and higher than those from flame-sealed glass ampule method. For the copper tube method, this is aggravated by rubber packings in the faucet of discharge line of wells, which was removed for the glass ampule method. The poor reproducibility and apparent contamination of results by copper tube method is due to the improper sealing of copper tubes and materials in water discharge line. This suggests that it is more difficult to achieve complete isolation from the atmosphere in the copper tube method and that materials that could release CFCs should be avoided along the sampling flow lines. It seems that the flame-sealed glass ampule method is more relevant for groundwater sampling for CFCs though it requires more complicated equipments and procedures.

• 대한간호학회지
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• 제36권6호
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• pp.1033-1041
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• 2006

Purpose: Glass particle contamination of the contents of single-dose glass ampules can occur upon opening. Different aspiration techniques, different sizes of needles, different sizes of ampules, and different cutting methods were studied to determine if they had any effect on glass particle contamination. Method: Different aspiration techniques(with filter, without filter), different sizes of needles(18G, 25G), different sizes of ampules(2ml, 20m1), and different cutting methods(with cotton, without cotton) were evaluated. Method: Twenty ampules were randomly assigned in each group. Three slides containing glass particles for each ampule were made and counted under a microscope by 3 study blind persons. Result: The number of glass particle contamination is much less when using a filter rather than without a filter. The number of glass particle contamination is much less when using a 25G needle rather than on 18G needle. The number of glass particle contamination is much less when using 2ml ampules rather than 20m1 ampules. The number of glass particle contamination is much less when using cotton rather than without cotton. Conclusion: It was shown that using a filter, a small size needle, smaller sized ampules and using cotton when cutting the ampule will decrease the risk of parenteral injection of glass particles.

• 대한한의학방제학회지
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• 제17권2호
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• pp.111-121
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• 2009

Objectives : This study was performed to evaluate the efficacy of ampule containing herbal extract(Ulmus davidiana, Ginkgo biloba, Perilla ocymoides, Morus alba, Glycyrrhiza uralensis (licorice), and Angelica gigas) on skin wrinkles in adult women with facial wrinkles. Methods : A total of 12 women, 30 to 46 years of age, with wrinkles in the corner of eyes, applied ampule containing herbal extract twice daily for up to 12 weeks. Silicon replicas of right crow's feet area and antecubital fossa were taken before use of test product and at 4, 8 and 12 weeks. The replicas were analyzed by optical profilometry with Skin Visiometer SV600. The wrinkle and roughness parameters, R1, R2, R3, R4 and R5 were calculated and statistically analyzed. In addition, a subjective evaluation of product efficacy was conducted by patient's assessment. Results : The mean values of all the skin roughness parameters were decreased at 4-week, and decreased significantly at 8 and 12-week except R4 at 12-week after test product use. The subjective evaluation of wrinkle by patient's assessment was also improved. However, one patient noted stiffness of face after use of test product. Conclusions : These study suggested that the application of ampule containing herbal extract twice daily for 12 weeks may effectively improve the facial wrinkles without severe side effect.

• 기본간호학회지
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• 제14권2호
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• pp.166-172
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• 2007

Purpose: The purpose of this study was to examine the factors influencing glass particle contamination in single dose glass ampules upon opening. Method: The study was single case experimental design. Different methods of opening ampule (hand, wooden stick), different sizes of ampules(1cc, 2cc) and different sizes of needles(17gauge, 23gauge, $5{\mu}m$ filter) were evaluated. Eighteen ampules were randomly assigned in each group. The number of glass ampule particles ${\ge}10{\mu}m$ was counted by microscope. Results: There was no significant difference in the number of particles aspirated by opening methods. But number of glass particles was much lower when using 1cc ampules rather than 2cc ampules and was also much lower when using smaller size needles and needles which include a $5{\mu}m$ filter rather than larger size of needles. Conclusion: We suggest that larger bore or unfiltered needles increase the risk of aspirating more glass particles than smaller bore or filter needles. In addition, these data show that a wooden stick can be used as a method opening glass ampules.

• 대한치과마취과학회:학술대회논문집
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• 대한치과마취과학회 2001년도 제1차 학술대회
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• pp.63-63
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• 2001

• Bulletin of the Korean Chemical Society
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• 제29권9호
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• pp.1787-1789
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• 2008

• Applied Biological Chemistry
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• 제38권6호
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• pp.512-515
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• 1995

동결건조후 재수화 방법이 Streptomyces aureofaciens 생존도에 미치는 영향을 실험하기 위해 $^3H-adenine$을 DNA에 주입시킨후 유출되는 방사선량과 균을 전자현미경으로 관찰하였다. 그 결과 Streptomyces aureofaciens의 손상은 동결건조 과정에서 일어나는것 보다 재수화 과정에서 공기를 허용한 상태에서 재수화시 크게 일어났으며, 그 생존도는 약 20%이고, 공기가 없는 밀봉된 진공상태의 이중 용기에서 재수화시 약 91%로 나타났다. 공기를 허용한 개봉된 이중 용기에서 증류수에 잠긴채 재수화한 생존도는 약 36%이며, 이중 용기에 $N_2-gas$를 주입하여 밀봉된 상태에서 재수화한 경우 약 83% 생존도를 나타냈다. 따라서 생존도는 재수화 과정에서 산소의 영향을 매우 크게 받는 것으로 나타났다.

• 한국초전도ㆍ저온공학회논문지
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• 제16권3호
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• pp.1-3
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• 2014

We have synthesized La doped $CaFe_2As_2$ single crystals with Sn flux in an evacuated quartz ampule. Doping and pressure effects on the magnetic and superconducting properties of the under-doped $Ca_{1-x}La_xFe_2As_2$ (x=0.08, 0.1) were studied by measuring electrical resistivity under quasi-hydrostatic pressure up to 21 kbar. Magnetic transition temperatures for all studied concentrations were sharply suppressed with slight amplitude of pressure, less than 3 kbar, while superconducting transition temperatures were robust against pressure. In this communication, we report temperature-pressure phase diagram for the La-doped $CaFe_2As_2$ single crystals.