• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.159-178
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• 1995

After acupuncture needles were inserted on apkok(LI4) and Kokchi(LI11) accupoints, physiological changes induced by the varitions of 'Qi' were measured. The body temperature and pulse frequency were fromed to be decreased observed and we presumed that the needle insertion induced some changes of Qi in meridian and this seemed to be achieved by a certain process of Qi induction. We applied EAV, nervinemeter and pulse-taking machine which is widely used as oriental medicine instruments, to the same vounteers and observed the significant variations for each apparatus in spite of partial lack of reproducibility. In this paper, we described about the physical quantity measured by the medical appartatus and how it was related to the variation of Qi The proper conditions used for good oriental medicine instruments have also been suggested.

• Journal of Biomedical Engineering Research
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• v.33 no.4
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• pp.202-206
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• 2012

In this study, we developed transdermal direct drug delivery device using micro-needle painlessly. We has fabricated micro-needle that is 130 ${\mu}m$ thickness and 250 ${\mu}m$length with 10 ${\mu}m$ spiral groove for rolling down drug. Head part of micro-needle device is composed of 20ea micro-needles, an on-off valve and a protective cap. Glass bottle for containing drug is connected to head part of micro-needle device. We examined the puncture characteristic testing using porcine skin and drug delivery testing using porcine, rat skin with Indian Ink.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.14 no.2
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• pp.146-153
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• 2001

Clinical studies were done treated 5 cases of patients with tinnitus, who were treated at Dept. of oriental Oph. & Otolaryngology in the hospital of Dongshin university, Kwhang-Ju, Korea, 1 2001-2. 2001. The results were as follows 1. Explaining of ear ringing, two patients said that it's like twittering and each others variously said that it's like sounds of wind or crisply 2. The periods of a contraction are different to 4 years from 3 days, also the periods of a treatment are different to 8 weeks from 3 days. But it can't be a definition of a treatment period because of stopping treatments according to cases 3. Headache, dizziness, bradyacusia are chief symptoms being caused with tinnitus at the same times. Besides, general body weakness and syncope can he caused with tinnitus. 4. In a treatment by acupuncture, needles arc fixed at TE-17(翹風), G-31(風池), SI-19(聽宮), G-2(聽會) and kanjenggyuk(肝正格), Sinjenggyuk(腎正格) according to patients. 5. Chengshimyunjatang(淸心蓮子湯), Mihudodyungsikjatang(미후도등식장탕) can be prescribed according to physical conditions of patients. 6. After treating to becom 'Excellent' was two occasions, to become 'Good' was two occasion and to become 'Poor' was two occasions. So $60\%$ of became better them before.

• Radiation Oncology Journal
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• v.26 no.4
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• pp.263-270
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• 2008

Purpose: This study aimed to quantitatively measure the movement of tumors in real-time and evaluate the treatment accuracy, during the treatment of a liver tumor patient, who underwent radiosurgery with a Synchrony Respiratory motion tracking system of a robot CyberKnife. Materials and Methods: The study subjects included 24 liver tumor patients who underwent CyberKnife treatment, which included 64 times of treatment with the Synchrony Respiratory motion tracking system ($Synchrony^{TM}$). The treatment involved inserting 4 to 6 acupuncture needles into the vicinity of the liver tumor in all the patients using ultrasonography as a guide. A treatment plan was set up using the CT images for treatment planning uses. The position of the acupuncture needle was identified for every treatment time by Digitally Reconstructed Radiography (DRR) prepared at the time of treatment planning and X-ray images photographed in real-time. Subsequent results were stored through a Motion Tracking System (MTS) using the Mtsmain.log treatment file. In this way, movement of the tumor was measured. Besides, the accuracy of radiosurgery using CyberKnife was evaluated by the correlation errors between the real-time positions of the acupuncture needles and the predicted coordinates. Results: The maximum and the average translational movement of the liver tumor were measured 23.5 mm and $13.9{\pm}5.5\;mm$, respectively from the superior to the inferior direction, 3.9 mm and $1.9{\pm}0.9mm$, respectively from left to right, and 8.3 mm and $4.9{\pm}1.9\;mm$, respectively from the anterior to the posterior direction. The maximum and the average rotational movement of the liver tumor were measured to be $3.3^{\circ}$ and $2.6{\pm}1.3^{\circ}$, respectively for X (Left-Right) axis rotation, $4.8^{\circ}$ and $2.3{\pm}1.0^{\circ}$, respectively for Y (Crania-Caudal) axis rotation, $3.9^{\circ}$ and $2.8{\pm}1.1^{\circ}$, respectively for Z (Anterior-Posterior) axis rotation. In addition, the average correlation error, which represents the treatment's accuracy was $1.1{\pm}0.7\;mm$. Conclusion: In this study real-time movement of a liver tumor during the radiosurgery could be verified quantitatively and the accuracy of the radiosurgery with the Synchrony Respiratory motion tracking system of robot could be evaluated. On this basis, the decision of treatment volume in radiosurgery or conventional radiotherapy and useful information on the movement of liver tumor are supposed to be provided.

