• Clinics in Shoulder and Elbow
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• 제23권3호
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• pp.136-143
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• 2020

Background: The purpose of this study was to investigate the clinical differences between open reduction and plate fixation via a deltopectoral approach with allogenous fibular bone graft and a minimally invasive plate osteosynthesis (MIPO), in Neer's classification two-, threepart proximal humeral fractures. Methods: In this retrospective study, 77 patients with two-, three-part proximal humeral fractures were treated at two different institutions. Clinical and radiological evaluations were performed in 39 patients, who underwent MIPO at one institution (group A), and 38 patients, who underwent a deltopectoral approach with allo-fibular bone graft (group B) at another institution. The results between the groups were compared. Results: The MIPO technique was significantly less time consuming and caused less bleeding than the deltopectoral approach with allo-fibular bone graft (P<0.05). The duration of the fracture union was significantly reduced in group A (14.5±3.4; range, 10-22 weeks) compared to group B (16.4±4.3; range, 12-28) weeks (P<0.05). There were no statistically significant differences between the two groups when evaluating the visual analog scale and Constant scores between the two groups, 1 year postoperatively. In radiological evaluation, there was no difference in radiological outcomes between the two groups. There were no statistically significant differences in malunion between the two groups. Conclusions: The MIPO technique and deltopectoral approach with allo-fibular bone graft for two-, three-part proximal humeral fractures, show similar clinical and radiological results. However, allogenous fibular grafts require longer surgery, cause more bleeding, and result in longer fracture healing time than MIPO technique.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권3호
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• pp.205-215
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• 2002

The purpose of this study was to evaluate the tissue response in various bone grafting materials, especially xenogenous bone materials in vivo, compare of bone formation capacity of various bone grafting materials on rat skull defects and evaluate the effect of Hyaluronic acid on healing of human Demineralized Freezed Dried Bone allogenous graft (DFDBA) materials in rat calvarial defects. 30 Sprague-Dawly rats were divided into 4 groups. $7{\times}7mm$ size bony defect were artificially prepared in the calvaria (both parietal bone) of all 30 rats and follwed group grafting of autogenous bone graft on right side and allogenic DFDBA on left side bone graft (rat DFDB) in 15 control group, but in 15 experimental group, xenograft (human DFDB) on left side, hyaluronic acid treated with xenograft on right side. Sequential sacrifices was performed at 1, 2, 4, 6, 8 weeks of experiment. These specimens were stained with H&E and MT stain, and then histologic analysis under light microscope was carried out. There were inflammatory reaction in all graft material during early stage. Autogenous and Allogenous DFDBA graft group observed inflammatory reaction at 1 week. Xenograft group persistant inflammatory reaction until 4 weeks, but in HA treated xenograft group inflammatory reaction was decreased at 2 weeks. Osteoblastic activity in control group was begun at 2 week, xenograft group was delayed at 6 weeks, however HA treated xenograft group was begun at 4 weeks. At 2 week, mild osteoclastic activity were observed in all xenograft group not in concerned to HA, but there was no difference each group after 4 weeks. There are most activated angiogenesis around graft mateirals in xenograft group at 2 weeks, but in HA treated xenograft group, decreased angiogenesis was observed at same time. Bone formation and bone maturation of xenograft group, there was no difference in HA treatment, was less than control group. Fibrosis around xenograft materials were observed until 6 weeks, there was no difference between xenograft and HA treated groups.

• Clinics in Shoulder and Elbow
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• 제23권3호
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• pp.152-155
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• 2020

Periprosthetic fracture after total elbow replacement surgery is a difficult complication to manage, especially when it comes together with implant loosening. If stem revision and internal fixation of the periprosthetic fracture are performed simultaneously, this would be a very challenging procedure. Most of total elbow replacement implants are cemented type. Cement usage at periprosthetic fracture site may interfere healing of fractured site. Authors underwent internal fixation with use of locking plate and cerclage wire for periprosthetic fracture, allogenous fibular strut bone inserted into the humerus intramedullary canal allowing the fractured site to be more stable without cement usage. At 10-month follow-up, the complete union and good clinical outcome was achieved. We present a novel technique for treating periprosthetic fracture with implant loosening after total elbow replacement surgery, using intramedullary allogenous fibula strut bone graft.

