• Title/Summary/Keyword: Advanced development

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다원계 Zr합금에서 Sn첨가가 미세조직과 부식특성에 미치는 영향 (Effects of Tin Addition on Microstructure and Corrosion of Zr-based Alloys)

  • 김종성;박상윤;이명호;정용환;정연호
    • 한국재료학회지
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    • 제9권10호
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    • pp.978-984
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    • 1999
  • ZrNbFeCu-xSn 합금을 진공 아크 용해법으로 제조하여 $360^{\circ}C$의 물, $400^{\circ}C$의 수증기 및 36$0^{\circ}C$의 70ppm LiOH 분위기에서 부식실험을 실시하였으며, 시편의 미세구조는 광학현미경, SEM 및 TEM으로 관찰하였다. 36$0^{\circ}C$에서 210일까지 부식 실험한 결과 대부분의 합금이 천이 전 영역에서의 부식거동을 보였다. $400^{\circ}C$ 경우, 초기에는$ 360^{\circ}C$에서의 부식거동과 비슷한 경향을 보였으나 80일 이후부터는 천이현상이 발생하여 부식속도가 급격히 증가하는 경향을 나타내었는데, Sn량이 많을수록 보다 빠른 시간에 천이현상이 발생했다. LiOH 용액에서는 전반적으로 $400^{\circ}C$에서 보다 더 늦은 시간에 천이현상이 발생했다. 석출물은 Zr(Fe,Cu)$_2$나Zr(Fe,Cu)$_3$로 추정되는 성분을 가지지만, Sn의 증가에 따라 석출물의 조성이나 크기는 거의 변화가 없는 것으로 관찰되었다.

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드론 기반 자기 이상 탐지를 이용한 해양에서의 강자성 표적 탐지 (Ferromagnetic Target Detection in the Ocean Using Drone-based Magnetic Anomaly Detection)

  • 임신혁;김동규;윤지훈;방은석;오석민;김보나;심규민;이상경
    • 한국군사과학기술학회지
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    • 제27권3호
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    • pp.338-345
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    • 2024
  • Magnetic anomaly signals from the ferromagnetic targets such as ships in the sea are measured by drone-based magnetic anomaly detection. A quantum magnetometer is suspended from the drone by 4 strings. Flight altitude and speed of drone are 100 m and 5 m/s, respectively. We obtain magnetic anomaly signals of few nT from the ships clearly. We analyze the signal characteristics by the ferromagnetic target through simulation using COMSOL multiphysics.

항원 특이적 단일 기억 B 세포 분리를 이용한 신종 바이러스 대응 신속 항체 플랫폼 개발 (Development of Rapid Antibody-based Therapeutic Platform Correspondence for New Viruses Using Antigen-specific Single Cell Memory B Cell Sorting Technology)

  • 석지윤;정수한;한예지;박아름;김정은;송영조;유치호;윤형석;구세훈;이승호;이용한;허경행;최웅
    • 한국군사과학기술학회지
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    • 제27권1호
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    • pp.116-125
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    • 2024
  • The COVID-19 pandemic is not over despite the emergency use authorization as can see recent COVID-19 daily confirmed cases. The viruses are not only difficult to diagnose and treat due to random mutations, but also pose threat human being because they have the potential to be exploited as biochemical weapons by genetic manipulation. Therefore, it is inevitable to the rapid antibody-based therapeutic platform to quickly respond to future pandemics by new/re-emerging viruses. Although numerous researches have been conducted for the fast development of antibody-based therapeutics, it is sometimes hard to respond rapidly to new viruses because of complicated expression or purification processes for antibody production. In this study, a novel rapid antibody-based therapeutic platform using single B cell sorting method and mRNA-antibody. High immunogenicity was caused to produce antibodies in vivo through mRNA-antigen inoculation. Subsequently, antigen-specific antibody candidates were selected and obtained using isolation of B cells containing antibody at the single cell level. Using the antibody-based therapeutic platform system in this study, it was confirmed that novel antigen-specific antibodies could be obtained in about 40 days, and suggested that the possibility of rapid response to new variant viruses.

A Study on Improvement and Degradation of Si/SiO2 Interface Property for Gate Oxide with TiN Metal Gate

  • Lee, Byung-Hyun;Kim, Yong-Il;Kim, Bong-Soo;Woo, Dong-Soo;Park, Yong-Jik;Park, Dong-Gun;Lee, Si-Hyung;Rho, Yong-Han
    • Transactions on Electrical and Electronic Materials
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    • 제9권1호
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    • pp.6-11
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    • 2008
  • In this study, we investigated effects of hydrogen annealing (HA) and plasma nitridation (PN) applied in order to improve $Si/SiO_2$ interface characteristics of TiN metal gate. In result, HA and PN showed a positive effect decreasing number of interface state $(N_{it})$ respectively. After FN stress for verifying reliability, however, we identified rapid increase of $N_{it}$ for TiN gate with HA, which is attributed to hydrogen related to a change of $Si/SiO_2$ interface characteristic. In contrast to HA, PN showed an improved Nit and gate oxide leakage characteristic due to several possible effects, such as blocking of Chlorine (Cl) diffusion and prevention of thermal reaction between TiN and $SiO_2$.

