• Title/Summary/Keyword: Age-Segregation

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Gut Microbiota Community and Its Assembly Associated with Age and Diet in Chinese Centenarians

  • Wang, Fang;Yu, Ting;Huang, Guohong;Cai, Da;Liang, Xiaolin;Su, Haiyan;Zhu, Zhenjun;Li, Danlei;Yang, Yang;Shen, Peihong;Mao, Ruifeng;Yu, Lian;Zhao, Mouming;Li, Quanyang
    • Journal of Microbiology and Biotechnology
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    • v.25 no.8
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    • pp.1195-1204
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    • 2015
  • Increasing evidence suggests that gut microbiota underpin the development of health and longevity. However, our understanding of what influences the composition of this community of the longevous has not been adequately described. Therefore, illumina sequencing analysis was performed on the gut microbiota of centenarians (aged 100-108 years; RC) and younger elderlies (aged 85-99 years; RE) living in Bama County, Guangxi, China and the elderlies (aged 80-92 years; CE) living in Nanning City, Guangxi, China. In addition, their diet was monitored using a semiquantitative dietary questionary (FFQ 23). The results revealed the abundance of Roseburia and Escherichia was significantly greater, whereas that of Lactobacillus, Faecalibacterium, Parabacteroides, Butyricimonas, Coprococcus, Megamonas, Mitsuokella, Sutterella, and Akkermansia was significantly less in centenarians at the genus level. Both clustering analysis and UniFraq distance analysis showed structural segregation with age and diet among the three populations. Using partial least square discriminate analysis and redundancy analysis, we identified 33 and 34 operational taxonomic units (OTUs) as key OTUs that were significantly associated with age and diet, respectively. Age-related OTUs were characterized as Ruminococcaceae, Clostridiaceae, and Lachnospiraceae, and the former two were increased in the centenarians; diet-related OTUs were classified as Bacteroidales, Lachnospiraceae, and Ruminococcaceae. The former two were deceased, whereas the later one was increased, in the high-fiber diet. The age and high-fiber diet were concomitant with changes in the gut microbiota of centenarians, suggesting that age and high-fiber diet can establish a new structurally balanced architecture of gut microbiota that may benefit the health of centenarians.

Application of Fuller's ideal curve and error function to making high performance concrete using rice husk ash

  • Hwang, Chao-Lung;Bui, Le Anh-Tuan;Chen, Chun-Tsun
    • Computers and Concrete
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    • v.10 no.6
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    • pp.631-647
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    • 2012
  • This paper focuses on the application of Fuller's ideal gradation curve to theoretically design blended ratio of all solid materials of high performance concrete (HPC), with the aid of error function, and then to study the effect of rice husk ash (RHA) on the performance of HPC. The residual RHA, generated when burning rice husk pellets at temperatures varying from 600 to $800^{\circ}C$, was collected at steam boilers in Vietnam. The properties of fresh and hardened concrete are reviewed. It is possible to obtain the RHA concrete with comparable or better properties than those of the specimen without RHA with lower cement consumption. High flowing concrete designed by the proposed method was obtained without bleeding or segregation. The application of the proposed method for HPC can save over 50% of the consumption of cement and limit the use of water. Its strength efficiency of cement in HPC is 1.4-1.9 times higher than that of the traditional method. Local standards of durability were satisfied at the age of 91 days both by concrete resistivity and ultrasonic pulse velocity.

Combined effect of mineral admixture and curing temperature on mechanical behavior and porosity of SCC

  • Djamila, Boukhelkhal;Othmane, Boukendakdji;Said, Kenai;El-Hadj, Kadri
    • Advances in concrete construction
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    • v.6 no.1
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    • pp.69-85
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    • 2018
  • In order to provide sufficient stability and resistance against bleeding and segregation during transportation and placing, mineral admixtures are often used in self-compacting concrete mixes (SCC). These fine materials also contribute to reducing the construction cost and the consumption of natural resources. Many studies have confirmed the benefits of these mineral admixtures on properties of SCC in standard curing conditions. However, there are few published reports regarding their effects at elevated curing temperatures. The main objective of this study is to investigate the effect of three different mineral admixtures namely limestone powder (LP), granulated blast furnace slag (GS) and natural pozzolana (PZ) on mechanical properties and porosity of SCC when exposed to different curing temperatures (20, 40, 60 and $80^{\circ}C$). The level of substitution of cement by mineral admixture was fixed at 15%. The results showed that increasing curing temperature causes an improvement in performance at an early age without penalizing its long-term properties. However the temperature of $40^{\circ}C$ is considered the optimal curing temperature to make economical and high performance SCC. On the other hand, GS is the most suitable mineral admixture for SCC under elevated curing temperature.

