• Title/Summary/Keyword: Alternative test method

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ASSESSMENT OF LOCAL LYMPH NODE ASSAY AS AN ALTERNATIVE METHOD FOR SKIN SENSITIZATION POTENTIAL

  • Hwang, In-Chang;Kim, Hyung-Soo;Dong, Mi-Sook;Park, Jae-Hyun;Lee, Jong-Kwon;Oh, Hye-Young;Park, Young-In
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.194-194
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    • 2001
  • Preclinical test methods for allergenic potential chemicals has been widely used to assess human risks and has been developed. Recently, the murine local lymph node assay (LLNA) has been proposed as a prospective method to identify contact allergens and to replace conventional the guinea pig maximization test (GPMT). The objective of this study was to establish LLNA and to evaluate allergenicity of chemicals by LLNA. (omitted)

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Transmission System Expansion Planning Using Branch and Bound (분기 한정법에 의한 송전계통의 확충 계획)

  • Tran, Trungtinh;Kang, Sung-Rok;Kim, Kuen-Ho;Lee, Ji-Hoon;Choi, Jae-Seok
    • Proceedings of the KIEE Conference
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    • 2003.07a
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    • pp.46-49
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    • 2003
  • This paper proposes a method to solve expansion problem for a transmission network, given future generation and load strategy, and alternative types of lines available, subject to load, reliability and right of way constraints, the problem is formulated as a series of zero one integer programs which are solved by an efficient branch and bound algorithm A study test result on the 63-buses test system shows that the proposed method is practical and efficiently applicable to the transmission expansion planning.

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초고강도 콘크리트의 재료특성 및 휨 거동에 관한 실험적 연구

  • 장일영;이호범
    • Proceedings of the Korea Concrete Institute Conference
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    • 1991.10a
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    • pp.107-112
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    • 1991
  • The object of this study is to investigate material characteristics and flexural behavior of high strength concrete. Principal causes of variations of high compressive strength include the strength-producing capabilities of cement and silica hume. Compressive strength of 1200 kgf/$\textrm{cm}^2$ is introduced for identifying the effect of the variation of the size of porocity and alternative method of measurement, Acoustic Emition method, is applied to examine the phenominon of concrete failure. The main test variables in the beam element are tensile steel ratios, presence of shear reinforcement, and change of steel shape. The estimation of stress block in the flexural test of this element tends to support the present theory and may suggest a desirable shape of the stress block.

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A Study on Climacteric Symptoms Corresponding to the Use of Complementary and Alternative Therapy in the Middle Aged Women (중년여성의 보완대체요법 이용양상에 따른 갱년기 증상에 관한 연구)

  • Park, Hyoung-Sook;Kim, Young-Hee;Lee, Yun-Mi
    • Journal of Korean Biological Nursing Science
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    • v.8 no.1
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    • pp.23-37
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    • 2006
  • Purpose: This study was performed to identify climacteric symptoms corresponding to the use of complementary and alternative therapy(CAT) in middle aged women. Method: The subjects of the study were 603women(40-64years) and were chosen by convenient sampling from 1 April to 31 July 2004. The collected data was analyzed using descriptive statics, chi-square, t-test analysis by SPSS/WIN program. Results: 1. It was shown that 63.8% of subjects have utilized one or more types of CAT. 2. It was shown that the most frequently used types are health supplement(40.5%), gold acupuncture(31.2%), acupress(24.7%), hand acupuncture(21.8%) 3. There was significant difference in the using experience CAT by religion(p=.029), job(p=.018), hormone replacement(p=.016), exercise(p=.007), health state(p=.013). 4. There was significant difference in climacteric symptoms(p=.000) corresponding to the using experience of CAT. 5. There was significant difference in climacteric symptoms(p=.028) corresponding to the using experience hand therapy of CAT. Conclusion: We found that middle aged women used CAT more than others populations. Future research examining the determinants of CAT use, incorporating attitudinal and health conditions, as well as clinical efficacy, effectiveness, and health outcome studies of specific CAT therapies are warranted.

