• 대한한의학원전학회지
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• 제6권
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• pp.41-53
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• 1993

The theory of 4 great doctors in Geum Won era has been considered as a most scientific medicine after SangHanRon of Jang, Jung Kyung. And it influence for all the later medical theory and practice. I have found a common points between their Fire and Fever pathology and constitutional pathology of Li, Je Ma. The results obtained are as follows. 1. On the Viewpoint of medical history, there is common points in the fact that the start of Geum Won 4 great doctor' principle had been drived from awakening of the abuse of warm and hot herbs based on Hwa Je Guk Bang in the last stage of Song dynasty, and that the appearance of Sa Sang medicine was from the scientific reflection against the currency of the animation by warm herbs which was popular in the Jo Sun dynasty. 2. The theory of Fire and Fever pathology of 4 great doctors has been fixed in the principle of Cold and Fever pathology of viscera and bowel in the Sa Sang medicine. 3. The pathological meaning of 'internal fire' in the conculusion by 4 great doctors has got scientific fruit by Sa Sang medicine in its theory of four constitutional psychology and the formation of four visceras. 4. It is considered that the study of DongUiSuSeBoWon is needed for the relation with former medical theories.

• 한국의상디자인학회지
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• 제19권2호
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• pp.117-128
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• 2017

This study confirmed the types of shopping information sources during travel abroad, and developed a profile of tourists in terms of demographics, travel, and shopping behavior. Shopping information sources and characteristics of shopping products were identified first. Thereafter, travelers were segmented by their information-seeking behavior. An online survey method was used to get data from Korean vacationers in their 20s-50s, while factor analysis, cluster analysis, ${\chi}^2$ test and ANOVA were applied to analyze data. The results were as follows. First, the shopping information sources of overseas tourists were composed of four factors including sources from travel agents/media, information from travel books and local sources, and word-of-mouth sources. Also, four factors in product types and four product attributes were identified. Second, tourists were clustered into two groups, active and passive shopping information seekers, based on shopping source behavior. Third, two groups differed in terms of demographics, showing an older age and higher income for active shopping source seekers. Active shopping information users tended to join package trips with family members, and they were more satisfied with the trip. With regard to shopping, active shopping source seekers spent more money for shopping and preferred all kinds of shopping goods with an emphasis on travel shopping. In conclusion, shopping information sources seemed to be a meaningful tool for segmenting tourists. Rich, older, family tourists would be an major target market for local retailers.

• 한국초지조사료학회지
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• 제12권4호
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• pp.232-238
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• 1992

To understand the basic information on the management and utilization of reed canarygrass (Phalaris arundinacea L.), four cultivars of Palaton. Venture, Castor and Frontier (control) were compared for growth characteristics, dry matter (DM) yield and nutritive value, 1990 to 1992. The reed canarygrass was harvested four times annually, at soiling stage. The average plant height at harvest was 60 cm in Frontier, 57 cm in Palaton and Venture, and 52 cm in Castor. Initial heading and heading date in 1990 were ca. 21 May and 29 May, respectively, regardless of cultivar. The highest yield (12.495 kg/ha) in 1990 was observed by Frontier. In 1991. Palaton. Venture and Frontier outyielded Castor significantly, and the yields of all cultivars in 1992 were not significant, ranged from 11,460 kg (Castor) to 12,298 kg/ha (Palaton). On an average for three years, Palaton (10,592 kg), Venturc (10,405 kg) and Frontier (1 1,277 kg/ha) produced more forages than Castor. In Frontier the percentage of DM distribution at first harvest (spring) was highest (32.4%). However, the distributions at third (summer) and fourth (autumn) harvest were high in Palaton and Venture, compared with Frontier. The nutritive value of reed canarygrass was not significantly different among cultivars, and the percentage of weeds was slightly high in Castor reed canarygrass.

