• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.881-882
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• 2006

According as society looks graying trend gradually, more shaped system that can achieve measuring health-state of old people more harmoniously construction required in field of old people's welfare and medical treatment. Health-state is measured by two methods of contact and non-contact. The first, for example measurement of blood pressure or electrocardiogram, requires that measuring equipments are attached on human body but the second, for example X-Ray or MRI, is not. But both of methods are have some of defect, for example attaching equipments, needing of the special equipments or the necessary time, etc. Therefore desirable method of monitoring system must have minimum interrupt about daily life. This study suggest the system that can monitor the user, especially old people's outward aging and health-state by use the PAN TILTER and CCD camera.

• Journal of the Korean Society of Safety
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• v.38 no.6
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• pp.1-8
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• 2023

The health state of the oil transformer is evaluated by the age of use and the state of internal defects. Mineral Oil, used as an insulator for oil transformers, creates specific gases and compounds through chemical reactions caused by heat, moisture, and partial discharge inside the transformer. It is possible to determine the aging and defect of the transformer through these gases and compounds. So, it is an important indicator to evaluate the health of a transformer. In this study, factors for assessing the health of transformers were hierarchically categorized, and key factors for each hierarchy were selected for design weighting. These weights were determined through surveys conducted with experts in the fields of transformer design, operation, and quality. For the health of a transformer, defect-related factors are approximately three times more important than factors related to aging. Additionally, defect-related factors showed a higher weighting for gases generated at high temperatures. Furthermore, Furan was determined to have a high weight, directly associated with insulating paper aging. Based on these findings, a health index was proposed, and a comparative analysis was conducted by categorizing 40 operational transformers into normal and comparison groups to evaluate and validate it.

• Toxicological Research
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• v.19 no.3
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• pp.161-172
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• 2003

Explanted mammalian cells perform a limited number of cell division in vitro and than are arrested in a state known as replicative senescence. Such cells are irreversibly blocked, mostly in the G1 phase of cell cycle, and are no longer sensitive to growth factor stimulation. Thus replicative senescence is defined as a permanent and irreversible loss of replicative potential of cells. For this characteristic, replicative senescence seems to evolve to protect mammalian organism from cancer. However, senescence also contributes to aging. It seems to decrease with age of the cell donor and, as a form of cell senescence, is thought to underlie the aging process. Extensive evidence supports the idea that progressive telomere loss contributes to the phenomenon of cell senescence. Telomeres are repetitive structures of the sequence (TTAGGG)n at the ends of linear chromosomes. It has been shown that the average length of telomere repeats in human somatic cells decreases by 30∼200 bp with each cell division. It is generally believed that when telomeres reach a critical length, a signal is activated to initiate the senescent program. This has given rise to the hypothesis that telomeres act as mitotic clocks to regulate lifespan. One proposes that cumulative oxidative stress, mainly reactive oxygen species generated from mitochondria, may mainly cause telomere shortening, accelerating aging. Here, the biological importance and mechanism of replicative senescence were briefly reviewed. Also it was summarized that how oxidative stress affects replicative senescence and telomere shortening.

• Journal of Korean Traditional Oncology
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• v.20 no.1
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• pp.81-88
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• 2015

Generally, normal cells synthesize adenosine triphosphate (ATP) through oxidative phosphorylation in the mitochondria. However, they produce ATP through lactic acid fermentation on hypoxic condition. Interestingly, many cancer cells rely on aerobic glycolysis for ATP generation instead of mitochondrial oxidative phosphorylation, which is termed as "Warburg effect". According to results from recent researches on differences of cancer cell metabolism from normal cell metabolism and because chemotherapy to suppress rapidly growing cells, as a side effect of cancer treatment, can still target healthy cells, there is merit in the development of small-molecule inhibitors targeting metabolic enzymes such as pyruvate dehydrogenase kinase (PDHK), lactate dehydrogenase (LDH) and monocarboxylate transporter (MCT). For new anticancer therapy, in this review, we show recent advances in study on cancer cell metabolism and molecules targeting metabolic enzymes which are importantly associated with cancer metabolism for cancer therapy. Furthermore, we would also like to emphasize the necessity of development of molecules targeting metabolic enzymes using herbal medicines and their constituents for anticancer drugs.

