• Title/Summary/Keyword: Alternative test method

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Study on the Design Method Development of Crash Cushion Using Single Degree of Freedom (단자유도계를 이용한 충격흡수시설의 설계법 개발)

  • Joo, Jae-Woong;Kim, Ki-Jung;Jang, Dae-Young;Son, Seung-Neo
    • International Journal of Highway Engineering
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    • v.9 no.3
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    • pp.91-100
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    • 2007
  • The most important thing for driver's safety on the road is equipment of crash cushion as a vehicle protection safety facility. But development of crash cushion is defective because there's no rational and reality way of design. And also without an alternative plan, it rely on crash test hereby it suffers a great economic loss and wastes time. This study that uses data of cash test proves the suitability of single degree of freedom which considers the safety of passengers about three-dimensional complicated Crash Analysis. As the study analyzes the conduct of crash cushion, it want to develop the effective method of design on Single Degree of Freedom Crash Cushion. And it presents the way of crash cushion design through making a crash analysis model with single degree of freedom. To verify the validness of the crash cushion plan, with single degree of freedom plan, we make the level CC2 crash cushion and execute the crash test. A performance test brings satisfied result and a plan of single degree of freedom crash cushion is proven as an one of the way to be a good system which can design crash cushion.

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A Comparative Analysis and Improvement of the Fractional Distillation Experiments in the Middle School Science Textbooks (중학교 과학 교과서 분별 증류 실험의 비교 분석 및 개선)

  • Ryu, Oh Hyun;Choi, Moon Young;Song, Ju Hyun;Kwon, Jung Geun;Paik, Seoung Hey;Park, Kuk Tae
    • Journal of the Korean Chemical Society
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    • v.45 no.5
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    • pp.481-490
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    • 2001
  • The purpose of this study was to find out the problems on the fractional distillation experiments in the middle school science textbooks based on the 6th curriculum and to suggest an efficient experiment method for the middle school students. The first step was the classification of the experiments in 8 science textbooks according to heating apparatus and liquid mixtures. The second step was doing each experiment 3 times followed by the experimental process in the textbooks. The third step was developing the alternative experiments for solving the problems found in the second step. The heating method used in the alternative experiments were direct heating, oil bath, and heating mantle. The results of the second step showed that the direct heating experiment of branched round flask was more close to the theoretical prediction than the experiment of water bath heating of branched test tube. Also the direct heating experiment of thermally insulated branched round flask was better than the result of the experiment which was not insulated. The results of the third step showed that the experiment using heating mantle regulated heating power by observing the temperature of distillate gave the closest result to the theoretical prediction. From the above results, it is concluded that the experiment using branched test-tube with water bath heating is not adequate for the fractional distillation and an alternative experiment using insulated branched round flask with heating mantle regulated heating power during experiment is recommended.

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Specimens and method for evaluating the moisturizing ability of lip makeup products (립메이크업 제품의 보습능 평가용 시편과 측정법)

  • Sung, Jee Eun;Jung, Jung Hui;Ryu, Hee-Wook
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.727-736
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    • 2017
  • In this study, the method of evaluation of moisturizing ability of cosmetics using specimens was studied as an alternative method of clinical tests. Cosmetic spreadability, surface drying, and moisture loss rate of four specimens (Japanese cake (Maru mochi), Garaetteok, wheat flour, and agar) were evaluated. Also, the water loss rate of the specimens and the transepidermal waterloss were analyzed for 10 kinds of lip make-up products (5 kinds of lipstick, 3 kinds of lip balm, 2 kinds of lip gloss). The moisture loss rate (moisture evaporation sensitivity) of the agar specimen was highest in the order of agar> Garaetteok> Japanese cake> wheat flour. Agar specimens are the most suitable in terms of spreadability, surface crack, and raw material supply. Containers for the preparation of agar specimens are suitable for plastic materials with low heat transfer, which can produce convex, smooth surface specimens. In the evaluation of moisturizing ability of lip makeup products, there was a strong correlation between the water loss rate and the transepidermal waterloss rate measured with agar specimens. These results show that the proposed method can be used as one of the useful alternative test methods.

