• Journal of Environmental Science International
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• v.20 no.5
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• pp.655-665
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• 2011

Contamination of butyltin compounds (BTs), namely tributyltin (TBT), dibutyltin (DBT) and monobutyltin (MBT), was evaluated in sediments collected inside Jeju Harbor in 2001. The concentrations of BTs in surface sediments were comparable to those in other sites of domestic and foreign countries. The high correlations between BTs in surface ($r^2$ = 0.83~0.91) and core ($r^2$ = 0.70~0.79) sediments and the significant correlations between BTs concentrations and the number of incoming and outgoing vessels indicated that DBT and MBT were mainly degraded from TBT based on antifouling paints of vessels etc. and other sources, such as DBT and MBT, could be ignored. The butyltin degradation indices ([DBT] + [MBT]/[TBT]) in surface sediments were in the range of 2.2~3.6 (mean 2.7), indicating that the parent compound, TBT, was inflowed into the surface sediments a long ago, degraded and deposited. The sedimentation age of BTs contaminated core sediments could not estimated because the content of $^{210}Pb$ activity was nearly all the same and so the sedimentation rate could not obtained.

• BMB Reports
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• v.48 no.9
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• pp.525-530
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• 2015

Activation of the Wnt/β-catenin pathway plays a pathogenic role in age-related macular degeneration (AMD) and is thus a potential target for the development of therapeutics for this disease. Here, we demonstrated that Wnt5a antagonized β-catenin response transcription (CRT) induced with Wnt3a by promoting β-catenin phosphorylation at Ser33/Ser37/Thr41 and its subsequent degradation in human retinal pigment epithelial (RPE) cells. Wnt5a decreased the levels of vascular endothelial growth factor (VEGF), tumor necrosis factor-α(TNF-α), and nuclear factor-κB (NF-κB), which was up-regulated by Wnt3a. Furthermore, Wnt5a increased E-cadherin expression and decreased cell migration by down-regulating Snail expression, thereby abrogating the Wnt3a-induced epithelial-mesenchymal transition (EMT) in human RPE cells. Our findings suggest that Wnt5a suppresses the pathogenic effects of canonical Wnt signaling in human RPE cells by promoting β-catenin phosphorylation and degradation. Therefore, Wnt5a has significant therapeutic potential for the treatment of AMD. [BMB Reports 2015; 48(9): 525-530]

• Journal of the Korean Society of Safety
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• v.37 no.6
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• pp.81-88
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• 2022

It is necessary to better understand the effect of age-related degradation on the performance of reinforced concrete shear walls in nuclear power plants in order to ensure their structural safety in the event of earthquakes. Therefore, this paper studies seismic fragility of the typical shear wall in nuclear power plants under earthquake excitation Reinforced concrete shear wall is composed of wall, horizontal and vertical flanges. Due to characteristics of its geometry, it is difficult to predict the ultimate behavior of shear wall under earthquake excitation. In this study, for more realistic numerical simulation, the Latin Hyper-Cube (LHC) simulation technique was used to generate uncertain variables for the material properties of concrete shear walls. The effects of crack, characteristics of inelastic behavior of concrete, and loss of cross section were considered in the nonlinear finite element analysis. The effects of aging-related deterioration were investigated on the performance of reinforced concrete shear walls through analysis of undegraded concrete shear walls and degraded concrete shear walls. The resulting seismic fragility curves present the change of performance of concrete shear wall due to age-related degradation.

• Proceedings of the Korea Concrete Institute Conference
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• 1999.04a
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• pp.361-366
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• 1999

The purpose of this study is to evaluate the structural performance of Reinforced steel fiber concrete structures using early age concrete. Reinforced concrete structures using early age concrete are result in the degradation of structural performance due to crack, overload, unexpected vibration and impact load. Specimens, designed by the over 0.75% of steel fiber incorporated, were showed the ductile behavior and failed slowly with flexure and flexure-shear. Increasing the percent of steel fiber incorporated(0.25~2.0%), the ultimate shear stress of each specimen were increased 12~40% than that of specimen SSS.

• Journal of the Korea institute for structural maintenance and inspection
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• v.3 no.3
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• pp.129-137
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• 1999

Reinforced concrete structures using early age concrete were result in the degradation of structural performance due to crack, overload, unexpected vibration and impact load. It demands urgently that reinforced concrete structure using early age concrete should be improved the serviceability and structural performance with the application of new fiber materials. Therefore specimens, designed by the test varibles, such as with or without stirrup and percent of steel fiber incorporated, were constructed and tested to evaluate and develop the structural performance of reinforced steel fiber concrete beam. Based on the test results reported in this study, the following conclusions are made. Specimens, designed by the over 0.75% of steel fiber incorporated, were showed the ductile behavior and failed slowly with flexure and flexure-shear. Comparing with the load-displacement relationship of specimen BSS, designed by the recommendations of the Ministry of Construction and Transportation, reinforced steel fiber concrete beam using early age concrete, over 0.75% of steel fiber incorporated, gets enough load carrying capacity and ductility. Increasing the percent of steel fiber incorporated(0.25~2.0%), the ultimate shear stress of each specimen were increased 12~40% than that of control specimen SSS.

• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.11 no.1
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• pp.99-105
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• 1997

In the paper, aging of insulating oil in pole transformer has been studied by performing accelerated thermal aging test. Dissolved gases were extracted by air bubbling method. Concentration of dissolved gases were modified by extraction ratio of each gases in insulating oil. Aging of insulating materials were proceeded by thermal degradation and oxidation reaction. Both of the reactions followed zeroch order kinetics. Formation rate equations for hydrocarbons, carbon oxides, and hydrogen were derived. It was conformed by gas analysis and UV-Visible spectrophotometric method that iron core and copper coil in pole transformer act as catalyst during the aging process.

• Computers and Concrete
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• v.20 no.5
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• pp.529-537
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• 2017

Excessively elevated temperature can lead to cracks in prestressed concrete (PC) continuous bridge with box girder on the pier top at cement hydration age. This paper presents a case study for evaluating the behavior of PC box girder during the early hydration age using a two-stage computational model, in the form of computer program ANSYS, namely, 3-D temperature evaluation and determination of mechanical response in PC box girders. A numerical model considering time-dependent wind speed and ambient temperature in ANSYS for tracing the thermal and mechanical response of box girder is developed. The predicted results were compared to show good agreement with the measured data from the PC box girder of the Zhaoshi Bridge in China. Then, based on the validated numerical model three parameters were incorporated to analyze the evolution of the temperature and stress within box girder caused by cement hydration heat. The results of case study indicate that the wind speed can change the degradation history of temperature and stress and reduce peak value of them. The initial casting temperature of concrete is the most significant parameter which controls cracking of PC box girder on pier top at cement hydration age. Increasing the curing temperature is detrimental to prevent cracking.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.7078-7088
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• 2015

This study examined effects of health behaviors and sleep related factor on cognitive function in the elderly hypertensive patients. Data were collected through a face to face interview survey with structured questionnaire form 140 elderly with hypertension ($age{\geq}65years$) from February 5 to May 1, 2013. Research instruments included Pittsburgh Sleep Quality Index(PSQI), Epworth Sleepiness Scale(ESS) and Korean version the Mini-Mental State Examination(MMSE-K). Cognitive function was negatively related to degradation in quality of sleep(r=-.29, p<.001). Sleep duration were negatively related to body mass index(r=-.18, p=.032) and degradation in quality of sleep(r=-.59, p<.001). Sleep duration was positively related to daytime sleepiness(r=.22, p=.008). Hierarchical multiple regression showed that age, education levels and living arrangement were associated with cognitive function(F=8.56, p<.001, Adjusted $R^2=.14$). After controlling for demographic characteristics and health behaviors, degradation in quality of sleep(${\beta}=-.27$, p=.008) was identified as significant predictors of cognitive function. This final model explained 17.0% of the cognitive function in the elderly hypertensive patients(F=4.09, p<.001). Therefore, as a strategy improving cognitive function of the elderly with hypertension, therapeutic intervention should be developed to improve quality of sleep considering age, education levels and living arrangement.

• Transactions of the Korean Society of Automotive Engineers
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• v.10 no.1
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• pp.45-50
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• 2002

Use of a phenomenological model, developed far prediction of catalytic deactivation, is demonstrated in comparing harshness of different driving cycles that are currently used to rapidly age catalytic converters on engine test benches. The model shows that seemingly equivalent driving cycles cause the catalytic converters to reach significantly different levels of deactivation. The comparison of the model prediction with the limited vehicle data seems encouraging despite the simplicity of the model at the current stage of its infancy.

• Journal of Environmental Science International
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• v.12 no.1
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• pp.1-14
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• 2003

This research attempts to describe and explain the development of Korean environmental movement. It finds that the emergence of Korean environmental movement was constrained by the authoritarian nature of Korean politics. In 1970s, environmental movements were primitive and were not organized ones. With the wake of democratization in the 1980s, Korean environmental movement began to get some momentum. And in the 1990s, environmental movement to save clean water has achieved some success in certain areas. However, the emphasis on the growth of local economy in the age of local autonomy system has brought heavy degradation of local environment. The coming of the phenomena of Globalization and Cyber-Age has brought positive effects on Korean environmental movement.