• Journal of the Korean Society of Clothing and Textiles
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• v.35 no.6
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• pp.678-686
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• 2011

Older people have increased interest and involvement in controlling their aging body through physical exercise and dieting. This study examined the relationship between body image and the participation of older people in exercise and dieting. Two measures of body image (appearance attitude and appearance orientation) were used to study their relationships to participation in exercise and dieting among older people. Data were collected via a mail survey of older married couples residing in three U.S. metropolitan areas of Florida. A total of 94 couples who were 60 years older participated in this study. Multiple regression was run separately for men and women. The results indicated that for both men and women, appearance attitude was inversely related to dieting and positively related with exercise (even though the relationship with exercise was weak for men). Appearance orientation was not significantly related to exercise or dieting for both men and women. A new scale development on body image for an aging population was suggested. Various activities performed by aging people to manage their aging body and appearance need to be studied as related to physical and psychological well-being that includes body image.

• Asian Journal of Atmospheric Environment
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• v.4 no.2
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• pp.106-114
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• 2010

By the application of novel double detector system of micro-PIXE that can detect light elements (Z<14), we made an attempt to provide a thorough discussion on the aging processes of Asian dust (hereafter called "AD") particle by reaction with sea-slat. The elemental spectra and maps obtained from the microbeam radiation of micro-PIXE to individual AD particles were useful for fractionating AD particles into both internally and externally mixed particles. A spatial distribution of elements in a minute domain of single particle obtained by scanning the microbeam irradiation enabled us not only to estimate the chemical mixing state of individual AD particles but also to presume their aging processes in both ambient air and cloud. By calculating the normalized micro-PIXE net count of elements, it was possible to classify individual AD particles into three distinct groups (i.e., (1) Aging type 1: AD particle coated by the gaseous Cl evaporated by the reaction between artificial acids and sea salt; (2) Aging type 2: AD particle mixed with sea salt but no additional reaction with artificial acids; and (3) Non-aged type) A relatively high transformation rate (63.3-75.9%) was shown in large particles (greater than $5.1\;{\mu}m$ in diameter).

• Journal of the Ergonomics Society of Korea
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• v.29 no.4
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• pp.505-511
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• 2010

The purpose of this study was to show the occurrences of musculoskeletal disease in aging society and basic information on developments of a systematic prevention program and proposed management measures needed to prevent the disease. The Korea Occupational Safety & Health Agency has analyzed cases of industrial accidents that cause musculoskeletal disease, from 1998 to 2007. They found 30,439 people suffering from the disease during those ten years. This information is from the Ministry of Labor's industrial accident analysis and the industrial accident survey from the Korea Occupational Safety & Health Agency. The data was analyzed by age and industrial classification. In Korea, according to the studies on aging society, the occurrence of musculoskeletal disease in elderly employee's have increased, so prevention programs are needed. Psychological, mental and cognitive programs are needed, as well as other prevention programs to ensure health in old age. In this study, we were able to see the state of musculoskeletal disease in aging society and the countermeasures to prevent the disease, such as a universal design, guarantees, and recuperation services. Later, we found that studying the various elderly patients would be of great help to us.

• Earthquakes and Structures
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• v.3 no.5
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• pp.649-673
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• 2012

Recent studies have highlighted the importance of accounting for aging and deterioration of bridges when estimating their seismic vulnerability. Effects of structural degradation of multiple bridge components, variations in bridge geometry, and comparison of different environmental exposure conditions have traditionally been ignored in the development of seismic fragility curves for aging concrete highway bridges. This study focuses on the degradation of multiple bridge components of a geometrically varying bridge class, as opposed to a single bridge sample, to arrive at time-dependent seismic bridge fragility curves. The effects of different exposure conditions are also explored to assess the impact of severity of the environment on bridge seismic vulnerability. The proposed methodology is demonstrated on a representative class of aging multi-span reinforced concrete girder bridges typical of the Central and Southeastern United States. The results reveal the importance of considering multiple deterioration mechanisms, including the significance of degrading elastomeric bearings along with the corroding reinforced concrete columns, in fragility modeling of aging bridge classes. Additionally, assessment of the relative severity of exposure to marine atmospheric, marine sea-splash and deicing salts, and shows 5%, 9% and 44% reduction, respectively, in the median value bridge fragility for the complete damage state relative to the as-built pristine structure.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2010.04a
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• pp.232-236
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• 2010

• Proceedings of the KWS Conference
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• 2001.05a
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• pp.271-272
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• 2001