• Journal of Korean Neurosurgical Society
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• 제62권4호
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• pp.450-457
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• 2019

Objective : Anterior cervical discectomy and fusion (ACDF) is commonly used surgical procedure for cervical degenerative disease. Among the various intervertebral spacers, the use of allografts is increasing due to its advantages such as no harvest site complications and low rate of subsidence. Although subsidence is a rare complication, graft collapse is often observed in the follow-up period. Graft collapse is defined as a significant graft height loss without subsidence, which can lead to clinical deterioration due to foraminal re-stenosis or segmental kyphosis. However, studies about the collapse of allografts are very limited. In this study, we evaluated risk factors associated with graft collapse. Methods : We retrospectively reviewed 33 patients who underwent two level ACDF with anterior plating using allogenous bone graft from January 2013 to June 2017. Various factors related to cervical sagittal alignment were measured preoperatively (PRE), postoperatively (POST), and last follow-up. The collapse was defined as the ratio of decrement from POST disc height to follow-up disc height. We also defined significant collapses as disc heights that were decreased by 30% or more after surgery. The intraoperative distraction was defined as the ratio of increment from PRE disc height to POST disc height. Results : The subsidence rate was 4.5% and graft collapse rate was 28.8%. The pseudarthrosis rate was 16.7% and there was no association between pseudarthrosis and graft collapse. Among the collapse-related risk factors, pre-operative segmental angle (p=0.047) and intra-operative distraction (p=0.003) were significantly related to allograft collapse. The cut-off value of intraoperative distraction ${\geq}37.3%$ was significantly associated with collapse (p=0.009; odds ratio, 4.622; 95% confidence interval, 1.470-14.531). The average time of events were as follows: collapse, $5.8{\pm}5.7months$; subsidence, $0.99{\pm}0.50months$; and instrument failure, $9.13{\pm}0.50months$. Conclusion : We experienced a higher frequency rate of collapse than subsidence in ACDF using an allograft. Of the various preoperative factors, intra-operative distraction was the most predictable factor of the allograft collapse. This was especially true when the intraoperative distraction was more than 37%, in which case the occurrence of graft collapse increased 4.6 times. We also found that instrument failure occurs only after the allograft collapse.

• 대한정형외과스포츠의학회지
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• 제8권2호
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• pp.115-120
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• 2009

목적: 배측 분쇄가 있는 원위부 요골 골절에서 세가지 수술법에 따른 결과를 알아보고자 하였다. 대상 및 방법: 2006년 4월부터 2009년 5월 사이의 60세 이상의 배측 분쇄가 있는 원위부 요골 골절이 있으면서 불안정성을 보인 환자 49명을 대상으로 하였다. 수술 1년 후까지의 방사선학적 추시관찰을 통하여 골절 정복의 유지 여부 및 Mayo Wrist Score를 통한 임상적 결과를 비교하였으며, 일원배치 분산분석(One-Way ANOVA)을 통하여 연관성을 검정하였다. 결과: 세군 모두에서 수술 직후에는 만족스러운 정복을 얻을 수 있었으나, 추시 소견상 외고정장치 단독으로 고정시에는 외고 정장치에 동종골 이식을 추가한 군 및 수장측 잠김 압박 금속판을 사용한 군에 비해서 유의하게 정복 소실이 있음을 확인하였다.(p<0.05) Mayo Wrist Score는 세군 모두에서 의미있는 차이는 없었다. 결론: 배측 분쇄가 심한 원위부 요골의 관절내 골절에서 외고정 장치만 사용한 치료시에는 해면골 결손으로 인한 정복유지의 어려움이 있어 불충분한 치료로 판단된다.