Phototoxicity Evaluation of Pharmaceutical Substances with a Reactive Oxygen Species Assay Using Ultraviolet A

  • Lee, Yong Sun;Yi, Jung-Sun;Lim, Hye Rim;Kim, Tae Sung;Ahn, Il Young;Ko, Kyungyuk;Kim, JooHwan;Park, Hye-Kyung;Sohn, Soo Jung;Lee, Jong Kwon
    • Toxicological Research
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    • v.33 no.1
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    • pp.43-48
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    • 2017
  • With ultraviolet and visible light exposure, some pharmaceutical substances applied systemically or topically may cause phototoxic skin irritation. The major factor in phototoxicity is the generation of reactive oxygen species (ROS) such as singlet oxygen and superoxide anion that cause oxidative damage to DNA, lipids and proteins. Thus, measuring the generation of ROS can predict the phototoxic potential of a given substance indirectly. For this reason, a standard ROS assay (ROS assay) was developed and validated and provides an alternative method for phototoxicity evaluation. However, negative substances are over-predicted by the assay. Except for ultraviolet A (UVA), other UV ranges are not a major factor in causing phototoxicity and may lead to incorrect labeling of some non-phototoxic substances as being phototoxic in the ROS assay when using a solar simulator. A UVA stimulator is also widely used to evaluate phototoxicity in various test substances. Consequently, we identified the applicability of a UVA simulator to the ROS assay for photoreactivity. In this study, we tested 60 pharmaceutical substances including 50 phototoxins and 10 non-phototoxins to predict their phototoxic potential via the ROS assay with a UVA simulator. Following the ROS protocol, all test substances were dissolved in dimethyl sulfoxide or sodium phosphate buffer. The final concentration of the test solutions in the reaction mixture was 20 to $200{\mu}M$. The exposure was with $2.0{\sim}2.2mW/cm^2$ irradiance and optimization for a relevant dose of UVA was performed. The generation of ROS was compared before and after UVA exposure and was measured by a microplate spectrophotometer. Sensitivity and specificity values were 85.7% and 100.0% respectively, and the accuracy was 88.1%. From this analysis, the ROS assay with a UVA simulator is suitable for testing the photoreactivity and estimating the phototoxic potential of various test pharmaceutical substances.

A Bootstrap Method for Analysis of Noise & Vibration Spectrum (부트스트랩 기법을 이용한 소음진동 스펙트럼 분석법 소개)

  • Chun, Young-Doo;Park, Jong-Chan;Chung, Eui-Seung
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.185-188
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    • 2008
  • This paper introduces the Bootstrap method for statistical analysis of noise and vibration spectrum in aeronautic and space fields. Generally, all components of a launch vehicle and its payloads are subjected to high intensive noise and vibration environment during the lift-off phase and the ascent phase through Mach =1 and Max Q. In order to verify their survivabilities against these severe vibroacoustic environments during qualification tests and acceptance tests, it is most important to estimate the proper upper limits of the environmental condition. Although NASA has typically utilized the Normal Tolerance Limit method in deriving these levels, the reference[1] says that the Bootstrap can be also an alternative method to estimate the maximum expected environments. In this paper, a general procedure of the Bootstrap method is summarized, and it is applied to analyze acceleration power spectral density functions, which were measured during acoustic test on the upper stage of KSLV-I.

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Comparison of Sensitivity Analysis Methods for Building Energy Simulations in Early Design Phases: Once-at-a-time (OAT) vs. Variance-based Methods

  • Kim, Sean Hay
    • KIEAE Journal
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    • v.16 no.2
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    • pp.17-22
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    • 2016
  • Purpose: Sensitivity analysis offers a good guideline for designing energy conscious buildings, which is fitted to a specific building configuration. Sensitivity analysis is, however, still too expensive to be a part of regular design process. The One-at-a-time (OAT) is the most common and simplest sensitivity analysis method. This study aims to propose a reasonable ground that the OAT can be an alternative method for the variance-based method in some early design scenarios, while the variance-based method is known adequate for dealing with nonlinear response and the effect of interactions between input variables, which are most cases in building energy simulations. Method: A test model representing the early design phase is built in the DOE2 energy simulations. Then sensitivity ranks between the OAT and the Variance-based methods are compared at three U.S. sites. Result: Parameters in the upper rank by the OAT do not much differ from those by the Main effect index. Considering design practices that designers would chose the most energy saving design option first, this rank similarity between two methods seems to be acceptable in the early design phase.

An Experimental Verification on the Development of an Innovative Diamond Wire Saw Cutting Technology (새로운 다이아몬드 와이어 쏘 절단 기술 개발에 관한 실험적 검증)

  • Park, Jong Hyup;Chu, Baeksuk
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.17 no.6
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    • pp.83-90
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    • 2018
  • This paper introduces a innovative diamond wire saw cutting technology and its experimental verification that can be utilized for cutting heavy structures. While conventional diamond wire saw cutting technologies such as water cooled cutting method and dry cutting method cause severe environmental problems due to generating massive concrete sludge or dust scattering, the proposed method can eliminate those problems considerably. Through extensive experiments using heavy structure test bed and real bridge pier structure, comprehensive analysis and comparative evaluation about various cutting methods were performed. As a result, the innovative diamond wire saw cutting method could achieve a similar cutting and cooling performance to the water cooled cutting method without generating concrete sludge and it showed an improved cutting and cooling performance to the dry cutting method without dust scattering. Consequently it is confirmed that the suggested cutting technology can be a promising environment-friendly alternative in the field of heavy structure dismantling.

