• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2162-2190
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• 2007

The newly-developed Meerwein-Ponndorf-Verley (MVP) type reagents using aluminum, boron and other metals for reduction of organic functional groups such as carbonyl and epoxy compounds have been surveyed. highlighted and reviewed in this account are the appearance of new MPV type reagents and their application to the selective reduction of organic functions. Finally, this account emphasizes the distinct contrast in the reducing characteristics existed between metal hydride reagents and MPV reagents, and compares their usefulness in organic synthesis.

• Bulletin of the Korean Chemical Society
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• v.32 no.6
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• pp.1808-1846
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• 2011

From 1975 to 2011, for thirty six years, the author and his collaborators have developed a variety of reducing and hydroborating agents, and applied them to organic synthesis, which involves the 1,2-reduction of ${\alpha}$,${\beta}$-unsaturated carbonyl compounds, stereoselective reduction of cycloalkanones, regioselective ring-opening of epoxides, partial reduction of carboxylic acid derivatives to aldehydes, regioselective addition to carbon-carbon multiple bonds, etc. by utilizing metal hydrides and the newly-devised the Meerwein-Ponndorf-Verley (MPV) type reagents. Such developments provide a new synthetic methodology making possible valuable selective reductions and hydroborations, not practical previously.