Adverse drug reactions (ADR) caused by inappropriate prescription are responsible for major socioeconomic loss. Drug-drug interactions (DDI) has been recognized as a major part of ADRs and, therefore, healthcare professionals should prevent possible DDIs to minimize preventable ADRs. This study aimed to examine DDI information in drug information references and Korea Food & Drug Administration (KFDA) drug labeling information. Drug ingredients from the formulary of Health Insurance Review and Assessment Service in Korea (HIRA) were included for the study. DDI information source used for the study were Micromedex Drugdex and Drug Information Facts (DIF) with the DDI severity level of "moderate" or more. The DDI information in KFDA drug labeling were collected and compared. Drug ingredients were classified with KFDA Drug Classification and ATC Classification of WHO for the analysis. Among the total 1,355 drug ingredients satisfying inclusion criteria, 738 ingredients involved at least one DDI, which was described in Micromedex and/or DIF. Drug Ingredients of 176 involved DDI only described in KFDA drug labeling, but not Micromedex nor DIF. Drug ingredients of 35 which DDIs were described in Micromedex or DIF did not have DDI based on KFDA drug labeling. Micromedex and DIF retrieved 7,582 and 3,071 DDIs, respectively 57.6% and 58.5% of DDIs were also described in KFDA drug labeling. Central nervous system (CNS) drugs, cardiovascular system (CVS) drugs and the antiinfectives appeared to have higher frequency of DDIs among all drug classes. The highest number of DDIs with high severity level ("contraindicated" or "major") were the DDIs of CNS drugs. The antiinfectives are the second drug group having serious DDIs. The DDI pairs of the CNS drug and the antiinfective had the highest contraindication risk (13.6%). DDI information from Micromedex and DIF were not consistent with the result that only 465 ingredients' DDIs are common in both literature (total DDI numbers were 715 vs 488, respectively). And 1,652 DDI information are common in both references among 7,582 vs 3,071 DDIs, respectively. Only 55.2% of DDI information in the database contained in the KFDA drug labeling. Prescribers and pharmacists should pay attention to the drugs for CV system, CNS and infections because of higher risk of possible DDIs compared to other drug classes. KFDA drug labeling is not likely to be recommended as a good information source for DDI due to significant inconsistency of information. Drug information providers should be aware that DDI information from different sources are not consistent and therefore multiple references should be used.
The study is to grasp the problems related to operation of Maternity clinic of public health centers in seoul and needs for public health of community in relation to consumers and providers in order to improve efficiency of community public health for mothers and children. Four pregnancy woman, who receive medical care at the maternity clinic of M public health centers in seoul and understand the purpose of this study, and one nurse who works at the were the objects of this field study. Participating observation and intensive interviews were conducted to collect data. All of them were performed as necessary from time to time since December, 1994, and not during a specific period. Through an data analysis in the order of sector analysis and classification analysis, the data were classified into specific patterns and the results are the following; 1. All of the subjects were using both private hospitals and public clinics, but managing activities prior to delivery were not carried out in accordence with theories for those activities. 2. The subjects showed two types of response to utilizing maternity clinic. they answered that the advantages of the clinic were 'short waiting time for medical treatment', 'medical treatment by female doctors' and 'economical benefit.' Meanwhile, they gave negative response to the problems of 'non-implementation of delivery' 'uncleanness and insufficient facilities', 'limited time of treatment', 'lack of expertise' and 'want of public health education for materity.' 3. Problems related to operation of maternity clinic were 'lack of experts', 'irrational facility structure' and 'absolutely lack budget'. In terms of the status of managing the subjects, 'programs only aimed at attaining the central-government-assigned objects' and 'limited management before and after delivery by non-implementing delivery' were pointed out to be problems. Regarding public health education before delivery and PR relations, 'superficial public health education for maternity' and 'absence of PR programs' were named. In planning and evaluation, 'absence of autonomous planning and evaluation by the clinic itself' was a major problem in operating the clinic. 4. 'Substantial health education and PR', 'supplementation of facilities and eqipment', 'development' and supply of demanded service by the subjects', 'implementation of autonomous programs', and 'reinforcement of supplementary education' were presented as alternatives for efficient opration of maternity clinics.
