• Title/Summary/Keyword: Alternative methods

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An alternative method for estimating lognormal means

  • Kwon, Yeil
    • Communications for Statistical Applications and Methods
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    • v.28 no.4
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    • pp.351-368
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    • 2021
  • For a probabilistic model with positively skewed data, a lognormal distribution is one of the key distributions that play a critical role. Several lognormal models can be found in various areas, such as medical science, engineering, and finance. In this paper, we propose a new estimator for a lognormal mean and depict the performance of the proposed estimator in terms of the relative mean squared error (RMSE) compared with Shen's estimator (Shen et al., 2006), which is considered the best estimator among the existing methods. The proposed estimator includes a tuning parameter. By finding the optimal value of the tuning parameter, we can improve the average performance of the proposed estimator over the typical range of σ2. The bias reduction of the proposed estimator tends to exceed the increased variance, and it results in a smaller RMSE than Shen's estimator. A numerical study reveals that the proposed estimator has performance comparable with Shen's estimator when σ2 is small and exhibits a meaningful decrease in the RMSE under moderate and large σ2 values.

Poultry Coccidiosis-A Concurrent Overview on Etiology, Diagnostic Practices, and Preventive Measures

  • Nawarathne, Shan Randima;Yu, Myunghwan;Heo, Jung Min
    • Korean Journal of Poultry Science
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    • v.48 no.4
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    • pp.297-318
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    • 2021
  • Coccidiosis is a major parasitic disease in the poultry industry, with great economic implications worldwide. It is a ubiquitous protozoan infection caused by several species of the genus Eimeria (host-specific) that colonize and reproduce in the intestine of birds, ultimately altering the health and performance of the flock. At present, several methods are used to diagnose coccidiosis in poultry, including field and laboratory techniques (intestinal lesion scoring, oocyst counting in feces, and biochemical and molecular diagnosis). Traditionally, diagnosed flocks have been treated either by vaccination to improve the active immunity of the birds against coccidiosis or supplementation of prophylactic anticoccidials to ameliorate the deleterious effects of coccidiosis. However, these methods has certain drawbacks such as vaccine-induced coccidiosis, drug resistance, and residual drug accumulation in the host. Consequently, alternative safe anti-coccidial agents, including the use of phytogenic compounds, have been explored for preventing coccidiosis. Here, we provide a simple overview of the literature on poultry coccidiosis by focusing on the etiology, diagnostic practices, and preventive measures.

A Practical Alternative to Constitutional Medicine - The Non-local Meaning of the Life Structure Diagram and its Application - (체질의학(體質醫學)의 실용적(實用的) 대안(對案) - 생명구조도(生命構造圖)의 비국소적(非局所的) 의미(意味)와 응용(應用) -)

  • Lee, Byung-seo
    • Journal of Korean Medical classics
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    • v.35 no.2
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    • pp.17-32
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    • 2022
  • Objectives : To overcome limitations of previous diagnostic systems and constitutional medicine by suggesting a new perspective of constitutional medicine and a system of Yin Yang and Five Phases that is applicable to many diseases untreatable by biomedicine. Methods : The Life Structure Diagram which shows the different distribution of Yin Yang and Five Phases according to constitution, reflects the non-local and simultaneous characteristics of Yin Yang and Five Phases. It overcomes previous diagnostic systems and constitutional medicine which were local and segmented. Each constitutional types were determined through their defining deep fractal pulse patterns, for which appropriate acupuncture methods and formulas were suggested. Results & Conclusions : A more effective differentiation of constitution and treatment could be achieved through the Life Structure Diagram, which could overcome limitations of pre-existing diagnosis and treatments of Korean Medicine.

Analysis of Regulatory Guidance on Electromagnetic Interference of Equipment for Safety of Nuclear Power Plants (원자력발전소 안전을 위한 전자파장해 검증 규제지침 분석)

  • Park, Jae Yoon;Ah, In Beom;Kim, Jaehyun;Choo, Jaeyul
    • Journal of the Korean Society of Safety
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    • v.37 no.5
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    • pp.74-79
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    • 2022
  • This study analyzes the contents of the second revised Regulatory Guide 1.180 (Revision 2) for electromagnetic compatibility qualification published by the U. S. Nuclear Regulatory Commission by comparing them with those of the previous version. The methods and acceptance criteria of both CE101 and CE102 tests pertaining to conductive emission and RE102 test for radiation emission are observed to have been modified in Revision 2. Furthermore, the revised guide is found to afford flexibility in using alternative methods for electromagnetic interference qualification by allowing the combination of different technical base standards.