• Clinics in Shoulder and Elbow
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• 제23권3호
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• pp.156-158
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• 2020

PHILOS plate fixation in osteoporotic proximal humerus fracture of old age is well-known for high complication rate, especially metal failure, providing various augmentation techniques, such as calcium phosphate cement, allogenous or autologous bone graft. We report a case of polymethyl methacrylate augmentation to provide appropriate reduction with a significant mechanical support. This can be a treatment option for displaced unstable osteoporotic proximal humerus fracture with marked bony defect.

• Journal of Korean Neurosurgical Society
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• 제30권12호
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• pp.1388-1393
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• 2001

Objective : In the retrospective analyzing 19 consecutive patients with subaxial cervical spine(C3~T1) injury treated by posterior cervical fixation and fusion, clinical manifestation, radiologic finding, operative technique, and postoperative results following 6 months were analyzed. Materials and Methods : Most common fracture level was C4-5, mean age 41, and male to female ratio 13 : 6. The most common cause of injury was motor vehicle accident(17 cases). In 19 cervical procedures, interspinous triple wiring was done in 14 cases, lateral mass plating in 5 cases, and additional anterior fusion in 2 cases. Results : Twelve weeks after operation, all cases were reviewed by plain cervical radiogram. In 17 cases that treated by posterior fusion only, 14 cases(81%) had kyphotic angle change less than $5^{\circ}$, 2 cases(12%) $5-20^{\circ}$, and 1 case(6%) more than $20^{\circ}$. Overall fusion rate was 88%, and there was no significant difference of bone fusion rate between autogenous bone graft and allogenous bone graft. Conclusion : In the case of severe posterior column injury or displacement, posterior approach seems superior to anterior approach, but in the case of combined anterior column injury, anterior approach is considered necessary. In this study, posterior fixation and fusion might be acceptable procedure for subaxial cervical fracture and dislocation, owing to its high fusion rate, low kyphotic angulation and low operation related complication rate.

• 대한치과보철학회지
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• 제35권1호
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• pp.95-102
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• 1997

Ameloblastoma is the most agrressive ofht odontogenic tumors and it arises from the dental lamina or the derivatives of lamina. Ameloblastoma is a benign but locally invasive neoplasm consisting of proliferating odontogenic epithelium lying in a fibrous stroma. Usually the ameloblastomas are diagnosed in the forth and fifth decardes. Over 80% of them occur in the mandible, the remainder in the maxilla. The preferred treatment for ameloblastoma is radical excision, conserving(when possible. the inferior border of the mandible. The functional and esthetic rehabilitation of the partially edentulous patient may prevent the remaining structures from supporting conventional prosthetic treatment. Patients with long edentulous spans, malpositioned teeth, residual ridges defects and high muscle attachments may be offered an osseointegrated fixed prosthesis. Osseointegrated dental implants provide a viable alternative of tooth replacement. This is a case report of 16 year old female with ameloblastoma. We treated patient with radical excision, conserving the inferior border of the mandible and allogenous bone graft. The defected residual ridge area was reconstructed implants(Steri-Oss Implant System). the result was satisfactory.

• 대한관절경학회지
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• 제9권2호
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• pp.132-136
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• 2005

