• 한국식품영양과학회지
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• 제34권9호
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• pp.1320-1324
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• 2005

식생활에서 쉽게 접하고, 다양한 생리 활성 물질을 함유하고 있는 국산콩에 대하여 품종별로 용매 추출하여 각 추출물에 대한 혈소판 응접에 미치는 영향과 혈소판 응집을 유도하는 collagen과 thrombin에 대한 응집 억제작용을 비교하였고, isoflavone 유도체의 함량 및 검정콩 종피 추출물이 혈소판 응집억제에 미치는 효과를 연구하였다. 국산콩 품종별 용매추출물 1 mg/mL을 collagen $2 {\mu}g/mL$과 thrombin 0.1unit/mL으로 유도한 혈소판 응집반응에 메탄올보다 부탄을 추출물에서 감한 응집억제 효과가 있는 것으로 나타났다. 또한 진품콩과 검정콩의 부탄을 추출물이 collagen에 대하여 각각 $94\%$와 $95\%$의 혈소판 응집 억제율이었고 검정콩이 thrombin에서도 $95\%$의 혈소판 응집억제작용을 나타내었다. 혈소판 응집 억제율이 가장 강한 진품콩과 검정콩의 iso-flavone 함량은 진품롱의 genistein과 daidzein 함량이 검정콩의 genistein과 daidzein의 함량보다 모두 3배 가량 높았다. 배당체인 genistin의 함량은 두 품종 모두 비 배당체인 gem stein과 daidzein 함량보다 높았으며, 총 isoflavone 함량에서도 진품콩이 검정콩보다 높은 함량이었다. Isoflavone 유도체의 혈소판 응집억제작용은 collagen으로 유도한 혈소판 응집 반응에서 $200 {\mu}g/mL$농도에서 genistein>daidzein>geni-stin 순으로 각각 $97\%,\;38\%,\;13\%$로 억제되었고, thrombin으로 유도한 혈소판 응집 반응에서는 약한 억제작용을 나타내었다. 검정콩 종피에서 메탄올 및 부탄올 추출물의 혈소판응집 억제작용은 collagen에서 각각 $86\%$와 $61\%$로 나타내었고, thrombin에서도 $36\%$와 $32\%$의 응집 억제작용을 보였다. 이상의 결과에서 진품콩과 검정콩의 혈소판 응집억제작용은 총 isoflavone 함량과 관련이 있으며, isoflavone 유도체 에서 -OH group이 3개인 genistein이 -OH group이 2개인 daizein보다 혈소판 응집억제작용이 강하며, 당이 결합된 genistin 배당체의 약한 응집억제작용은 -OH group 수와 배당체의 관련성을 보여주고 있는 것으로 시사되었다.

• Journal of Ginseng Research
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• 제9권1호
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• pp.15-23
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• 1985

The study was carried out to confirm the changes of soil physico-chemical properties and population of Fusarium solani by soil managements at preplanning fields for ginseng cultivation. Soil porosity and aggregation had been significantly increased during the managements while exchangeable nitrogen content and bulk density of the soil had been decreased. Available phosphate and exchangeable potassium content, in addition, seemed to be slightly increased. And soil aggregation showed positive correlation with clay, organic matter, soil moisture, and Ca content in the soil but negative with K content. Decrease rate of NH4-N and NO3-N content after soil managements were 55% and 41% in average, respectively. And better decrease effect for NH4-N was obtained in sand loam soil whereas no effect for NO3-N with soil textures. The more ploughing seemed to result in less propagules of F solani in the soil, however there was non significant decrease in population of the pathogen after the soil management. Number of F. solani in soil was significantly less in the fields where gramineous and leguminous crops had been grown as a precrop than other crops tested. Meanwhile there was no correlation between soil texture and population of the pathogen in the soil.

