• 한국동물생명공학회지
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• 제34권2호
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• pp.86-92
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• 2019

The aim of this study was to investigate effects of hyaluronidase during IVM on oocyte maturation, oxidative stress status, expression of cumulus expansion-related (PTX, pentraxin; GJA1, gap junction protein alpha 1; PTGS2, prostaglandin-endoperoxide synthase 2) and fatty acid metabolism-related (FADS1, delta-6 desaturase; FADS2, delta-5 desaturase; PPARα, peroxisome proliferator-activated receptor-alpha) mRNA, and embryonic development of porcine oocytes. The cumulus-oocyte complexes (COCs) were incubated with 0.1 mg/mL hyaluronidase for 44 h. Cumulus expansion was measured at 22 h after maturation. At 44 h after maturation, nuclear maturation, intracellular glutathione (GSH) and reactive oxygen species (ROS) levels were measured. Gene expression in cumulus cells was analyzed using real time PCR. The cleavage rate and blastocyst formation were evaluated at Day 2 and 7 after insemination. In results, expansion of cumulus cells was suppressed by treatment of hyaluronidase at 22 h after maturation. Intracellular GSH level was reduced by hyaluronidase treatment (p < 0.05). On the other hand, hyaluronidase increased ROS levels in oocytes (p < 0.05). Only PTGS2 mRNA was enhanced in COCs by hyaluronidase (p < 0.05). Population of oocytes reached at metaphase II stage was higher in control group than hyaluronidase treated group (p < 0.05). Both of cleavage rate and blastocyst formation were higher in control group than hyaluronidase group (p < 0.05). Our present results showed that developmental competence of porcine oocytes could be reduce by hyaluronidase via inducing oxidative stress during maturation process and it might be associated with prostaglandin synthesis. Therefore, we suggest that suppression of cumulus expansion of COCs could induce oxidative stress and decrease nuclear maturation via reduction of GSH synthesis and it caused to decrease developmental competence of mammalian oocytes.

• Journal of international Conference on Electrical Machines and Systems
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• 제3권4호
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• pp.458-464
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• 2014

This paper proposes the rotor position and rotor speed estimation for an interior permanent magnet synchronous machines (IPMSM) using Unscented Kalman Filter (UKF) in alpha-beta coordinate system. Conventional algorithms using UKF are based on the simple observer model of IPMSM in d-q coordinate system. Rotor acceleration is neglected within the sampling step. An expansion of the observer model in an alpha-beta coordinate system with the consideration of the rotor speed variation provides the improved rotor position and speed estimation. The results show good stability concerning the expansion of observer model for the IPMSM.

• 한국세라믹학회지
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• 제25권5호
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• pp.431-436
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• 1988

The properties of scid-resistance to boiling HCl, thermal expansion coefficient and softening temperature of mother glass and glass-ceramic of LAS systems were investigated at the contents of SiO2 varing from 57 to 67wt%. The nucleation and growth of crystalline phase of LAS compositions were carried out at 50$0^{\circ}C$ and $700^{\circ}C$. The crystalline phase jconsists of lithium alumino silicate, lithum meta silicate, lithium disilicate, $\alpha$-crystobalite and $\alpha$-quartz. Lithium alumino silicate(virgilite) is the major crystalline phase in the glass ceramics. The degree of acid resistant property was increased in proportion with the silica content for both glass and ceramics. Glass-ceramic gives lower acid-resistance and thermal expansion coefficient while softening temperature shows higher for glass-ceramic than for mother glass.

• 한국세라믹학회지
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• 제30권2호
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• pp.107-114
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• 1993

Zinc-Borosilicate(ZnO 65.0wt%, B2O3 21.5wt%, SiO2 9.0wt%, PbO or tiO2 4wt%) passivation glasses were studied using differential thermal analysis(DTA), scanning electron microscopy(SEM) observations, X-ray diffraction (XRD) patterns and measurement of thermal expansion coefficients. Passivation glasses containing 4wt% TiO2 and 4wt% PbO had crystallization temperature of 680~73$0^{\circ}C$ and major crystalline phases were identified by X-ray diffraction as $\alpha$-ZnO.B2O3 and $\alpha$-5ZnO.2B2O3. As increasing firing temperature, the size of crystalline phases increased by observation of SEM. The thermal expansion coefficient of crystallized glass frits was smaller than that of unfired glass.

• 한국안전학회지
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• 제13권4호
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• pp.142-154
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• 1998

A stirling engine is a mechanism used to convert heat to power and operates on a closed regenerative thermodynamic cycle with compression and expansion of the working fluid at different temperature. The performance of a stilting cycle machine is a function of six independent parameters, namely; (1) speed N(r.p.m), (2) pressure of the working fluid p(Pa), (3) ratio of the temperature in the compression and expansion space ${\tau}(=T_C/T_E)$ , (4) ratio of the swept volumes in these two spaces K, (5) phase angle $\alpha$ and (6) dead volume ratio X. This paper describes the procedure and presents the results of computations carried out to establish the optimum combinations of these six parameters for maximum engine output for the machine acting as a prime mover, over a combined temperature range from $300^{\circ}K$ to $1000^{\circ}K$ and dead volume ratio X ranging from 0.1 to 2.0. The output of a stilting cycle machine can be expressed in terms of nondimensional power in several different ways. Four methods were studied in detail, the parameters optimized and design charts and engine power charts prepared. The results of this paper may be useful as a guide to the likely effects on the performance of some of the important design parameters and regenerator design.

