Benzidine Industry in Korea has started after Japan has banned its production in early 1970's, and it has been in operation in Korea for over 20 years. However, it is not known yet whether any bladder cancer has developed from benzidine exposure. This study was done to screen benzidine-exposed workers for bladder cancer, and to examine the feasibility of employing screening test at the workplace. All the workplaces that manufacture or use benzidine for more than 20 years in Korea have been covered in this study, and they include 2 benzidine manufacturing factories, 5 benzidine using factories, as well as 2 benzidine free factories as an outside control. In total, 516 workers were screened with urine stick test and urine cytology test for the evidence of hematuria and abnormal urothelial cells. Each worker was also asked about risk factors and symptoms of bladder cancer including past medical history, smoking, medication and occupational history Benzidine in the air was measured by personal and area sampling. Out of 516 screened workers, 84(16.3%) workers showed positive hematuria in urine stick test, and 7(1.4%) workers showed degenerative cells in urine cytology tests. Those workers with abnormal urine test results who have been exposed to benzidine fo more than 10 years were further screened, and, in total, 23 workers were examined with intra-venous pyelography and cystoscopy. None of those screened had any evidence of bladder cancer When workers with only past hematuria history were included in the positive hematuria group, 96(18.5%) had positive hematuria. On the multiple logistic regression analysis, positive hematuria was significantly associated with benzidine exposure, history of other occupations with elevated bladder cancer risk, pyuria and glycosuria. The association got stronger as direct benzidine exposure was accounted through individual task analysis, and as exposure duration was accounted with tenure analysis. For those with benzidine exposure with more than 10 years of tenure, the odds of having positive hematuria was elevated 2.14(95%C.I is 1.08 to 4.25) times more than for those without exposure. Even though bladder cancer was not detected for several limitations including short observation period, majority of studied workers with short latency, healthy worker effect, and low sensitivity of single screening test in a cross-sectional study, the study results suggest that hematuria screening is a feasible and very useful test for bladder cancer screening among benzidine exposed workers.
Kim, Dohyung;Byun, Kiwhan;Park, Jae-Oh;Lee, Mi-Young;Kim, Eun-A
Journal of Korean Society of Occupational and Environmental Hygiene
/
v.24
no.3
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pp.345-352
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2014
Objectives: This study is aimed to describe the current situation about urinary biomarker N-methylformamide(NMF) for workers exposed to N,N-dimethylformamide(DMF) according to industrial classification. Materials: Special health examination records of the workers who had undergone urinary biological monitoring in 2013 were collected. The numbers and percentage of workers, whose urinary NMF values were above the limit of detection(LOD) and above the biological exposure index(BEI) were calculated. Health relatedness with DMF as judged by their doctors was also described. All description was classified according to the $9^{th}$ Korean Standard Industrial Classification(KSIC). Results: It appeared that most workers exposed to DMF belong to manufacturing section(80.7%). The geometric mean(GM) values of urinary NMF were 6.25 mg/L, 3.54, and 3.86 for the manufacturing section, professional, scientific and technical activities section, and for the construction section respectively. In detail, it seemed that division of textiles(except apparel) (GM 7.51 mg/L), division of leather, luggage and footwear(11.59 mg/L), and division of rubber and plastic products(6.89 mg/L) were highly exposed to DMF with a high percentage of workers with urinary NMF values above BEI. This was probably due to the effect of skin absorption that the division of leather, luggage and footwear showed the highest urine NMF GM. Conclusions: It seemed that workers in manufacture industries such as textile, leather, luggage, footwear, rubber and plastic products were highly exposed to DMF. So, efforts should be focused on those industries in order to effectively diminish worker's exposure. Further studies to compare DMF air-monitoring with bio-monitoring according to industrial classification should be considered.
Growth and anthocyanins of lettuce (Lactuca sativa L., 'Mid-season') grown under LED lamps with blue light in the range of 430-470 nm or with red light in the range of 630-670 nm were analyzed in this study. Cool-white fluorescent light was used a s the control. P hotosynthetic photon flux, p hotoperiod, air temperature, relative humidity, and $CO_2$ concentration in a closed plant production system were $201{\pm}2\;{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$, 16/8 hours (day/night), $22/18^{\circ}C$, 70%, and $400{\mu}mol{\cdot}mol^{-1}$, respectively. At 21 days after light quality treatment, growth characteristics and anthocyanins content of lettuce as affected by the peak wavelength of blue or red LED were significantly different. Among peak wavelengths treated in this stusy, R1 treatment (peak wavelength 634 nm) and R6 treatment (peak wavelength 659 nm) were effective for increasing leaf width, leaf area, shoot fresh weight, and photosynthetic rate of lettuce. B5 treatment (peak wavelength 450 nm) and B4 treatment (peak wavelength 446 nm) increased the anthocyanins concentration and chlorophyll content in lettuce leaves, respectively. Anthocyanins in lettuce leaves increased linearly with decreasing hue value of leaf color and with increasing SPAD value of lettuce leaves. From these results, it was concluded that the red LED with peak wavelengths of 634 nm and 659 nm and the blue LED with peak wavelengths of 450 nm can be used as potential light spectra for increasing the yield and anthocyanins accumulation of leafy vegetable.