Trends in MEA-based Neuropharmacological Drug Screening (MEA 기반 신경제약 스크리닝 기술 개발 동향)

  • Y.H. Kim;S.D. Jung
    • Electronics and Telecommunications Trends
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    • v.38 no.1
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    • pp.46-54
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    • 2023
  • The announcement of the US Environmental Protection Agency that it will stop conducting or funding experimental studies on mammals by 2035 should prioritize ongoing efforts to develop and use alternative toxicity screening methods to animal testing. Toxicity screening is likely to be further developed considering the combination of human-induced pluripotent-stem-cell-derived organ-on-a-chip and multielectrode array (MEA) technologies. We briefly review the current status of MEA technology and MEA-based neuropharmacological drug screening using various cellular model systems. Highlighting the coronavirus disease pandemic, we shortly comment on the importance of early prediction of toxicity by applying artificial intelligence to the development of rapid screening methods.

Different estimation methods for the unit inverse exponentiated weibull distribution

  • Amal S Hassan;Reem S Alharbi
    • Communications for Statistical Applications and Methods
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    • v.30 no.2
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    • pp.191-213
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    • 2023
  • Unit distributions are frequently used in probability theory and statistics to depict meaningful variables having values between zero and one. Using convenient transformation, the unit inverse exponentiated weibull (UIEW) distribution, which is equally useful for modelling data on the unit interval, is proposed in this study. Quantile function, moments, incomplete moments, uncertainty measures, stochastic ordering, and stress-strength reliability are among the statistical properties provided for this distribution. To estimate the parameters associated to the recommended distribution, well-known estimation techniques including maximum likelihood, maximum product of spacings, least squares, weighted least squares, Cramer von Mises, Anderson-Darling, and Bayesian are utilised. Using simulated data, we compare how well the various estimators perform. According to the simulated outputs, the maximum product of spacing estimates has lower values of accuracy measures than alternative estimates in majority of situations. For two real datasets, the proposed model outperforms the beta, Kumaraswamy, unit Gompartz, unit Lomax and complementary unit weibull distributions based on various comparative indicators.

Meta Analysis on the Trade Settlement Study and Research Outlook (무역결제 분야 연구의 메타분석과 전망)

  • Hee-Jung Yeo
    • Korea Trade Review
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    • v.46 no.2
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    • pp.371-387
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    • 2021
  • This paper analyzed 110 papers related to the field of trade settlement published in the Korea Trade Review for 40 years from 1980 to 2019. This study tried to provide an insight on research topics and to suggest future research directions. The papers were analyzed according to the detailed topics of trade settlement. Research trends were identified every ten years by investigating the most frequently used titles and keywords. The analysis found that the direction of the research changed in line with the changes in trade settlement practices. Future research lies in the field of electronicization of traditional settlement methods, search for alternative settlement methods, individual international microtransaction and trade fraud.

Finite element modeling of reinforced and prestressed concrete panels under far-field blast loads using a smeared crack approach

  • Andac Lulec;Vahid Sadeghian;Frank J. Vecchio
    • Computers and Concrete
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    • v.33 no.6
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    • pp.725-738
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    • 2024
  • This study presents a macro-modeling procedure for nonlinear finite element analysis of reinforced and prestressed concrete panels under blast loading. The analysis procedure treats cracked concrete as an orthotropic material based on a smeared rotating crack model within the context of total-load secant stiffness-based formulation. A direct time integration method compatible with the analysis formulation is adapted to solve the dynamic equation of motion. Considerations are made to account for strain rate effects. The analysis procedure is verified by modeling 14 blast tests from various sources reported in the literature including a blast simulation contest. The analysis results are compared against those obtained from experiments, simplified single-degree-of-freedom (SDOF) methods, and sophisticated hydrocodes. It is demonstrated that the smeared crack macro-modeling approach is a viable alternative analysis procedure that gives more information about the structural behavior than SDOF methods, but does not require detailed micro-modeling and extensive material characterization typically needed with hydrocodes.

