• Journal of the Korean Society for Precision Engineering
• /
• v.16 no.9
• /
• pp.89-95
• /
• 1999

The compression behavior of semi-solid materials in studied from a viewpoint of yield criteria and analysis methods. To describe the behavior of materials in semi-solid state, several theories have been proposed by extending the concept of plasticity of porous compressible materials. in the present work, the upper-bound method and the finite element method are used to model the simple compression process using yield criteria of Kuhn and Doraivelu. Segregation between solid and liquid which cause defect of product is analysed for Sn-15%Pb alloy is compared with the experimental result of Charreyron et al..

• Transactions on Electrical and Electronic Materials
• /
• v.7 no.1
• /
• pp.26-29
• /
• 2006

We present the structural, magnetic, and electrical properties in the (Al,Mn)N films with various Mn concentrations grown by plasma-enhanced molecular beam epitaxy. X-ray diffraction analyses reveal that the (Al,Mn)N films have the wurtzite structure without secondary phases. All (Al,Mn)N films showed the ferromagnetic ordering. Particularly, ($Al_{1-x}Mn_{x}$)N film with x = 0.028 exhibited the highest magnetic moment per Mn atom at room temperature. Since all the films exhibit the insulating characteristics, the origin of ferromagnetism in (Al,Mn)N might be attributed to either indirect exchange interaction caused by virtual electron excitations from Mn acceptor level to the valence band within the samples or a percolation of bound magnetic polarons arisen from exchange interaction of localized carriers with magnetic impurities in a low carrier density regime.

• Molecules and Cells
• /
• v.42 no.8
• /
• pp.597-603
• /
• 2019

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a core enzyme of the aerobic glycolytic pathway with versatile functions and is associated with cancer development. Recently, Kornberg et al. published the detailed correlation between GAPDH and di- or monomethyl fumarate (DMF or MMF), which are well-known GAPDH antagonists in the immune system. As an extension, herein, we report the crystal structure of MMF-bound human GAPDH at $2.29{\AA}$. The MMF molecule is covalently linked to the catalytic Cys152 of human GAPDH, and inhibits the catalytic activity of the residue and dramatically reduces the enzymatic activity of GAPDH. Structural comparisons between $NAD^+$-bound GAPDH and MMF-bound GAPDH revealed that the covalently linked MMF can block the binding of the $NAD^+$ cosubstrate due to steric hindrance of the nicotinamide portion of the $NAD^+$ molecule, illuminating the specific mechanism by which MMF inhibits GAPDH. Our data provide insights into GAPDH antagonist development for GAPDH-mediated disease treatment.

• Bulletin of the Korean Mathematical Society
• /
• v.44 no.1
• /
• pp.173-176
• /
• 2007

The non-existence is proved of four-dimensional mod 2 semisimple representations of Gal ($\=\mathbb{Q}/\mathbb{Q}$) which are unramified outside 2.

• Applied Biological Chemistry
• /
• v.45 no.3
• /
• pp.152-156
• /
• 2002

Soils near abandoned zinc mines were known to be contaminated with arsenic-rich mining by-products. To examine the potential impacts of arsenic- contaminated soils on plant growth, surface soils were subjected to sequential extraction. Results revealed that 54% and 74% total As and 74% total extractable As were bound to iron hydrous oxide, and water soluble fraction was below detection limit. Arsenic faction extracted using the Koran standard method(dissolution of metals via treatment of 1 N HCI) was strongly correlated with the Fe-bound As fraction ($r^2=0.884**$). Arsenic level in rice plant roots was the highest with a maximum value of 154.9 mg/kg, whereas it was below 0.6 mg/kg in grains. Arsenic level in rice plant roots was strongly correlated with those of Al-bound As ($r^2=0.821**$) and 1N HCI-extractable As levels ($r^2=0.801**$).

• Ocean and Polar Research
• /
• v.32 no.3
• /
• pp.177-186
• /
• 2010

A sequential extraction technique was used to study sediment phosphorus speciation and its relative importance in the intertidal flat of Keunso Bay during summer and winter for a better understanding of the phosphorus cycle and bioavailability in intertidal sediments. Loosely sorbed P contents were the lowest among the five P-pools and showed little seasonal or spatial variation. Although Fe-bound P contents were almost constant in winter, they decreased rapidly with sediment depth in summer. The dissolution of Fe oxides, used as an oxidant for the anaerobic respiration, ascribed the rapid decrease of Fe-bound P in summer. Al-bound P contents displayed little seasonal variation, but showed a large spatial variation, with higher values in the upper intertidal flat. Comprising about 50% of total P, Ca-bound P contents were the highest among the five P-pools. Ca-bound P contents were higher in winter than summer, but did not exhibit a clear spatial variation. Organic P contents were higher in summer than winter, which was associated with higher primary production and clam biomass in summer. Organic P contents were higher in the lower intertidal flat than the upper intertidal flat. In Keunso Bay, bioavailable P contents of the intertidal flat comprising about one third of total P ranged from 2.41 to 5.09 ${\mu}molg^{-1}$ in summer and 3.82 to 5.29 ${\mu}molg^{-1}$ in winter. The bioavailability of P contents was higher in the lower intertidal flat than the upper intertidal flat, which was attributed to the large clam production in the lower intertidal flat.