This study was aimed for bettering productivity and technical level of the dental 1 aboratory, and helping the dental technician's benefits and rights, and then endowing them some belonged atmospher and stability on their post by Improving job- satisfaction and maintaining the transferability of one's post at a proper limitation. Therefore, 320 dental technicians extracted randomly from all the technicians working at 494 dental laboratories were subjected for this study. The approach to the study was a way through some postal questionaires executed from March 29, 1988 until May 4, the same year, in which total 254 technicians answered, showing 79% resp"nserate. responserate. The data-analysis was done by a model of the dental technician's transferability from their post, as considering Mobley's(1978)-model of post-transferability, and results through the study are as follows : 1. Satisfaction at a given post showed that the married is better than the unmarried(<0.05), and the experienced is better than the inexperienced(P<0.01). 2. Age, sex, educational experience, and one's service-duration did not affect significantly to the respondent's satisfaction on their post, statistically. 3. Satisfaction at a given post differed in adccordance with given conditions of one's post, i. e.,it stowed high when the monthly payment was good(P<0.05), and when too much duty on their job was given, it was the worst as shown in an example of the next order, too much
Journal of the Economic Geographical Society of Korea
/
v.7
no.1
/
pp.45-63
/
2004
The main purpose of this article is to suggest policy implications for building innovative cluster in Korea by investigating the operating system and role of the Kanagawa Science Park (KSP) located in Kanagawa prefecture, Japan as a central network agent. The KSP established mainly by private and government partnership has played a critical role for building innovative clusters as a way in which increase national competitiveness. But they also provide variety of real service from R&D to commercialization for local firms by facilitating and coordinating networks among regional economic actors such as firms, universities and public research institutes. The regional policy as a way in which increase national competitiveness in Korea is also the establishment of innovative clusters based on regional and industrial characteristics. However, the main problem with building the innovative cluster is the reduction of policy effectiveness due to duplicated supporting and coordinating institutes and institutions established by the each central administration and local governments, aimed at facilitating networks among regional economic actors. In this context, the article suggests that there is a need to build a regional central network agent by designing an organic operating system for the effective management of each network agent in accordance with the process from R&D to commercialization, i.e. an encompassed supporting system, on the basis of benchmarking the KSP operating system in Japan.
Journal of the Korea Academia-Industrial cooperation Society
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v.17
no.1
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pp.99-110
/
2016
This study examined the factors affecting the team identification of professional baseball fans. The factors were divided into the fan factor, game factors, and other factors. For the analysis, two investigators visited stadium three times in total and a total number of 297 spectators were sampled using a convenience sampling method from three baseball teams. For the fan factor, a fan who began supporting his/her team from childhood or after childhood was used as a dummy variable. The interaction effects between the fan factor and other variables were investigated to offer a stereoscopic understanding about the role of kids marketing. In addition, three game factors and four non-game factors were analyzed. The results regarding fan variable and interaction effects were obtained. Fans from their childhood have much stronger team identification, and show interaction effects with the players. Regression analysis revealed player, promotion and fan service, price, and regional connection to have positive relations with team identification. This study is especially meaningful in a sense that it has proposed positive results regarding marketing to children, and the results will contribute to both the academic field and the industry.
Lee, Kichun;Choi, So Yun;Kim, Jae Kyeong;Ahn, Hyunchul
Journal of Intelligence and Information Systems
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v.20
no.1
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pp.1-14
/
2014
Both researchers and practitioners are showing an increased interested in interactive exhibition services. Interactive exhibition services are designed to directly respond to visitor responses in real time, so as to fully engage visitors' interest and enhance their satisfaction. In order to install an effective interactive exhibition service, it is essential to adopt intelligent technologies that enable accurate estimation of a visitor's emotional state from responses to exhibited stimulus. Studies undertaken so far have attempted to estimate the human emotional state, most of them doing so by gauging either facial expressions or audio responses. However, the most recent research suggests that, a multimodal approach that uses people's multiple responses simultaneously may lead to better estimation. Given this context, we propose a new multimodal emotional state estimation model that uses various responses including facial expressions, gestures, and movements measured by the Microsoft Kinect Sensor. In order to effectively handle a large amount of sensory data, we propose to use stratified sampling-based MRA (multiple regression analysis) as our estimation method. To validate the usefulness of the proposed model, we collected 602,599 responses and emotional state data with 274 variables from 15 people. When we applied our model to the data set, we found that our model estimated the levels of valence and arousal in the 10~15% error range. Since our proposed model is simple and stable, we expect that it will be applied not only in intelligent exhibition services, but also in other areas such as e-learning and personalized advertising.
