• 제목/요약/키워드: Advanced Information

검색결과 9,013건 처리시간 0.042초

3D Bioprinted GelMA/PEGDA Hybrid Scaffold for Establishing an In Vitro Model of Melanoma

  • Duan, Jiahui;Cao, Yanyan;Shen, Zhizhong;Cheng, Yongqiang;Ma, Zhuwei;Wang, Lijing;Zhang, Yating;An, Yuchuan;Sang, Shengbo
    • Journal of Microbiology and Biotechnology
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    • 제32권4호
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    • pp.531-540
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    • 2022
  • Due to the high incidence of malignant melanoma, the establishment of in vitro models that recapitulate the tumor microenvironment is of great biological and clinical importance for tumor treatment and drug research. In this study, 3D printing technology was used to prepare GelMA/PEGDA composite scaffolds that mimic the microenvironment of human malignant melanoma cell (A375) growth and construct in vitro melanoma micro-models. The GelMA/PEGDA hybrid scaffold was tested by the mechanical property, cell live/dead assay, cell proliferation assay, cytoskeleton staining and drug loading assay. The growth of tumor cells in two- and three-dimensional culture systems and the anti-cancer effect of luteolin were evaluated using the live/dead staining method and the Cell Counting Kit-8 (CCK-8) method. The results showed a high aggregation of tumor cells on the 3D scaffold, which was suitable for long-term culture. Cytoskeleton staining and immunofluorescent protein staining were used to evaluate the degree of differentiation of tumor cells under 2D and 3D culture systems. The results indicated that 3D bioprinted scaffolds were more suitable for tumor cell expansion and differentiation, and the tumor cells were more aggressive. In addition, luteolin was time- and dose-dependent on tumor cells, and tumor cells in the 3D culture system were more resistant to the drug.

표준 8-VSB Advanced Television Standard의 개선된 RS Decoder ASIC 설계 (An Advanced ASIC Design of a RS Decoder for the 8-VSB ATV Standard)

  • 최진호;전문석
    • 한국통신학회논문지
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    • 제26권6B호
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    • pp.727-735
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    • 2001
  • 본 논문은 8-VSB Advanced Digital TV용으로 사용할 수 있도록 ATSC(Advanced Television Standard Committee)의 규약을 만족시키도록 구현한 Reed Solomon 디코더에 대하여 기술한다. 구현된 RS Decoder는 공유된 Tree 구조의 Arithmetic 블록을 사용하여 종래의 기술보다 더 효율적인 연산기 구조를 제안하였으며 빠른 에러 탐지와 정정 시간으로 인한 FIFO의 사용갯수와 Latency Time을 크게 감소시킨 개선된 구조를 제안한다. 일반적으로 2N+A만큼의 Latency Time과 FIFO 개수를 N+A 만큼으로 감소시켰다. 이 RS 디코더는 Verilog HDL로 설계되었고 Synopsys Design Compiler에 의해 합성되었다.

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Structural, electrical and optical properties of Al-doped ZnO thin films by pulsed DC magnetron sputtering

  • Ko, Hyung-Duk;Lee, Choong-Sun;Kim, Ki-Chul;Lee, Jae-Seok;Tai, Weon-Pil;Suh, Su-Jeong;Kim, Young-Sung
    • 한국결정성장학회지
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    • 제14권4호
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    • pp.145-150
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    • 2004
  • We have investigated the structural, electrical and optical properties of Al-doped ZnO (AZO) thin films grown on glass substrate by pulsed DC magnetron sputtering as functions of pulse frequency and substrate temperature. A highly c-axis oriented AZO thin film is grown in perpendicular to the substrate when pulse frequency of 30 kHz and substrate temperature of $400^{\circ}C$ was applied. Under this optimized growth condition, the resistivity of AZO thin films exhibited $7.40\times 10^{-4}\Omega \textrm{cm}$. This indicated that the decrease of film resistivity resulted from the improvement of film crystallinity. The optical transmittance spectra of the films showed a very high transmittance of 85∼90 % in the visible wavelength region and exhibited the absorption edge of about 350 nm. The results show the potential application for transparent conductivity oxide (TCO) thin films.

투명전도막을 위한 용해 처리된 단일막 탄소나노튜브 (Solution Processed Single Walled Carbon Nanotubes Transparent Conducting Films)

  • S. 마니바난;정일옥;유제황;장진;박규창
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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    • pp.45-45
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    • 2008
  • In recent years, new materials and technology has been developed using single-walled carbon nanotubes (SWCNTs) as an alternative to indium tin oxide (ITO) to fulfil the requirements towards novel technological drive. These technologies offer products having a broad range of conductivity, excellent transparency, neutral color tone, good adhesion, abrasion resistance as well as mechanical robustness. In addition, SWCNTs can be solution processed to replace the sophisticated vacuum techniques at high temperatures. In the present work, transparent conducting films were fabricated from the purified SWCNTs. Dispersion of purified SWCNTs was accomplished in 1,2-dichlorobenzene without using surfactants or polymers following ultrasonic process. We achieved coating of nanotubes film on poly ether suiphone (PES) for an average sheet resistance ~110 ${\Omega}/{\Box}$ of optical transmittance 80% at 550 nm. Conventional spin coating method was followed to fabricate films from the purified and dispersed nanotubes solution. The results will be presented.

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Research on Covert Communication Technology Based on Matrix Decomposition of Digital Currency Transaction Amount

  • Lejun Zhang;Bo Zhang;Ran Guo;Zhujun Wang;Guopeng Wang;Jing Qiu;Shen Su;Yuan Liu;Guangxia Xu;Zhihong Tian;Sergey Gataullin
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제18권4호
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    • pp.1020-1041
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    • 2024
  • With the development of covert communication technologies, the number of covert communication technologies using blockchain as a carrier is increasing. However, using the transaction amount of digital currency as a carrier for covert communication has problems such as low embedding rate, large consumption of transaction amount, and easy detection. In this paper, firstly, by experimentally analyzing the distribution of bitcoin transaction amounts, we determine the most suitable range of amounts for matrix decomposition. Secondly, we design a novel matrix decomposition method that can successfully decompose a large amount matrix into two small amount matrices and utilize the elements in the small amount matrices for covert communication. Finally, we analyze the feasibility of the novel matrix decomposition method in this scheme in detail from four aspects, and verify it by experimental comparison, which proves that our scheme not only improves the embedding rate and reduces the consumption of transaction amount, but also has a certain degree of resistance to detection.