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Bias and Accuracy of Single Milking Testing Schemes to Estimate Daily Milk (검정일 1회 검정에 의한 착유우의 1일 유량 추정시 오차와 정확도)

  • Cho, Y.M.;Ahn, B.S.;Choi, Y.L.
    • Journal of Animal Science and Technology
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    • v.45 no.5
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    • pp.725-730
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    • 2003
  • This study was conducted to evaluate the adequacy of an alternative a.m.-p.m. testing scheme for milk yield in comparison with the official test method based on weighing two milkings within 24 h. A total of 8,309 p.m. milking weights and 6,767 a.m. milking weights from 72 Holstein cows raised at N.L.R.I. were collected between October 2000 and November 2001. Ratios were computes for daily milk yield to a.m. and p.m. milking weights(direct yield ratios) and ratios of a.m. and p.m. milking weights to daily milk yield (inverse yield ratios). Analysis of variance indicated that the milking interval is the most important source of variation for yield ratios. Adjustment factors for estimating daily milk yield from single milking weights were derived through regression analysis of direct and inverse yield ratios on the length of the milking interval. Daily milk yield was estimated more precisely and accurately when adjustment factors were used than when single milking weights were doubled. In conclusion, alternative recording of a.m. and p.m. milking weights led to reliable estimates of milk yields.

Alternative Methods for Classification on Weathered Strata (풍화토층의 구분을 위한 시험법의 적용)

  • Son, Young-Hwan;Noh, Soo-Kack;Kim, Seong-Pil;Chang, Pyoung-Wuck
    • Journal of The Korean Society of Agricultural Engineers
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    • v.51 no.3
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    • pp.63-69
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    • 2009
  • The undisturbed specimens used in this research were sampled in the field by the sequential sampling method. In addition, four testing methods were applied to identify for the characteristics and classification of weathered strata. N-value by standard penetration test was obtained from in the field and then analyzed using normalization method. Other methods such as X-ray grain size distribution, X-ray fluorescence spectroscopy(XRF), and fall cone test were carried out in the lab. These analyzed results indicate that distribution of particle, composition of minerals are changed in accordance with the degree of weathering, unusual strata and depth. Consequently, the weathered strata can be extensively separated into two parts according to the test results and each part was shown different in the strata characteristics. It can be prospected that mechanical characteristics should be different, even though mechanical tests were not applied. Furthermore, these results not only make up for the error by one testing method but also contribute more effectively and economically to the design and the construction.

Utilization of Alternative Complementary Remedies of Stroke Patients (뇌졸중 환자의 보완대체요법 이용실태)

  • Mok, Soon Ak;Cho, Myoung Ok
    • Korean Journal of Adult Nursing
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    • v.16 no.3
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    • pp.432-441
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    • 2004
  • Purpose: This descriptive survey was conducted to investigate out the utilization of alternative complementary remedies for stroke patients. Method: The subject for this study were 194 patients, selected from inpatients department of 11 major medical center at Busan and Ulsan. Data were collected from August 19th to November 12th, 2002 through interview schedule designed by the investigator. Data was analyzed with frequency, percentage, and ${\chi}^2$-test by using SPSS Win 10.0. Results: 71.6% of objects has used alternative complementary remedies. The use of alternative complementary remedies according to disease-related features was statistically significant in concurrent diseases(${\chi}^2=15.03$, p=0.001), rehabilitation treatment(${\chi}^2=6.341$, p=0.012) and the level of ADL(${\chi}^2=19.63$, p=0.000). The most frequently used therapies were diet and nutrition(31.8%). The patients with less than 3month onset and in the mid-period of treatment frequently used remedies. The reason for using remedies were the belief in it's effects on treatment, but most patients responded was not effective(30.9%) or not much improvement after using remedies. Most of the patients were recommended to use remedies by their neighbors(27.3%) and family members(25.2%). The family members were most supportive in therapy(56.1%). The 28.1% of patients responded that the remedies were effective in promoting blood circulation and 95% of the patients had not experienced side effects. Conclusion: These results could be the basic material in developing nursing intervention for cerebral apoplexy patients.