As the Internet becomes more popular, many people use it to communicate. With the increasing number of personal homepages, blogs, and social network services, people often expose their personal information online. Although the necessity of those services cannot be denied, we should be concerned about the negative aspects such as personal information leakage. Because it is impossible to review all of the past records posted by all of the people, an automatic personal information detection method is strongly required. This study proposes a method to detect or classify online documents that contain personal information by analyzing features that are common to personal information related documents and learning that information based on the Na$\ddot{i}$ve Bayes algorithm. To select the document classification algorithm, the Na$\ddot{i}$ve Bayes classification algorithm was compared with the Vector Space classification algorithm. The result showed that Na$\ddot{i}$ve Bayes reveals more excellent precision, recall, F-measure, and accuracy than Vector Space does. However, the measurement level of the Na$\ddot{i}$ve Bayes classification algorithm is still insufficient to apply to the real world. Lewis, a learning algorithm researcher, states that it is important to improve the quality of category features while applying learning algorithms to some specific domain. He proposes a way to incrementally add features that are dependent on related documents and in a step-wise manner. In another experiment, the algorithm learns the additional dependent features thereby reducing the noise of the features. As a result, the latter experiment shows better performance in terms of measurement than the former experiment does.
Journal of the Korea Institute of Information and Communication Engineering
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v.21
no.8
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pp.1581-1588
/
2017
Recently, circulating ransomware is becoming intelligent and sophisticated through a spreading new viruses and variants, targeted spreading using social engineering attack, malvertising that circulate a large quantity of ransomware by hacking advertising server, or RaaS(Ransomware-as-a- Service), from the existing attack way that encrypt the files and demand money. In particular, it makes it difficult to track down attackers by bypassing security solutions, disabling parameter checking via file encryption, and attacking target-based ransomware with APT(Advanced Persistent Threat) attacks. For remove the threat of ransomware, various detection techniques are developed, but, it is very hard to respond to new and varietal ransomware. Accordingly, in this paper, find out a making Signature-based Detection Patterns and problems, and present a pattern automation model of ransomware detecting for responding to ransomware more actively. This study is expected to be applicable to various forms in enterprise or public security control center.
Journal of the Korea Academia-Industrial cooperation Society
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v.16
no.5
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pp.3353-3360
/
2015
This study was conducted to identify the BMI of enlisted soldiers, to understand the difference between their BMI and that of other men in their age group, and to identify the influence factors of enlisted soldiers' BMI change. The survey has been conducted self-evaluation questionnaire from 23 Feb. 2009 to 31 Mar. 2009 from 4 different forces as methods. Independent-sample T-test, chi-square test and multiple linear regression analysis were used for statistical analysis from 301 collected data. As a result of surveying enlisted soldiers' BMI, their obesity rate 18.6% was lower than 22.1% of other men in their age group. In terms of health behavior, the underweight&normal weight group(2.39) showed higher diet score than the overweight group(2.13), showing that the underweight&normal weight group ate relatively slowly, less spicy and less sweet food compared to the overweight group. The overweight group(2.25) showed lower satisfaction with their body type than the underweight&normal weight group(2.98), while the overweight group(4.01) showed a significantly higher score than the underweight&normal weight group(3.37) for weight control activity. The influence factors of BMI change were diet habit, subjective perception of body type, and weight control activity. In order to improve of enlisted soldiers' BMI, it would be necessary to improve the food service and the snack bars for interventional control of food that influence obesity, rather than personal effort, in addition, education for right body-shape perception and encouraging on weight control activity.
Journal of the Korea Academia-Industrial cooperation Society
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v.16
no.2
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pp.1318-1327
/
2015
In this study, customer service representatives in call centers, the relevance of occupational stress, and turnover intention as well as the investigation of the relevance to that of demographic characteristics, health behaviors, and job-related characteristics is carried out. In particular, the relevance of occupational stress and turnover intention was attempted to be identified. From the response to the surveys of nine hospitals and five companies, there was a total of 158 people during the investigation. The collection of data was conducted by self-administered questionnaire in the period of February 1, 2013 to June 30, 2013. As the result of study, factors related to turnover intention involved age, sleep, job demands and job autonomy as significant variables. In particular, in the relevance of occupational stress and turnover intention, it was revealed that turnover intention decreases as job autonomy increases while turnover intention increases as job demands become higher. The ratio of danger of occupational stress on turnover intention eminently increased in the group of high job demands, low job autonomy, low support of supervisor and co-worker. Therefore, it is considered that efforts for improvement of occupational stress factors are required to decrease turnover intention.
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