Effects of Collection Methods on Recovery Efficiency, Maturation Rate and Subsequent Embryonic Developmental Competence of Oocytes in Holstein Cow

  • Wang, Zheng-guang;Yu, Song-dong;Xu, Zi-rong
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.4
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    • pp.496-500
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    • 2007
  • Holstein cow ovaries obtained at a slaughterhouse were used to study the influence of the oocyte collection methods (slicing, puncture, aspiration I and II) on recovery efficiency and subsequent in vitro maturation and embryonic development competence of immature oocytes recovered. In the slicing method, the whole ovarian was chopped into small pieces with a surgical blade. In the puncture method, the whole ovarian surface was punctured by 18-g needle. In other 2 aspiration methods, collected oocytes by aspirating from the visible follicles using an 18-g needle attached to a 5 ml syringe (aspiration I) or using a constant negetive pressure (-80 mmHg) with a vacuum pump (aspiration II). The oocytes were classified into 4 classes on the basis of the morphology of cumulus cells and cytoplasmic appearance of oocyte. Slicing ($9.6{\pm}0.4$) and puncture ($9.7{\pm}0.4$)yielded a larger number of oocytes per ovary than other two aspiration methods (aspiration I and II were $5.8{\pm}0.3$and $5.6{\pm}0.4$, respectively) (p<0.05). The number of the highest quality oocytes (grade A) per ovary was significantly higher in slicing ($4.2{\pm}0.2$) and puncture ($4.6{\pm}0.1$) methods than in other methods (aspiration I and II were $1.2{\pm}0.2$ and $1.4{\pm}0.2$, respectively) (p<0.05). The rate of nuclear maturation of the highest and higher quality oocytes (grade A and grade B, respectively) was not affected by the oocytes collection methods. The oocytes collection methods also did not influence subsequent embryonic developmental competence after in vitro fertilization with M II stage oocytes. It is concluded that slicing and puncture methods of the ovaries can be used as an alternative techniques to aspiration by the syringe or vacuum pump.

A Study on the Design and Development of Interactive Non-Face-to-Face Real-Time Classes using EduTech : A Case Study of Christian Education Class (에듀테크를 활용한 상호작용적 비대면 실시간 수업 설계 및 개발 연구 : 기독교교육과 수업 사례를 중심으로)

  • Nam, Sunwoo
    • Journal of Christian Education in Korea
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    • v.66
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    • pp.343-382
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    • 2021
  • This study is a case study in which the interactive non-face-to-face classes using Edutech were applied to the Department of Christian Education. The subjects were 20 students from the Christian education department of A University located in the metropolitan area. The course was 'Instructional Methods and Educational Technology' in the first semester of 2020. In theory, I studied non-face-to-face classes and interaction, and edutech and interaction. Afterward, it designed and developed interactive non-face-to-face classes using edutech. The interactive non-face-to-face classes using edutech were developed as a process of applying Flipped-PBL based interactive edutech. In addition, Edutech was selected for active interaction according to the Flipped-PBL process to be carried out in a non-face-to-face situation. In particular, in the process of developing the problem of PBL, it was built around the situation of the church. As a result of applying the class, first, learners showed high satisfaction and interest in the class. Second, positive transference appeared in the space of learning and the space of living. Third, interactive non-face-to-face classes using Edutech have generated active interaction. In particular, interactive edutech and learning methods have become the main factors enabling active interaction. Through this, learners have improved learning efficiency, immersion, and satisfaction. Also, as an alternative to face-to-face classes, I was able to experience online classes. In other words, the satisfaction and interest of learning, and the transference of learning space, were also possible through active interactions generated through learning methods using interactive Edutech used in class. Furthermore, disabilities in the online communication(Internet) environment and learners' unfamiliarity with the online environment have been found as factors that hinder learning satisfaction and interaction. During learning, obstacles to the online communication environment hinder the utilization of interactive Edutech, preventing active interactions from occurring. This results in diminishing satisfaction and interest in learning. Therefore, we find that designing interactive non-face-to-face classes using Edutech requires sufficient learner learning and checking of the online communication(Internet) environment in advance for Edutech and learning methods. In response, this study confirmed the possibility by applying interactive non-face-to-face classes using Edutech to Christian education classes as an alternative method of education that allows active interaction and consistent transference of learning and life. Although it is a case study with limited duration and limitations of the number of people, I would like to present the possibility as an alternative Christian education method of an era where the direction of online classes should be presented as an alternative to a face-to-face class.