• 한국경영과학회지
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• 제22권1호
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• pp.123-140
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• 1997

In this paper we consider closed flow line systems with samploing inspections. The total number of parts in the system is assumed to be N. The processings carried out of each station do not always meet the requirement of quality. Therefore, upon completion of its processing at each station, a part is inspected to determine whether the processings meet the requirement of quality or not. We assume that inspection are done on a random basis. If a part is found to be defective by an inspection, it is fed back to the apropriate station. Two different cases will be considered in this study : a three-station flow line system with infinite buffers and a two-station flow line system with finite buffers. For each case, we will develop an exact method to obtain the performance measures such as throughput, machinen utilization, average outgoing quality and manufacturing lead time. For the case of the two-station flow line system ith finite buffers, we will also develop an approximation method using a stage-aggregation technique. Then using buffers, we will also develop an approximation method using a stage-aggregation technique. Then using these results, we will try to find an optimal inspection policy which maximizes the expected net profit under a certain cost structure. Although we present the results only for the two or three station flow line system in this paper, the results obtained in this paper can be extended easily to the system which consists of more than two or three stations.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 추계학술대회 논문집 학회본부 A
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• pp.273-275
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• 1999

This paper presents a dynamic equivalencing method in large electric power system for stability analysis. This method of modeling simplified equivalents for parts of the network outside the study area is to evaluate the stability of a study area modeled in detail. Generators are closely coupled in an electrical sense tend to swing together in groups during disturbances, and this behavior can be exploited to reduce the size of the power system model. The characteristics of generators swing together are referred to as coherency Coherency groups whose generators state trajectory are similar to the other generators state trajectory in the same coherency group by a certain disturbance. In this paper, procedures for forming dynamic equivalents of control devices of coherency-based generating units are proposed and the aggregation of the control devices such as excitation system and governor-turbine system is accomplished by this method. This method can deal with the aggregation of the same type of control devices and combination of hydro and steam unit or the many types of excitation systems. etc. This method is shown to be efficient in reducing the number of control device of generating units with small error in the study group by result of case study presented latter part of this paper.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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• pp.612-615
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• 2007

Water quality modelling is an ideal tool of simulating physical, chemical and biological changes occurring in water systems. It has been utilized in a number of GIS-based water quality management and analysis applications. However, there is a need of a decision making process to translate the modelling result into an understandable form thereby implement the modelling results to the real world. This paper outlines a new water quality index called the QUAL2E's water quality index (QWQI) based on the water quality modelling using QUAL2E. The development mainly includes four steps: variable selection, sub-index development, weight assignment and sub-index aggregation. An experiment of applying the index and GIS to the Sapgyo River in Korea was implemented. Different from other water quality indices for general water uses, the index is specifically used for the simulated water quality indicators. The index can provide a simple and easy-to-understand decision support. Furthermore, interfacing with GIS, the decision analysis can be performed within a spatial environment. However, more study needs to be made in the future including the improvement of aggregation function.

• BMB Reports
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• 제38권3호
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• pp.259-265
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• 2005

Proteins must fold into their correct three-dimensional conformation in order to attain their biological function. Conversely, protein aggregation and misfolding are primary contributors to many devastating human diseases, such as prion-mediated infections, Alzheimer's disease, type II diabetes and cystic fibrosis. While the native conformation of a polypeptide is encoded within its primary amino acid sequence and is sufficient for protein folding in vitro, the situation in vivo is more complex. Inside the cell, proteins are synthesized or folded continuously; a process that is greatly assisted by molecular chaperones. Molecular chaperones re a group of structurally diverse and mechanistically distinct proteins that either promote folding or prevent the aggregation of other proteins. With our increasing understanding of the proteome, it is becoming clear that the number of proteins that can be classified as molecular chaperones is increasing steadily. Many of these proteins have novel but essential cellular functions that differ from that of more 'conventional' chaperones, such as Hsp70 and the GroE system. This review focuses on the emerging role of molecular chaperones in protein quality control, i.e. the mechanism that rids the cell of misfolded or incompletely synthesized polypeptides that otherwise would interfere with normal cellular function.