• 폴리머
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• 제34권4호
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• pp.352-356
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• 2010

2개의 종횡비에 의해 특징지어진 3차원 타원체를 사용하여 PP복합체의 충전제 형태와 함량이 열팽창률에 미 치는 영향에 대해 Lee와 Paul에 의해 제안된 이론적인 값과 실험적인 결과값이 비교분석되었다. 충전제의 형태는 구형에 황산바륨을, 섬유형에는 유리섬유를, 판상형에는 운모를 사용하였다. 실험의 결과로서 구형을 갖는 황산바륨 은 종횡비가 1의 값을 갖고 이론과 같이 열팽창률이 감소하였다. 유리섬유의 경우 함량증가에 따라 종횡비는 42, 37, 25, 20으로 감소하였으며 종단방향에선 열팽창률이 감소하였지만 수직방향에서는 증가하였다. 운모의 경우 그 함량증가에 따라 모두 종단방향과 횡단방향에서 감소하고 수직방향에서 증가하였다. 종횡비의 값은 각각, $\rho_\alpha$=13.5, $\rho_\beta$=1.8이었다.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2005년도 추계학술발표대회 논문집
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• pp.95-98
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• 2005

This paper proposes the solutions predicting the coefficient of the thermal expansion changes of composites which include the fiber-like shaped ($a_1$ > ($a_2$ = ($a_3$) and the disk-like shaped (al = a2> a3) inclusions like two dimensional geometries, which has one aspect ratios, ${\alpha}$ = ($a_1$ /($a_3$). The analysis follows the procedure developed for elastic moduli by using the generalized approach of Eshelby’s equivalent tensor. The influences of the aspect ratios, on the effective coefficient of thermal expansion of composites containing aligned isotropic inclusions are examined. This model should be limited to analyze the composites with unidirectionally aligned inclusions and with complete binding to each other of both matrix and inclusions having homogeneous properties. The coefficient of thermal expansion of composites (${\theta}_{11}$,${\theta}_{22}$and ${\theta}_{33}$) are investigated. From material data of the composites with glass fiber in epoxy resin, the thermal expansions along the aspect ratio were obtained and similar to the Chow model. The longitudinal coefficients of thermal expansion ${\theta}_{11}$decrease, as the aspect ratios increase. However, the transverse coefficients of thermal expansion ${\theta}_{22}$increase or decrease, as the aspect ratios increase. And both of them decrease, as the concentration increases.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1370-1373
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• 2003

Specimens of Ti-10Ta-10Nb have been tested for Rockwall hardness after heating to either the $\alpha$+$\beta$ and $\beta$-phase field. And the specific heat and the dilatometer of Ti-10Ta-103Nb swaged have been measured. From the result, the $\beta$ transus of the alloy was determined to be 82$0^{\circ}C$. The hot deformation behavior of Ti-10Ta-10Nb with an $\alpha$+$\beta$ microstructure is modeled in the temperature 75$0^{\circ}C$ and strain rate range 0.001-10$^{-1}$

• 대한수학회지
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• 제43권3호
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• pp.579-591
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• 2006

In this paper we obtain a sufficient and necessary condition for an analytic function f on the unit ball B with Hadamard gaps, that is, for $f(z)\;=\;{\sum}^{\infty}_{k=1}\;P_{nk}(z)$ (the homogeneous polynomial expansion of f) satisfying $n_{k+1}/n_{k}{\ge}{\lambda}>1$ for all $k\;{\in}\;N$, to belong to the weighted Bergman space $$A^p_{\alpha}(B)\;=\;\{f{\mid}{\int}_{B}{\mid}f(z){\mid}^{p}(1-{\mid}z{\mid}^2)^{\alpha}dV(z) < {\infty},\;f{\in}H(B)\}$$. We find a growth estimate for the integral mean $$\({\int}_{{\partial}B}{\mid}f(r{\zeta}){\mid}^pd{\sigma}({\zeta})\)^{1/p}$$, and an estimate for the point evaluations in this class of functions. Similar results on the mixed norm space $H_{p,q,{\alpha}$(B) and weighted Bergman space on polydisc $A^p_{^{\to}_{\alpha}}(U^n)$ are also given.

• Clinical and Experimental Reproductive Medicine
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• 제42권2호
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• pp.72-76
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• 2015

$17{\alpha}$-hydroxylase and 17,20-lyase are enzymes encoded by the CYP17A1 gene and are required for the synthesis of sex steroids and cortisol. In $17{\alpha}$-hydroxylase deficiency, there are low blood levels of estrogens, androgens, and cortisol, and resultant compensatory increases in adrenocorticotrophic hormone that stimulate the production of 11-deoxycorticosterone and corticosterone. In turn, the excessive levels of mineralocorticoids lead to volume expansion and hypertension. Females with $17{\alpha}$-hydroxylase deficiency are characterized by primary amenorrhea and delayed puberty, with accompanying hypertension. Affected males usually have female external genitalia, a blind vagina, and intra-abdominal testes. The treatment of this disorder is centered on glucocorticoid and sex steroid replacement. In patients with $17{\alpha}$-hydroxylase deficiency who are being raised as females, estrogen should be supplemented, while genetically female patients with a uterus should also receive progesterone supplementation. Here, we report a case of a 21-year-old female with $17{\alpha}$-hydroxylase deficiency who had received inadequate treatment for a prolonged period of time. We also include a brief review of the recent literature on this disorder.