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Effects of Alternative Planting of Cultivars on Photosynthetic Ability and Yield in Soybean (콩 품종 교호재배가 광합성능력 및 수량에 미치는 영향)

  • Kim Ik Je;Son Seok Yong;Ryu In Mo;Lee Ki Yeol;Yun Tae;Lee Cheol Hee;Park Seong Kyu
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.50 no.6
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    • pp.411-414
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    • 2005
  • The purpose of this study was to determine proper method for alternative row culture of two varieties to increase seed yield in soybean. The test varieties 'Hwangkeumkong' and 'Taekwangkong' which were planted monoculture of each variety, seeding after mixing same number of seeds of two varieties, 1-row alternation, 2­row alternation, 2-row 'Hwangkeumkong' and 1-row 'Taekwangkong' and 1-row 'Hwangkeumkong' and 2­row 'Taekwangkong'. Alternative planting of 1-row 'Hwangkeumkong' and 1-row 'Taekwangkong' resulted the highest canopy height and reduced lodging most effectively. The terminal and the 9th leaves of 'Taekwangkong' in alternative variety planting showed the higher photosynthetic ability than pure stand of that. Alternative planting of two varieties in every other row increased yield by $17\%$ in 'Hwangkeumkong' and by $8\%$ in 'Taekwangkong'.

Feasibility of On-chip Detection of Endotoxin by LAL Test

  • Lee, Eun-Kyu;Suh, Chang-Woo;Hwang, Sang-Youn;Park, Hyo-Jin;Seong, Gi-Hoon;Ahn, Yoo-Min;Kim, Yang-Sun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.2
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    • pp.132-136
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    • 2004
  • The LAL (Limulus amebocyte lysate) test for the detection and quantification of endotoxin is based on the gelation reaction between endotoxin and LAL from a blood extract of Limulus polyphemus. The test is labor intensive, requiring dedicated personnel, a relatively long reaction time (approximately 1 h), relatively large volumes of samples and reagents and the detection of the end-point is rather subjective. To solve these problems, a miniaturized LOC (lab-on-a-chip) prototype, 62mm (L) ${\times}$ 18 mm (W), was fabricated using PDMS (polydimethylsiloxane) bonded to glass. Using this prototype, in which 2mm (W) ${\times}$ 44.3mm (L) ${\times}$ 100 $\mu\textrm{m}$ (D) microfluidic channel was constructed, turbidometric and chromogenic assay detection methods were compared, and the chromogenic method was found the most suitable for a small volume assay. In this assay, the kinetic-point method was more accurate than the end-point method. The PDMS chip thickness was found to be minimized to around 2 mm to allow sufficient light transmittance, which necessitated the use of a glass slide bonding for chip rigidity. Due to this miniaturization, the test time was reduced from 1 h to less than 10 min, and the sample volume could be reduced from 100 to ca. 4.4 ${\mu}$L. In summation, this study suggested that the LOC using the LAL test principle could be an alternative as a semi-automated and reliable method for the detection of endotoxin.

Robust Inference for Testing Order-Restricted Inference

  • Kang, Moon-Su
    • The Korean Journal of Applied Statistics
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    • v.22 no.5
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    • pp.1097-1102
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    • 2009
  • Classification of subjects with unknown distribution in small sample size setup may involve order-restricted constraints in multivariate parameter setups. Those problems makes optimality of conventional likelihood ratio based statistical inferences not feasible. Fortunately, Roy (1953) introduced union-intersection principle(UIP) which provides an alternative avenue. Redescending M-estimator along with that principle yields a considerably appropriate robust testing procedure. Furthermore, conditionally distribution-free test based upon exact permutation theory is used to generate p-values, even in small sample. Applications of this method are illustrated in simulated data and read data example (Lobenhofer et al., 2002)