• Title/Summary/Keyword: Aging Resistance

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Effects of exercise training on the biochemical pathways associated with sarcopenia

  • Seo, Dae Yun;Hwang, Boo Geun
    • Korean Journal of Exercise Nutrition
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    • v.24 no.3
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    • pp.32-38
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    • 2020
  • [Purpose] Sarcopenia is considered one of the major causes of disability in the elderly population and is highly associated with aging. Exercise is an essential strategy for improving muscle health while aging and involves multiple metabolic and transcriptional adaptations. Although the beneficial effects of exercise modalities on skeletal muscle structure and function in aging are well recognized, the exact cellular and molecular mechanisms underlying the influence of exercise have not been fully elucidated. [Methods] We summarize the biochemical pathways involved in the progression and pathogenesis of sarcopenia and describe the beneficial effects of exercise training on the relevant signaling pathways associated with sarcopenia. [Results] This study briefly introduces current knowledge on the signaling pathways involved in the development of sarcopenia, effects of aerobic exercise on mitochondria-related parameters and mitochondrial function, and role of resistance exercise in the regulation of muscle protein synthesis against sarcopenia. [Conclusion] This review suggested that the beneficial effects of exercise are still under-explored, and accelerated research will help develop better modalities for the prevention, management, and treatment of sarcopenia.

Performance Evaluation of Polymer Insulator using Tracking Wheel and Multi-Aging Test (트래킹 휠과 복합열화시험에 의한 폴리머 애자의 성능 평가)

  • 조한구;안명상;한세원;허종철;이운용
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.07a
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    • pp.119-122
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    • 2000
  • Recently polymer insulators are being used for outdoor high voltage applications. Polymer insulators for transmission line have significant advantages over porcelain and glass insulators, especially for ultra-high voltage transmission lines. Their advantages are light weight, vandalism resistance and hydrophobicity. Polymer insulators are a relatively new technology, but their expected life is still unknown. Therefore these estimating technique are very important. Their life time is related to weathering and operating condition. Multi-aging test is requested because aging factor is occurred by multi-aging than unique aging. The aging test about polymer insulators have mainly carried out by IEC 61109. This paper presents multi-stress chamber experiments and tracking wheel test to examine the tracking and erosion performance of polymer insulator for transmission. Multi-stress testing is able to demonstrate deficiencies of polymer insulator materials and designs, including the nature of interfaces in insulation design. We have investigated IEC 61109 Annex C (5000h aging test) and CEA tracking wheel test as test methods of artificial accelerated aging. The aging degree of polymer insulator is estimated by leakage current, measurement of hydrophobicity degree, damage conditions of insulator surface, withstand voltage test etc.

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A Study on the Oxidation Resistance of Aluminum Cast Iron by Aluminum Content (알루미늄 함량에 따른 알루미늄 주철의 내산화성에 관한 연구)

  • Kim, Dong-Hyuk
    • Journal of Korea Foundry Society
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    • v.40 no.6
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    • pp.135-145
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    • 2020
  • Aluminum cast iron has excellent oxidation resistance, sulfurization resistance, and corrosion resistance. However, the ductility at room temperature is insufficient, and at temperatures above 600?, the strength drops sharply and practicality is limited. In the case of heat-resistant cast iron, high-temperature materials containing Cr and Ni account for 30 to 50% or more. However, these high-temperature materials are expensive. Aluminum heat-resistant cast iron is considered as a substitute for expensive heat-resistant materials. Oxidation due to the aging temperature and holding time conditions increases more in 0 wt.% Al-cast iron than in 2 and 4 wt.% Al-cast iron according to oxidized weight and gravimetric oxide layer thickness measurements. As a result of observing the cross-section of the oxide layer, it was found to contain 0 wt.% of Al-cast iron silicon oxide-containing SiO2 or Fe2SiO4 oxide film. In cast iron containing aluminum, the thickness of the internal oxide layer due to aluminum increases as the aging temperature and retention time increase, and the amount of the iron oxide layer generated on the surface decreases.

