• The Journal of Korean Society of Virology
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• v.29 no.4
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• pp.271-281
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• 1999

The nested polymerase chain reaction (PCR) assay was used to determine the sequences of reverse transcriptase (RT) codons 41, 67, 70, 210, 215 and 219 of human immunodeficiency virus-1 (HIV-1) pol gene. Template DNA was obtained from uncultured peripheral blood mononuclear cells from 27 Korean HIV-1 infected patients treated with ZDV and Korean red ginseng. The second PCRs were done for 2 separated regions (RT codons $13{\sim}98$ and $152{\sim}259$) with $5\;{\mu}l$ of the first PCR productNucleotide sequences were determined by direct sequencing. In the 27 patients, CD4+ cell count decreased from $230{\pm}117/{\mu}l$ to $152{\pm}162/{\mu}l$ for $46{\pm}26$ months (Mo), and actual duration of ZDV intake was $72{\pm}16$ Mo. In the 16 patients who had been treated with ZDV therapy ${\ge}25$ Mo, the incidences of 70R, 215F/Y, and 41L were 61%, 28% and 22%, respectively and those of 67N, 210W and 219Q were 17%. The incidences of 215F/Y were 6.7% for group ${\le}12$ Mo treatment, 22.7% for group with 13 to 24 Mo, and 27.8% for group ${\ge}25$ Mo. There was no mutation in 9 patients. It might be associated with the interruption of ZDV therapy for more than 6 months in 6 patients. This study shows that the detection of mutation could be useful prognostic marker with other clinical and virological data, and very low mutation rate is dectected compared to overseas reports.

• Journal of Energy Engineering
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• v.26 no.4
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• pp.107-117
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• 2017

Since South Korea started to apply Renewable Portfolio Standard (RPS) in 2012, there have been huge investment for deploying renewable technologies. Recently, the government determined to incentivize battery energy storage system(BESS) with renewable generations in order to induce the improvement of dispatching capability. In this paper, the annual pattern of PV generation based on actual generation data in South Korea is analyzed and the duration curve of capacity factor is proposed in order to provide the simplified analyzing methodology of present support policy for additional BESS installation for decision maker who is responsible for supply and demand planning. With suggested methodology, the range of appropriate BESS size with respect to the variation of system marginal price(SMP) and renewable energy certificate(REC) price can be derived briefly, and decision makers easily evaluate the effect of support scheme. Current policy for BESS installation support present additional BESS-related installation policy may give incentives to developers partially, however, the dependence between BESS size and benefit components (SMP and REC) can limit the deployment of the various portfolios of the BESS. Therefore, when improving the current policy in future, addressing the dependence between the technical aspects of battery size and the benefit components separately by the technical and economical parts is needed to set the suitable compensation rules for the renewable generation and BESS.

• Journal of Biomedical Engineering Research
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• v.23 no.1
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• pp.61-72
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• 2002

In this parer, a new harmonic imaging technique is Proposed and evaluated experimentally. In the Proposed method. a weighted chirp signal with a hanning window is transmitted. The RF samples obtained on each array element are individually compressed by correlating with the reference signal defined as the 2nd harmonic component($2f_0$) of a transmitted chirp signal generated in a square-law system. The correlator output will then consist of the compressed version of the $2f_0$ component generated in tissue and the crosscorrelation sequence of the fundamental($f_0$) and 2f$_{0}$components. The Proposed method uses the compressed $2f_0$ component to form an image. for which the crosscorrelation term should be suppressed below at least -50dB. The Proposed method has two process, 2f$_{0}$-correlation and $2f_0$-correlation(PI) . $2f_0$-correlation can successfully eliminate the $f_0$ component with a single transmit-receive events and therefore is more efficient than the conventional Pulse inversion method in terms of the frame rate. 2i)-correlation(Pl) Performs pulse compression after applying pulse inversion method for the 2nd harmonic image with high resolution and SNR. Another advantage of the proposed method is that the SNR of 2nd harmonic imaging can be improved without limitation by increasing the duration of the chirp signal. The proposed method was verified through both the computer simulations and actual experiments .ts .

