• Title/Summary/Keyword: Alternative methods

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A Preliminary Study for Effect of High Flow Oxygen through Nasal Cannula Therapy in Carbon Monoxide Poisoning (일산화탄소 중독 환자에서 고유속 비강 캐뉼라 산소치료 효과에 대한 예비 연구)

  • Kim, Young-Min;Kim, Sang-Chul;Park, Kwan-Jin;Lee, Seok-Woo;Lee, Ji-Han;Kim, Hoon
    • Journal of The Korean Society of Clinical Toxicology
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    • v.17 no.2
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    • pp.102-107
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    • 2019
  • Purpose: Acute carbon monoxide (CO) poisoning is one of the most common types of poisoning and a major health problem worldwide. Treatment options are limited to normobaric oxygen therapy, administered using a non-rebreather face mask or hyperbaric oxygen. Compared to conventional oxygen therapy, high-flow nasal cannula oxygen (HFNC) creates a positive pressure effect through high-flow rates. The purpose of this human pilot study is to determine the effects of HFNC on the rate of CO clearance from the blood, in patients with mild to moderate CO poisoning. Methods: CO-poisoned patients were administered 100% oxygen from HFNC (flow of 60 L/min). The fraction of COHb (fCOHb) was measured at 30-min intervals until it decreased to under 10%, and the half-life time of fCOHb (fCOHb t1/2) was subsequently determined. Results: At the time of ED arrival, a total of 10 patients had fCOHb levels ≥10%, with 4 patients ranging between 10% and 50%. The mean rate of fCOHb elimination patterns exhibits logarithmic growth curves that initially increase quickly with time (HFNC equation, Y=0.3388*X+11.67). The mean fCOHbt1/2 in the HFNC group was determined to be 48.5±12.4 minutes. Conclusion: In patients with mild to moderate CO poisoning, oxygen delivered via high flow nasal cannula is a safe and comfortable method to treat acute CO toxicity, and is effective in reducing the COHb half-life. Our results indicate HFNC to be a promising alternative method of delivering oxygen for CO toxicity. Validating the effectiveness of this method will require larger studies with clinical outcomes.

A Retrospective Study of Autism Spectrum Disorder in Children Treated by Korean Medicine (한의학적 치료를 받은 자폐 스펙트럼 장애 환아 63례에 대한 후향적 차트리뷰)

  • Park, So Hyun;Kim, Ye Ji;Park, Sul Gi;Lee, Sun Haeng;Lee, Jihong;Park, Yong Seok;Kim, Jae Hyun;Chang, Gyu Tae;Lee, Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.3
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    • pp.43-52
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    • 2021
  • Objectives This study aimed to analyze the clinical characteristics of 63 patients with autism spectrum disorder (ASD) who received Korean medicine treatment. Methods This study identified and retrospectively reviewed the first visit records and clinical characteristics of all of the patients who visited the Kyung Hee University Korean Medicine Hospital and Kyung Hee University Korean Medicine Hospital at Gangdong in South Korea with ASD as their chief complaints. The herbal medicines that were prescribed according to the patient's symptoms were analyzed by separating them into categories. Results The data of 83 children with ASD were collected. Among them, the primary medical record charts of 63 patients were reviewed. Additional analysis was performed for 56 patients who were treated with herbal medicine. Through a retrospective chart review, the patients' clinical characteristics and the tendency of the prescribed herbal medicine was identified. Conclusions This study was conducted to provide preliminary data that proposes Korean medicine as a new alternative medical treatment. Our study is meaningful as it used the demographic and clinical records of 63 patients with ASD in Korea who visited an Korean medicine hospital in the last 11 years to identify tendencies and analyzed the prescriptions of two or more Korean medicine pediatricians.

