• Environmental Mutagens and Carcinogens
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• v.22 no.4
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• pp.243-247
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• 2002

Prolonged exercise is known to increase steady-state serum high-density lipoprotein cholesterol (HDL-cholesterol) and apolipoprotein AI(apo AI) concentrations. We investigated the effect of adaptation to endurance exercise on the association of the genetic polymorphism in the apo AI gene with these biochemical parameters. 108 male subjects were randomly selected from a group of elite athletes, and 65 male samples used as sedentary control group from Korean general population. The genetic polymorphism in the apo AI gene locus was detected by polymerase chain reaction(PCR) and DNA digestion with Msp I restriction endonuclease. The genotype frequency for the Msp I RFLP was significantly different between the elite athletes and sedentary controls(P<0.05). There were, however, no significant associations between the Msp I RFLP of the apo AI gene and the biochemical parameters in elite athletic group. Therefore, our findings indicate that the Msp I RFLP of the apo AI gene was not associated with the serum apo AI and HDL-cholesterol concentrations in Korean male elite athletes.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.44-53
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• 2023

Background: The genus Panax in the Araliaceae family has been used as traditional medicinal plants worldwide and is known to biosynthesize ginsenosides and phytosterols. However, genetic variation between Panax species has influenced their biosynthetic pathways is not fully understood. Methods: Simultaneous analysis of transcriptomes and metabolomes obtained from adventitious roots of two tetraploid species (Panax ginseng and P. quinquefolius) and two diploid species (P. notoginseng and P. vietnamensis) revealed the diversity of their metabolites and related gene expression profiles. Results: The transcriptome analysis showed that 2,3-OXIDOSQUALENE CYCLASEs (OSCs) involved in phytosterol biosynthesis are upregulated in the diploid species, while the expression of OSCs contributing to ginsenoside biosynthesis is higher in the tetraploid species. In agreement with these results, the contents of dammarenediol-type ginsenosides were higher in the tetraploid species relative to the diploid species. Conclusion: These results suggest that a whole-genome duplication event has influenced the triterpene biosynthesis pathway in tetraploid Panax species during their evolution or ecological adaptation. This study provides a basis for further efforts to explore the genetic variation of the Panax genus.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.518-524
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• 2021

The purpose of this study was to examine the correlation between academic achievement, major selection motivation, work value, and campus life adjustment of healthcare major college students. Data was collected using a structured questionnaire for 495 healthcare major college students at a four-year university located in G city. As a result of the study, Academic achievement was determined with positive correlation by major selection motivation (r=.446, p<.001), work values (r=.255, p<.001), campus life adjustment(r=.391, p<.001), Major selection motivation was positively correlated with work value (r=.354, p<.001) and campus life adjustment (r=.220, p<.001). The work value showed a positive correlation with the campus life adjustment(r=.193, p<.001). It is necessary to develop a career education program that reinforces college students' major selection motivation and their work values, and a student guidance program that improves their adaptation to college life.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.2
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• pp.43-50
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• 2010

Background and Objectives: Cardiff Acne Disability Index(CADI) is one tool used internationally to measure the quality of life of acne sufferers. There, however, is a necessity of developing Korean version of CADI, as the questionnaires of the original one are written in English, making it hard to apply for Korean patients. So as a first step, we conducted a cross-cultural translation of CADI into Korean and verification of face validity. Methods: After properly translating CADI questionnaires into Korean up to guidelines for cross-cultural adaptation of health related quality-of-life measures, we conducted a survey with 122 undergraduates to get face validity, using the translated questionnaires. Results: About the translated CADI questionnaires, 86 out of 107 undergraduates replied that they had no difficulty understanding them, while 21 offered ideas about ambiguous expressions of them. Upon further examination of two oriental doctors, two sentences were additionally modified in the translated version. Conclusions: Firstly, we created the Korean version of CADI, one of the most effective methods in the world to measure acne sufferers' quality of life, by properly translated the original version into Korean. Then we conducted a survey for face validity with the translated questionnaires and gathered opinions from those questioned. After going through some examining and correcting procedures based on the opinions, we finalized the Korean version of CADI. It will also require a follow-up verification process to prove credibility and validity of the final version of Korean CADI.

• Animal Bioscience
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• v.34 no.12
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• pp.1974-1980
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• 2021

Objective: The objective of this study was to estimate standardized ileal digestibility (SID) of amino acids (AA) in growing pigs fed diets containing increasing levels of copra meal (CM) with β-mannanase supplementation. Methods: Twenty barrows (initial body weight: 34.43±0.11 kg) surgically fitted with T-cannulas at the distal ileum were individually housed in metabolism crates. Pigs were allotted to 5 dietary treatments in a completely randomized design with 4 replicates per treatment. The dietary treatments were: i) NC, negative control, corn-soybean meal (SBM) based diet, ii) PC, positive control, basal diet + 0.10% β-mannanase supplementation (800 IU/kg), iii) CM6, PC diet with 6% CM supplementation, iv) CM12, PC diet with 12% CM supplementation, and v) CM18, PC diet with 18% CM supplementation. A nitrogen-free diet was used to estimate basal endogenous losses of AA for SID calculation. All experimental diets contained 0.5% chromic oxide as an indigestible marker. Each period consisted of a 4-d diet adaptation period and a 3-d ileal digesta collection period. Results: There were no differences in apparent ileal digestibility (AID) and SID of all AA between the NC and PC treatments except that the PC treatment had lower AID and SID of glycine than the NC treatment (p<0.05). There were linear decreases in AID and SID of lysine (p<0.05) and aspartic acid (p = 0.06; tendency) with increasing levels of CM in the diets with β-mannanase. Conclusion: The β-mannanase supplementation had no effect on AA digestibility in pigs fed the corn-SBM based diet but increasing levels of CM reduced SID of lysine and aspartic acid.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.12
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• pp.1705-1711
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• 2014