• Structural Engineering and Mechanics
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• 제46권2호
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• pp.179-196
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• 2013

An experimentally measured single footfall trace (SFT) from a walking subject needs to be extended into a continuous force curve, which can then be used as load for floor vibration serviceability assessment, or on which further analysis like discrete Fourier transform can be conducted. This paper investigates the accuracy, applicability and parametrical sensitivity of four extension methods, Methods I to IV, which extends the SFT into a continuous time history by the walking step rate, stride time, double support proportion and the double support time, respectively. Performance of the four methods was assessed by comparing their results with the experimentally obtained reference footfall traces in the time and frequency domain, and by comparing the vibrational response of a concrete slab subjected to the extended traces to that of reference traces. The effect of the extension parameter on each method was also explored through parametrical analysis. This study finds that, in general, Method I and II perform better than Method III and IV, and all of the four methods are sensitive to their extension parameter. When reliable information of walking rate or gait period is available in the test, Methods I or II is a better choice. Otherwise, Method III, with the suggested extension parameter of double support time proportion, is recommended.

• Journal of Microbiology and Biotechnology
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• 제10권2호
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• pp.169-175
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• 2000

The filamentous soil bacterium Streptomyces coelicolor is known to produce four distinct antibiotics. The simultaneous global regulation for the biosynthesis of those four antibiotics was previously confirmed by absA and absB mutations that blocked all four antibiotics' biosynthesis without influencing their morphological differentiation. To study the complex regulatory cascade that controls the secondary metabolism in Streptomyces, a new abs-like mutation was characterized. namely absR, which is slightly leaky on a complete R2YE medium, yet tight on a minimal medium. A genetic analysis of the absR locus indicated that it is located at 10 o'clock on the genetic map, near the site of absA. A cloned copy of the absA gene that encoded bacterial two-component regulatory kinases did not restore antibiotic biosyntheis to the absR mutant. Accordingly, it is proposed that absR is another abs-type mutation which is less tight than the previously identified absA or absB mutations income medium conditions, and can be used to characterize another global regulatory gene for secondary metabolete formation in S. coelicolor.

• Toxicological Research
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• 제18권2호
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• pp.117-127
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• 2002

Saururus chinensis Baill has been used in Korean folk medicine for the treatment of various diseases such as edema, Jaundice, and furuncle. The components of this plant were extracted into four fraction. Among the four fraction, hexane and ethyl acetate fraction were highly toxic to 3T3 mouse embryo fibroblast and Raw 264.7 mouse macrophage, but n-butanol and residue fraction did not show any toxic effect to those cell lines. n-Butanol and residue fraction exhibited antioxidant effects on hydro-gen peroxide, hydroxyl radical, and superoxide anion directly in vitro and in the 3T3 fibroblasts. All the four fractions inhibited lipid peroxidation measured by thiobarbituric acid reactive substances (TBARS) formation. In addition, n-butanol and residue fraction showed inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide production, and also down-regulated inducible nitric oxide synthase (iNOS) mRNA transcription 6 h after LPS stimulation in Raw 204.7 cells. Only n-butanol fraction, which mainly consists of flavonoids, inhibited NF-kB activation by decreasing IkBa degradation 90 min after LPS stimulation. horn the results, it is suggested that this plant could be a good candidate material for drug development based on its antioxidant and/or anti-inflammatory constituents.

• 여성건강간호학회지
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• 제23권3호
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• pp.155-165
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• 2017

Purpose: The aim of this study was to understand the hand-on breast massage techniques used by well-known experts in breastfeeding clinics. Methods: A qualitative multiple-case design was applied that involved a feasibility test. Four experts sampling qualitative data collected by observing participants and in individual interviews were analyzed by content analysis, linking data to the propositions, and cross-case pattern matching. This study explored differences within and between cases, and the possibilities of replicating findings across cases. Thirty-nine postpartum women participated voluntarily in the feasibility test, which investigated the usability of four massage techniques. Results: The four techniques showed considerable similarities in terms of the application of stimulation to the breast base and increased flexibility of the wired flexible body, which was the core mechanism underlying the techniques. The breast management strategies were consistent with existing practice guidelines with the exception of using cold cabbage to control engorgement pain. There was insufficient scientific evidence for supporting the massage techniques used by the experts. All of the techniques showed 100% education completeness, but application rates were higher for self-control-oriented techniques. Conclusion: The massage techniques applied by experts in breastfeeding were based on hypotheses and self-control techniques are feasible to apply in practice.