• 한국통신학회논문지
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• 제36권12A호
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• pp.984-993
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• 2011

본 논문에서는 인프라구조 기반의 애드혹 네트워크에서 노드의 효율적인 이동성 관리를 위한 방식을 제시한다. 이러한 종류의 네트워크는 자연적으로 IG를 기준으로 히는 트리 형태의 네트워크 모델을 갖게 된다. 따라서, IG에 가까운 노드가 많은 메시지를 처리하게 됨으로써 병목현상을 발생시키고 네트워크의 성능을 저하시키는데 이러한 문제는 깔때기 효과 (Funneling Effect)로 알려져 있다. 이 문제를 해결하기 위하여 주기적으로 트리를 구성하고 트리의 깊이에 따라서 기울진 시간 동기화를 수행하여 결합전송의 정도를 최적화하는 방식을 제안한다. 시뮬레이션을 통하여 깔때기 효과가 크게 개선되고 성능이 개선됨을 입증하였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제8권9호
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• pp.3034-3055
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• 2014

Wireless Sensor Networks have extensively been utilized for ambient data collection from simple linear structures to dense tiered deployments. Issues related to optimal resource allocation still persist for simplistic deployments including linear and hierarchical networks. In this work, we investigate the case of dimensioning parameters for linear and tiered wireless sensor network deployments with notion of providing extended lifetime and reliable data delivery over extensive infrastructures. We provide a single consolidated reference for selection of intrinsic sensor network parameters like number of required nodes for deployment over specified area, network operational lifetime, data aggregation requirements, energy dissipation concerns and communication channel related signal reliability. The dimensioning parameters have been analyzed in a pipeline monitoring scenario using ZigBee communication platform and subsequently referred with analytical models to ensure the dimensioning process is reflected in real world deployment with minimum resource consumption and best network connectivity. Concerns over data aggregation and routing delay minimization have been discussed with possible solutions. Finally, we propose a node placement strategy based on a dynamic programming model for achieving reliable received signals and consistent application in structural health monitoring with multi hop and long distance connectivity.

• Bulletin of the Korean Chemical Society
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• 제10권5호
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• pp.437-442
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• 1989

The cmc's of sodium dodecyl sulfate (SDS)/Triton X-100 surfactant mixtures were determined by surface tension measurement at various surfactant compositions. The cmc values were lower than those predicted from ideal mixture. The regular solution theory was applied to calculate the interaction parameter, micellar composition, and the activity coefficients of surfactants in the mixed micelle. The interaction parameter (${\beta}$) was - 2.1. The nonideality arised largely from decreased activity of SDS in the mixed micelle. The mean aggregation numbers (${\bar{n}}$) and micropolarity of hydrocarbon region of the mixed micelles were determined by luminescence probe techniques. The total aggregation number (${\bar{n}}_{SDS}+{\bar{n}}_{TX}$) in mixed micelles showed little dependency on the composition of the micelle. The apparent dielectric constant of the hydrocarbon region of the micelle vs micellar composition plot showed positive deviation from linearity. Emission and emission quenching of excited tris(2,2'-bipyridine)ruthenium(Ⅱ) cation, $(Ru(bpy)_3^{2+})$, by methylviologen ($MV^{2+}$) were also investigated in the mixed micellar solutions. The quenching rate was lowest when the mole fraction of SDS in the surfactant mixtures (${\alpha}_{SDS}$) is about 0.25 and highest at ${\alpha}_{SDS}$ = 0.85. This was explained in terms of combined effects of binding of the cations with the micelle and mobility of the bound cations on the surface of the micelles.

• 지질동맥경화학회지
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• 제7권2호
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• pp.88-97
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• 2018

The prevalence of atherothrombotic disease continues to rise, presenting an increasing number of challenges to modern society and creating interest in functional foods. Platelet activation, adhesion, and aggregation at vascular endothelial disruption sites are key events in atherothrombotic disease. Physiological challenges such as hyperlipidemia, obesity, and cigarette smoking are associated with vascular changes underlying platelet aggregation and inflammatory processes. However, it is difficult to determine the beneficial response of functional foods in healthy subjects. To address this problem, challenge models and high-risk models related to smokers, obesity, and dyslipidemia are proposed as sensitive measures to evaluate the effects of functional foods in healthy subjects. In this review, we construct a model to evaluate the effects of functional food such as natural products on blood flow based on a human intervention study.