• Journal of Microbiology and Biotechnology
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• v.22 no.11
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• pp.1478-1481
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• 2012

Geldanamycin (GM) and its analogs are important anticancer agents that inhibit heat shock protein (Hsp) 90, which is a major chaperone protein in cancer cells. Accordingly, based on interest in obtaining novel natural GM derivatives, the potential of Streptomyces hygroscopicus JCM4427, a GM producer, was explored for novel natural GM derivative(s), resulting in the discovery of new GM analogs as a biosynthetic shunt product and intermediates from its fermentation broth. In this study, the fermentation, isolation, structure determination, and biological activity of the compounds, two new tetracyclic thiazinogeldanamycin (1) and 19-hydroxy-4,5-dihydrogeldanamycin (3), together with the three known 4,5-dihydrothiazinogeldanamycin (2), reblastatin (4), and 17-demethoxy-reblastatin (5), are described.

• Journal of Korean Society of Transportation
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• v.26 no.5
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• pp.185-194
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• 2008

The objective of this paper is to design the dynamic route guidance system(DRGS) and develop an ant algorithm based on routing mechanism for finding the multiple shortest paths within limited time in real traffic network. The proposed ant algorithm finds a collection of paths between source and destination considering turn-restrictions, U-turn, and P-turn until an acceptable solution is reached. This method can consider traffic constraints easily comparing to the conventional shortest paths algorithms.

• Fisheries and Aquatic Sciences
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• v.8 no.1
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• pp.1-5
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• 2005

Cell growth of the marine microalga Tetraselmis suecica was regulated by the addition of seaweed extracts in its culture medium. Of 26 species of seaweed tested, water-soluble extracts from Monostroma nitidum and Pachymeniopsis elliptica and methanol-soluble extract from Sargassum confilsum enhanced the growth of T suecica cells. The water extract of M. nitidum was the most effective, producing up to a 2-fold increase in cell density with the addition of 1 mg/mL of extract to the culture medium. Cell size, gross biochemical composition, fatty acids, and digestion efficiency all differed marginally between cultures of T suecica grown with and without the M. nitidum extract.

• Proceedings of the Korea Concrete Institute Conference
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• 2006.05b
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• pp.93-96
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• 2006

To investigate the properties of high flowing concrete with fly ash and crushed sand for CFT structure, many batches were performed by a trial-error method and the results were analyzed by SPSS software program. In the experiment W/B was set up as 0.25 and the variables were a substitution ratio of fly ash, a blend ratio of crushed sand and the ages of specimens (3, 7, 28 days). The results of this study are summarized as the follows; 1) The increase of the substitution ratio of fly ash, the decrease of dosage of SP and the increase of dosage of AEA due to very fine sphere particle of fly ash. 2) The increase of the blend ratio of crushed sand, the increase of dosage of S/a and water content related with viscosity. 3) Made the high flowing concrete, the increase S/a and the increase the water content.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.295-298
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• 2008

We developed a novel PVA pixel design for mobile application with excellent off-axis image quality and optical performance by introducing Active Level Shift technology and optimizing pixel structure. Our new pixel design enables better off-axis image quality without sacrificing other optical properties compared with a conventional mPVA structure.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.109-112
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• 2008

The grain size of JIC poly-Si can be varied from few tens of nanometers to the one having the larger grain size exceeding that of excimer laser crystallized (ELC) poly-Si according transmission electron microscopy. JIC poly-Si exhibits an excellent uniformity with regards to the grain size. We report here the blanket crystallization of the large area using the $2^{nd}$ generation glass substrate.

• Proceedings of the KIEE Conference
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• 2004.07d
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• pp.2317-2319
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• 2004

In many cases the systems are so complex that it is not possible to obtain reasonable models using physical laws. Also a model based on physical laws contains a number of unknown parameters even if the structure is derived from physical laws. These problems can be solved by system identification. In this paper, plate activity vibration is selected as an example for system identification. the transfer functions of this system is derived by using ARMAX based on input/output data through experiment.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.169.5-169
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• 2001

This study proposes a neural network for solving optimization problems such as the TSP (Travelling Salesman Problem), scheduling, and line balancing. The Hopfield network has been used for solving such problems, but it frequently gives abnormal solutions or non-optimal ones. Moreover, the Hopfield network takes much time especially in solving large size problems. To overcome such disadvantages, this study adopts nodes whose outputs changes with a fixed value at every evolution. The proposed network is applied to solving a TSP, finding the shortest path for visiting all the cities, each of which is visted only once. Here, the travelling path is reflected to the energy function of the network. The proposed network evolves to globally minimize the energy function, and a ...

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.710-715
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• 2001

This research is presented for optimizing the coefficients of spring and damper by impact load which is applied to a trailer when the containers are loaded up trailer. The procedure utilize the condition that two containers, initial velocity of container, initial height of container and maximum of suspension stroke. The coefficients of spring and damper are calculated numerically through Newmark method uses finite difference expansions. The procedure of calculation is applied by one DOFs of mass-spring-damper system. The coefficients of spring and damper have large value as increase of height or decrease of stroke. The result of calculation is investigated and is used AGV design.

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.878-884
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• 2001

IGCC(Integrated Gasification Combined Cycle) power plant are becoming more attractive because of fuel flexibility and low emission. In this study, performances are evaluated when the low caloric value syngas fuels producted in gasification process is used a gas turbine originally designed naturel gas fuel. Using GateCycle computational thermal analysis model, performances of GE 7FA gas turbine are predicted for using four types of syngas. Also, off design performance is presented for firing syngas fuel in the gas turbine.