The Paleoenvironment(the LGM time) of the Western Coastal Area of the Korean Peninsula (eastern margin of the yellow sea)based on characteristic Cryoburtation Evidence from the kanweoldo Deposit Cheonsoo Bay West Coast of Korea. (천수만 간월도층의 퇴적후 변형상(cryoturbation)으로 해석되는 제4기 최후빙기의 한 반도 서해안의 고환경)

  • 박용안
    • The Korean Journal of Quaternary Research
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    • v.9 no.1
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    • pp.43-60
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    • 1995
  • The Kanweoldo Deposit in the Cheonsoo Bay western coast of Korean Peninsula is considered to be influenced by severe freezing condition under cold humid environment of the last glacial age. The evidence of severe freezing in the some upper part of the fine-grained Kanweoldo Deposit is characteristically irregular wavy la-mellar structure with the interval of 2∼8mm. In particular lamina show very compacted fabrics composed of rounded or spheroidal discrete aggregates covered by silt caps. Such laminar structure and associated micro-fabrics might owe to soil freezing such as ice segregation in lens form cryophoresis pressure from growing ice and disturbance by frost-creep. Furthermore pedogenesis of cold-humid type such as gleyzation or peseudo-gleyzation also might af-fect the kanweoldo Deposit in the priod of severe cold-humid cli-mate of the Wrm. The Kanweoldo sediment and organic remnant(16,708 B.P. with error limit of 250 years) affected by severe cryogenic activities sug-gest that the paleoclimate of Late Wrm in Korea might be so cold and humid as to engender the cryogenic structure in subaerial silty and sandy silt deposits.

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The non-shrinkage grout to use ground fly ash as admixture

  • Kim, Yoo;Chu, Yong-Sik;Seo, Sung-Kwan;Kim, Jang-ho Jay
    • Journal of Ceramic Processing Research
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    • v.19 no.6
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    • pp.509-513
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    • 2018
  • This study uses fly ash for non-shrinkage grout in order to develop strength of grout and improve its durability. We grind fly ash to the extent of $7,000cm^2/g$ and use ground fly ash and raw fly ash respectively at the proportion of 10%, 20%, 30% instead of OPC and compare the results drawn on the condition of each proportion. As a mixed material of grout, EVA and water-reducing agent is added in order to prevent bleeding and improve segregation resistance, CSA is added with a view to preventing drying shrinkage and improving early strength property. In regard to flow and flow time test for analyzing and evaluating workability, it is revealed that grouts of all mix proportions except raw fly ash 30% mix proportion satisfy all performance criteria. With regard to length change rate, grout with no admixture shows the highest shrinkage rate, but the rate is 0.0005%, extremely insignificant rate. As material age increases, compressive strength of two grouts, that is to say ground fly ash 10% and 20%-used grouts, exceed that of grout with no admixture or show high-level compressive strength.

Study on Cracking Causes and Patterns in Median Barrier and Guardrail Concrete in RC Bridge (콘크리트 교량 방호벽의 균열원인 및 패턴 분석에 대한 연구)

  • Choi, Se-Jin;Choi, Jung-Wook;Kwon, Seung-Jun
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.5
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    • pp.19-26
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    • 2014
  • Concrete guide rail and median barrier are an attached RC member, however they are vulnerable to cracking due to slip form construction and large surface of member. In this study, causes and pattern of cracking are analyzed through assessment and NDT (Non-Destructive Technique) evaluation for concrete guide rail and median barrier on highway structure. For this work, analysis on drying shrinkage and hydration heat are performed considering installation period, and plastic shrinkage is also analyzed considering their environmental conditions. From the evaluation, plastic settlement around steel location, drying/ plastic shrinkage, and aggregate segregation are inferred to be the main causes of cracking in the structures. The crack causes and patterns are schematized and techniques of crack-control are suggested. Furthermore concrete guide rail/ median barrier in the bridge on the sea are vulnerable to cracking at early age so that special attentions should be paid at the stages of material selection and construction.

SEJONG OPEN CLUSTER SURVEY (SOS). 0. TARGET SELECTION AND DATA ANALYSIS

  • Sung, Hwankyung;Lim, Beomdu;Bessell, Michael S.;Kim, Jinyoung S.;Hur, Hyeonoh;Chun, Moo-Young;Park, Byeong-Gon
    • Journal of The Korean Astronomical Society
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    • v.46 no.3
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    • pp.103-123
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    • 2013
  • Star clusters are superb astrophysical laboratories containing cospatial and coeval samples of stars with similar chemical composition. We initiate the Sejong Open cluster Survey (SOS) - a project dedicated to providing homogeneous photometry of a large number of open clusters in the SAAO Johnson-Cousins' UBV I system. To achieve our main goal, we pay much attention to the observation of standard stars in order to reproduce the SAAO standard system. Many of our targets are relatively small sparse clusters that escaped previous observations. As clusters are considered building blocks of the Galactic disk, their physical properties such as the initial mass function, the pattern of mass segregation, etc. give valuable information on the formation and evolution of the Galactic disk. The spatial distribution of young open clusters will be used to revise the local spiral arm structure of the Galaxy. In addition, the homogeneous data can also be used to test stellar evolutionary theory, especially concerning rare massive stars. In this paper we present the target selection criteria, the observational strategy for accurate photometry, and the adopted calibrations for data analysis such as color-color relations, zero-age main sequence relations, Sp - MV relations, Sp - $T_{eff}$ relations, Sp - color relations, and $T_{eff}$ - BC relations. Finally we provide some data analysis such as the determination of the reddening law, the membership selection criteria, and distance determination.