• Journal of Construction Engineering and Project Management
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• v.5 no.1
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• pp.11-19
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• 2015

This paper presents optimized artificial neural networks (ANNs) claims prediction and decision awareness framework that guides owner organizations in their pre-bid construction project decisions to minimize claims. The framework is composed of two genetic optimization ANNs models: a Claims Impact Prediction Model (CIPM), and a Decision Awareness Model (DAM). The CIPM is composed of three separate ANNs that predict the cost and time impacts of the possible claims that may arise in a project. The models also predict the expected types of relationship between the owner and the contractor based on their behavioral and technical decisions during the bidding phase of the project. The framework is implemented using actual data from international projects in the Middle East and Egypt (projects owned by either public or private local organizations who hired international prime contractors to deliver the projects). Literature review, interviews with pertinent experts in the Middle East, and lessons learned from several international construction projects in Egypt determined the input decision variables of the CIPM. The ANNs training, which has been implemented in a spreadsheet environment, was optimized using genetic algorithm (GA). Different weights were assigned as variables to the different layers of each ANN and the total square error was used as the objective function to be minimized. Data was collected from thirty-two international construction projects in order to train and test the ANNs of the CIPM, which predicted cost overruns, schedule delays, and relationships between contracting parties. A genetic optimization backward analysis technique was then applied to develop the Decision Awareness Model (DAM). The DAM combined the three artificial neural networks of the CIPM to assist project owners in setting optimum values for their behavioral and technical decision variables. It implements an intelligent user-friendly input interface which helps project owners in visualizing the impact of their decisions on the project's total cost, original duration, and expected owner-contractor relationship. The framework presents a unique and transparent hybrid genetic algorithm-ANNs training and testing method. It has been implemented in a spreadsheet environment using MS Excel$^{(R)}$ and EVOLVERTM V.5.5. It provides projects' owners of a decision-support tool that raises their awareness regarding their pre-bid decisions for a construction project.

• Environmental Analysis Health and Toxicology
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• v.11 no.1_2
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• pp.19-29
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• 1996

Human exposure to volatile compounds in tap water can occur from inhalation and dermal absorption as well as direct ingestion. The relative contribution to total human exposure from these pathways has been considered to be important especially for VOC's (volatile organic compounds). In an attempt to reduce the uncertainty of the risk assessment, it has been suggested that the exposure assessment process could be significantly improved by adopting Monte-Carlo simulation. However, there is no actual data in Korea for each exposure parameter to determine the level of exposure, and the distributional pattern. Therefore, we surveyed water use patterns and behavior related to multi-route exposure to VOC's in household tap water in Korea, and compared these values to the those in western countries. In the first survey, we calculated daily water intake using data from a sample of 1322 persons of several cities in Korea. In the second survey, we obtained questionnaire data on exposure time for showering, bathing and household activities, and tap water intake from 851households in Korea. In the last survey, we measured the exposure parameters (exposure time, water use rate etc.) related to showers, baths, toilets, dish washing, washing and cooking, and tap water intake was surveyed. Also, the subjects were measured their body weight, height and tidal volume, etc. A diary, a flow meter and a measuring cup were used to measure these values as precisely as possible. Average daily water intake was ranged 0.79-1.71 L/day for adults in three surveys. Tap water intake measured by log-sheet during one week in third survey was 1.26 (average), 1.98 L/day (90 percentlie), respectively. These results were comparable with results from EPA (1.4, 2L/day). The average amount of water used by housewives in the third survey was 515.0 $\pm$ 564.6L/day. In usual activity, the amount of water used in the bathroom, the laundry and the kitchen was 140.0 $\pm$ 538.9, 148.0 $\pm$ 174.5, 229.3 $\pm$ 205.4 L/day, respectively. Exposure parameters such as water intake rate, exposure duration, body weight, inhalation rates in surveyed data of Korean people differed from those published from western countries. This could be attributed to variations in lifestyle, dietary habits and physiological characteristics.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.11
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• pp.99-107
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• 2013

Controller area network (CAN) was designed for multiplexing communication between electronic control units (ECUs) in vehicles and thus for decreasing the overall wire harness. The increasing number of ECUs causes the CAN bus overloaded and consequently the error probability of data transmission increases. Since the time duration for the data transmission is proportional to CAN frame length, it is desirable to reduce the frame length. In this paper, a CAN message compression method is proposed using Data Length Code (DLC) and compression area selection algorithm to reduce the CAN frame length and the error probability during the transmission of CAN messages. By the proposed method, it is not needed to predict the maximum value of the difference in successive CAN messages as opposed to other compression methods. Also, by the use of DLC, we can determine whether the received CAN message has been compressed or not without using two ID's as in conventional methods. By simulations using actual CAN data, it is shown that the CAN transmission data is reduced up to 52 % by the proposed method, compared with conventional methods. By using an embedded test board, it is shown that 64bit EMS CAN data compression can be performed within 0.16ms and consequently the proposed algorithm can be used in automobile applications without any problem.