The objective of this study was to evaluate the effect of ruminally protected amino acids (RPAAs) and ruminally protected fat (RPF) supplementation on ruminal fermentation characteristics (in vitro) and milk yield and milk composition (in vivo). Fourteen mid-lactating Holstein dairy cows (mean weight $653{\pm}62.59kg$) were divided into two groups according to mean milk yield and number of days of postpartum. The cows were then fed a basal diet during adaptation (2 wk) and experimental diets during the treatment period (6 wk). Dietary treatments were i) a basal diet (control) and ii) basal diet containing 50 g of RPAAs (lysine and methionine, 3:1 ratio) and 50 g of RPF. In rumen fermentation trail (in vitro), RPAAs and RPF supplementation had no influence on the ruminal pH, dry matter digestibility, total volatile fatty acid production and ammonia-N concentration. In feeding trial (in vivo), milk yield (p<0.001), 4% fat corrected milk (p<0.05), milk fat (p<0.05), milk protein (p<0.001), and milk urea nitrogen (p<0.05) were greater in cows fed RPAAs and RPF than the corresponding values in the control group. With an index against as 0%, the rates of decrease in milk yield and milk protein were lower in RPAAs and RPF treated diet than those of basal diet group (p<0.05). In conclusion, diet supplemented with RPAAs and RPF can improve milk yield and milk composition without negatively affecting ruminal functions in Holstein dairy cows at mid-lactating.

• Korean Journal of Agricultural and Forest Meteorology
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• v.17 no.1
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• pp.1-14
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• 2015

Climate change caused by elevated greenhouse gases would affect crop production through different pathways in agricultural ecosystems. Because an agricultural ecosystem has complex interactions between societal and economical environment as well as organisms, climate, and soil, adaptation measures in response to climate change on a specific sector could cause undesirable impacts on other sectors inadvertently. An integrated system, which links individual models for components of agricultural ecosystems, would allow to take into account complex interactions existing in a given agricultural ecosystem under climate change and to derive proper adaptation measures in order to improve crop productivity. Most of models for agricultural ecosystems have been used in a separate sector, e.g., prediction of water resources or crop growth. Few of those models have been desiged to be connected to other models as a module of an integrated system. Threfore, it would be crucial to redesign and to refine individual models that have been used for simulation of individual sectors. To improve models for each sector in terms of accuracy and algorithm, it would also be needed to obtain crop growth data through construction of super-sites and satellite sites for long-term monitoring of agricultural ecosystems. It would be advantageous to design a model in a sector from abstraction and inheritance of a simple model, which would facilitate development of modules compatible to the integrated prediction system. Because agricultural production is influenced by social and economical sectors considerably, construction of an integreated system that simulates agricultural production as well as economical activities including trade and demand is merited for prediction of crop production under climate change.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.885-886
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• 2006

The purpose of this study is to develop the optimal system(AAC device), which helps a person with a profound communication disorder to communicate with other people. Therefore, this system includes the user interface enhancement that is the user adaptation mode algorithm. The symbol is made with a text and an icon which is converted into Korean. The message contiol operates scanning and adjusts rate control of row-column scanning and linear scanning. This embedded system includes voice input/output and voice recording as well suggested method that could apply optimal device access algorithm from clinical environment. Therefore, we are experting that even the current system itself will be able to improve the life quality of people who need to communicate with the help of devices.

• Journal of Food Hygiene and Safety
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• v.35 no.2
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• pp.103-108
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• 2020

Recently, consumer demand for safe but minimally processed food has rapidly increased. For this reason, many food processing industries are applying hurdle technology to enhance food safety, extend shelf life, and make foods appear minimally processed. Meanwhile, studies have shown that a treatment (stress) meant to inactivate foodborne pathogens may trigger adaptation mechanisms and could even offer cross protection against subsequent treatments. Also, certain routine farm practices such as antibiotic and herbicide use could result in the development of antibiotic-resistant pathogens. Such bacteria may be tolerant to food processing-associated stress and be more likely to remain viable in processed foods. In this review, we discuss the correlation between food processing-associated stress and antibiotic resistance. We also discuss molecular mechanisms such as the use of sigma factors, SOS response pathways and efflux pumps as means of cross protection against antimicrobial compounds and other food processing-associated stresses.

• Asian Oncology Nursing
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• v.12 no.3
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• pp.237-245
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• 2012

Purpose: The purpose of this study was to identify attributes of the concept of cancer survivorship. Methods: Walker & Avant's concept analysis framework (2005) was used to review the medical & nursing text books, medical and nursing research articles related to cancer survivorship and published from 1985 to 2011. Results: There were nine aspects of the concept of cancer survivorship: A process, liminality, uncertainty, life-changing experience, complexity, unique experience, duality of positive and negative aspects, partnership, and need for support. Antecedents of cancer survivorship were cancer diagnosis and perception as a cancer survivor. Empirical referents of cancer survivorship were survival rate, quality of life, adaptation to the survivorship experience, and health-related hardiness, social support, spirituality, and health behavior. The consequences of cancer survivorship were effects on the physical, psychosocial, spiritual and socio-economic well-being of the patients. Conclusion: This concept analysis of cancer survivorship is expected to contribute to promotion of survivorship care in the clinical field by removing conceptual ambiguity and confirming the true meaning of survivorship care.