Evaluation of Larynx Cancer via Chemometrics Assisted Raman Spectroscopy

  • Senol, Onur;Albayrak, Mevlut
    • Current Optics and Photonics
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    • v.3 no.2
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    • pp.150-153
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    • 2019
  • Larynx cancer is a potentially terminal and severe type of neck and head cancer in which malignant cells start to grow and spread upwards in the larynx, or voice box. Smoking tobacco, drinking hot beverages and drinking alcohol are the main risk factors for these tumors. In this study, we aimed to develop a precise, accurate and rapid chemometrics assisted Raman spectroscopy method for diagnosis of larynx cancer in deparaffinized tissue samples. In the proposed method, samples were deparaffinized and 20 microns of each tissue were located on a coverslip. Both healthy (n = 13) and cancerous tissues (n = 13) were exposed to a Raman laser (785 nm) and excitations were recorded between wavenumbers of $50{\sim}1500cm^{-1}$. An Orthogonal Partial Least Square algorithm was applied to evaluate the Raman spectrum obtained. Sensitivity and specificity of the proposed method is high enough with the aid of Principal Component Analysis (PCA) to test the whole model. Healthy and cancerous tissues were accurately and precisely clustered. A rapid, easy and precise diagnosis algorithm was developed for larynx cancer. By this method, some useful data about differences in biomolecules of each group (phospholipids, amides, tyrosine, phenylalanine collagen etc.) was also obtained from the spectra. It is claimed that the optimized method has a great potential for clustering and separating tumor tissues from healthy ones. This novel, rapid, precise and objective diagnosis method may be an alternative for the conventional methods in literature for diagnosis of larynx cancer.

DEVELOPMENT OF CONCRETE FILLED TUBE AS A PILLAR PILE FOR TOP DOWN METHOD

  • Jee-Yun Song;Hong-Chul Rhim;Seung-Weon Kim
    • International conference on construction engineering and project management
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    • 2009.05a
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    • pp.808-813
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    • 2009
  • Top-down method is widely used for urban area construction for its advantages in reducing environmental problems such as dust and noise, and saving construction cost depending on given conditions of a construction site. Because the excavation and construction of super- and sub-structures of the building have to be proceeded simultaneously, a column has to be embedded prior to excavation. This column is called a pillar column or pre-founded column. Usually a wide flange section is used for these columns. To place the columns, usually the diameter of casing holes needs to be larger than the section of the wide flange itself in order to accommodate a couple of tremie pipes for pouring concrete. In this paper, a newly developed method of using circular pipe as an alternative to the existing wide flange section is discussed. The crucial part of the new method is to develop a connection between the circular column and concrete flat slabs. For shear force transfer from concrete slab to the concrete filled tube (CFT) column, shear jackets with studs and shear bands are proposed. The studs are welded on the jackets at shop and placed around the circular column on site. The shear bands are welded on the outer side of the CFT at shop and inserted into ground with the CFT. Test results and application of the method to a construction site are also provided in this paper.

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CCQC modal combination rule using load-dependent Ritz vectors

  • Xiangxiu Li;Huating Chen
    • Structural Engineering and Mechanics
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    • v.87 no.1
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    • pp.57-68
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    • 2023
  • Response spectrum method is still an effective approach for the design of buildings with supplemental dampers. In practice, complex complete quadratic combination (CCQC) rule is always used in the response spectrum method to consider the effect of non-classical damping. The conventional CCQC rule is based on exact complex mode vectors. Sometimes the calculated complex mode vectors may be not excited by the external loading and errors in the structural responses always arise due to the mode truncation. Load-dependent Ritz (LDR) vectors are associated with the external loading and LDR vectors not excited can be automatically excluded. Also, contributions of higher modes are implicitly contained in the LDR vectors in terms of static responses. To improve the calculation efficiency and accuracy, LDR vectors are introduced in the CCQC rule in the present study. Firstly, the generation procedure of LDR vectors suitable for non-classical damping system is presented. Compared to the conventional LDR vectors, the LDR vectors herein are complex-valued and named as complex LDR (CLDR) vectors. Based on the CLDR vectors, the CCQC rule is then rederived and an improved response spectrum method is developed. Finally, the effectiveness of the proposed method in this paper is verified through three typical non-classical damping buildings. Numerical results show that the CLDR vector is superior to the complex mode with the same number in the calculation. Since the generation of CLDR vectors requires less computational cost and storage space, the method proposed in this paper offers an attractive alternative, especially for structures with a large number of degrees of freedom.