Comparison of Labor Period, Work Time, and Seedling Growth in Cutting and Pinning Transplants on 'Maehyang' Strawberry ('매향' 딸기 삽목묘와 유인묘의 노동 기간, 작업 시간 및 생육 비교)

  • Hwang, Hee Sung;Jeong, Hyeon Woo;Kang, Jae Hyeon;Hwang, Seung Jae
    • Journal of Bio-Environment Control
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    • v.30 no.4
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    • pp.257-262
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    • 2021
  • The pinning method is the traditional method to produce strawberry transplants. But, cultivating the pinning transplant is a labor-intensive operation and needs a long labor period. The cutting method has been considered as an effective alternative to the pinning method, due to the relatively short labor period and works time. This study was conducted to investigate the labor period, work time, and growth between pinning and cutting methods for strawberry transplants. The 'Maehyang' strawberry was cultivated at each pinning and cutting strawberry greenhouses. The time for special works on pinning method (pinning work, elimination of mother plant, and division of daughter plant), and cutting method (cutting collection, pretreatment before storage, and cutting work) were measured. The pinning method needed 6 tasks (planting of mother plant, maintaining of mother plant, pinning work, maintaining of daughter plant, elimination of mother plant, and division of daughter plant) for 158 days, and cutting method needed 4 tasks (collection and storage of cutting, cutting work, misting, and maintaining of transplants) for 113 days to cultivate transplants for fruit. And pinning method needed more work time than the cutting method. There was no significant difference between the growth of pinning and cutting transplants. These results showed that the cutting method saved more labor period, work time than pinning during the nursery period without losing transplant quality.

Investigation on the Key Parameters for the Strengthening Behavior of Biopolymer-based Soil Treatment (BPST) Technology (바이오폴리머-흙 처리(BPST) 기술의 강도 발현 거동에 대한 주요 영향인자 분석에 관한 연구)

  • Lee, Hae-Jin;Cho, Gye-Chum;Chang, Ilhan
    • Land and Housing Review
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    • v.12 no.3
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    • pp.109-119
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    • 2021
  • Global warming caused by greenhouse gas emissions has rapidly increased abnormal climate events and geotechnical engineering hazards in terms of their size and frequency accordingly. Biopolymer-based soil treatment (BPST) in geotechnical engineering has been implemented in recent years as an alternative to reducing carbon footprint. Furthermore, thermo-gelating biopolymers, including agar gum, gellan gum, and xanthan gum, are known to strengthen soils noticeably. However, an explicitly detailed evaluation of the correlation between the factors, that have a significant influence on the strengthening behavior of BPST, has not been explored yet. In this study, machine learning regression analysis was performed using the UCS (unconfined compressive strength) data for BPST tested in the laboratory to evaluate the factors influencing the strengthening behavior of gellan gum-treated soil mixtures. General linear regression, Ridge, and Lasso were used as linear regression methods; the key factors influencing the behavior of BPST were determined by RMSE (root mean squared error) and regression coefficient values. The results of the analysis showed that the concentration of biopolymer and the content of clay have the most significant influence on the strength of BPST.

Recent Research Trends of Cryopreservation Technology Based on Microalgae Chlorophyta (미세조류 동결보존 기술 개발의 최근 연구 동향)

  • Yim, Jun-Ho;Seo, Yong Bae;Kim, Seon Min;Jeon, Young Jae
    • Journal of Life Science
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    • v.31 no.10
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    • pp.960-968
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    • 2021
  • Since microalgae research started on late 18 century, they have been recognized as one of the most important bioresources used in bioindustry. Owing to the large efforts paid to industrial application of this microorganisms, their importance on food/feed and bioactive compounds has been further extending into the environmental research areas including alternative energy resources, mitigation of the carbon emission, and waste-water treatment. However, despite the importance on their industrial application, the fundamental research field related to the long-term preservation of microalgae culture has not received much attention. However, a less labor intensive and cost-efficient preservation technology enabling biologically active and stable microalgae-culture provides a key success factor in the biotechnological application. Therefore, this study investigated various cutting-edge microalgae cryopreservation technologies currently developed so far, mainly targeting Chlorophyta, which occupies the largest taxon in the classification system of microalgae. In addition, for the development of successful cryopreservation technique, the key factors such as temperature control effect and preservative effect during cryopreservation of microalgae culture were investigated. In addition, the problems with current preservation technology that is being used in Korean domestic biological resource banks and the international microalgal resource banks are described. According to our investigation, currently no standard method for long-term preservation of microalgae is available due to their various morphological and physiological characteristics. To overcome such issues, much more efforts on fundamental research area on the identification of specific biomarker used for microalgae taxonomical classification and further systemic approaches based on strain-specific cryopreservation methods needed.