• Journal of Acupuncture Research
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• v.20 no.5
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• pp.118-132
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• 2003

Objective: The aim of this study was to investigate the effects of Joksamni(ST36) combination on NAD PH-diaphorase, neuronal nitric oxide synthase(nNOS), neuropeptide Y(NPY) and vasoactive intestinal peptide (VIP) in the cerebral cortex of spontaneously hypertensive rat. Methods: The experimental groups were divided into four groups: Normal, Joksamni(ST36), Joksamni(ST36)+Eumneungcheon(SP9), and Joksamni(ST36)+Gokji(LI11). Needles were inserted into acupoints at the depth of 0.5cm with basic insertion method. Electroacupuncture was done under the condition of 2Hz electrical biphasic pulses with continuous rectangular wave lasting for 0.2ms until the muscles produced visible contractions. Such stimulation was applied continuously for 10 minutes, 1 time every 2 days for 10 sessions of treatments. Thereafter we evaluated changes in NADPH-d positive neurons histochemically and changes in nNOS, NPY and VIP positive neurons immunohistochemically. Results: The optical densities of NADPH-d positive neurons of the Joksamni(ST36)+Eumneungcheon(SP9) group in all areas of cerebral cortex and Joksamni(ST36)+Gokji(LI11) group in primary somatosensory cortex, visual cortex, auditory cortex, perirhinal cortex were significantly increased as compared to the Joksamni(ST36) group. The optical densities of NADPH-d positive neurons of the Joksamni(ST36)+Gokji(LI11) group were significantly decreased as compared to the Joksamni(ST36)+Eumneungcheon(SP9) group with the exception of primary somatosensory cortex. The optical densities of nNOS positive neurons of the Joksamni(ST36)+Eumneungcheon(SP9) group in all areas of cerebral cortex and Joksamni(ST36)+Gokji(LI11) group in auditory cortex, perirhinal cortex, insular cortex were significantly increased as compared to the Joksamni(ST36) group. The optical densities of nNOS positive neurons of the Joksamni(ST36)+Gokji(LI11) group were significantly decreased in all areas of cerebral cortex as compared to the Joksamni(ST36)+Eumneungcheon(SP9) group. The optical densities of NPY positive neurons of the Joksamni(ST36)+Gokji(LI11) group were significantly decreased in primary motor cortex, primary somatosensory cortex, cingulate cortex as compared to the Joksamni (ST36) and Joksamni(ST36)+Eumneungcheon(SP9) groups. The optical densities of VIP positive neurons of the Joksamni(ST36)+Eumneungcheon(SP9) group were significantly increased in all areas of cerebral cortex except for cingulate cortex as compared to the Joksamni(ST36) group. The optical densities of VIP positive neurons of the Joksamni(ST36)+Gokji(LI11) group were significantly decreased in auditory cortex, cingulate cortex, perirhinal cortex as compared to the Joksamni(ST36) group. The optical densities of VIP positive neurons of the Joksamni(ST36)+Gokji(LI11) group were significantly decreased in all areas of cerebral cortex as compared to the Joksamni(ST36)+Eumneungcheon(SP9) group. Conclusions: The result demonstrated that electroacupuncture on Joksamni(ST36) and its combination change the activities of the NO system and peptidergic system in the cerebral cortex of SHR and that acupoint combination is one of the important parameters for the effects.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.16 no.2
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• pp.47-58
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• 2012

Objectives : The purpose of the present study is to grasp and provide basic data necessary for the establishment of korean healthcare policies in future. Methods : A questionnaire developed by the author was distributed to 299 students of D University located in Busan and collected thereafter from March 5 to June 1, 2012. Statistical processing of the data obtained was conducted using the SPSS WIN IBM 20.0 program to indicate outcomes in frequencies and percentages. Results : The results of the survey are as follows. 1. The number of students who were mainly using korean hospitals/clinics was 6(2.0%). The most important factor in selecting korean medical institutions was 'medical technology'. 2. The treatment that was received the most frequently and the most reliable at korean medical institutions was acupuncture. The most frequent reason for taking korean medicine was 'prescriptions tailored to constitutions' and the most frequent reason for avoiding korean medicine was 'high prices'. 3. There was few number of students who knew that car insurance coverage for traffic accidents include treatment at korean clinics. and who knew about 'permitted standard herbal medicine', 'the use of disposable needles', 'wild ginseng pharmacopuncture'. 4. Among items necessary for the development of korean medicine, 'treatment technology with fast and high effects' was the most frequently selected. Conclusions : University students' preference for and perception of korean medicine were shown to be very low. It is considered that public relations should be reinforced to implant correct perception of korean medicine in university students who will be major users of hospitals and clinics.