Biodegradation of toluene, styrene and hydrogen sulfide as model compounds of volatile organic compounds and odor from waste gas was investigated experimentally in a biotrickling filter. This study focussed on the description of experimental results with regard to operating conditions. The effect of varying $H_2S$ load rate and inlet concentration was investigated under autotropic and mixotropic environmental conditions. The $H_2S$ removal efficiencies of greater than 99% were achieved at $H_2S$ loads below $10g/m^3{\cdot}hr$ for each environment. It was observed that the maximum elimination capacity of mixotrophic filter was achieved a little greater than the one of autotrophic filter. The biofiltration of toluene and styrene in trickling bed was examined under different gas flow rates, load rates, and inlet concentrations. Below $40g/m^3{\cdot}hr$ of toluene loading, the elimination capacity and loading were identical and it was completely destroyed. In high loading of toluene, the biotrickling filter was operated at its maximum elimination capacity. In the inlet concentration of 0.2, 0.5, and $1.0g/m^3$, the maximum elimination capacity of toluene showed 40, 45, and $60g/m^3{\cdot}hr$, respectively. After a short adaptation period, it was demonstrated that the results of styrene in originally toluene adapted bioreactor was similar with the ones of toluene. However, the performance of filer for styrene is generally a little lower than for toluene. The operating conditions (including liquid flow rate etc.) allowing the highest removal efficiency should be determined experimentally for each specific case.
Radurization effects on fried fish meat paste with Co-60 gamma irradiation at 0-5 kGy and physicochemical aspects of the stored samples at low ($3{\pm}1^{\circ}C$, LT) and room ($10-20^{\circ}C$, RT) temperatures were investigated. The initial microbial loads of the samples were $2.2{\times}10^3/g$ in total bacterial count, $2.8{\times}10^2/g$ in yeasts & molds, and $1.0{\times}10^2/g$ in coliform group, respectively. An irradiation dose of more than 3 kGy was shown to be effective for the radurization of stored samples and there is no apparent difference between air and vacuum packaging groups. The chemical components related to the quality underwent similar changes in the nonirradiated and irradiated groups; however, as the storage time was prolonged the quality of nonirradiated samples rapidly deteriorated. Textural parameters of the samples were little affected by the applied doses, and sensory evaluations showed that 3 kGy irradiation was the optimum dose level to extend the shelf-life of fried fish meat paste up to 2 times at RT and 3 to 4 times at LT, respectively compared with the nonirradiated control.
We investigated rhizome yield and growth characteristics of wasabi variety, Daioichigo and Daruma cultured by flowing water from Trout nersery in Pyong Chang. Average temp. of air and water during a year was 14.3, 12.3$^{\circ}C$, respectively in PE film house. Wasabi growth was good and healthy in May and October. Rhizome weight of main stem in Daioichigo was 78.78g per plant and 608kg per l0a, while those of the Daruma was 37.1g per plant and 287kg per l0a. Rate of marketable rhizome was 90% in Daioichigo and 37.5% in Darurna. Rhizome weight of main stem in Daioichigo was increased, up to 21% of the control by the remove of floral axis with two times a year.
Korean Journal of Agricultural and Forest Meteorology
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v.9
no.4
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pp.228-233
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2007
Pear psylla, Caccopsylla pyricola (Homoptera: Psyllidae), is a serious insect pest in pear orchards. C. pyricola overwinters as adults under rough bark scales of pear trees. When the weather warms up in the spring, the overwintered adults become active, climb up to the tree branches, and inhabit on fruit twigs to lay eggs. This study was conducted to develop a forecasting model for the onset of upward-movement of overwintered C. pyricola adults to control them by timely spraying of petroleum oil. The adult population densities were observed under rough barks (B) and on fruit twigs (T) of pear trees. Relative upward-movement rates (R) were calculated as T/(B+T). Low threshold temperatures for the activation of overwintered C. pyricola adults were selected arbitrarily from 5 to $9^{\circ}C$ at a $1^{\circ}C$ interval. Then, the days (D) when daily maximum air temperatures were above each low threshold temperature were counted from 1 February until to the dates with R $\geq$ 0.8. The same methods were applied for the prediction of the first observation of eggs. The variation of coefficients (CV) for the mean Des were lowest with the low threshold temperature of $6^{\circ}C$. At this selected threshold temperature, the upward movement of C. pyricola adults occurred with 12 D and they started laying eggs with 25 D. In the field validation, the model outputs with the $6^{\circ}C$ threshold temperature reasonably well explained the observed data in Suwon and Cheonan in 2002. Practical usages of the model were also discussed.