Method development for efficacy testing of veterinary disinfectants using bacteriophage MS2 (Bacteriophage MS2를 이용한 소독제 효력시험 확립에 관한 연구)

  • Rhee, Chae Hong;Kim, Soohee;Han, Bokhee;Kim, Young-Wook;Her, Moon;Jeong, Wooseog
    • Korean Journal of Veterinary Service
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    • v.44 no.3
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    • pp.149-155
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    • 2021
  • In virucidal efficacy testing, the chemical inactivation cannot be determined for all viruses due to the difficulties or the inability to culture sufficiently or the risk of exposure to the viruses. Therefore, disinfectants against these viruses could be evaluated by different methods and surrogate viruses are used as alternative. In this study we developed a method for efficacy testing of veterinary disinfectants using one of the candidate surrogate viruses, bacteriophage MS2, as part of the research on the selection of surrogate viruses for efficiency of efficacy testing of veterinary disinfectants. This method is based on the Animal and Plant Quarantine Agency (APQA) guidelines for efficacy testing of veterinary disinfectants. Bacteriophage and disinfectant are reacted in suspension in accordance with the APQA guidelines and then a newly established double agar layer method is applied for the efficacy test. The double agar layer method is summarized as follows: 1) The bottom agar with 1.5% agar is boiled and cooled before poured into petri dishes at volume of 20 mL, and dried under biological safety cabinet. 2) The top agar with 0.7% agar is boiled and kept at 50℃ before E. coli culture was seeded. 3) The serially diluted bacteriophage MS2-disinfectant mixtures 0.05 mL and E. coli host 0.01 mL (OD600 0.2~0.3) are mixed with 5 mL of top agar and incubate them at 50℃ for 5 min for reaction. 4) The resulting mixture is poured over top of a bottom agar plate and rocked sufficiently to ensure that the top agar covers the entire surface of the bottom agar. 5) The double agar layer is then placed under biological safety cabinet to allow the agar layer to solidify and subsequently incubated at 37℃ for 24 hr. 6) Following incubation, the plates may be inspected for plaques and record results.

A Rating Method for the Estimation of the Additional Overhead Expenses incurred by Schedule Extension in Public Construction Projects (공공건설공사의 공기연장에 따른 추가간접비 산출을 위한 요율방식 제안)

  • Lee, Seung-Joon;Cha, Yongwoon;Han, Sangwon;Hyun, Chang-Taek
    • Korean Journal of Construction Engineering and Management
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    • v.22 no.3
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    • pp.79-90
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    • 2021
  • In domestic public construction, disputes are increasing due to differences among stakeholders regarding contract price adjustment. In particular, the actual cost-plus fee for overhead costs due to the schedule extension cannot be agreed upon at the administrative phase, and most of them seek judicial judgment. Thus, this study aims to propose a 'sufficiently satisfactory' alternative to reach an agreement before disputes in order to minimize disputes related to the calculation of additional overhead costs. To this end, this study proposes three alternatives based on the rate method. Firstly, when calculating additional overhead costs, it is not calculated as an actual cost-plus-fee method, but as a rate compared to direct labor costs among net direct costs. Secondly, the calculated indirect labor costs are compensated for up to the legal maximum of legal limit costs such as general management costs, profits and so on. Thirdly, it reflects overhead costs increased or decreased due to change orders. Risks were analyzed by collecting expert opinions on the proposed methods and applying actual cases. Finally, as a result of investigating the level of consensus for each stakeholder, it was confirmed that all stakeholders could agree regardless of the size of the company. The result of this study is expected to as a useful tool among stakeholders in the construction fields that can be able to easily agreed upon.

