• Archives of Pharmacal Research
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• 제15권4호
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• pp.304-308
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• 1992

The alkylation of resorcinol with cyclic allylic alcohol in non-aqueous acid medium gives intermolecular Friedel-Craft compounds. The products are primary alkylation products. The likage always occurs between carbon 3 of cyclic allylic alcohol and the position 2, 4, 5 or 6 of the resorcinol.

• 대한화학회지
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• 제42권5호
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• pp.503-505
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• 1998

• Bulletin of the Korean Chemical Society
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• 제18권8호
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• pp.800-802
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• 1997

• Bulletin of the Korean Chemical Society
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• 제10권1호
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• pp.102-103
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• 1989

Four coordinated rhodium(Ⅰ) complexes, Rh($ClO_4$)(CO)$(PPh_3)_2$ and [$Rh(CO)(PPh_3)_3$]$ClO_4$(2) catalyze the iosmerization of allylic alcohols to the corresponding carbonyl compounds at room temperature under nitrogen. The isomerization is faster with 2 than with 1, which is understood in terms of relative ease of the last step of the catalytic cycle, the reductive elimination of enol. Relative rates of the isomerization with 1 and 2 for different allylic alcohols are also explained by the relative ease of the enol elimination step in part. The first step of the catalytic cycle, the complex formation of the allylic alcohol through the ${\pi}-system$ of the olefinic group of the allylic alcohol and the following step, formation of hydridoallyl complex also seem to affect the overall rate of the isomerization.

• Archives of Pharmacal Research
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• 제15권4호
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• pp.371-373
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• 1992

3, 4, 5, 6, -Tetrahydro-7-hydroxy-2-methyl-9-alkyl-2, 6-methano-2H-1-benzoxocins are readily prepared by baron trifluoride etherate-catalyzed cyclization of resorcinols with cyclic allylic alcohol.

• Bulletin of the Korean Chemical Society
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• 제28권11호
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• pp.2096-2098
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• 2007

• 문화기술의 융합
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• 제10권6호
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• pp.781-788
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• 2024

(C₄H₄N₂H)₂Cr₃O₁₀을 제조하여, 원소분석, IR, UV-Vis, 열무게-시차열분석, TG-DTA-TMA system 등으로 착물의 구조 및 특성을 확인하였다. 여라 가지 용매에서 (C₄H₄N₂H)₂Cr₃O₁₀을 이용한 벤질 알코올의 산화 과정을 실험한 결과, 용매들의 유전상수 값이 증가함에 따라 산화반응이 증가하였다. 또한 CH₂Cl₂ 용매 하에서 (C₄H₄N₂H)₂Cr₃O₁₀을 이용한 알코올들의 산화 과정을 실험한 결과, benzylic alcohol, allylic alcohol, saturated primary alcohol, secondary alcohol들을 알데히드 혹은 케톤(70% ~ 96%)으로 전환시키는 효율적인 산화제였다. CH₂Cl₂ 용매 하에서 (C₄H₄N₂H)₂Cr₃O₁₀을 알코올 혼합물들의 산화 과정을 측정한 결과, secondary alcohol의 존재하에서, benzylic alcohol, allylic alcohol, saturated primary alcohol을 선택적으로 산화(10% ~ 96%) 시켰다. 산(HCl) 촉매를 첨가 후, DMF 용매 하에서, (C₄H₄N₂H)₂Cr₃O₁₀은 벤질 알코올과 그 치환체들을 효율적으로 산화시켰다. Hammett 반응상수(ρ) 계산 결과 -0.70(303K)를 나타내었다. 본 연구에서 알코올의 산화반응은 속도결정단계에서 수소화 전이가 일어났다.

• Bulletin of the Korean Chemical Society
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• 제30권7호
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• pp.1531-1534
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• 2009

(2S,3R)-3-Hydroxy-2-(hydroxymethyl)-3,6-dihydro-2H-pyridine 8, an important precursor for the synthesis of polyhydroxylated piperidine azasugars, has been prepared from L-serine. Highly stereoselective nucleophilic addition to amino aldehyde 5 gave the corresponding allylic alcohol 6 which proceeded to give dihydro-2H-piridine 7a via a Grubbs II catalyzed RCM. Stereoselective H-bond directed epoxidation of allylic alcohol led to the oxiranyl alcohol 9 which was easily converted to L-deoxyaltronojirimycin by regioselective ring opening.

• Archives of Pharmacal Research
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• 제10권4호
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• pp.239-244
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• 1987

An efficient and inexpensive method for the substitution of allylic hydroxyl group with fluoride, without allylic rearrangement, and elimination was developed. This method consists of treating an allylic alcohol with methylithium, followed by p-toluene sulfonyl fluoride, lithium fluoride and 12-Crown-4. This methodology was proved to be efficient by preparting geranyl fluoride, neryl fluoride, cinnamyl fluoride, E, E-farnesyl fluoride, retinyl fluoride and 4-fluoro-2-methyl-6-(ptolyl)-2-heptene.

• Bulletin of the Korean Chemical Society
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• 제16권8호
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• pp.696-698
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• 1995