Study on Property Modification with Kind and Additive Amount of Plasticizer in the Manufacture of Compounds for Cable Sheath (전선피복용 컴파운드의 제조에서 가소제의 종류와 첨가량에 따른 물성 변화 연구)

  • Li, Xiangxu;Lee, Sang Bong;Cho, Ur Ryong
    • Journal of the Semiconductor & Display Technology
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    • v.18 no.2
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    • pp.11-16
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    • 2019
  • The four different polymer compounds were manufactured with the two kinds of plasticizers [(di-2-ethylhexyl sebacate(DOS), and di-2-butyl sebacate(DBS)] and two different additive amounts(18, 26 phr) of the same plasticizer for making cable sheath for ship. Ethylene-vinylacetate, ethylene-propylene-diene-copolymer as matrix polymers and ethylene-vinylacetate grafted maleic anhydride as coupling agent were selected for compounding with fire retardant, closslinking agent, filler, and other additives besides plasticizer. The compound including DOS showed the higher ${\Delta}T$ than that including DBS at the same additive amount in the rheology test. And with increasing plasticizer, the compounds resulted in lower tensile strength and higher elongation by lubricating effect of plasticizer. DOS yielded better aging resistance and cold resistance than DBS due to the good heat resistance and low solidifying point of DOS compared to DBS.

A Study on Aging and Wear Behaviors of Al-5Mg-X(Si, Cu, Ti)/SiCp Composites Fabricated by Pressureless Infiltration Method (무가압 침투에 의하여 제조된 Al-5Mg-X(Si, Cu, Ti)/SiCp 복합재료의 시효 및 마멸특성에 관한 연구)

  • Woo, Kee-Do;Kim, Sug-Won;Na, Hong-Suk;Moon, Ho-Jung
    • Journal of Korea Foundry Society
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    • v.20 no.5
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    • pp.300-306
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    • 2000
  • The objective of this work was to investigate the effects of SiC particle size(50, 100 ${\mu}m$) and additional elements such as Si, Cu and Ti on aging behavior in Al-5Mg-X(Si,Cu,Ti)/SiCp composites fabricated by pressureless infiltration method using hardness and wear test, scanning electron microscopy(SEM) and differential scanning calorimetry(DSC). The peak aging time in Al-5Mg-X(Si, Cu, Ti)/SiCp(50, 100 ${\mu}m$) composites is shorter than Al-5Mg-0.3Si alloy.The peak aging time of 50 ${\mu}m$ SiC particle reinforced Al-5Mg-X(Si,Cu,Ti) composites is shorter than those of 100 ${\mu}m$ SiC particle reinforced of Al-5Mg-X(Si,Cu,Ti) composites. The Al-5Mg-0.3Si-0.1Cu-0.1Ti/SiCp(50 ${\mu}m$) composites aged at $180^{\circ}C$ has higher hardness and better wear resistance than any other aged composite.The aging effect is promoted by the addition of Si and Cu in Al-5Mg/SiCp composites, so the wear resistance of Al-5Mg/SiCp composites with Si and Cu elements is enhanced by the aging treatment.

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Thermal Aging Behavior of H-NBR/NBR Blend (H-NBR/NBR 블렌드의 열노화거동)

  • Choi, Won-Seok;Kim, Gun-Wan;Do, Je-Sung;Yoo, Myung-Ho;Ryu, Sung-Hun
    • Elastomers and Composites
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    • v.46 no.2
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    • pp.132-137
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    • 2011
  • In the present investigation, thermal aging behavior of H-NBR/NBR blend with various H-NBR content was investigated. Mixture of dicumyl peroxide and sulfur were used as a curing agent. The influence of the thermal aging of the H-NBR/NBR blends on the solid state properties such as tensile strength, elongation at break, hardness and abrasion resistance was investigated. Tensile strength was increased with increasing H-NBR content, while abrasion resistance was decreased. Both elongation at break and hardness were not affected by the addition of H-NBR. The properties such as hardness, tensile strength and elongation at break of the aged samples were lower than unaged samples. However, the rate of deterioration of those properties was decreased by increasing the H-NBR content, which indicated that improved thermal aging behavior was obtained by the addition of H-NBR. Abrasion loss was increased with increasing aging time, but it became less by the addition of H-NBR addition.

The Influence of Dynamic Strain Aging on Tensile and LCF Properties of Prior Cold Worked 316L Stainless Steel (냉간가공된 316L 스테인리스 강의 인장 및 저주기 피로 물성치에 미치는 동적변형시효의 영향)

