• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제41회 하계 정기 학술대회 초록집
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• pp.73-73
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• 2011

We will report a few methods to improve the efficiency and stability in small molecule based organic solar cells, including the formation of bulk heterojunctions (BHJs) through alternative thermal deposition (ATD), the use of a micro-cavity structure and interface modifications. By ATD which is a simple modification of conventional thermal evaporation, the thicknesses of alternative donor and acceptor layers were precisely controlled down to 0.1 nm, which is critical to form BHJs. The formation of a BHJ in copper(II) phthalocyanine (CuPc) and fullerene (C60) systems was confirmed by AFM, GISAXS and absorption measurements. From analysis of the data, we found that the CuPc|C60 films fabricated by ATD were composed of the nanometer sized disk shaped CuPc nano grains and aggregated C60, which explains the phase separation of CuPc and C60. On the other hand, the co-deposited CuPc:C60 films did not show the existence of separated CuPc nano grains in the CuPc:C60 matrix. The OPV cells fabricated using the ATD method showed significantly enhanced power conversion efficiency compared to the co-deposited OPV cells under a same composition [1]. We will also present by numerical simulation that adoption of microcavity structure in the planar heterojunction can improve the short circuit current in single and tandem OSCs [2]. Interface modifications also allowed us to achieve high efficiency and high stability OSCs.

• 대한한의학회지
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• 제38권3호
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• pp.13-29
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• 2017

Objectives: The objective of this review is to investigate the use of conventional Western medicine (WM) and complementary and alternative medicine (CAM) on leg cramps. Leg cramps are the occurrence of muscular spasm in the leg muscles which occur frequently in the elderly and are frequently observed in the clinical field. Methods: Relevant clinical studies were searched from five medical databases including PubMed, KISS, RISS, OASIS, and J-STAGE. Systematic review, clinical studies, and clinical practice guideline were included in this review. Results: In total, 27 clinical studies, 9 systematic review and meta-analysis, and 1 clinical practice guideline met the inclusion criteria. Included studies were classified and analyzed according to the type of intervention. Studies on quinine and magnesium have been most studied in WM and CAM, respectively. Although quinine shows some clinical effects on leg cramps, however, the risk of side effects are suggested. In addition, magnesium failed to improve the clinically significant effects in most studies. Five case reports using Oriental herbal medicine (OHM) were included and OHMs were effective in improving leg cramps without side effects, however, the quality of evidence was low. Clinical studies on other interventions were lacking. Conclusions: The results of this study indicate that there is no definite treatment standard for leg cramps until now, and there are limitations such as low level of evidence and side effects for each treatment. OHM can be an effective alternative to conventional intervention on leg cramps, therefore, related clinical studies are needed.

• 한국해양공학회지
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• 제19권5호
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• pp.16-25
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• 2005

The effect of vertical riser support system on the dynamic behaviour of a classical spar platform is investigated. Spar platform generally uses buoyancy-can riser support system, but as water depth gets deeper the alternative riser support system is required due to safety and cost issues. The alternative riser support system is to hang risers off the spar platform using pneumatic cylinders rather than the buoyancy-can. The existing numerical model for hull/mooring/riser coupled dynamics analysis treats riser as an elastic rod truncated at the keel (truncated riser model), thus, in this model, the effect of riser support system can not be modeled correctly. Due to this reason, the truncated riser model tends to overestimate the spar pitch and heave motion. To evaluate more realistic global spar motion, mechanical coupling among risers, guide frames and support cylinders inside of spar moon-pool should be modeled. In the newly developed model, the risers are extended through the moon-pool by using nonlinear finite element methods with realistic boundary condition at multiple guide frames. In the simulation, the vertical tension from pneumatic cylinders is modeled by using ideal-gas equation and the vertical tension from buoyancy-cans is modeled as constant top tension. The different dynamic characteristics between buoyancy-can riser support system and pneumatic riser support system are extensively studied. The alternative riser support system tends to increase spar heave motion and needs damper system to reduce the spar heave motion.

• Journal of Animal Science and Technology
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• 제63권3호
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• pp.465-474
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• 2021

It has become important to explore alternative feed ingredients to reduce feed costs, which are burdensome for livestock production. In addition, it is desirable to find efficient and functional alternative ingredients for traditional feed ingredients in pig diets, considering the stress and sensitivity of disease of pig. Rice is produced around the world like corn that is the typical energy source in pig diets. Although the nutritional quality varies depending on the degree of milling, rice, except whole grains (paddy rice), contains more starch than corn and its structure and granule size are easier to digest than corn. In addition, the fact that rice has fewer non-starch polysaccharides (NSP) and anti-nutritional factors (ANFs) is also effective in improving digestibility and various polyphenols in rice can help modulation of immune responses, which can be beneficial to the gastrointestinal environment and health of pig. Many studies have been conducted on rice focusing on things such as degree of milling, substitution rates of corn, granule size, and processing methods. Most results have shown that rice can be partially or completely used to replace corn in pig diets without negatively affecting pig growth and production. While further research should focus on the precise biological mechanisms at play, it was confirmed that the use of rice could reduce the use of antibiotics and pig removal and protect pigs from gastrointestinal diseases including diarrhea. From this point of view, rice can be evaluated as a valuable feed ingredient for swine diets.