• 한국의류학회지
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• 제31권11호
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• pp.1500-1509
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• 2007

The purpose of this study was to observe lifestyle of female consumers aged 15-25. Also it was to measure brand awareness, to determine purchase criteria in fashion magazine, and to determine promotion preferences according to lifestyle segmentation variables. We distributed 600 questionnaires and 475 reliable questionnaires were used for a statical analysis. Data analyses were conducted with SPSS program on the frequency mean value, Chi-square test, Cluster analysis, and Factor analysis. We classified four clusters such as individual style seekers, trend seekers, promotion/good appearance seekers, and low fashion interest group, based on lifestyle variables. There was a significant difference in brand awareness in Vogue Girl, Cosmo Girl, Elle, Figaro, Ecole magazine among four clusters. There was a significant difference in such purchase criteria as favorable cover models, good "burok" which is a magazine supplement, brand names, and price among four clusters. In addition, the results of ANOVA represent that there was a significant difference in preferred types of promotion such as discount price, clothing gifts, fashion accessary gifts and hair tool gifts. However, the first ranked preferred one was a cosmetic gift in all the magazines, which favored more by trend seeker group.

• Restorative Dentistry and Endodontics
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• 제14권2호
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• pp.103-110
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• 1989

The purpose of this study was to evaluate the cleansing effect of Glyoxide on the dentinal walls of the root canal. Fourty teeth were divided into four groups and the canals in each group were individually enlarged with K-file by step-back technic and irrigated with one of four irrigants. The four used irrigants were Glyoxide (Marion lab. U.S.A.) in combination with 3.5% sodium hypochlorite, 3.5% sodium hypochlorite, 3.5% sodium hypochlorite in combination with 3% hydrogen peroxide and normal saline solution. All the irrigants were used in conjunction with instrumentation as they would be during clinical conditions. After final irrigation, the canals were dried with paper points and the teeth were split longitudinally. The cleaness of canal walls according to the size and the level of canals were evaluated under steroscope by t analysed statistically The results were as follows. 1. The use of 3.5% sodium hyphochlorite in combination with 3.0% hydrogen peroxide revealed the most clean canal surface regardless of the size of canal at apical third of root canal (p < 0.05). 2. Glyoxide in combination with 3.5% sodium hyphchlorite showed no significant difference in cleaning effect of canal surface compared with 3.5% sodium hypochlorite and normal saline solution at the apical third of narrow canal. 3. Glyoxide in combination with 3.5% sodium hypochlorite revealed no significant difference in debridement of canal walls compared with 3.5% sodium hypochlorite in combination with 3% hydrogen peroxide and saline solution at the middle third of narrow and large canals.

• 국제물리치료학회지
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• 제10권2호
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• pp.1785-1790
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• 2019

Background: Lumbar disc herniation (LDH) causes neurological symptoms by compression of the dura mater and nerve roots. Due to the changed in proprioception inputs that can result in abnormal postural pattern, delayed reaction time, and changed in deep tendon reflex. Objective: To investigate the effects of lumbar stabilization exercises on motor neuron excitability and neurological symptoms in patients with LDH. Design: Randomized Controlled Trial (single blind) Methods: Thirty patients with LDH were recruited; they were randomly divided into the balance center stabilization resistance exercise group (n=15) and the Nordic walking group (n=15). Each group underwent their corresponding 20-minute intervention once a day, four times a week, for four weeks. Participants' motor neuron excitability and low back pain were assessed before and after the four-week intervention. Results: There were significant differences in all variables within each group (p<.05). There were significant differences between the experimental and control groups in the changes of upper motor neuron excitability and pain (p<.05), but not in the changes of lower motor neuron excitability and Korean Oswestry Disability Index. Conclusion: Lumbar stabilization exercises utilizing concurrent contraction of deep and superficial muscles improved low back function in patients with LDH by lowering upper motor neuron excitability than compared to exercises actively moving the limbs. Lumbar stabilization exercises without pain have a positive impact on improving motor neuron excitability.