  • Hong, Seong-Gu;Lee, Soon-Bok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.8
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    • pp.1398-1408
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    • 2003
  • Tensile and LCF(low cycle fatigue) tests were carried out in air at wide temperature range 20$^{\circ}C$-750$^{\circ}C$ and strain rates of 1${\times}$10$\^$-4//s-1${\times}$10$\^$-2/ to ascertain the influence of strain rate on tensile and LCF properties of prior cold worked 316L stainless steel, especially focused on the DSA(dynamic strain aging) regime. Dynamic strain aging induced the change of tensile properties such as strength and ductility in the temperature region 250$^{\circ}C$-600$^{\circ}C$ and this temperature region well coincided with the negative strain rate sensitivity regime. Cyclic stress response at all test conditions was characterized by the initial hardening during a few cycles, followed by gradual softening until final failure. Temperature and strain rate dependence on cyclic softening behavior appears to result from the change of the cyclic plastic deformation mechanism and DSA effect. The DSA regimes between tensile and LCF loading conditions in terms of the negative strain rate sensitivity were well consistent with each other. The drastic reduction in fatigue resistance at elevated temperature was observed, and it was attributed to the effects of oxidation, creep and dynamic strain aging or interactions among them. Especially, in the DSA regime, dynamic strain aging accelerated the reduction of fatigue resistance by enhancing crack initiation and propagation.

Influence of the preparation design and artificial aging on the fracture resistance of monolithic zirconia crowns

  • Mitov, Gergo;Anastassova-Yoshida, Yana;Nothdurft, Frank Phillip;See, Constantin von;Pospiech, Peter
    • The Journal of Advanced Prosthodontics
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    • v.8 no.1
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    • pp.30-36
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    • 2016
  • PURPOSE. The aim of this study was to evaluate the fracture resistance and fracture behavior of monolithic zirconia crowns in accordance with the preparation design and aging simulation method. MATERIALS AND METHODS. An upper first molar was prepared sequentially with three different preparation designs: shoulderless preparation, 0.4 mm chamfer and 0.8 mm chamfer preparation. For each preparation design, 30 monolithic zirconia crowns were fabricated. After cementation on Cr-Co alloy dies, the following artificial aging procedures were performed: (1) thermal cycling and mechanical loading (TCML): 5000 cycles of thermal cycling $5^{\circ}C-55^{\circ}C$ and chewing simulation (1,200,000 cycles, 50 N); (2) Low Temperature Degradation simulation (LTD): autoclave treatment at $137^{\circ}C$, 2 bar for 3 hours and chewing simulation; and (3) no pre-treatment (control group). After artificial aging, the crowns were loaded until fracture. RESULTS. The mean values of fracture resistance varied between 3414 N (LTD; 0.8 mm chamfer preparation) and 5712 N (control group; shoulderless preparation). Two-way ANOVA analysis showed a significantly higher fracture loads for the shoulderless preparation, whereas no difference was found between the chamfer preparations. In contrast to TCML, after LTD simulation the fracture strength of monolithic zirconia crowns decreased significantly. CONCLUSION. The monolithic crowns tested in this study showed generally high fracture load values. Preparation design and LTD simulation had a significant influence on the fracture strength of monolithic zirconia crowns.

The Evaluation of Thermal Aging Characteristics in Insulating Materials of the Pole Transformers (가속열화 방법에 의한 주상변압기 절연물의 열 열화 특성 평가)

  • 이병성;송일근;이재봉;한상옥
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.16 no.12
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    • pp.1136-1141
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    • 2003
  • The primary insulation materials used in an oil filled transformer are kraft paper, wood, porcelain and oil. Modern transformers use chemically treated paper to improve its tensile strength and resistance to aging caused by immersion in oil. But these insulation papers are mainly aged by thermal stress. Over the life time of the insulation paper and oil, it is exposed to high temperatures, oxygen and water. Its interaction with the steel of the tank and core plus the copper and aluminium of the windings will eventually cause the chemical properties of the oil to decay. High temperature have an effect on mechanical strength of cellulous paper used in the layer insulation. We made two aging cells in which insulation papers and mineral oil are conducted to test thermal properties. It is measured dielectric strength, number of acid, moisture, etc. of insulation paper and oil aged in the aging cells.

Influence of Room Temperature and Strain Aging on the COD for a Small Fatigue Crack (室溫時效 및 變形時效가 微小 疲勞크랙의 開口變位에 미치는 影響)

  • 김민건
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.19 no.2
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    • pp.402-407
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    • 1995
  • The effects of room temperature and strain aging treatment are discussed on the critical condition for the onset of growth of non-propagating cracks on 0.15% C low carbon steel, with special emphasis on the length of the critical non-propagating crack and on the crack opening displacement(COD) at the crack tip. It is found from the experimental analysis that room temperature and strain aging of a fatigue pre-cracked specimen introduced the closure of a crack tip of the pre-crack and the reduction of crack opening displacement at the wake of crack, together with an improvement in crack growth resistance of the microstructure. This may cause an increase in the endurance limit of the specimen, through the enhancement of effective stress for the onset of growth of the critical non-propagating crack.