The purpose of this study is screening of microfloras involved in hydrolysis of seaweed tenella, seaweed fusiforme and green laver. This is a part of studies on the hydrolysis of seaweed using microorganisms. First, about two hundred microflora samples were obtained from mountain, rice field, dry field, sea, seaside and fish market in the vicinity of Yeosu. Thirty-three microflora samples were screened from the destruction of tissue in sea tangle and sea mustard. It was sufficient that results of the naked eye observation were obtained at eight microflora samples as a feces of bull, a decayed pine tree, a soil of dry field, the mud of the banks in a rice field, the water of a ditch in a rice field, the weed of the banks in a rice field, the water in a rice field and leaved in the air. Above all, extraction rate and contents of reducing sugar in extracts of seaweeds added a decayed pine tree(sample No. 8) and the water of a ditch in a rice field(sample No. 27) were showed high value. And the value of chemical analysis of the sample is much better in comparison with control. Accordingly the hydrolysis of seaweed using microorganisms in the inside of these microflora samples can be possible.
Jo, Jin-Ho;Oh, Se-Wook;Kim, Young-Myoung;Chung, Dong-Hyo
Korean Journal of Food Science and Technology
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v.30
no.1
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pp.62-68
/
1998
To develop methods to produce low salt fermented squid with rich flavor and acceptable shelf life, the optimum processing conditions such as water activity of raw material, amounts of NaCl, papain and gucose were investigated. Water activity of squid meat was adjusted to 0.94 (raw meat), 0.90 and 0.88 by cold air blast and each was salted with 3, 5, or 7% NaCl followed by fermenting at $10^{\circ}C$ for 6 weeks. Amino nitrogen was increased rapidly with high water activity and low NaCl concentration. As a result of organoleptic evaluation it was concluded that optimum conditions were to adjust water activity of raw material to 0.90 and to salt with 5% NaCl. When squid meat adjusting water activity to 0.90 was treated with 0.05, 0.1 and 0.5% papain and fermented at $10^{\circ}C$ for 6 weeks, SDS-PAGE pattern showed rapid breakdown of myofibrilar protein with increasing amounts of papain but the treatment with 0.1% enzyme was best organoleptically. pH values of squid meat added with 1 and 2% glucose were maintained lower than control (glucose 0%) but there were no significant differences between the two glucose treatments. Therefore, it was thought that adding of glucose might be extended shelf life of fermented squid with low salt concentration.
Numerical prediction capability has been improved over the decades, but progress of prediction for high-impact weather (HIW) was unsatisfactory. One reason of low predictability for HIW is lack of observation data. The National Institute of Meteorological Research (NIMR) has been performed observation program for improvement of predictability, and reduction in social and economical cost for HIW. As part of this observation program, summer intensive observation program (ProbeX-2009) was performed at the observation-gap areas from 25 August to 6 September 2009. Sounding observations using radiosonde were conducted in the Gisang2000 research vessel (R/V) from the Korea Meteorological Administration (KMA) over the West Sea and the Eardo R/V from the Korea Ocean Research and Development Institute (KORDI) over the South Sea. Observation System Experiment (OSE) is carried out to examine the effect of ProbeX-2009 data. OSEs using Korea Local Analysis and Prediction System (KLAPS) and Weather Research and Forecasting (WRF) Model are conducted to investigate the predictability for a short time forecast. And, OSEs using WRF/3DVAR system and WRF forecast model are conducted to study the predictability for an extended time. Control experiment (K_CTL and CNTL) used only GTS observation and experiment (K_EXP and SWEXP) used ProbeX-2009 data from two system are performed. ETS for 3hr accumulated rainfall simulated by KLAPS-WRF shows that K_EXP is higher than K_CTL. Also, ETS for 12hr accumulated rainfall of SWEXP from 3DVAR-WRF is higher than CNTL. The results indicate that observation over the ocean has positive impact on HIW prediction.
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