Genomic DNA Extracted from Ancient Antarctic Glacier Ice for Molecular Analyses on the Indigenous Microbial Communities

  • Lee, Sang-Hoon;Bidle, Kay;Falkowski, Paul;Marchant, David
    • Ocean and Polar Research
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    • v.27 no.2
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    • pp.205-214
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    • 2005
  • From ancient Antarctic glacier ice, we extracted total genomic DNA that was suitable for prokaryotic 16S rDNA gene cloning and sequencing, and bacterial artificial chromosome (BAC) library and end-sequencing. The ice samples were from the Dry Valley region. Age dating by $^{40}Ar/^{39}Ar$ analysis on the volcanic ashes deposited in situ indicated the ice samples are minimum 100,000-300,000 yr (sample DLE) and 8 million years (sample EME) old. Further assay proved the ice survived freeze-thaw cycles or other re-working processes. EME, which was from a small lobe of the basal Taylor glacier, is the oldest known ice on Earth. Microorganisms, preserved frozen in glacier ice and isolated from the rest of the world over a geological time scale, can provide valuable data or insight for the diversity, distribution, survival strategy, and evolutionary relationships to the extant relatives. From the 16S gene cloning study, we detected no PCR amplicons with Archaea-specific primers, however we found many phylotypes belonging to Bacteria divisions, such as Actinobacteria, Acidobacteria, Proteobacteria $({\alpha},\;{\beta},\;and\;{\gamma})$, Firmicutes, and Cytophaga-Flavobacterium-Bacteroid$. BAC cloning and sequencing revealed protein codings highly identical to phenylacetic acid degradation protein paaA, chromosome segregation ATPases, or cold shock protein B of present day bacteria. Throughput sequencing of the BAC clones is underway. Viable and culturable cells were recovered from the DLE sample, and characterized by their 16S rDNA sequences. Further investigation on the survivorship and functional genes from the past should help unveil the evolution of life on Earth, or elsewhere, if any.

Provenance and Microstructures of an Ancient Korean Bronze Dagger (한국(韓國) 세형동검(細形銅劍)의 미세구조(微細構造) 및 원료산지(原料産地) 추정(推定))

  • Choi, Ju;Do, Jung Man;Kim, Soo Chul;Kim, Sun Tae;Eom, Tae Yoon;Kim, Jung-Bae
    • Analytical Science and Technology
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    • v.5 no.2
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    • pp.191-197
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    • 1992
  • An ancient Korean bronze dagger excavated from Yongjai-ri, Iksan-kun, presumed to be manufactured in the pre-historical age, was examined by means of chemical analysis, energy dispersive spectrometry, optical and scanning electron microscopy. Also the measurement of lead isotope ratios was carried out in order to predict the site where raw materials were produced. The composition was identified as 75.3% Cu, 17.1% Sn and 6.8% Pb which was a typical composition of Korean bronze dagger. The microstructure was consisted of ${\alpha}$ and (${\alpha}+{\delta}$) eutectoid. The (${\alpha}+{\delta}$) eutectoid can be easily corroded in comparison with ${\alpha}$. The segregation was frequently observed in the interior of the sample. According to the lead isotopes ratios, raw materials have possibility to be from North China.

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Engineering Characteristics Assessment of Rapid Set Controlled Low Strength Material for Sewer Pipe Using Excavated Soil (굴착토를 활용한 속경성 유동성 채움재의 공학적 특성 평가)

  • Kim, Young-Wook;Lee, Bong-Chun;Jung, Sang-Hwa
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.450-457
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    • 2020
  • In this study, engineering characteristics such as flowability, segregation and compressive strength by age to derive fast hardening material mixing proportion using excavated soil. And based on optimal mixing proportion, field simulation experiment conducted in laboratory to examine the effectiveness of the method such as kelly ball drop test and soil penetration test for reviewing the following process. As as a result of evaluation, in case of kelly ball drop test and soil penetration test were securing the following process initiation time 3 hours after place CLSM. As results of these assessments, kelly ball drop test and soil penetration test were applicable for revewing following process in construction field besides unconfined compressive strength method.