• Journal of Environmental Health Sciences
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• v.45 no.6
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• pp.646-657
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• 2019

Objectives: The purpose of this study was to suggest methods to investigate continuous monitoring of concentration levels and assess the exposure of individuals considering the actual time activity of residents for formaldehyde and particulate matter (PM₁₀, PM_2.5) in the indoor and outdoor air of a house, assess the health risks of children and adults based on the results of the exposure assessment, and provide basic data on studies for assessing exposure and health risks in Korea in the future. Methods: The concentration levels of formaldehyde and particulate matter were measured in a family home in Gyeonggi-do Province from April 25 to July 31, 2019, using electrochemical sensors (formaldehyde) and light scattering sensors (PM₁₀, PM_2.5). Risk assessment by the duration of exposure by time activity was performed by dividing between weekdays and weekends, and indoors and outdoors. Results: The greatest level of carcinogenic risk from inhaling formaldehyde was indoors during the weekdays for both children and adults. For children, the risk was at 7.5 per approximately 10,000 people, and for adults, the risk was at 4.1 per approximately 10,000 people. PM₁₀ and PM_2.5 also showed the greatest values indoors during the weekdays, with children at 1.7 people and 1.4 per approximately 100 people, respectively, and adults at 8.2 per approximately 1,000 and 1.8 per approximately 100 people, respectively. Conclusions: The risks of formaldehyde, PM₁₀ and PM_2.5 were shown to be high indoors. Therefore, consideration of exposure assesment for each indoor pollutant and management of indoor air quality is necessary.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.2
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• pp.141-151
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• 2013

The nano-surface modification techniques could be classified; internal modifications which enhance surface roughness and porosity in nano level and external modifications as nano particle coating. Nano-modified implant surface has various morphograpies such as nanotube, nanopit, nanonodule and polymorphic structures. Creating surface depends upon preparation method and material, however, there is no standard preparation technique not yet. The nano-modified surfacet is electrochemically stable comparing with the surface modified in micron level. Nano-modified surface has little cytotoxicity, stimulates osteoblast proliferation and differentiation. Moreover, it decreases soft tissue intervention by interrupting the proliferation of fibroblast. Nanostructure has similar size and shape with cells and proteins, consequently leads to good biocompatibility and enhanced osseointegration. However, the actual effect in vivo is limited, due to the distance of effect. Even if nano-modified surface has antibiotic property due to photocatalysis, short duration time makes clinical application questionable. Further investigations should focus on the optimal nano-modified surface, which has many potentials.

• The Journal of the Convergence on Culture Technology
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• v.4 no.1
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• pp.57-65
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• 2018

The purpose of this study was to investigate the factors affecting the actual condition and effectiveness of orthodontic treatment among some dental hygienists and students. This study was carried out from September to December, 2016 to describe the purpose of the study and the method of writing the questionnaire for some dental hygienists and students. The final 430 sections were analyzed and analyzed using PASW Statistics 18.0. First, the duration of orthodontic treatment was 34.4% for college students, 36.9% for orthodontic treatment for less than 2 ~ 3 years, and 62.3% for internal motivation. The factors affecting the orthodontic treatment effect were the patient's cooperativeness and the hospital's scale was the lowest. The higher the grade level, the more the clinical experience and dental part-time experience were, the higher the correlation between dental specialty and dental hygienist's medical service, education and counseling was .521(P<0.001). The higher the level of cooperation, the higher the grade level, the more dental treatment and orthodontic treatment experience, the lower the level of family co - operation. Therefore, it is important to emphasize the importance of cooperation of orthodontic patients and to develop a strategic program for each individual patient.

• Journal of Korea Water Resources Association
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• v.39 no.5 s.166
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• pp.383-394
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• 2006

This study is for the inundation damage analysis caused by levee break, and for the applicability of GIS tool to make inundation map in the Jungrang stream basin which is one of the representative urbanized area in Korea. The FLDWAV was applied to the actual flood in 1998 to calibrate the parameters, and was used under the flood conditions of 100, 200 years and PMF for the analysis of inundation caused by the levee breach. As the conditions of the levee break, the duration of break(10, 30, 60 min), the width of break(10, 20, 30m) and the location of the break are considered. We found out that the range and the volume of the inundation are strongly influenced by the location of the levee break, the break width in order. And, we compared the two processes of making the inundation map using WMS and ArcView model. The Process 1 which use only WMS has the benefit by its simplicity but there could be considerable errors in making the inundation map, while Process 2 where the ArcView model is introduced to WMS has the capability of making detailed topography map but needs more process time. This study could contribute to levee breach flood analysis and making flood map to establish the EAP(Emergency Action Plan) in the urban basin.