• 대한치과교정학회지
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• 제51권5호
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• pp.346-354
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• 2021

Objective: To compare the effectiveness of ibuprofen, acetaminophen, and chewing gum for orthodontic pain relief and to assess if chewing gum can be a non-pharmacological alternative for orthodontic pain relief. Methods: The study enrolled 106 patients of both sexes, aged ≥ 12 years, with body weight > 50 kg, and mild-to-moderate dental crowding in the upper arch. After randomization and allocation concealment, the intervention groups were either administered with ibuprofen (400 mg) or acetaminophen (500 mg) or chewed sugar-free chewing gum immediately after initial archwire placement and every 6 hours for 1 week if the pain persisted. The control group did not receive any pain relief. The pain was assessed on a 100-mm visual analog scale at rest and while biting down at T1 (2 hours), T2 (24 hours), T3 (2 days), T4 (3 days), T5 (7 days), and T6 (21 days). Statistical analyses were performed using the Kruskal-Wallis and post-hoc Mann-Whitney U tests (α = 0.05). Results: The chewing gum group experienced more pain relief than the ibuprofen group at while biting down at T3 (p = 0.04) and at rest at T4 (p < 0.001). The chewing gum group reported more pain relief than the acetaminophen and control groups while biting down at T3 (p = 0.03 and p = 0.0006, respectively) and T4 (both p < 0.001). Conclusions: Chewing gum can be a non-pharmacological alternative for orthodontic pain relief at 2 and 3 days after initial archwire placement.

• 한국안전학회지
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• 제34권3호
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• pp.96-101
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• 2019

Chemicals Control Act have been strengthened to control more safely hazardous chemicals from 2015. In particular, the standards for the installation and management of handling facilities was enhanced with specific regulations depending on type of the facilities and the hazardous chemicals. However, some standards for handling facilities caused difficulties in implementing the strengthened standards due to various field conditions, such as lack of physical space. The Ministry of Environment is implementing Safety Assessment System (SAS) to solve these problems since 2018. However, many plants have difficulties in preparing alternative methods to pass the safety evaluation. The purpose of this study was to review and analyze the SAS and to suggest alternative measures in terms of management and technical aspects through the case study of hydrochloric acid storage tanks. The following safety solutions were suggested for handling facilities that had insufficient the space and capacity for the retaining wall due to physical space. Firstly, insufficient space was resolved by introducing equipment relocation or demolition, and retaining wall expansion. Secondly, the wall of the surrounding buildings was used as an alternative to the retaining wall with additional chemical resistant treatment. Finally, sensor installation and facility inspection were suggested as ways to improve chemical safety. Therefore, improvement of chemical accident prevention system is required not only in terms of facilities supplementation but also management aspect. The results of this study are expected to be available for similar facilities and will be based on the preparation of additional safety assessment as alternatives measures in the future.

• 한방비만학회지
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• 제18권2호
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• pp.83-95
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• 2018

Objectives: The aim of this study was optimized mixing ratio of mulberry leaf, mulberry fruit, and silkworm for amelioration of the metabolic syndrome by using response surface method (RSM). Methods: Antioxidant, antidiabetic and antihypertensive activities of fifteen mixed powder of mulberry leaf, mulberry fruit, and silkworm by RSM were measured as indicators of metabolic syndrome. Results: The optimal mixing ratio of mulberry leaves, mulberry fruits, and silkworm with the greatest antioxidant, antidiabetic and antihypertensive activities was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C). At this time, it was predicted that the total polyphenol content was estimated to be 185.51 tannic acid equivalent mg/g, 1, 1-diphenyl-2-picrylhy drazyl radical scavenging activity 84.77%, 1-deoxynojirimycin content 415.66 mg/100 g, ${\alpha}-glucosidase$ inhibitory activity 64.31%, ${\gamma}-aminobutyric$ acid content 267.77 mg/100 g, potassium content 1,899.11 mg/100 g, and angiotensin-converting-enzyme inhibitory activity was estimated to be 73.78%. Conclusions: It was concluded that the significant effect of the mulberry leaf, mulberry fruit, and silkworm on the metabolic syndrome-related biological activity indices (antioxidant activity, antidiabetic activity and antihypertensive activity) was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C).