• Journal of Veterinary Clinics
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• v.23 no.2
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• pp.102-104
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• 2006

The purpose of this study was to document the histology of canine acupoints. Acupunctural needles were inserted by 0.5 to 1 cm depth into acupoints Nei-guan (Inner pass, PC06), Gan-shu (Liver Association Point, BL18), Shen-shu (Kidney Association Point, BL23) and Pangguang-shu (Bladder Association Point, BL28) in 4 dogs, and the tissues around the acupoints were examined. Light microscopy was used to observe the surrounding structures of each point. Nerve fibres, small vessels and muscle spindles were found around the tip of the needle in every case, although they occurred not so often at nonacupoint in nearby region or nonacupoint in the areas, such as skin, subcutaneous tissue and muscle. Therefore, it is suggested that nerve fibres, small vessels and muscle spindles may be potential acupoint receptors.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.4
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• pp.80-88
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• 2012

Background and Objective : Atrophic scars are the most common complication of acne. Many modalities are proposed but each does not yield satisfactory clinical outcomes. Among therapeutic modalities of acne scars, subcision is a simple, safe procedure with a different and basic mechanism for correcting atrophic and depressed scars. However, there are few reports about such procedure. This study performed to evaluate the effect of subcision treatment on atrophic acne scar. Methods : Five patients with atrophic acne scars of various types(rolling, superficial and deep boxcar, pitted and icepick) were treated by superficial dermal undermining with 25~27 gauge needles. We used GASC(Global Acne Scarring Classification). Satisfaction degree was asked from the patients. Results and Conclusions : After observing patients satisfaction, comparing case photos and GASC, it can be considered that subcision treatment brings great results when performed on atrophic post acne scars.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.6
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• pp.689-694
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• 2014

We report a female small cell lung cancer patient in the extensive stage(T3N3Mx). After 6 cycles of chemotherapy combined radiation therapy, she received inpatient Korean medical care including herbal medicine, acupuncture therapy and concurrent western oral medications of opioid analgesics and anti-anxiety agent. The chief complaint was right side thoracic wall pain which had started after chemotherapy and was not effectively controlled by analgesics. For this condition, we treated her with 2Hz of constant electrical stimulation on Jiaji (Ex-B2) points T5-T7 laterally (right) using three needles for 20 minutes once a day for 9 days. With every session of electrical acupuncture treatment, thoracic pain decreased acutely. Korean medicine treatments including Jiaji (Ex-B2) point stimulation might be tried for lung cancer patients with uncontrolled thoracic pain at least for the acute analgesic effect.

• Korean Journal of Acupuncture
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• v.31 no.3
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• pp.125-135
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• 2014

Objectives : Warm needling is the method combining the effects of acupuncture and moxibustion. In modern clinics, warm needling is only affected by treatment time or frequency. We need to study the physical characteristics of warm needles currently used in clinics in order to develop more efficient and economical treatments. Methods : We collected various warm needle specimens and analyzed chemical constitutions, measured heat transfer velocity, micro Vicker's hardness and specific resistance. We studied the relationship between heat transfer velocity and micro Vicker's hardness as well as that between heat transfer velocity and specific resistance. Results : The heat transfer velocity of the Silver_HL was 3.3 mm/sec, of the Au alloy group was 1.3~2.6 mm/sec, and Silver_IN, Silver_ZK and SS groups was less than 0.3 mm/sec. We therefore concluded that the needle composed of Ag has the best heat transfer velocity. In the Micro Vicker's hardness test, Vicker's hardness of the Au alloy group was 159~170 Hv, of Silver_HL was 181 Hv, and of the Silver_IN, Silver_ZK, SS group was 450.8~519 Hv. In the Silver_IN, Silver_ZK and SS groups, hardness was inversely proportial to thermal conductivity. In the specific resistance test, the specific resistance of Silver_HL was the lowest, that of the Au alloy group was the second lowest, and that of the Silver_IN, Silver_ZK, SS groups were the highest. Conclusions : We concluded that the needle composed of Ag has the best heat transfer velocity, highest electric conductivity and thermal conductivity, therefore the needle composed of Ag is suitable for warm needling.