목적: 전방 십자 인대 파열 환자를 대상으로 자가 골-슬개건-골과 동종 아킬레스 건을 이용해 관절경적 재건술을 시행하고 이식건에 따른 임상 경과를 분석하고자 한다. 대상 및 방법: 2002년 8월부터 2004년 4월까지 본원에서 전방 십자 인대 손상 환자를 대상으로 관절경적 재건술을 시행한 83례 중 1년 이상 추시가 가능했던 60 명의 환자를 대상으로 하였다. 제 I 군(32례)은 자가 골-슬개건-골 이식물을 이용하고, 제 II 군(28례)은 동종 아킬레스건 이식술을 이용하여 재건술을 시행하였다. 수술시 평균 환자의 나이는 33.5 세였고, 평균 추시 기간은 18 개월(12 개월${\sim}$30 개월)이었다. 환자의 주관적 평가로 수술 후 1년째 Lysholm knee scoring scale을 사용하였고 객관적 평가로 KT-2000TM arthrometer(MED metric, USA)를 사용하였다. Chi-square 경향 분석, 독립적 T 검정 방법으로 비교 분석하였고, 통계 프로그램은 SPSS 10.0 version을 이용하였다. 결과: 수술 후 1년째 KT-2000 arthrometer에서는 30 Ibs부하시 정상측과 비교하여 술 후 자가 골-슬개건-골군에서 1.53 mm, 동종 아킬레스건군에서 1.38 mm의 차이를 보여 만족스러운 결과를 보였다. 최종 Lysholm knee scoring scale을 이용한 평가 결과는 자가 골-슬개건-골군이 평균 93.9점(good), 동종 아킬레스 건군이 94.8점(good)이었으나 통계적 의미는 없었다. 결론: 저자들의 경우 Lysholm 점수, KT-2000 관절 계측 결과 등은 동종 아킬레스건군에서 자가 골-슬개건-골군과 비교하여 통계학적인 의미는 없었다. 전방 십자 인대 재건술시 이식건의 선택은 환자 개개인의 특성과 상황에 따라 달라져야 할 것으로 생각되며, 동종 아킬레스건도 임상적으로 좋은 결과를 보여 선택적으로 자가 이식건의 대체물로 사용될 수 있으리라 사료된다.

• 대한관절경학회지
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• 제5권2호
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• pp.74-79
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• 2001

목 적 : 후방 십자 인대 손상의 치료로서 관절경적 후방 십자 인대 재건술을 시행하여 임상 결과를 분석하고자 하였으며, 특히 추시상 후방 불안정의 재발 여부와 자가 골-슬개건-골을 이용하여 재건한 경우 및 동종 이식물을 이용한 결과를 비교 분석하였다. 대상 및 방법 : 1994년 1월부터 1999년 5월까지 본원에서 수술 치료한 총 34례의 후방 십자 인대 손상의 환자 중에서 전외측 다발만을 관절경적으로 재건술을 시행하고 12개월 이상 최종 추시가 가능했던 25례 중 자가 반건양건을 이용한 1례를 제외한 24례를 대상으로 하였으며, 24례 중 자가 골-슬개건-골을 이용하여 재건한 경우를 제 I군(11례), 동종 아킬레스 건을 이용하여 재건한 경우를 제 II군(7례), 동종 골-슬개건-골을 이용하여 재건한 경우를 제 III군(6례)으로 하였다. 평가 방법은 24례 모두를 International Knee Documentation Committee(IKDC) knee ligament standard evaluation form, Lysholm knee scoring scale을 이용하여 세 집단을 비교하였으며 전 후방 안정도의 측정을 위해서 $KT-2000^{TM}$ knee ligament arthrometer MED metric, USA(KT-2000)를 사용하였다. Kruskal-Wallis test와 Mann-Whitney U(Wilcoxon Rank Sum) 검정법을 이용하여 세 집단을 비교 통계 분석하였다. 결과 : IKDC 최종 평가상 B(거의 정상)이상은 전체 24례 중 11례$(46\%)$로 만족스러운 결과는 아니었고, KT-2000으로 측정시 양측 비교하여 6mm 이상 차이가 나는 경우는 제 I군 4례$(36\%)$, 제 II군 2례$(29\%)$, 제 III군 2례$(33\%)$에서 후방 불안정성을 보였다. Lysholm knee scoring scale을 이용한 평가 결과는 제 I군이 평균 78점 (fair), 제 II군이 75점(fair), 제 III군이 76점(fair)이었다. 재료에 따른 각 군간의 객관적, 주관적 결과의 차이는 보이지 않았다. 결론 : 후방 십자 인대 손상시 불안정의 정도가 심하지 않은 단독 손상을 제외하고는 관절경적 재건술이 보편화 되는 추세이나, 보다 정확한 수술 술기와 동반 손상에 대한 치밀한 치료 계획이 요구되며, 새로운 시도와 그에 따른 많은 연구가 필요할 것으로 생각된다.