• 융합보안논문지
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• 제20권4호
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• pp.3-12
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• 2020

국방 무기체계 연구개발 과정에서 관련 규정이나 지침에 명시되지 않았지만, 연구개발 주관기관 내부적으로도 합리적인 대안 선택의 문제가 많이 발생한다. 대안 선택에 있어서 합리적인 과정이 적용되지 않으면 사업진행에 차질을 초래할 수 있으며, 이로 인해 사업기간 연장이나 추가 자원이 투입되는 상황도 발생된다. 특히 국내 미사일 연구개발 시 시험평가를 위한 많은 의사결정 과제들이 도출되며, 대표적인 것 중의 하나가 시험장 선정의 문제이다. 대안이 되는 시험장의 우선순위만 판단해야 한다면 델파이 기법(Delphi Method)이나 분석적계층과정(Analytic Hirarchy Process)을 활용할 수 있지만, 비용의 투입요소가 고려된다면 자료포락분석(Data Envelopment Analysis) 더 적합하다. 본 연구에서는 미사일 시험 시 발생되는 다양한 의사결정의 문제들을 염출해 보고, 이를 합리적으로 해결할 수 있는 의사결정의 방법이 제시된다. 제시된 의사결정의 프레임워크(Framework)는 국외 시험장을 선정하는 문제와 연관하여 모의 사례연구(Simulated Case Study)로 적용 과정이 연구된다.

• 동의신경정신과학회지
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• 제33권4호
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• pp.401-424
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• 2022

Objectives: As effective treatments for dementia are lacking in Western medicine, complementary and alternative medicine (CAM) is considered a useful option. While the quality of life (QoL) is a vital outcome for patients with dementia, the QoL of patients receiving CAM for dementia remains ambiguous. This study aimed to determine the effect of CAM on QoL outcomes in dementia patients. Methods: A search was performed using the keywords "dementia," "Alzheimer's," "cognitive impairment," "Chinese," "Korean," "oriental," "herbal," "acupuncture," and "quality of life". All quantitative data were synthesized using R version 4.1.1. Results: Twenty-five randomized controlled trials (RCTs), 16 pre-post trials, and two cohort studies were selected for the systematic review. QoL in Alzheimer's disease (QOL-AD) (n=11, 25.6%) and geriatric QoL in dementia (GQOL-D, n=9, 20.9%) were the most utilized QoL instruments. Significant benefits in QoL were observed after receiving mind, body, combined mind and body, nursing, oriental medicine, and acupuncture therapies. In the meta-analysis, the combined effect was shown to significantly increase QOL-AD compared to before CAM interventions (standardized mean difference, SMD: 0.507; 95% confidence interval (CI), 0.191~0.824; p<0.01). The overall synthesized estimates in the GQOL-D showed a significantly improved QoL (SMD: 0.537, 95% CI: 0.238~0.837 p<0.01; one group; SMD: 1.465, 95% CI: 0.934~1.996, p<0.01). The seven studies assessing the cost-effectiveness of CAM reported uncertain outcomes. Conclusions: This study showed that CAM interventions benefited patients with dementia by improving their QoL. While additional standardized research is required, CAMs are suggested as effective clinical management for patients with dementia. They are also suggested as complementing therapies for these patients.

• Animal Bioscience
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• 제36권7호
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• pp.1059-1066
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• 2023

Objective: Present study was designed to evaluate the efficacy of Acacia nilotica bark extract as an alternative to antibiotic growth promoters in broilers. Methods: Six hundred, day-old broiler chicks were randomly divided into six groups (NC, without any supplementation; AB, NC+Zinc Bacitracin; PB, NC+Safmannan; ANBE1, NC+A. nilotica bark extract 0.1%; ANBE3, NC+A. nilotica bark extract 0.3%; ANBE5, NC+A. nilotica bark extract 0.5%), with ten replicates per group (10 chicks/replicate) and feeding trial was lasted for 35 days. Results: Results showed that weight gain (1,296.63 g) and feed conversion ratio (FCR, 1.59) of AB was better than NC, during the finisher phase. Overall FCR of AB (1.53), PB (1.54), and ANBE5 (1.54) was significantly (p<0.05) better than NC. From carcass parameters relative weight of wing and heart were highest in ANBE3 (2.5% and 1.51%, respectively). Significantly (p<0.05) highest blood glucose level was observed in NC (264.5 mg/dL) and highest albumin concentration was found in AB (1.46 mg/dL). In addition, antibody titer levels against ND and IBD were higher in ANBE5 than NC, while higher relative weight of bursa was observed in ANBE3 than NC. The villus height to crypt depth ratio in all experimental groups was better than NC. Conclusion: Acacia nilotica bark extract could be a suitable alternative to antibiotic growth promoters to support the growth in broilers.