The Multi-Scalar Practices of the Labour and Economic Geography of TNCs: A Study on the Labour Geography of Nestlé Korea (노동자들의 다중스케일적 실천과 초국적 기업의 경제지리: 한국네슬레노동조합의 노동지리를 사례로)

  • Hwang, Jin-Tae
    • Journal of the Economic Geographical Society of Korea
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    • v.24 no.1
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    • pp.52-75
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    • 2021
  • The current Korean labour movement is at an impasse that is partly sustained by the idea of "strong" transnational corporations (TNCs) versus "weak" labour, and this perception is based on the "global-local dichotomy," wherein TNCs are depicted as abstract and structured entities operating at the global scale and workers are represented as having a concrete and weak presence within the local sphere. As an alternative perspective to break this "global" capital vs. "local" labour dichotomy, I focus on labour geography, which assumes that labour is not simply a factor of production but a sentient spatial actor that (un-)intentionally produces the landscape of capitalism. Borrowing insights from the multi-scalar perspective, this paper aims to understand the actual methods in which workers utilize spatial strategies through an empirical case study of the Nestlé Korea labour union strike in 2003. Based on this case study, this paper claims that workers are both capable of employing coordinated multi-scalar practices and can be more influential to the economic geographies of TNCs. Additionally, it suggests that workers' scalar practices are actually more complicated and multi-directional as a result of their complex and dynamic interactions with political, economic and cultural forces and actors at diverse geographical scales.

Configuration of Fuel Cell Power Generation System through Power Conversion Device Design (전력변환장치 설계를 통한 연료전지 발전시스템 구성)

  • Yoon, Yongho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.21 no.6
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    • pp.129-134
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    • 2021
  • Recently, the demand for electricity is gradually increasing due to the rapid industrial development and the improvement of living standards. In the case of Korea, which is highly dependent on fossil fuels due to such a surge in electricity demand, reduction and freezing of greenhouse gas emissions due to international environmental regulations will immediately lead to a contraction in industrial activities. Accordingly, there are many difficulties in competition with advanced countries that want to link the environment with the country's industrial production activities, and the development of alternative energy as a countermeasure is of great interest around the world. Among these new power generation methods, small-scale power generation facilities with relatively small capacity include photovoltaic generation, wind power generation, and fuel cell generation. Among them, the fuel cell attracts the most attention in consideration of continuous operation, high power generation efficiency, and long-term durability, which are important factors for practical use. Therefore, in this paper, the fuel cell power generation system was researched and constructed by designing the power conversion circuit necessary to finally obtain the AC power used in our daily life by using the DC power generated from the fuel cell as an input.

GEO-KOMPSAT-2A AMI Best Detector Select Map Evaluation and Update (천리안위성2A호 기상탑재체 Best Detector Select 맵 평가 및 업데이트)

  • Jin, Kyoungwook;Lee, Sang-Cherl;Lee, Jung-Hyun
    • Korean Journal of Remote Sensing
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    • v.37 no.2
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    • pp.359-365
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    • 2021
  • GEO-KOMPSAT-2A (GK2A) AMI (Advanced Meteorological Imager) Best Detector Select (BDS) map is pre-determined and uploaded before the satellite launch. After the launch, there is some possibility of a detector performance change driven by an abrupt temperature variation and thus the status of BDS map needs to be evaluated and updated if necessary. To investigate performance of entire elements of the detectors, AMI BDS analyses were conducted based on a technical note provided from the AMI vendor (L3HARRIS). The concept of the BDS analysis is to investigate the stability of signals from detectors while they are staring at targets (deep space and internal calibration target). For this purpose, Long Time Series (LTS) and Output Voltage vs. Bias Voltage (V-V) methods are used. The LTS for 30 secs and the V-V for two secs are spanned respectively for looking at the targets to compute noise components of detectors. To get the necessary data sets, these activities were conducted during the In-Orbit Test (IOT) period since a normal operation of AMI is stopped and special mission plans are commanded. With collected data sets during the GK2A IOT, AMI BDS map was intensively examined. It was found that about 1% of entire detector elements, which were evaluated at the ground test, showed characteristic changes and those degraded elements are replaced by alternative best ones. The stripping effects on AMI raw images due to the BDS problem were clearly removed when the new BDS map was applied.