• Bulletin of the Korean Chemical Society
• /
• v.28 no.5
• /
• pp.811-815
• /
• 2007

A series of bispyrenyl-polyether have been synthesized and investigated as a fluorescent chemosensor for metal ions. The results showed that bispyrenyl-polyether system is selective towards Al3+ ion over other ions tested. In free ligand, excited at 343 nm, it displays a strong excimer emission at around 475 nm with a weak monomer emission at 375 nm. A ratiometry of monomer (375 nm) increase and excimer (475 nm) quenching was shown only when Al3+ ion is bound to ligand, because two facing pyrene groups form a less efficient overlap of π?π stacking compared with that of free ligand.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.26 no.3
• /
• pp.58-66
• /
• 2003

The cut tree approach of Montreuil and Ratliff [16] and eigenvector approach [10] are used to automatically draw a feasible facility layout with aisle structure. The department arrangement can minimize an aisle distance criterion considering door locations and dimension constraints. The aisle distance is measured by the door to door distance between departments. An eigenvector and cut tree approaches [1] are implemented based on the branch and bound technique in Kim et al. [2] in order to obtain feasible layouts. Then, the algorithm to fix the door location of each department is developed. After the door locations are determined, the factory layout is evaluated in terms of aisle distance. The aisle structure is obtained by expanding the original layout. The solution is kept until we will find better factory layout. The proposed approach based on the branch and bound technique, in theory, will provide the optimal solution. If the runs are time and/or node limited, the proposed method is a strong heuristic. The technique is made further practical by the fact that the solution is constrained such that the rectangular shape dimensions length(l) and width(w) are fixed and a perfect fit is generated if a fit is possible.

• The Bulletin of The Korean Astronomical Society
• /
• v.39 no.2
• /
• pp.70.2-70.2
• /
• 2014

Galaxy clusters, the largest gravitationally bound systems, are an important means to place constraints on cosmological models. Moreover, they are excellent places to test galaxy evolution models in connection to the environments. To this day, massive clusters have been found unexpectedly(Kang & Im 2009, Durret et al. 2011, Tashikawa et al. 2012) and evolution of galaxies in cluster have been still controversial (Elbaz et al. 2007, Cooper et al. 2008, Tran et al. 2009). Finding galaxy cluster candidates in a wide, deep imaging survey data will enable us to solve the such issues of modern extragalactic astronomy. We have used multi-wavelength data from the UKIRT Infrared Deep Sky Survey Deep Extragalactic Survey (UKIDSS DXS/J and K bands), Spitzer Wise-area InfraRed Extragalactic survey (SWIRE/two mid-infrared bands), the Panoramic Survey Telescope and Rapid Response System (PAN-STARRS/ g, r, i, z, y bands) and Infrared Medium-deep Survey(IMS/J band). We report new candidates of galaxy clusters and properties of their member galaxies in one of the wide and deep survey fields ELAIS-N1, European Large Area ISO Survey North1, covering sky area of $8.75deg^2$.

• The Bulletin of The Korean Astronomical Society
• /
• v.39 no.1
• /
• pp.48.1-48.1
• /
• 2014

Galaxy clusters, the largest gravitationally bound systems, are an important means to place constraints on cosmological models. Moreover, they are excellent places to test galaxy evolution models in connection to the environments. To this day, massive clusters have been found unexpectedly(Kang & Im 2009, Durret et al. 2011, Tashikawa et al. 2012) and evolution of galaxies in cluster have been still controversial (Elbaz et al. 2007, Cooper et al. 2008, Tran et al. 2009). Finding galaxy cluster candidates at z>1 in a wide, deep imaging survey data will enable us to solve the such issues of modern extragalactic astronomy. We report new candidates of galaxy clusters and their physical properties in one of the wide and deep survey fields, European Large Area ISO Survey North1(ELAIS-N1) and North2(ELAIS-N2) fields, covering sky area of and each. We also suggest a new useful color selection technique to separate 1 < z < 2 galaxies from low-z galaxies by combining multi-wavelength data from the UKIRT Infrared Deep Sky Survey Deep Extragalactic Survey (UKIDSS DXS/J and K band), Spitzer Wise-area InfraRed Extragalactic survey (SWIRE/two mid-infrared bands), Canada France Hawaii Telescope (CFHT/z band), Issac Newton Telescope(INT/ u, g, r, i, z band) and Infrared Medium-deep Survey(IMS/J band).