Journal of Lipid and Atherosclerosis (지질동맥경화학회지)

The Korean Society of Lipid and Atherosclerosis (한국지질동맥경화학회)
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The Model for Evaluation on Blood Flow of Functional Food in Human Intervention Study

인체에서 식품의 혈행 개선 효능 평가 모델

  • Lim, Yeni (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Kwon, Oran (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Kim, Ji Yeon (Department of Food Science and Technology, Seoul National University of Science and Technology)
  • 임예니 (이화여자대학교 식품영양학과) ;
  • 권오란 (이화여자대학교 식품영양학과) ;
  • 김지연 (서울과학기술대학교 식품공학과)
  • Received : 2018.11.09
  • Accepted : 2018.12.18
  • Published : 2018.12.31
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Abstract

The prevalence of atherothrombotic disease continues to rise, presenting an increasing number of challenges to modern society and creating interest in functional foods. Platelet activation, adhesion, and aggregation at vascular endothelial disruption sites are key events in atherothrombotic disease. Physiological challenges such as hyperlipidemia, obesity, and cigarette smoking are associated with vascular changes underlying platelet aggregation and inflammatory processes. However, it is difficult to determine the beneficial response of functional foods in healthy subjects. To address this problem, challenge models and high-risk models related to smokers, obesity, and dyslipidemia are proposed as sensitive measures to evaluate the effects of functional foods in healthy subjects. In this review, we construct a model to evaluate the effects of functional food such as natural products on blood flow based on a human intervention study.

Keywords

Acknowledgement

Supported by : National Research Foundation of Korea

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