독성을 제거한 재조합 리신 백신 개발 및 효능평가 (Development of Non-toxic Recombinant Ricin Vaccine and Evaluation of Vaccine Efficacy)

  • 윤형석;조혜은;송동현;유치호;송영조;허경행
    • 한국군사과학기술학회지
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    • 제27권2호
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    • pp.304-310
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    • 2024
  • Ricin is a highly toxic protein which is produced in the seeds of the castor oil plant. Ricin toxin A chain has ribosomal RNA N-glycosylase activity that irreversibly hydrolyses the N-glycosidic bond of the adenine residue at position 4324 within the 28S rRNA. In this study, we developed non-toxic recombinant ricin vaccine(R51) in E. coli expression system, and evaluated efficacy of the R51 according to adjuvants. When the R51 was administered using aluminum hydroxide as an adjuvant, the vaccine efficacy was higher than that of TLR agonists or aluminum phosphate. Because it is time-consuming to administer the vaccine three times at three-week intervals, we investigated the survival rate and antibody titer of mice according to the change of time interval of vaccination. Interestingly, there was no difference in survival rate and antibody titer when R51 was administered at 0, 1, and 3 weeks or 0, 2, and 4 weeks compared to when administered at 0, 3, and 6 weeks. Therefore, the developed R51 vaccine is promising to protect soldiers from Ricin attack.

실용적 첨단유도법칙 개발을 위한 고려사항 (Considerations in Practical Advanced Guidance Law Development)

  • 조항주
    • 한국군사과학기술학회지
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    • 제5권1호
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    • pp.96-106
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    • 2002
  • Many modern guided weapon systems employ sophisticated target sensors as well as powerful computing systems. Due to such advanced features, they are required to achieve better guidance accuracy, and at the same time other guidance objectives for better weapon effectiveness and survivability. In this paper, we overview some of the technical considerations in such advanced guidance algorithm development, and briefly look at some related research works. More specifically, we discuss impact angle control, time-varying nature of the guidance system, time-to-go estimation, guidance loop stability, effect of autopilot lag and physical limitations in control variables, parasitic paths in guidance loops, etc. We also briefly look at some advanced concepts such as integrated guidance and control loop design, target adaptive guidance, guidance law development based on dual control concept, and terminal evasive maneuver.

Parentage Identification of 'Daebong' Grape (Vitis spp.) Using RAPD Analysis

  • Kim, Seung-Heui;Jeong, Jae-Hun;Kim, Seon-Kyu;Paek, Kee-Yoeup
    • Journal of Plant Biotechnology
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    • 제4권2호
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    • pp.67-70
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    • 2002
  • The RAPD data were used to assess genetic similarity among f grape cultivars. Of the 100 random primers tested on genomic DNA, 10 primers could be selected for Benetic analysis, and the selected primers generated a total of 115 distinct amplification fragments. A similarity matrix was constructed on the basis of the presence or absence of bands. The 7 grape cultivars analyzed with UPGMA were clustered into two groups of A and B. The similarity coefficient value of cultivars was high. The mean similarity index for all pairwise comparisons was 0.851, and ranged from 0.714 ('Rosaki' and 'Black Olympia') to 0.988 ('Kyoho' and 'Daebong'). After due consideration of differences in cultural and morphological characteristics of these two theoretically identical cultivars, it could be deduced that 'Daebong' is a bud sport of 'Kyoho' cultivar.

High extraction efficiency of photonic crystal microcavity GaN based light emitting diode

  • Cho, Min-Su;Moon, Ki-Won;Han, Hae-Wook;Yoon, Ji-Su;Jeong, Byoung-Koan;Shin, Jong-Keun;Chung, In-Jae
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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    • pp.471-472
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    • 2007
  • We have demonstrated that the light extraction efficiency of GaN based light emitting diodes (LEDs) can be significantly enhanced by using photonic crystal and microcavity (PCMC) effects. It was found that the extraction efficiency of the PCMC-LEDs is 9.5 times larger than that of the normal LEDs.

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New Liquid Crystal Photoalignment Materials Based on Photosensitive Polyimides Having Long Alkoxy Cinnamate Chains

  • Wu, Jing-Jing;Jeong, Seok-Jin;Lee, Seung-Hee;Lee, Myong-Hoon
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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    • pp.893-896
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    • 2007
  • A series of new photosensitive polyimides having long alkoxy cinnamate chains were synthesized for liquid crystal (LC) photoalignment material. The polymer after irradiating linearly polarized UV light induced homogeneous and stable LC alignment. The chemical structure of the polymeric material was characterized and their photochemical LC alignment behavior was evaluated.

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